Abstract：
:In order to study the ocular dominance and responsiveness of cells in the deafferented visual cortex, the geniculate and the callosal inputs were interrupted in adult cats by either simultaneous (OTCCX) or separate surgical transection of the optic tract (OTX) and the posterior corpus callosum (CCX). Unit recording was chronically carried out mainly in the boundary of areas 17-18, the callosal projection zone. A small proportion of visually responsive cells was encountered in the deafferented hemisphere of the OTCCX (8.3%) and the OTX (6.3%) cats. In the intact hemisphere, 59.7% of the cells were visually responsive in the OTCCX cats and 57.0% in the OTX cats; they were 61.6% of the cells in the CCX cats and 85.6% in the normal controls (both hemispheres). The majority of the cells in the deafferented hemisphere of the OTCCX (88.9%) and the OTX (82.4%) cats were binocularly driven. In the intact hemisphere of the OTCCX cats, 85.1% of the cells were binocularly driven, in comparison to 77.6% in the OTX cats, 48.8% in the CCX cats, and 81.5% in the normal controls. We therefore concluded that following unilateral elimination of the geniculate input as well as the callosal transection, binocularity in the intact hemisphere was preserved despite the remarkable diminution in the responsiveness level there. Furthermore, the supply of visual input to the deafferented hemisphere was not affected after callosotomy, suggesting an alternative transfer, albeit minor, via an anterior callosal or another commissural pathway.
journal_name
Exp Neuroljournal_title
Experimental neurologyauthors
Yinon U,Achiron Adoi
10.1016/0014-4886(88)90174-4subject
Has Abstractpub_date
1988-03-01 00:00:00pages
579-88issue
3eissn
0014-4886issn
1090-2430journal_volume
99pub_type
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journal_title：Experimental neurology
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journal_title：Experimental neurology
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journal_title：Experimental neurology
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journal_title：Experimental neurology
pub_type： 杂志文章
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更新日期：2010-05-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2020.113524
更新日期：2021-02-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/0014-4886(83)90159-0
更新日期：1983-07-01 00:00:00
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journal_title：Experimental neurology
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doi：10.1016/j.expneurol.2005.08.020
更新日期：2005-12-01 00:00:00
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更新日期：2014-03-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章,评审
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更新日期：2006-09-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1006/exnr.2001.7854
更新日期：2002-03-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
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更新日期：1987-11-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2011.04.010
更新日期：2011-07-01 00:00:00
abstract：:In human diabetes, degenerative and functional disorders of the central nervous system, including depression, are common findings. Defective dentate gyrus (DG) neurogenesis is associated with affective-related disorders and depression. We previously demonstrated reduced DG neurogenesis in a pharmacological type 1 diab...
journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2007.11.009
更新日期：2008-04-01 00:00:00
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journal_title：Experimental neurology
pub_type： 杂志文章
doi：10.1016/j.expneurol.2008.04.005
更新日期：2008-07-01 00:00:00
