[Comparison of the acetylcholine receptor antibody titer and clinical course in neonatal myasthenia].

abstract：:We identified betulinic acid (BetA) as a new cytotoxic agent active against neuroectodermal tumor cells including neuroblastoma, medulloblastoma, glioblastoma and Ewing's sarcoma cells representing the most common solid tumors of childhood. BetA induced apoptosis independent of wild-type p53 protein and accumulation o...

journal_title：Klinische Padiatrie

authors： Fulda S,Jeremias I,Pietsch T,Debatin KM

更新日期：1999-07-01 00:00:00

abstract：:16 patients of studies AML-BFM-83 and -87 with allogeneic bone marrow transplantation (BMT) in first complete remission (CR) were compared with matched controls with postremission chemotherapy (CT-MC). CT-MC were selected from 250 non-grafted patients with a minimum of remission duration corresponding to the median in...

journal_title：Klinische Padiatrie

authors： Creutzig U,Bender-Götze C,Klingebiel T,Ebell W,Friedrich W,Stollmann-Gibbels B,Schmidt H,Suttorp M,Gratwohl A,Heyen P

更新日期：1992-07-01 00:00:00

abstract：:Purpose To determine the population prevalence and risk factors of myopia in children and adolescents in Germany. Methods The prevalence of myopia in Germany was computed using data from the 2003-2006 German Health Interview and Examination Survey for Children and Adolescents (N=17 640, 49% girls). Status of myopia wa...

journal_title：Klinische Padiatrie

authors： Schuster AK,Elflein HM,Pokora R,Urschitz MS

更新日期：2017-07-01 00:00:00

abstract：:The therapy of complicated Kaposiform hemangioendothelioma (KHE) is still difficult. We present the first case of laryngomalacia with simultaneous mammalian target of Rapamycin (mTOR)-positive KHE of the neck and thoracic inlet and concurrent Kasabach-Meritt Phenomenon (KMP) in an 11-month-old boy suffering life-threa...

journal_title：Klinische Padiatrie

authors： Schroeder U,Lauten M,Stichtenoth G,Gebhard MP,Buchholz M,Kaiser MM

更新日期：2014-11-01 00:00:00

abstract：:The synchronous occurrence of blasts of the lymphatic and myelogenous lineage in acute leukemia has been rarely observed. Reviewing individual case reports it is suggested that malignant transformation already starts at the level of the stem cell. We are reporting a case of a 13-year old boy who initially showed morph...

journal_title：Klinische Padiatrie

authors： Creutzig U,Eschenbach C,Ritter J,Schellong G

更新日期：1981-05-01 00:00:00

abstract：:Tumors of the central nervous system account for 15.7% of all malignancies registered at the documentation center for childhood malignancies in Western Germany. This group constitutes the largest entity of solid tumors. With the exception of medulloblastoma the five-year survival probability of children with cns tumor...

journal_title：Klinische Padiatrie

authors： Kühl J

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Intrauterine growth restriction seems to be a risk factor for an aggravated course of secondary renal diseases in children. Catch-up growth after birth may play a critical role. We tested if there is an association between an aggravated course of nephritis in Henoch-Schönlein Purpura (PSHN) and low birth wei...

journal_title：Klinische Padiatrie

authors： Plank C,Vasilache I,Dittrich K,Dötsch J

更新日期：2010-12-01 00:00:00

abstract：:The article reports on the case history of a 8 month old baby who fell ill of a ileocolic intussusception. The barium enema demonstrated the typical cupping in the head of the barium. The successful reposition by hydrostatic pressure was manifest by barium reflux in the small intestine. ...

journal_title：Klinische Padiatrie

authors： Klingmüller V

更新日期：1983-07-01 00:00:00

abstract：:Aim of this study was to describe the course of perinatal factors in neonates with meconium aspiration syndrome (MAS) from 1990 to 2010 and to determine risk factors for a severe course of the disease.All neonates with MAS hospitalized in our level III neonatal intensive care unit from 1990 to 2010.Retrospective analy...

journal_title：Klinische Padiatrie

authors： Hofer N,Jank K,Resch E,Urlesberger B,Reiterer F,Resch B

更新日期：2013-12-01 00:00:00

abstract：:In 24 patients at risk for SIDS (12 infants with a near miss event and 12 infants with apnea and perioral cyanosis during sleep) respiratory and esophageal function were investigated by impedance pneumography (IP) and esophageal manometry combined with simultaneous pH-monitoring (EMPH). Both groups had ad early pathol...

journal_title：Klinische Padiatrie

authors： Landler U,Höllwarth ME,Uray E,Schober PH,Reiterer F,Schenkeli R

更新日期：1990-01-01 00:00:00

abstract：:The control of severe infectious complications by preventive strategies, early diagnosis of infections and empiric broad-spectrum antibiotic therapy contributed to a marked improvement of survival in children with cancer over the last 20 years. This article overviews of the importance of prevention of infectious compl...

journal_title：Klinische Padiatrie

authors： Fleischhack G,Simon A

更新日期：2001-09-01 00:00:00

abstract：:The selective uptake and accumulation of 131J-Metaiodobenzylguanidine in neuroblastoma cells in vivo may be utilized for targeted irradiation. The experience with 32 neuroblastoma patients refractory to conventional high dose chemotherapy is reported. At diagnosis 8 patients had Evans stage III and 22 stage IV. 11/32 ...

journal_title：Klinische Padiatrie

authors： Berthold F,Feine U,Fischer M,Gerein V,Klingebiel T,Maul FD,Waters W,Wehinger H,Treuner J

更新日期：1988-05-01 00:00:00

abstract：:The clinical significance of colloid osmotic pressure (COP) in transcapillary fluid exchange and water homeostasis in health and disease is described. Under pathophysiological circumstances measurement of COP should be preferred to COP value calculation. After extensive COP experiences in critically ill adults and num...

journal_title：Klinische Padiatrie

authors： Abel M

更新日期：1985-09-01 00:00:00

abstract：OBJECTIVES:Despite about 3 decades of clinical experience with the therapy of inherited thrombocytopathies (HTP) with desmopressin (DDAVP) the mechanisms of haemostatic effects of DDAVP in these diseases remain unclear. Therefore platelet function diagnostics was carried out in whole blood (WB) from children with aspir...

journal_title：Klinische Padiatrie

authors： Tauer JT,Gneuss A,Lohse JE,Jürgens T,Knöfler R

更新日期：2011-05-01 00:00:00

abstract：:Between 1981 and 2000, 6 609 children (<18 years of age) were treated in 5 consecutive trials of the Berlin-Frankfurt-Münster (BFM) study group for childhood acute lymphoblastic leukemia (ALL). Patients were treated in up to 82 centers in Germany, Austria, and Switzerland. Probability of 10-year event-free survival (s...

journal_title：Klinische Padiatrie

authors： Schrappe M,Möricke A,Reiter A,Henze G,Welte K,Gadner H,Ludwig WD,Ritter J,Harbott J,Mann G,Klingebiel T,Gruhn B,Niemeyer C,Kremens B,Niggli F,Debatin KM,Ratei R,Stanulla M,Beier R,Cario G,Schrauder A,Zimmermann

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Sonographic screening helps to discover pathological findings in asymptomatic patients. In these cases the decision about diagnostic and therapeutic consequences is difficult. CASE REPORT:We describe a girl with a congenital small solitary hepatic cyst with rapidly increasing size after the second year, whi...

journal_title：Klinische Padiatrie

authors： Reichel S,Alzen G,Keller KM,Weitzel D

更新日期：2002-11-01 00:00:00

abstract：:Autoimmune hemolytic anaemia (AIHA) in childhood is associated with antibodies produced by the patient himself, which coat his red cells causing their hemolysis. Although in some cases no underlying disease could be found, in the majority of children a virus etiology is apparent. There are very few reports regarding t...

journal_title：Klinische Padiatrie

authors： Haas RJ,Pöschl U,Christ M,Schaub J,Belohradsky BH

更新日期：1977-05-01 00:00:00

abstract：BACKGROUND:Vaccination with 2 doses of > 95% of the population is necessary to eliminate measles. In Switzerland and especially in the central part, vaccine coverage is low (2006: 65%). This led 2006-2009 to a measles epidemic with thousands of cases and high costs. One death was noted in a formerly healthy 12 year old...

journal_title：Klinische Padiatrie

authors： Donas A,Marty-Nussbaumer A,Roost HP,Neuhaus TJ

更新日期：2014-01-01 00:00:00

abstract：:Wegener's granulomatosis is together with Churg-Strauss syndrome and microscopic polyangiitis a very rare cause of hemoptysis in childhood. We report on a 14 years old girl who developed arthralgia, purpura, glomerulonephritis and a diffuse alveolar haemorrhage with hemoptysis after a short time period of unspecific s...

journal_title：Klinische Padiatrie

authors： Heckmann M,Weber K,Reineck P,Schüler D,Geidel C,Steiss JO

更新日期：2006-01-01 00:00:00

abstract：:Evoked otoacoustic emissions (EOAE) and brainstem acoustic evoked potentials (BAEP) were recorded from 78 children following neonatal intensive care. In 23% no EOAE could be obtained. Hearing impairment in the BAEP was found in 9%. In 22% negative EOAE were found in spite of normal BAEP. According to the latency-inten...

journal_title：Klinische Padiatrie

authors： Lauffer H,Pröschel U,Gerling S,Wenzel D

更新日期：1994-03-01 00:00:00

abstract：:The paper reported about septicaemia in the neonatal and infant period. Continuing former investigations by Kienitz in the same pediatric clinic we have got a survey from 1933 to 1974. In the last years we saw increasingly more infections with gram-negative organisms, especially by Pyocyaneus with a severe prognosis. ...

journal_title：Klinische Padiatrie

authors： Diekmann L,Kotzur J

更新日期：1976-03-01 00:00:00

abstract：:We present three cases of GC, one belonging to the brainstem, and two belonging to the hemisphere type. Two cases were investigated by MRI. Tumour infiltration, while yielding only vague CT findings, was well demonstrated in MR studies where extensive hyperintense lesions were found in T2- and proton density images. I...

journal_title：Klinische Padiatrie

authors： Borgis KJ,Larsen JL,Mørk S,Brückmann H

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Supraventricular reentrant tachycardias are the most common cardiac arrhythmia observed in infancy and childhood. The often benign clinical course of the disease warrants careful selection of any antiarrhythmic drug given to prevent recurrencies, in order to avoid potentially dangerous side-effects such as p...

journal_title：Klinische Padiatrie

authors： Pfammatter JP,Weber JW,Stocker FP

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Thyroglossal duct cysts arise from mucus production in an incomplete regressed thyroglossal duct. Often they are only noticed in case of infection or secondary fistulation. The operative management is a Sistrunk procedure. METHOD AND PATIENTS:In a retrospective study we analyse 26 patients aged 0,3 - 10 yea...

journal_title：Klinische Padiatrie

authors： von Bismarck S,Höllwarth ME

更新日期：2001-09-01 00:00:00

abstract：:In a randomised study the efficacy of a cytomegalic hyperimmune globulin preparation (CMV-HIGP) which had been treated with beta-propiolactone was analysed. The study included 85 patients with acute lymphoblastic leukemia (ALL) and Non-B-Non-Hodgkin-lymphoma (NHL) who were treated initially or underwent a relapse ther...

journal_title：Klinische Padiatrie

authors： Gerein V,Kropp H,Schwabe D,Gussetis E,Langer B,Kornhuber B

更新日期：1989-07-01 00:00:00

abstract：:The integration of colleagues from psychosocial occupations into the traditional team of doctors and nurses demands a holistic treatment concept, the general desire for interdisciplinary action, and readiness for patience in the process of mutual learning. The acceptance of the psychosocial services by the patient and...

journal_title：Klinische Padiatrie

authors： Janssen F

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Up to now, reliable data has not been available on the actual costs of treating oncological patients. However, such data material is urgently required in view of the institution of the health service reform with the concomitant introduction of the G-DRG remuneration system. PATIENTS:The medical services and...

journal_title：Klinische Padiatrie

authors： Stäbler W,Wagner B

更新日期：2003-05-01 00:00:00

abstract：:The GPOH-MAHO trials designed in 3/82 and 7/88 for treatment of childhood testicular germ cell tumors registered 3/92 105 pts. In MAHO 82 study 57 pts. and in MAHO 88 study 48 pts. were treated. Histologically 60% of the tumors revealed yolk sac tumors (YST), 22% teratomas (TD) and 18% malignant teratomas (MTI, MTU, M...

journal_title：Klinische Padiatrie

authors： Haas RJ,Schmidt P,Göbel U,Harms D

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:Autism spectrum disorders (ASDs) are a group of developmental disabilities in childhood and adolescence. Beside genetic predisposition also environmental influences may contribute to the ASD pathogenesis. Family members of children and adolescents with ASD often ask for specific diets to alleviate ASD-associ...

journal_title：Klinische Padiatrie

authors： Sausmikat J,Smollich M

更新日期：2016-03-01 00:00:00

abstract：:Report on a case of acute childhood leukemia, who presents with the following exceptional features: During complete remission early bilateral leukemic infiltrations of the testes, followed--after an intervall of several months--by a serve, general relapse with ascites. New induction therapy resulted in a second comple...

journal_title：Klinische Padiatrie

authors： Hansen HG,Graucob E

更新日期：1979-01-01 00:00:00