Influence of tocopherol on tumour cell oxygenation.

Abstract:

:Tocopherol, a well known tissue anti-oxidant, given before local X-ray irradiation of 2 transplantable rat tumours was previously found to increase significantly the effect of irradiation. In the present study tocopherol did not influence the development of tumour necroses during growth of a transplantable rat hepatoma. The tumour tissue oxygenation of a transplantable rat sarcoma was neither found to be influenced by tocopherol. This suggests that an enhanced tumour radio-sensitivity by tocopherol is probably not explained by an influence on tumour cell oxygenation.

journal_name

Cancer Lett

journal_title

Cancer letters

authors

Kågerud A,Klintenberg C,Lund N,Peterson HI

doi

10.1016/s0304-3835(78)80037-8

subject

Has Abstract

pub_date

1978-10-01 00:00:00

pages

185-9

issue

4

eissn

0304-3835

issn

1872-7980

pii

S0304-3835(78)80037-8

journal_volume

5

pub_type

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