Abstract：
:Since 1980, a growing number of pediatric patients with mutism following posterior fossa surgery have been recognized. This syndrome typically affects children and in rare cases young adults who become mute one or two days after tumor operation but do not show disturbances of consciousness or language comprehension. The disorder persists for 1 to 4 months. The pathogenesis is still unknown. Of 21 children who underwent surgery for large posterior fossa tumors between 1991 and 1995, 6 developed cerebellar mutism. Histologically the tumors were classified as astrocytoma WHO grade I, astrocytoma WHO grade II and ependymoma WHO grade III in one case and medulloblastoma WHO grade IV in three cases. Besides the clinical course, intraoperative findings and CT or MRI data are evaluated and discussed considering possible etiological hypotheses. Our own experience and also literature reviews suggest that the lesion of the cerebellar hemispheres might be the most important one of multiple factors causing cerebellar mutism. Generally the syndrome is transient. The diagnosis should not delay adjuvant therapy in patients with a malignancy.
journal_name
Klin Padiatrjournal_title
Klinische Padiatrieauthors
Janssen G,Messing-Jünger AM,Engelbrecht V,Göbel U,Bock WJ,Lenard HGdoi
10.1055/s-2008-1043886subject
Has Abstractpub_date
1998-07-01 00:00:00pages
243-7issue
4eissn
0300-8630issn
1439-3824journal_volume
210pub_type
杂志文章abstract：:The secretory IgA system is common to all mucosal membranes and is presumably of great importance for their defense. In addition to the secretory IgA antibodies produced in a mucosa in response to a local antigenic stimulus there is a spread of this type of IgA response via committed lymphocytes. They originate from c...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2008-1033997
更新日期：1985-07-01 00:00:00
abstract：:Infectious heart diseases in childhood are--with less than 1% of hospital admissions--rare, but serious diseases. Among several causes of myocarditis in our region virus myocarditis plays the most important role. Besides of the acute course an autoimmune mediated chronic myocarditis and the transition to dilated cardi...
journal_title：Klinische Padiatrie
pub_type： 杂志文章,评审
doi：10.1055/s-2007-1025390
更新日期：1991-01-01 00:00:00
abstract：:The long term follow up of 55 children with allergy treated by specific hyposensitization therapy is reported. Hyposensitization therapy had been terminated from 2--7 years previously. The success of treatment was subjectively judged to be satisfactory of good in 62% of the cases. In the group of asthmatic children, a...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：
更新日期：1975-11-01 00:00:00
abstract：:Background: Diabetes mellitus is a common endocrinopathy in patients with thalassemia major, but the occurrence of hemoglobinopathies is rare in Germany and Western Europe. The longitudinal German-Austrian DPV (Diabetes Patienten Verlaufsdokumentation) registry allows a comprehensive characterization of this group of ...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-0042-111691
更新日期：2016-11-01 00:00:00
abstract：:A congenital diverticulum of the ventricle is a very rare cardiac lesion which is almost always associated with additional cardiovascular anomalies. In the majority of cases a diverticulum of the heart has been diagnosed during cardiac catheterization for evaluation of additional cardiovascular anomalies. We report no...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2007-1025221
更新日期：1993-05-01 00:00:00
abstract：:Neurological symptoms developed in a girl aged three-and-a-half years during treatment with nalidixic acid. The symptoms progressed even after the preparation had been discontinued, and culminated in the development of a transient intracranial pressure increase. ...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：
更新日期：1979-07-01 00:00:00
abstract：:Severe anaphylactic reactions were observed in 2 children, aged 2 and 14 years, with acute lymphocytic leukemia and a 12 month old infant with a functional T-cell defect after intravenous administration of a polyethyleneglycol (PEG)-treated immunoglobulin preparation. All 3 children suffered additionally from hypogamm...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2008-1026802
更新日期：1987-07-01 00:00:00
abstract：:Neurofibromatosis type 1 is the most common of the phakomatoses and the clinical follow-up is an interdisciplinary challenge. The data of 27 patients with NF1 were systematically reviewed and compared to data from the literature. All of our patients had clinical signs of NF1. Besides the classic criteria café-au-lait ...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2007-973086
更新日期：2007-11-01 00:00:00
abstract：:In case of painful scoliosis, a search for etiologic factors in the vertebral spinal canal and adjacent structures should be made. MRI with Gadolinium is useful to look for various pathology in and around the spine in particular of spinal cord. CT scanning is indispensible for bony details. Thus CT and MRI are complem...
journal_title：Klinische Padiatrie
pub_type： 杂志文章,评审
doi：10.1055/s-2008-1043932
更新日期：1997-03-01 00:00:00
abstract：:Possibilities of recognizing cerebral function disturbances in newborns as early as the acute phase of the condition, and of prognosticating permanent brain damage are described. Clinical findings such as lethargy or spasms in the second and third weeks of life following hypoxia indicate severe function disturbances w...
journal_title：Klinische Padiatrie
pub_type： 杂志文章,评审
doi：10.1055/s-2008-1034092
更新日期：1984-11-01 00:00:00
abstract：OBJECTIVE:To identify obstetric and neonatal risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) in high-risk preterm neonates. METHODS AND PATIENTS:Data from 279 preterm infants (246 mothers) with a gestational age≤28+0 weeks admitted to our NICU between January 2004 a...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-0042-111689
更新日期：2016-09-01 00:00:00
abstract：:Polycythemia vera - the most frequent form of a primary erythrocytosis in adult patients - represents an extremely rare disease in pediatric and juvenile patients as do congenital primary and secondary erythrocytoses. Frequently, in patients with these diseases clinical problems do not occur before adulthood. Systemat...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2004-822628
更新日期：2004-05-01 00:00:00
abstract：:Interferons are components of the nonspecific defense system. Their most prominent biological roles are the antiviral, the antiproliferative, and the immunoregulatory activities. However, their primary functions within the organism remains to be determined. Three types of IFNs have been described so far (IFN alpha, IF...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2008-1033980
更新日期：1985-07-01 00:00:00
abstract：OBJECTIVE:To investigate the change of psychological symptoms and quality of life in children and adolescents with congenital heart disease, cancer, or cystic fibrosis after a family-oriented inpatient rehabilitation program. METHODS:302 participants in the intervention (aged 4-17 years, mean=8.7) were assessed using ...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-0030-1262831
更新日期：2011-03-01 00:00:00
abstract：:Centralized treatment of critically ill pediatric patients and related problems are presented. Pediatric intensive care allows to overbridge deranged or interrupted organ functions while simultaneously treating the disease causing the disturbance. Its efficiency depends on continuity of medical care. Medical and nursi...
journal_title：Klinische Padiatrie
pub_type： 杂志文章,评审
doi：10.1055/s-2008-1035616
更新日期：1980-09-01 00:00:00
abstract：:630 neonates with risk factors of perinatal hearing impairment were screened of hearing loss by means of registration of transient otoacoustic emissions before discharge from the newborn nursery. Neonates were screened additionally by means of brainstem evoked response audiometry, if they had bilateral negative emissi...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2008-1043853
更新日期：1998-03-01 00:00:00
abstract：:The present clinical observation is related to a 14-year-old girl suffering from acute myeloid leukemia. The clinical course was complicated by episodes of severe enterocolitis, E. coli- septicemia, pancreatitis and pneumonia. In the course of continued cytostatic and antibiotic treatment a persistent asymptomatic Lac...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2008-1043764
更新日期：1999-03-01 00:00:00
abstract：:The observation of constitutional chromosome abnormalities in a one and half year old boy with Wiedemann-Beckwith syndrome (WBS) and hepatoblastoma prompted us to review the currently available literature dealing with this subject. In approximately 500 published cases with complete and incomplete forms of WBS, 42 mali...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2008-1026804
更新日期：1987-07-01 00:00:00
abstract：:A case of true hermaphroditism was described. The patient had an uterus, a fallopian tube, a testide on the left in the position of the ovary and an ovary on the right side. The chromosome picture corresponded to a 47, XXY/46, XX/46 XXY mosaic. The phenotype of the patient was male so the decision for male sex seemed ...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：
更新日期：1976-09-01 00:00:00
abstract：:Immunological responses are divided into those mediated by humoral antibody (B-Cells) and those by cells (T-Cells). Both depend upon the activity of small lymphocytes which become thymus or bursa analogue dependent during embryonic development. Primary immundeficiencies are therefor defects of lymphocytes attributed i...
journal_title：Klinische Padiatrie
pub_type： 杂志文章,评审
doi：
更新日期：1975-11-01 00:00:00
abstract：:The paper reported about septicaemia in the neonatal and infant period. Continuing former investigations by Kienitz in the same pediatric clinic we have got a survey from 1933 to 1974. In the last years we saw increasingly more infections with gram-negative organisms, especially by Pyocyaneus with a severe prognosis. ...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：
更新日期：1976-03-01 00:00:00
abstract：BACKGROUND:Late effects become progressively more important for the evaluation of therapeutic success in paediatric oncology. Thus, in 1998, the Late Effects Surveillance System (LESS) started to register and assess multicentrally, prospectively and longitudinally late effects of treatment for the group of Ewing's, sof...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2005-836503
更新日期：2005-05-01 00:00:00
abstract：:In the present study the possibility of immunophenotyping of routinely prepared (air dried) peripheral blood and bone marrow smears is described after storage. The immunoenzymatical alkaline-phosphatase-anti-alkaline-phosphatase (APAAP)-method was carried out in differently stored blood smears (+4 degrees C and -80 de...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2007-1025311
更新日期：1989-07-01 00:00:00
abstract：:Analysis of the cellular DNA content was carried out in 162 children with ALL and 34 children with AML admitted to the university children's hospital Münster between 1979 and 1984. DNA aneuploidies were identified at a similar frequency in ALL (40%) and AML (44%). However, the degree of DNA aneuploidies (DNA-index) wa...
journal_title：Klinische Padiatrie
pub_type： 临床试验,杂志文章
doi：10.1055/s-2008-1033972
更新日期：1985-05-01 00:00:00
abstract：:The article reports on the case history of a 8 month old baby who fell ill of a ileocolic intussusception. The barium enema demonstrated the typical cupping in the head of the barium. The successful reposition by hydrostatic pressure was manifest by barium reflux in the small intestine. ...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2008-1034383
更新日期：1983-07-01 00:00:00
abstract：BACKGROUND:Thyroglossal duct cysts arise from mucus production in an incomplete regressed thyroglossal duct. Often they are only noticed in case of infection or secondary fistulation. The operative management is a Sistrunk procedure. METHOD AND PATIENTS:In a retrospective study we analyse 26 patients aged 0,3 - 10 yea...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2001-17223
更新日期：2001-09-01 00:00:00
abstract：:Mycobacterial infections are rarely reported in Cystic Fibrosis patients although they quite often develop predisposing risk factors such as underweight, secondary diabetes mellitus and chronic inflammatory pulmonary disease. Furthermore glucocorticoid therapy is mandatory in some patients. CF heterozygotes are said t...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2007-1025461
更新日期：1991-09-01 00:00:00
abstract：:Background For the new cystic fibrosis (CF) newborn screening program in Germany the Federal Joint Committee (G-BA) implemented a new screening protocol using immunoreactive trypsinogen (IRT) as first and pancreatitis associated protein (PAP) as second tier. Gene analysis with a panel of 31 CFTR-mutations is used as t...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-0042-124187
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Hypoallergenic infant formulas (HAF) were developed for atopy prevention in infants with high risk of atopy if these cannot be breastfed. HAF mount an antigen-specific immune response in infants. The aim of the study was to analyse the immune response in infants fed with a new infant formula based on a whey ...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/s-2003-42664
更新日期：2003-09-01 00:00:00
abstract：BACKGROUND:The medical care of pediatric cancer patients in the German health care system relies on special structures. All children and adolescents with a diagnosis of cancer receive uniform treatment within clinical studies or registers and exclusively at centers which can ensure interdisciplinary care by a multiprof...
journal_title：Klinische Padiatrie
pub_type： 杂志文章
doi：10.1055/a-1158-9341
更新日期：2020-11-01 00:00:00
