Decreased sensitivity of neurons in the basolateral amygdala to dopamine and noradrenaline iontophoresis after a kindling stimulus.

abstract：:In order to study the ocular dominance and responsiveness of cells in the deafferented visual cortex, the geniculate and the callosal inputs were interrupted in adult cats by either simultaneous (OTCCX) or separate surgical transection of the optic tract (OTX) and the posterior corpus callosum (CCX). Unit recording wa...

journal_title：Experimental neurology

authors： Yinon U,Achiron A

更新日期：1988-03-01 00:00:00

abstract：:Historically, the immune response after spinal cord injury was considered largely detrimental owing to the release of neurotoxic factors. While there is validity to this view, there is much greater heterogeneity of immune cells than was previously realized. Associated with this heterogeneity of immune cell subtypes, t...

journal_title：Experimental neurology

authors： Plemel JR,Wee Yong V,Stirling DP

更新日期：2014-08-01 00:00:00

abstract：:Microfilaments (MFs) play an important role in wound healing and other regenerative events. The purpose of this study was to characterize changes in the distribution of MFs in traumatized auditory epithelia and compare these changes between avian (regenerating) and mammalian (nonregenerating) ears. Chicks and guinea p...

journal_title：Experimental neurology

authors： Raphael Y,Altschuler RA

更新日期：1992-01-01 00:00:00

abstract：:Angiotensin II type 1 receptor (AT1R) blocker (ARB) has been reported to modify hypertensive cerebrovascular changes; however, it is not clear whether its protective effects are independent of blood pressure. The aim of this study was to clarify the role of AT1R-mediated signals in cerebral circulation by the chronic ...

journal_title：Experimental neurology

authors： Kumai Y,Ooboshi H,Ago T,Ishikawa E,Takada J,Kamouchi M,Kitazono T,Ibayashi S,Iida M

更新日期：2008-04-01 00:00:00

abstract：:The effects of intranigral iron injection on dopamine (DA) release and content in the caudate putamen (CPu) and their relationship to DA-related behavioral response were investigated in rats. Different concentrations of FeCl(3) (10, 20, and 40 microg) and saline were injected separately into the left substantia nigra....

journal_title：Experimental neurology

authors： Junxia X,Hong J,Wenfang C,Ming Q

更新日期：2003-08-01 00:00:00

abstract：:Substantial residual neurological function may persist after spinal cord injury (SCI) with survival of as few as 5-10% of the original number of axons. A detailed understanding of the relationships among the severity of injury, the number and origin of surviving axons at the injury site, and the extent of neurological...

journal_title：Experimental neurology

authors： Fehlings MG,Tator CH

更新日期：1995-04-01 00:00:00

abstract：:Infusions of an excitant amino acid, N-methyl-D-aspartate (NMDA) into the inferior colliculus (IC) render normal rats susceptible to audiogenic seizures (AGS) and/or spontaneous audiogenic-like seizures without tonic components. The excess excitant amino acid in the IC and the anticonvulsant effects of NMDA antagonist...

journal_title：Experimental neurology

authors： Browning RA,Wang C,Faingold CL

更新日期：1991-05-01 00:00:00

abstract：:Modification of GABAergic inhibition is an intensely investigated hypothesis guiding research into mechanisms underlying temporal lobe epilepsy (TLE). Seizures can be initiated by blocking γ amino butyric acid type A (GABAA receptors, GABARs), which mediate fast synaptic inhibition in the brain, and controlled by drug...

journal_title：Experimental neurology

authors： Joshi S,Rajasekaran K,Kapur J

更新日期：2013-06-01 00:00:00

abstract：:Fatigue indices and succinic dehydrogenase (SDH) activities were determined in the extensor digitorum longus (EDL) and soleus muscles of the hind limb and the extensor carpi radialis longus of the forelimb in control and dystrophic mice aged 4 to 26 weeks. A good correlation was found between SDH activities and fatigu...

journal_title：Experimental neurology

authors： Parry DJ,Desypris G

更新日期：1985-02-01 00:00:00

abstract：:Periodic changes in ovarian steroid levels during fertility cycles affect learning both in humans and in rats in parallel with electrophysiological and morphological fluctuations in selective neuronal populations. In particular, during the estrous cycle of the female rat, hippocampal CA1 region undergoes cyclic modifi...

journal_title：Experimental neurology

authors： Crispino M,Stone DJ,Wei M,Anderson CP,Tocco G,Finch CE,Baudry M

更新日期：1999-10-01 00:00:00

abstract：:It is clear that there are events which occur in response to neuromuscular activity that are essential to maintain normal muscle properties. Two factors though to influence muscle contractile properties are tension and electrical activity. To study these variables the hind limbs of 10 postpubertal female Sprague-Dawle...

journal_title：Experimental neurology

authors： Winiarski AM,Roy RR,Alford EK,Chiang PC,Edgerton VR

更新日期：1987-06-01 00:00:00

abstract：:The human small heat shock proteins (HSPBs) form a family of molecular chaperones comprising ten members (HSPB1-HSPB10), whose functions span from protein quality control to cytoskeletal dynamics and cell death control. Mutations in HSPBs can lead to human disease and particularly point mutations in HSPB1 and HSPB8 ar...

journal_title：Experimental neurology

authors： La Padula V,Staszewski O,Nestel S,Busch H,Boerries M,Roussa E,Prinz M,Krieglstein K

更新日期：2016-12-01 00:00:00

abstract：:The vibrissae of rats were shaved from one side of the face daily for 10 days. To see whether or not this treatment had an effect on crossed and uncrossed striatal afferent connections from the midbrain, the tract tracer horseradish peroxidase was applied to the caudate-putamen on day 11. When the tracer was deposited...

journal_title：Experimental neurology

authors： Huston JP,Morgan S,Lange KW,Steiner H

更新日期：1986-08-01 00:00:00

abstract：:The retrograde axonal transport mechanism of motor neurons has been exploited to deliver the gene encoding Glial cell line-derived neurotrophic factor (GDNF) into the central nervous system to provide trophic support following injury. A nonviral gene delivery system, consisting of a monoclonal antibody (MC192) that bi...

journal_title：Experimental neurology

authors： Barati S,Hurtado PR,Zhang SH,Tinsley R,Ferguson IA,Rush RA

更新日期：2006-11-01 00:00:00

abstract：:The cellular events in traumatic brain injury (TBI) are complicated, and the factors mediating neurotrophins to protect and repair the injured brain cells are only beginning to be identified. This study examined the effect of dexamethasone (DEX) on neurotrophin-3 (NT-3) expression following TBI. Levels of NT-3 mRNA an...

journal_title：Experimental neurology

authors： Yang JT,Lee TH,Weng HH,Chang CN,Chen WC,Cheng WC,Wu JH

更新日期：2005-04-01 00:00:00

abstract：:Increasing evidence indicates that the cytokines, tumor necrosis factor (TNF), interleukin-1, and/or interferon-gamma, may play a crucial role in the pathogenesis of multiple sclerosis. Several reports demonstrated that inhibition of TNF is highly protective in experimental allergic encephalomyelitis (EAE) when sensit...

journal_title：Experimental neurology

authors： Martin D,Near SL,Bendele A,Russell DA

更新日期：1995-02-01 00:00:00

abstract：:We have previously demonstrated an opioid link in nucleus accumbens (NAc) that mediates antinociception produced by a novel ascending pain modulation pathway. For example, noxious stimulation induces heterosegmental antinociception that is mediated by both mu- and delta-opioid receptors in NAc. However, spinal intrath...

journal_title：Experimental neurology

authors： Gear RW,Levine JD

更新日期：2011-06-01 00:00:00

abstract：:Infant, juvenile, and adult brain growth is modulated by corticosterone. This study was designed to determine whether such modulation is confined to certain specific brain areas, and if the pattern of growth revealed is consistent across strains of rats. Young female Sprague-Dawley-derived rats were either adrenalecto...

journal_title：Experimental neurology

authors： Thomas TL,Devenport LD

更新日期：1988-12-01 00:00:00

abstract：:The cell death induced by hydroxyl radicals generated by Cu-phenanthroline and peroxynitrite generated by 3-morpholinosydnonimine hydrochloride (SIN-1) in rat primary cortical neuronal cultures was compared with the apoptotic death induced by staurosporine and the necrotic death induced by glutamate. Both SIN-1 and Cu...

journal_title：Experimental neurology

authors： Hill IE,Murray C,Richard J,Rasquinha I,MacManus JP

更新日期：2000-03-01 00:00:00

abstract：:Ca2+ influx through NMDA receptor-gated channels and the subsequent rise in intracellular Ca2+ concentration ([Ca2+]i) have been implicated in cytotoxic processes that lead to irreversible neuronal injury. While many studies have focused on cytosolic Ca2+ homeostasis, much less is known about Ca2+ fluxes in subcellula...

journal_title：Experimental neurology

authors： Peng TI,Jou MJ,Sheu SS,Greenamyre JT

更新日期：1998-01-01 00:00:00

abstract：:Frontotemporal dementia (FTD) is the second most common cause of presenile dementia. Here we have investigated the frequency of the epsilon4 allele of the Apolipoprotein (APOE) gene in FTD and in other non-Alzheimer forms of dementia related to FTD such as Motor Neurone disease dementia, semantic dementia, progressive...

journal_title：Experimental neurology

authors： Pickering-Brown SM,Owen F,Isaacs A,Snowden J,Varma A,Neary D,Furlong R,Daniel SE,Cairns NJ,Mann DM

更新日期：2000-06-01 00:00:00

abstract：:The effect of frequency potentiation on the postsynaptic potential in granule cells was studied stimulating the perforant path in curarized and urethanized rats. At stimulation frequencies between 2.0-5.0 Hz, synaptic efficacy in eliciting an orthodromic action potential increased despite the hyperpolarization of the ...

journal_title：Experimental neurology

authors： Muñoz MD,Núñez A,García-Austt E

更新日期：1991-07-01 00:00:00

abstract：:The aminergic and cholinergic fibers innervating the hippocampus reach their target regions via the dorsal (dorsal fornix, fimbria, and cingulum) and ventral routes. The plasticity of this innervation after lesions of the dorsal pathway was investigated in the septal, medial, and temporal regions of the adult rat hipp...

journal_title：Experimental neurology

authors： Gasser UE,Dravid AR

更新日期：1987-05-01 00:00:00

abstract：:Diffuse noxious inhibitory controls (DNIC) are very powerful long-lasting descending inhibitory controls which are pivotal in modulating the activity of spinal and trigeminal nociceptive neurons. DNIC are subserved by a loop involving supraspinal structures such as the lateral parabrachial nucleus and the subnucleus r...

journal_title：Experimental neurology

authors： Chebbi R,Boyer N,Monconduit L,Artola A,Luccarini P,Dallel R

更新日期：2014-06-01 00:00:00

abstract：:Copyright ...

journal_title：Experimental neurology

authors：

更新日期：1998-06-01 00:00:00

abstract：:A new procedure was developed for ablating the mammillary nuclei in nonhuman primates via direct visual exposure. Using this technique, monkeys receiving lesions of the mammillary nuclei were compared to control animals after surgery to assess the retention of preoperatively acquired visuospatial discriminations and s...

journal_title：Experimental neurology

authors： Holmes EJ,Jacobson S,Stein BM,Butters N

更新日期：1983-07-01 00:00:00

abstract：:Amyotrophic lateral sclerosis [ALS] is a rapidly progressive neurodegenerative disorder of motor neurons, heralded by the development of cortical hyperexcitability. Reduction of short interval intracortical inhibition [SICI] in ALS, a feature linked to the development of cortical hyperexcitability, may be mediated by ...

journal_title：Experimental neurology

authors： Vucic S,Cheah BC,Kiernan MC

更新日期：2009-11-01 00:00:00

abstract：:An in vivo assay was developed for long-term analyses of Schwann cells at the single cell level. Schwann cells were isolated from sciatic nerves and labeled with the fluorescent gold label Fluoro-Gold. Cells were then transplanted into severed sciatic nerves of young adult rats. Gold-labeled Schwann cells, identified ...

journal_title：Experimental neurology

authors： Daniloff JK

更新日期：1991-10-01 00:00:00

abstract：:A host protein encoded by the gene specifying the scrapie amyloid precursor affects pathogenesis of the transmissible spongiform encephalopathies: Creutzfeldt-Jakob disease (CJD), Gerstmann-Sträussler-Scheinker's syndrome (GSS), and kuru in man, and scrapie in animals. We found a mutation in this gene of two patients ...

journal_title：Experimental neurology

authors： Goldgaber D,Goldfarb LG,Brown P,Asher DM,Brown WT,Lin S,Teener JW,Feinstone SM,Rubenstein R,Kascsak RJ

更新日期：1989-11-01 00:00:00

abstract：:This study uses the saphenous nerve crush model in Thy1-YFP mice and serial transcutaneous imaging to evaluate the rate of nerve regeneration under various FK-506 (tacrolimus) dosing regimens and in the presence of transgenic overexpression of glial cell line-derived neurotrophic factor (GDNF). Thy1-YFP transgenic mic...

journal_title：Experimental neurology

authors： Yan Y,Sun HH,Mackinnon SE,Johnson PJ

更新日期：2011-11-01 00:00:00