Abstract:
:The presence of the neuron specific enolase (NSE) has been tested by sandwich enzyme immunoassay in cerebrospinal fluid (CSF) of rats after intrastriatal injection of various amounts of kainic acid (KA). Incremental release of NSE was observed in CSF for increasing concentrations of injected KA. Still, a significant decrease of NSE striatal content was detected only with the two maximal amounts of KA infused. These data indicate that measurements of NSE in CSF might be a more sensitive index of neuronal damage than the actual assay within the tissue, and also present the advantage of being a non-invasive method of investigation.
journal_name
Neurosci Lettjournal_title
Neuroscience lettersauthors
Steinberg R,Scarna H,Pujol JFdoi
10.1016/0304-3940(84)90090-9subject
Has Abstractpub_date
1984-03-23 00:00:00pages
147-50issue
2eissn
0304-3940issn
1872-7972pii
0304-3940(84)90090-9journal_volume
45pub_type
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
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abstract::Guanidine, the active ingredient extracted from Galega officinalis, is introduced as a ligand for imidazoline I2 receptor (I2R) because guanidine decreased plasma glucose via an activation of I2BR to increase glucose uptake into skeletal muscle isolated from Wistar rats. However, the signals for this action of guanidi...
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abstract::The cellular localization of Thy-1 in the chick retina was investigated by selectively destroying certain populations of neurons with toxins. In control retinae four weeks after intravitreal injection of vehicle, there was strong immunoreactivity for Thy-1 in the nerve fibre layer, ganglion cell layer and inner plexif...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(91)90164-o
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2008.01.014
更新日期:2008-07-04 00:00:00
abstract::Considering the multiplicity of symptoms associated with multiple sclerosis (MS), there is possibility that hypocretin system function might be involved in the pathogenesis of the disease. The current study aimed to investigate the hypocretin-1 levels in cerebrospinal fluid (CSF) of MS patients in relation to differen...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2010.02.062
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journal_title:Neuroscience letters
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(87)90036-x
更新日期:1987-01-02 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1999-02-26 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/s0304-3940(03)00899-1
更新日期:2003-10-30 00:00:00
abstract::Studies of cognitive behavior in rodent models of Alzheimer's disease (AD) are the mainstay of academic and industrial efforts to find effective treatments for this disorder. However, in the majority of such studies, the nature of rodent behavioral tests is considerably different from the setting associated with cogni...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2017.04.049
更新日期:2017-05-22 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(86)90664-6
更新日期:1986-02-14 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2009.07.035
更新日期:2009-09-29 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2011.10.021
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journal_title:Neuroscience letters
pub_type: 杂志文章,评审
doi:10.1016/j.neulet.2020.135058
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2012-08-08 00:00:00
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journal_title:Neuroscience letters
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更新日期:1986-10-08 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:2000-12-15 00:00:00
abstract::The acute thermoregulatory effect of microinjection of capsaicin into the nucleus raphe dorsalis (NRD) has been studied in anesthetised rats. Application of capsaicin (20 micrograms) into the NRD increased the tail skin temperature and decreased the body temperature. In animals that had previously been treated with ca...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(87)90297-7
更新日期:1987-03-31 00:00:00
abstract::Calcium homeostasis in synaptosomes is altered during ageing. The cytosolic free calcium concentration, [Ca2+]i was determined in synaptosomes and crude synaptosomal fractions from 3- and 24-month-old rats with the fluorescent indicator quin-2. The [Ca2+]i were around two times higher in 24-month-old rats than in adul...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90234-0
更新日期:1988-06-07 00:00:00
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journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/j.neulet.2012.03.055
更新日期:2012-05-10 00:00:00
abstract::In the present study we have used slice cultures of hippocampus and in situ hybridization techniques in order to study the ability of hippocampal neurons to synthesize CCK mRNA in the absence of extrinsic afferents. Our results show that very similar types of hippocampal neurons express CCK mRNA in culture as in situ....
journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1994-05-19 00:00:00
abstract::To clarify the possible involvement of protein kinase (PK) C activation in the excitation and sensitization of polymodal receptors (PMRs), the effects of phorbol 12,13-dibutyrate (PDBu) on PMRs were studied in canine testis-spermatic nerve preparations in vitro. Application of PDBu (10(-7), 10(-6), AND 10(-5) M) for 5...
journal_title:Neuroscience letters
pub_type: 杂志文章
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更新日期:1996-03-08 00:00:00
abstract::L1 is a highly conserved cell adhesion molecule with complete homology of the cytoplasmic domain between the known mammalian protein sequences. Since the cytoplasmic domains of other adhesion molecules have been shown to influence adhesion, we have investigated the effects of deletion of the cytoplasmic domain on the ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(95)12100-i
更新日期:1995-11-24 00:00:00
abstract::This investigation was designed to determine the responses of neurons in the posterior group of nuclei (PO) to tooth pulp stimulation. Eighteen tooth pulp-driven (TPD) neurons were recorded in 9 cats anesthetized with nitrous oxide and halothane, 14 of them in the medial part (POM) and the remainder in the lateral par...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(88)90091-2
更新日期:1988-11-11 00:00:00
abstract::In the rat, electrical stimulation of the cranial end of the cut hepatic branch of the vagus nerve modulated gastric contractions. When the gastric contraction rate reached approximately one per min, nerve stimulation caused total suppression. When the stomach was free of contraction, nerve stimulation initiated one. ...
journal_title:Neuroscience letters
pub_type: 杂志文章
doi:10.1016/0304-3940(85)90097-7
更新日期:1985-01-07 00:00:00