Abstract:
:In duodenal ulceration the Alcian blue staining acid mucosubstances in goblet cells are reduced and the goblet cells themselves disappear. At the same time periodic acid-Schiff (PAS) staining neutral mucosubstances appear in the cells of the surface epithelium. These changes have been measured quantitatively with the help of a Vickers M86/0010 Scanning and Integrated Microdensitometer. During healing the changes are reversed. It is suggested that these changes suggest a metaplasia towards a gastric type mucosa as a protective response to the presence of ulceration.
journal_name
Gutjournal_title
Gutauthors
Morrissey SM,Ward PM,Jayaraj AP,Tovey FI,Clark CGdoi
10.1136/gut.24.10.909subject
Has Abstractpub_date
1983-10-01 00:00:00pages
909-13issue
10eissn
0017-5749issn
1468-3288journal_volume
24pub_type
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