[DNA aneuploidy in children with acute leukemia: II. Correlation with the phenotype of blasts, clinical picture and course of disease].

abstract：:A report was made of three patients who exhibited pronounced heptosplenomegaly at the time of hospital admission: a six-year-old girl and two brothers, 1 year 4 months and 4 years 4 months of age. As is typical for Niemann-Pick disease, foam cells were found in the bone marrow and the liver biopsy specimens for the th...

journal_title：Klinische Padiatrie

authors： Priscu R,Pancu L,Balan A,Petrescu TC,Iacob C

更新日期：1977-11-01 00:00:00

abstract：:This report describes the case of a 10 days old newborn of a diabetic mother with gestosis, who developed erythema and swelling of the right cheek. A diagnosis of acute suppurative parotitis due to S. aureus was made. Following this case report the most important facts of epidemiology, pathogenesis, clinical manifesta...

journal_title：Klinische Padiatrie

authors： Möckel A,Nissler K,Wilhelm T,Handrick W

更新日期：2005-03-01 00:00:00

abstract：AIM:Reports describing coronavirus disease 2019 (Covid-19) in children are fewer than adult studies due to milder clinical picture. We aimed to share our experience at a single center with an emphasis on collective decision making. MATERIALS AND METHODS:A suspected case was defined as the presence of symptoms suggesti...

journal_title：Klinische Padiatrie

authors： Duramaz BB,Turel O,Korkmaz C,Karadogan MT,Yozgat CY,Iscan A,Sümbül B,Erenberk U

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:Neurotrophins and their cognate receptors TrkA, TrkB and TrkC regulate proliferation, differentiation and death of neuronal progenitor cells and may be implicated in the progression of medulloblastoma and other primitive neuroectodermal brain tumors (PNET). These common childhood brain tumors are composed of...

journal_title：Klinische Padiatrie

authors： Grotzer MA,Janss AJ,Phillips PC,Trojanowski JQ

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND:A fast and comprehensive diagnostic by means of whole-body CT has been shown to reduce mortality in the adult trauma population. Therefore whole-body CT seems to be the standard in adult trauma-patients. Due to the higher radiation exposure of whole-body CT the use of this diagnostic toll in pediatric trauma...

journal_title：Klinische Padiatrie

authors： Hilbert-Carius P,Hofmann GO,Lefering R,Stuttmann R,Bucher M,Goebel P,Gronwald GH

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:The aim of the present study was to evaluate paediatric reference values for platelet function using a point-of-care whole blood impedance aggregometry. METHODS, RESULTS & CONCLUSION: In 265 healthy infants and children aged

journal_title：Klinische Padiatrie

authors： Halimeh S,Angelis Gd,Sander A,Edelbusch C,Rott H,Thedieck S,Mesters R,Schlegel N,Nowak-Göttl U

更新日期：2010-05-01 00:00:00

abstract：:Report about cyclic agranulocytosis in a 10 1/2 years old girls, having stomatitis, sore throat and fever up to 39 degrees C in the interval of approximately 3 weeks since the age of 6 months. By the prophylactic treatment with pulverized tetracyclin, which is already given 2 days prior to the expected decrease of the...

journal_title：Klinische Padiatrie

authors： Schönberger W,Schönberger G,Stopfkuchen H

更新日期：1975-03-01 00:00:00

abstract：OBJECTIVE:To identify obstetric and neonatal risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) in high-risk preterm neonates. METHODS AND PATIENTS:Data from 279 preterm infants (246 mothers) with a gestational age≤28+0 weeks admitted to our NICU between January 2004 a...

journal_title：Klinische Padiatrie

authors： Waitz M,Nusser S,Schmid MB,Dreyhaupt J,Reister F,Hummler H

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Intrauterine growth restriction seems to be a risk factor for an aggravated course of secondary renal diseases in children. Catch-up growth after birth may play a critical role. We tested if there is an association between an aggravated course of nephritis in Henoch-Schönlein Purpura (PSHN) and low birth wei...

journal_title：Klinische Padiatrie

authors： Plank C,Vasilache I,Dittrich K,Dötsch J

更新日期：2010-12-01 00:00:00

abstract：:Oxygen saturation was determined non-invasively with the oxygenmet pulse wave oximeter 1471 and at the same time with the invasive reflectometric method. The determinations were carried out on 49 children (males = 24, females = 25) during 52 catherizations of the heart. Among these children aged between one week and 1...

journal_title：Klinische Padiatrie

authors： Krenkel R,Liappis N,Redel D,Hildenbrand G

更新日期：1981-07-01 00:00:00

abstract：:A two month old boy with Fournier's Gangrene of the scrotum as a result of unnecessary needle puncture of the hydrocele is being reported. The importance of appropriate diagnosis operation and drug-therapy is also described. ...

journal_title：Klinische Padiatrie

authors： Heemann KF,Homann W,Pistor K

更新日期：1984-11-01 00:00:00

abstract：:Prognostic factors to estimate the risk of relapse are crucial for risk-adapted therapy in acute lymphoblastic leukemia (ALL). In a cooperative multicenter treatment study for childhood ALL (COALL-03-85) the prognostic relevance of the bone marrow (BM) blast count at day 28 was evaluated. Treatment was adjusted to the...

journal_title：Klinische Padiatrie

authors： Janka-Schaub GE,Stührk H,Kortüm B,Graubner U,Jürgens H,Spaar HJ,Schöck V,Dohrn B,Bahr R,Winkler K

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND:Epidemiology and resistance patterns of bacterial pathogens in pediatric UTI show large interregional variability and rates of bacterial resistances are changing due to different antibiotic treatment. We intended to evaluate data from northern Germany. PATIENTS AND METHODS:In 100 children (53 female, 47 mal...

journal_title：Klinische Padiatrie

authors： Pape L,Gunzer F,Ziesing S,Pape A,Offner G,Ehrich JH

更新日期：2004-03-01 00:00:00

abstract：:This notebook which is of postcard size contains important information in case of emergency and details about the current illness and treatment. It contains follow-up information about the pattern of growth, endocrinological development and assessment of renal tubular function. The necessary follow-up investigations a...

journal_title：Klinische Padiatrie

authors： Maass E

更新日期：1994-07-01 00:00:00

abstract：:The rapid institution of empirical broad-spectrum antibiotics has become the gold standard of treatment for febrile neutropenic children undergoing therapy for cancer. With this approach, morbidity and mortality have dropped significantly but have not been eliminated altogether. In recent randomized studies evaluating...

journal_title：Klinische Padiatrie

authors： Laws HJ,Ammann RA,Lehrnbecher T

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:Congenital Central Hypoventilation Syndrome (CCHS, Ondine's curse) is a rare syndrome of dysfunction of the autonomic nervous system characterized by a decreased response to hypercarbia requiring mechanical ventilation in most cases. CCHS is an autosomal-dominant disease associated with tumors of neural cres...

journal_title：Klinische Padiatrie

authors： Hammel M,Klein M,Trips T,Priessmann H,Ankermann T,Holzinger A

更新日期：2009-09-01 00:00:00

abstract：:Important polymorphonuclear leukocyte (PMN) functions are dependent on an intact cytoskeleton, consistent of the microtubulus and microfilament system. This can be assayed from the mobility of fluorescence labelled Concanavalin A (Con A) receptor complexes on the cell surface. Con A shows an uniform surface distributi...

journal_title：Klinische Padiatrie

authors： Rister M,Statz A,Brucke G

更新日期：1983-09-01 00:00:00

abstract：:A severe hyperammonemia is the characteristic finding in patients with enzyme defects in urea cycle and one of the main causes of the acute metabolic crisis dsuring the newborn period and infancy. A case report is given about two male infants, who died in the age of one and of seven months respectively. In the second ...

journal_title：Klinische Padiatrie

authors： Schuchmann L,Colombo JP,Fischer H

更新日期：1980-05-01 00:00:00

abstract：:Wegener's granulomatosis is together with Churg-Strauss syndrome and microscopic polyangiitis a very rare cause of hemoptysis in childhood. We report on a 14 years old girl who developed arthralgia, purpura, glomerulonephritis and a diffuse alveolar haemorrhage with hemoptysis after a short time period of unspecific s...

journal_title：Klinische Padiatrie

authors： Heckmann M,Weber K,Reineck P,Schüler D,Geidel C,Steiss JO

更新日期：2006-01-01 00:00:00

abstract：:Hepatotoxicity of valproic acid (VPA) is reported in a psychomotor retarded boy. A four-month antiepileptic therapy was followed by a combined VPA/phenytoin treatment where-upon, two months later, the patient died in a hepatic coma. In the final state the metabolic pattern of VPA was still found within the normal rang...

journal_title：Klinische Padiatrie

authors： Keulen FP,Kochen W

更新日期：1985-09-01 00:00:00

abstract：:On our opinion one important indication for sonographic diagnosis in future are masses in the larynx area: in infancy or childhood mainly laryngeal papillomatosis. In one of our boy patients with massive laryngeal papillomatosis laser surgery was first performed at 15 months of age. After a second and third procedure ...

journal_title：Klinische Padiatrie

authors： Grunert D,Schöning M,Stier B,Klingebiel T

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Currently there are 3 pneumococcal vaccines available in Germany. The aim of this study is to evaluate the potential of the three currently available pneumococcal vaccines to reduce the burden of invasive pneumococcal disease in children. SUBJECTS:Children younger than 16 years who have been hospitalized be...

journal_title：Klinische Padiatrie

authors： Rückinger S,van der Linden M,Siedler A,von Kries R

更新日期：2011-03-01 00:00:00

abstract：:Infectious complications are a major cause of morbidity and mortality in pediatric and adult patients undergoing hematopoietic stem cell transplantation. The incidence and the severity code of infections depend on the function of the host's immune system. This function is strongly correlated to the application of immu...

journal_title：Klinische Padiatrie

authors： Schuster FR,Laws HJ

更新日期：2005-11-01 00:00:00

abstract：:Crohn's Disease and Ulcerative Colitis play a vital role in the differential diagnosis of inflammatory diseases of the colon during childhood. Pediatricians, radiologists, pediatric surgions and pediatric pathologists have been frequently confronted with the problem of distinguishing the two diseases. Morphologically,...

journal_title：Klinische Padiatrie

authors： Födisch HJ,Toledo R

更新日期：1978-03-01 00:00:00

abstract：:The German Society of Pediatric Oncology (GPO) designed a cooperative study to improve the outlook of patients with malignant (testicular) germ cell tumors. According to stage and histology of the tumor different surgical approaches to retroperitoneal lymphadenectomy are suggested. Local radiotherapy is not recommende...

journal_title：Klinische Padiatrie

authors： Haas RJ,Brämswig J,Göbel U,Harms D,Janka G,Weissbach L

更新日期：1983-05-01 00:00:00

abstract：:Since 1980, a growing number of pediatric patients with mutism following posterior fossa surgery have been recognized. This syndrome typically affects children and in rare cases young adults who become mute one or two days after tumor operation but do not show disturbances of consciousness or language comprehension. T...

journal_title：Klinische Padiatrie

authors： Janssen G,Messing-Jünger AM,Engelbrecht V,Göbel U,Bock WJ,Lenard HG

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:The role for testis-sparing surgery in the treatment of primary intratesticular lesions in childhood is growing. The reliability of scrotal ultrasonograpy (US) in the management of these lesions is still controversial. PATIENTS:Between 1991 and 2007, 383 children and adolescents presented with testicular ab...

journal_title：Klinische Padiatrie

authors： Tallen G,Hernáiz Driever P,Degenhardt P,Henze G,Riebel T

更新日期：2011-05-01 00:00:00

abstract：:Standards for supine length/height velocity from birth to 16 years (percentiles, mean and standard deviation) are presented, based on the longitudinal growth studies from Bonn and Dortmund. During the first two years of life growth velocity is twice to three times higher as in the following years. Many things point to...

journal_title：Klinische Padiatrie

authors： Brandt I,Reinken L

更新日期：1988-11-01 00:00:00

abstract：:Glutaracidemia/glutaraciduria type I is an acute or subacute neuropathic disorder of infancy or early childhood. The following symptoms characterize the clinical course: macrocephalus present at birth, cerebral atrophy revealed by CT or MRI scans, most striking in the frontal and temporal lobes, choreoathetosis and dy...

journal_title：Klinische Padiatrie

authors： Voll R,Hoffmann GF,Lipinski CG,Trefz FK,Weisser J

更新日期：1993-03-01 00:00:00

abstract：BACKGROUND:In study AML-BFM 87 the relapse rate was lower in patients receiving cranial irradiation (CRT). However, CRT has always been associated with adverse cognitive side effects. Therefore, the impact of CRT on neuropsychological function in children with AML was retrospectively evaluated. PATIENTS:We tested 53 c...

journal_title：Klinische Padiatrie

authors： Reinhardt D,Thiele C,Creutzig U,AML-BFM-Studiengruppe.

更新日期：2002-01-01 00:00:00