Meconium aspiration syndrome--a 21-years' experience from a tertiary care center and analysis of risk factors for predicting disease severity.

abstract：BACKGROUND:Intracellular antibodies (intrabodies) have been used for the generation of phenotypic knockouts in vivo by surface depletion of extracellular or transmembrane proteins. Intrabodies present an alternative to methods of gene inactivation that target genomic DNA or m-RNA, such as RNA interference. Several stud...

journal_title：Klinische Padiatrie

authors： Jendreyko N,Rader C,Barbas CF 3rd,Gaedicke G

更新日期：2006-05-01 00:00:00

abstract：:During the last 6 years 73 previously untreated children and adolescents with acute lymphoblastic leukemia were enrolled on a non-randomized therapy protocol. In this longitudinal study the specific accent was put on the intensified induction treatment of 8 weeks' duration which was thought to achieve a higher remissi...

journal_title：Klinische Padiatrie

authors： Riehm H,Gadner H,Welte K

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:Neurotrophins and their cognate receptors TrkA, TrkB and TrkC regulate proliferation, differentiation and death of neuronal progenitor cells and may be implicated in the progression of medulloblastoma and other primitive neuroectodermal brain tumors (PNET). These common childhood brain tumors are composed of...

journal_title：Klinische Padiatrie

authors： Grotzer MA,Janss AJ,Phillips PC,Trojanowski JQ

更新日期：2000-07-01 00:00:00

abstract：:Inherited disorders of platelets constitute a group of rare diseases that give rise to bleeding syndromes of variety severity, with more severe cases being first diagnosed during infancy and childhood. To appropriate diagnose a platelet function disorder during early childhood the knowledge of the physiological charac...

journal_title：Klinische Padiatrie

authors： Schlegel N,Bardet V,Kenet G,Muntean W,Zieger B,Nowak-Göttl U,Working Group on Standardisation in Perinatal and Pediatric Hemostasis.

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Modern neonatal and pediatric intensive care includes a sophisticated pharmacotherapy with numerous drugs, mainly administered intravenously. Often, despite the use of multi-lumen central venous lines, more peripheral venous accesses are required. To reduce the necessity of numerous venous lines on one hand ...

journal_title：Klinische Padiatrie

authors： Höpner JH,Schulte A,Thiessen J,Knuf M,Huth RG

更新日期：2007-01-01 00:00:00

abstract：:Doxorubicin serum levels were measured with a highly specific reversed-phase HPLC-method in patients undergoing combination chemotherapy. Serum elimination kinetics of doxorubicin follow a bi- or triphasic first order pattern with a high interpatient variability. T 1/2 of the first distribution phase was 5.4 min. T 1/...

journal_title：Klinische Padiatrie

authors： Erttmann R,Grandt M,Erb N,Garbrecht M,Landbeck G

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Sonographic screening helps to discover pathological findings in asymptomatic patients. In these cases the decision about diagnostic and therapeutic consequences is difficult. CASE REPORT:We describe a girl with a congenital small solitary hepatic cyst with rapidly increasing size after the second year, whi...

journal_title：Klinische Padiatrie

authors： Reichel S,Alzen G,Keller KM,Weitzel D

更新日期：2002-11-01 00:00:00

abstract：:Since 1980, a growing number of pediatric patients with mutism following posterior fossa surgery have been recognized. This syndrome typically affects children and in rare cases young adults who become mute one or two days after tumor operation but do not show disturbances of consciousness or language comprehension. T...

journal_title：Klinische Padiatrie

authors： Janssen G,Messing-Jünger AM,Engelbrecht V,Göbel U,Bock WJ,Lenard HG

更新日期：1998-07-01 00:00:00

abstract：:This is a report of the neonatal form of nonketotic hyperglycinemia with rapid progressing neurological symptoms, respiratory distress and seizures. The EEG pattern is characteristic, the ratio of cerebrospinal fluid to plasma glycine abnormally high. The result of cranial computerized tomography demonstrates also in ...

journal_title：Klinische Padiatrie

authors： Plöchl E,Rittinger O,Doringer E,Laubichler W

更新日期：1991-11-01 00:00:00

abstract：:Positive anti-DNA-antibodies and lowered C3 and C4 levels were found in serum of a 13 year old girl presenting with edema, microscopic hematuria and proteinuria. Renal biopsy revealed diffuse endo- and extracapillary glomerulonephritis with mesangial deposits of IgA, IgG, IgM, C1q, C3 and fibrinogen. In spite of treat...

journal_title：Klinische Padiatrie

authors： Michalk D,Scharf J,Waldherr R

更新日期：1983-11-01 00:00:00

abstract：:The paper reported about septicaemia in the neonatal and infant period. Continuing former investigations by Kienitz in the same pediatric clinic we have got a survey from 1933 to 1974. In the last years we saw increasingly more infections with gram-negative organisms, especially by Pyocyaneus with a severe prognosis. ...

journal_title：Klinische Padiatrie

authors： Diekmann L,Kotzur J

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Due to rising survival rates in cancer and autoimmune diseases fertility preservation before gonadotoxic therapies has become increasingly important. Although fertility can be significantly affected by gonadotoxic therapies, the possibility of fertility preservation during childhood has not been sufficiently...

journal_title：Klinische Padiatrie

authors： Sänger N,Jarisch A,Ochsendorf F,Klingebiel T,Liebenthron J,Kliesch S,von Wolff M

更新日期：2018-02-08 00:00:00

abstract：:While many aspects related to the etiology and pathogenesis of sudden infant death remain unclear, the ultimate trigger event appears to be an acute regulatory disturbance of the cardiorespiratory neurons of the reticular formation of the brain stem. Retrospective studies have demonstrated that SIDS often occurs after...

journal_title：Klinische Padiatrie

authors： Sterniste W,Bock W

更新日期：1992-03-01 00:00:00

abstract：:Evoked otoacoustic emissions (EOAE) and brainstem acoustic evoked potentials (BAEP) were recorded from 78 children following neonatal intensive care. In 23% no EOAE could be obtained. Hearing impairment in the BAEP was found in 9%. In 22% negative EOAE were found in spite of normal BAEP. According to the latency-inten...

journal_title：Klinische Padiatrie

authors： Lauffer H,Pröschel U,Gerling S,Wenzel D

更新日期：1994-03-01 00:00:00

abstract：:In 24 patients at risk for SIDS (12 infants with a near miss event and 12 infants with apnea and perioral cyanosis during sleep) respiratory and esophageal function were investigated by impedance pneumography (IP) and esophageal manometry combined with simultaneous pH-monitoring (EMPH). Both groups had ad early pathol...

journal_title：Klinische Padiatrie

authors： Landler U,Höllwarth ME,Uray E,Schober PH,Reiterer F,Schenkeli R

更新日期：1990-01-01 00:00:00

abstract：:A case of an infant with a mediastinal neurenteric cyst is used to review this rare entity. By definition a neurenteric cyst is the combination of an entodermal cyst with a vertebral dysplasia. Neurenteric cysts are located in the posterior mediastinum, preferentially on the right side. In a third of the patients thes...

journal_title：Klinische Padiatrie

authors： Köster B,Emons D,Kunath U,Födisch HJ

更新日期：1987-01-01 00:00:00

abstract：:Since reliable diagnosis of cystic fibrosis (CF) is still difficult, the occurrence of serum markers CA 19-9, CA 50 and elastase 1 was analysed. Serum levels of CA 19-9, CA 50, CA 125 and elastase 1 were estimated in 54 CF patients as well as in a control group of 66 children of similar age suffering from various othe...

journal_title：Klinische Padiatrie

authors： Uhlenbruck G,Scheuring U,Dienst C,Kaiser D,Roth B,Skopnik H

更新日期：1988-03-01 00:00:00

abstract：BACKGROUND:Burning pain of red and warm hands and/or feet are the classical symptoms of erythromelalgia. CASE REPORT:We describe the symptoms of acute idiopathic erythromelalgia and arterial hypertension in a five-year-old boy. Five days after a gastroenteritis the patient developed burning hands and feet in combinati...

journal_title：Klinische Padiatrie

authors： Zenz W,Zöhrer B,Zobel G,Schulze-Bauer C

更新日期：1999-11-01 00:00:00

abstract：:Longitudinal growth was assessed in 10 children aged 0.8 to 11.8 years with adrenocortical tumors. All children had signs of androgen excess. In addition, 5 children had glucocorticoid excess, 1 child had estrogen excess. Multiple height recordings, expressed as height standard deviation score for chronological age, w...

journal_title：Klinische Padiatrie

authors： Hauffa BP,Roll C,Mühlenberg R,Havers W

更新日期：1991-03-01 00:00:00

abstract：:Background: Transient synovitis is the most common hip joint disorder in children. Perthes disease occurs around the same age and may not be distinguishable to an episode of transient synovitis in the early stage. Therefore all children in our clinic with transient synovitis underwent a follow-up X-ray 3 months later ...

journal_title：Klinische Padiatrie

authors： Lenoir U,Slongo T,Aghayev E,Joeris A

更新日期：2017-03-01 00:00:00

abstract：:We analyzed episodes of peritonitis and/or sepsis associated with the idiopathic nephrotic syndrome (ns) in 23 children treated between 1975 and 1985 at our clinic. 37.5% of the children with infantile ns, 16% of those with steroidsensible ns, and 13.6% of those with steroidresistant ns developed peritonitis. Children...

journal_title：Klinische Padiatrie

authors： Feldhoff C,Kleine L,Bachmann H

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:It has been shown that Interleukin 10 (IL-10) is able to inhibit alloreactivity in a mixed lymphocyte culture. Therefore, here IL-10 production in patients after allogeneic BMT was investigated and correlated with the incidence of acute GvHD. PATIENTS:14 patients after allogeneic BMT have been investigated....

journal_title：Klinische Padiatrie

authors： Körholz D,Hempel L,Packeisen J,Kunst D,Zintl F,Burdach S

更新日期：1996-07-01 00:00:00

abstract：:The synchronous occurrence of blasts of the lymphatic and myelogenous lineage in acute leukemia has been rarely observed. Reviewing individual case reports it is suggested that malignant transformation already starts at the level of the stem cell. We are reporting a case of a 13-year old boy who initially showed morph...

journal_title：Klinische Padiatrie

authors： Creutzig U,Eschenbach C,Ritter J,Schellong G

更新日期：1981-05-01 00:00:00

abstract：:According to the theories of Schachter concerning the external response of obese adults, which have been confirmed by Jung, Pudel and Nisbett, we tested these theories in obese adolescents. Eating behaviour of 16 grossly obese adolescents (8 males, 8 females, mean age 13.2 +/- 0.3 years, mean relative body weight 124 ...

journal_title：Klinische Padiatrie

authors： Widhalm K,Zwiauer K,Eckharter I

更新日期：1990-05-01 00:00:00

abstract：:Bacteriologic cultures of the vagina and the cervix of 38 praepubertal children, aged 3 months to 16 years (average age 9 years) from the outpatient department for infants and juveniles of the 1st Department of Obstetrics and Gynecology of the University of Vienna were obtained vaginascopically using anaerobic transpo...

journal_title：Klinische Padiatrie

authors： Gerstner G,Boschitsch E,Grünberger W,Rotter M

更新日期：1982-01-01 00:00:00

abstract：:Hepatotoxicity of valproic acid (VPA) is reported in a psychomotor retarded boy. A four-month antiepileptic therapy was followed by a combined VPA/phenytoin treatment where-upon, two months later, the patient died in a hepatic coma. In the final state the metabolic pattern of VPA was still found within the normal rang...

journal_title：Klinische Padiatrie

authors： Keulen FP,Kochen W

更新日期：1985-09-01 00:00:00

abstract：:A HPLC-method is described to determine the Pseudouridine/creatinine ratio in spontaneous urine samples in infancy and childhood. The urines of 74 healthy children between 1 and 18 years of age and of 231 children with different diseases were examined for this ratio, making 1097 measurements. 157 children suffered fro...

journal_title：Klinische Padiatrie

authors： Graf N,Bach K,Frisch B,Haas HJ,Sitzmann FC

更新日期：1989-05-01 00:00:00

abstract：:Interdisciplinary cooperation and networking determine the success of activities for supporting families at risk for early childhood abuse. The integration of the healthcare sector might be important.The medical standard of perinatal care at the University hospital includes information exchange about family risk facto...

journal_title：Klinische Padiatrie

authors： Clauß D,Deutsch J,Krol I,Haase R,Willard P,Müller-Bahlke T,Mauz-Körholz C,Körholz D

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:The prevalence of asthma and overweight/obesity in children and adolescents is continuously increasing over the last decades. It remains unclear if overweight/obesity raises the risk of developing asthma or if an uncontrolled asthma increases the risk of developing overweight/obesity by restricting physical ...

journal_title：Klinische Padiatrie

authors： Schmauck-Gómez JS,Menrath I,Kaiser MM,Herz A,Kopp MV

更新日期：2016-07-01 00:00:00

abstract：:Concentrations of free thyroxine (n = 341, male = 205, female = 136) and free triiodothyronine (n = 318, male = 198, female = 120) were determined using the radioimmunoassay method in blood serum of euthyroid children. Beyond the 30. day of life no significant differences were found in different age groups for the fre...

journal_title：Klinische Padiatrie

authors： Liappis N,Starke A

更新日期：1987-09-01 00:00:00