[Malignant testicular tumors in children and adolescents: concept of the MAHO 82 cooperative therapeutic study of the Society for Pediatric Oncology].

Abstract:

:The German Society of Pediatric Oncology (GPO) designed a cooperative study to improve the outlook of patients with malignant (testicular) germ cell tumors. According to stage and histology of the tumor different surgical approaches to retroperitoneal lymphadenectomy are suggested. Local radiotherapy is not recommended. Adjuvant chemotherapy with Vinblastine, Bleomycin and Cis-Platinum according to stage of disease, histologic classification and age of the patient is outlined. For non-responders or patients with only partial response an alternative aggressive chemotherapy with VP 16, Ifosfamide and Cis-Platinum is guidelined.

journal_name

Klin Padiatr

journal_title

Klinische Padiatrie

authors

Haas RJ,Brämswig J,Göbel U,Harms D,Janka G,Weissbach L

doi

10.1055/s-2008-1034068

subject

Has Abstract

pub_date

1983-05-01 00:00:00

pages

196-200

issue

3

eissn

0300-8630

issn

1439-3824

journal_volume

195

pub_type

杂志文章
  • CA 19-9, CA 50 and elastase 1 as additional markers of cystic fibrosis.

    abstract::Since reliable diagnosis of cystic fibrosis (CF) is still difficult, the occurrence of serum markers CA 19-9, CA 50 and elastase 1 was analysed. Serum levels of CA 19-9, CA 50, CA 125 and elastase 1 were estimated in 54 CF patients as well as in a control group of 66 children of similar age suffering from various othe...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033692

    authors: Uhlenbruck G,Scheuring U,Dienst C,Kaiser D,Roth B,Skopnik H

    更新日期:1988-03-01 00:00:00

  • [The diagnostic value of cytology of the CSF (author's transl)].

    abstract::Cytological examination of cerebrospinal fluid needs special techniques of cell collecting and staining. On condition of realizing the methodical requirements cytology of the cerebrospinal fluid brings more advancement in diagnostics than other laboratory examinations. The advantages of this procedure are: 1. Meningit...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Harms D

    更新日期:1975-03-01 00:00:00

  • Multiplate whole blood impedance point of care aggregometry: preliminary reference values in healthy infants, children and adolescents.

    abstract:BACKGROUND:The aim of the present study was to evaluate paediatric reference values for platelet function using a point-of-care whole blood impedance aggregometry. METHODS, RESULTS & CONCLUSION: In 265 healthy infants and children aged

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0030-1249081

    authors: Halimeh S,Angelis Gd,Sander A,Edelbusch C,Rott H,Thedieck S,Mesters R,Schlegel N,Nowak-Göttl U

    更新日期:2010-05-01 00:00:00

  • [Neonatal form of a nonketotic hyperglycinemia in consanguinous parents].

    abstract::This is a report of the neonatal form of nonketotic hyperglycinemia with rapid progressing neurological symptoms, respiratory distress and seizures. The EEG pattern is characteristic, the ratio of cerebrospinal fluid to plasma glycine abnormally high. The result of cranial computerized tomography demonstrates also in ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025473

    authors: Plöchl E,Rittinger O,Doringer E,Laubichler W

    更新日期:1991-11-01 00:00:00

  • [Increased incidence of developmental hip dysplasia in hypertrophic newborn infants].

    abstract::"Lack of space" in utero is considered to be a major factor in the aetiology of the congenital dislocation of the hip. This study tries to answer the question whether hypertrophy of a newborn has to be regarded as a risk factor on the basis of the principle mentioned above. The results of postnatal clinical and sonogr...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025256

    authors: Peschgens T,Skopnik H,Casser HR,Rauschning-Sikora K,Heimann G

    更新日期:1993-11-01 00:00:00

  • Neonatal Abstinence Syndrome: Twelve Years of Experience at a Regional Referral Center.

    abstract::Infants exposed to opiates antenatally display withdrawal symptoms after birth referred to as neonatal abstinence syndrome (NAS).A total of 366 newborns (166 females, 10 twins) from 361 mothers were diagnosed with NAS from 2000 to 2011 at a single large metropolitan referral center.Retrospective chart review of all ne...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0042-115300

    authors: Mücke S,Nagel M,Siedentopf J,Bührer C,Hüseman D

    更新日期:2017-01-01 00:00:00

  • Risk Factors Associated with Intraventricular Hemorrhage in Preterm Infants with ≤28 Weeks Gestational Age.

    abstract:OBJECTIVE:To identify obstetric and neonatal risk factors associated with the development of germinal matrix-intraventricular hemorrhage (GM-IVH) in high-risk preterm neonates. METHODS AND PATIENTS:Data from 279 preterm infants (246 mothers) with a gestational age≤28+0 weeks admitted to our NICU between January 2004 a...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0042-111689

    authors: Waitz M,Nusser S,Schmid MB,Dreyhaupt J,Reister F,Hummler H

    更新日期:2016-09-01 00:00:00

  • [Prevention of cytomegalic inclusion disease in leukemia patients with a cytomegalovirus hyperimmune globulin preparation].

    abstract::In a randomised study the efficacy of a cytomegalic hyperimmune globulin preparation (CMV-HIGP) which had been treated with beta-propiolactone was analysed. The study included 85 patients with acute lymphoblastic leukemia (ALL) and Non-B-Non-Hodgkin-lymphoma (NHL) who were treated initially or underwent a relapse ther...

    journal_title:Klinische Padiatrie

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1055/s-2008-1026722

    authors: Gerein V,Kropp H,Schwabe D,Gussetis E,Langer B,Kornhuber B

    更新日期:1989-07-01 00:00:00

  • A Snapshot of Pediatric Patients with COVID-19 in a Pandemic Hospital.

    abstract:AIM:Reports describing coronavirus disease 2019 (Covid-19) in children are fewer than adult studies due to milder clinical picture. We aimed to share our experience at a single center with an emphasis on collective decision making. MATERIALS AND METHODS:A suspected case was defined as the presence of symptoms suggesti...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/a-1263-1222

    authors: Duramaz BB,Turel O,Korkmaz C,Karadogan MT,Yozgat CY,Iscan A,Sümbül B,Erenberk U

    更新日期:2021-01-01 00:00:00

  • [Decrease in Group B Streptococcal Infections in Neonates: Analysis of Health Insurance Data 2005 to 2017].

    abstract:BACKGROUND:In the German guidelines for prophylaxis of group B streptococcal (GBS) early onset sepsis in neonates (EOS), GBS screening of all pregnant women has been recommended, but is not yet included in the Maternity Directives. Aim of the study was to identify temporal trends in incidence of EOS and their associati...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/a-1202-1758

    authors: Sorg AL,Obermeier V,Armann J,Klemme M,von Kries R

    更新日期:2021-01-01 00:00:00

  • [The clinical significance of pseudouridine determination of the urine in children and adolescents].

    abstract::A HPLC-method is described to determine the Pseudouridine/creatinine ratio in spontaneous urine samples in infancy and childhood. The urines of 74 healthy children between 1 and 18 years of age and of 231 children with different diseases were examined for this ratio, making 1097 measurements. 157 children suffered fro...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025295

    authors: Graf N,Bach K,Frisch B,Haas HJ,Sitzmann FC

    更新日期:1989-05-01 00:00:00

  • [Immunoglobulin and total protein concentrations in saliva of healthy children (author's transl)].

    abstract::The investigation of Immunoglobulins-and Total protein concentrations in saliva of healthy children shows an agreement with literature, a maturation in individual development of the saliva-producing organs in the mouth. ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035623

    authors: Tympner KD,Dörfler S

    更新日期:1980-09-01 00:00:00

  • Megestrol acetate to correct the nutritional status in an adolescent with growth hormone deficiency: Increase of appetite and body weight but only by increase of body water and fat mass followed by profound cortisol and testosterone depletion.

    abstract::Megestrol acetate (MA) is a synthetic, orally active derivative of the naturally occurring hormone progesterone. MA is increasingly used to correct loss of appetite and improve the nutritional status. We used MA in an adolescent with growth hormone (GH) deficiency due to former irradiation therapy in order to evaluate...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2002-25268

    authors: Schmid I,Stachel DK,Freudenberg S,Schmitt M,Schuster F,Haas RJ

    更新日期:2002-03-01 00:00:00

  • Treatment of multisystem Langerhans cell histiocytosis. Results of the DAL-HX 83 and DAL-HX 90 studies. DAL-HX Study Group.

    abstract:BACKGROUND:The prognosis of children with multisystem Langerhans cell histiocytosis (LCH) has improved with the application of chemotherapy. However, treatment strategies used varied from conservative approach with treatment only during disease exacerbation to intensive chemotherapy starting immediately after diagnosis...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2000-9667

    authors: Minkov M,Grois N,Heitger A,Pötschger U,Westermeier T,Gadner H

    更新日期:2000-07-01 00:00:00

  • [The Value of Conventional Radiographs of the Pelvis in Detection of Perthes Disease 3 Months After an Episode of Acute Transient Synovitis].

    abstract::Background: Transient synovitis is the most common hip joint disorder in children. Perthes disease occurs around the same age and may not be distinguishable to an episode of transient synovitis in the early stage. Therefore all children in our clinic with transient synovitis underwent a follow-up X-ray 3 months later ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0042-116150

    authors: Lenoir U,Slongo T,Aghayev E,Joeris A

    更新日期:2017-03-01 00:00:00

  • [Doppler echocardiographic investigation of left ventricular diastolic function in preterm infants with and without a patent ductus arteriosus].

    abstract::We studied the influence of preload augmentation on Doppler-derived left ventricular diastolic function parameters in infants with a birth weight <1500 g. In 44 neonates with a closed duct and 29 neonates with an open ductus arteriosus a complete echocardiographic study including Doppler investigations of the mitral i...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2004-817684

    authors: Schmitz L,Stiller B,Koehne P,Koch H,Lange PE

    更新日期:2004-01-01 00:00:00

  • [Neurofibromatosis type 1 and associated clinical abnormalities in 27 children].

    abstract::Neurofibromatosis type 1 is the most common of the phakomatoses and the clinical follow-up is an interdisciplinary challenge. The data of 27 patients with NF1 were systematically reviewed and compared to data from the literature. All of our patients had clinical signs of NF1. Besides the classic criteria café-au-lait ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-973086

    authors: Syrbe S,Eberle K,Strenge S,Bernhard MK,Herbertz S,Bierbach U,Hirsch W,Froster UG,Kiess W,Merkenschlager A

    更新日期:2007-11-01 00:00:00

  • [Wiedemann-Beckwith syndrome: clinical characteristics, constitutional chromosome abnormalities and tumor incidence].

    abstract::The observation of constitutional chromosome abnormalities in a one and half year old boy with Wiedemann-Beckwith syndrome (WBS) and hepatoblastoma prompted us to review the currently available literature dealing with this subject. In approximately 500 published cases with complete and incomplete forms of WBS, 42 mali...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1026804

    authors: Haas OA,Zoubek A,Grümayer ER,Ferstl G,Gadner H

    更新日期:1987-07-01 00:00:00

  • [Cognitive and motor abilities and behavioural outcome in children after neonatal operation with cardiopulmonary bypass].

    abstract:BACKGROUND:Empirical results about the cognitive, motor and psychic development in patients with d-transposition of the great arteries after arterial switch operation remain unclear. Potential reasons are the patients' initial status, improved perinatal care or the quality of surgery. To exclude quality of surgery as t...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-985863

    authors: Vahsen N,Kavsek M,Toussaint-Götz N,Schneider K,Urban AE,Schneider M

    更新日期:2009-01-01 00:00:00

  • [Rheumatic iridocyclitis in childhood--differentiation on the basis of clinical and immunological parameters (author's transl)].

    abstract::In approximately 10% of the children suffering from juvenile chronic arthritis (JCA), rheumatic iridocyclitis was also diagnosed. In 90 JCA and iridocyclitis patients we studied relative risk, clinical course and prognosis by means of several clinical and immunological parameters. Antinuclear antibodies (ANA), selecti...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033783

    authors: Michels H,Schuchmann L,Truckenbrodt H,Renz K

    更新日期:1982-03-01 00:00:00

  • Long-term outcome after neonatal parenchymatous brain lesions.

    abstract:BACKGROUND:Although considered of high prognostic impact, knowledge on the long-term outcome after neonatal parenchymatous brain lesions (PBL) is limited. PATIENTS:29 children with either unilateral (n = 19) or bilateral (n = 10) hemorrhagic/ischemic PBL. METHODS:The patients were reinvestigated at 9 9/12 +/- 3 4/12 ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2004-44900

    authors: Häusler M,Merz U,Van Tuil C,Ramaekers VT

    更新日期:2004-07-01 00:00:00

  • [Tumor necrosis factor in the serum--a useful supplemental parameter in the diagnosis of infection in cystic fibrosis?].

    abstract::In 15 patients with cystic fibrosis 18 blood samples were investigated for signs of infection including full white blood count, c-reactive protein (CRP) and tumour-necrosis-factor alpha (TNF). Ten patients were hospitalized for pulmonary exacerbation, one for orthostatic collapse and one for equivalent of meconium ile...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025422

    authors: Heininger U,Böwing B,Forster D,Berthold M

    更新日期:1991-05-01 00:00:00

  • [Septicaemia in the neonatal and infant period (author's transl)].

    abstract::The paper reported about septicaemia in the neonatal and infant period. Continuing former investigations by Kienitz in the same pediatric clinic we have got a survey from 1933 to 1974. In the last years we saw increasingly more infections with gram-negative organisms, especially by Pyocyaneus with a severe prognosis. ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Diekmann L,Kotzur J

    更新日期:1976-03-01 00:00:00

  • [Bacterial cervical lymphadenitis--surgical aspects].

    abstract::In a retrospective study we evaluated clinical features and diagnostic impact of sonography, white blood cell count, C-reactive protein as well as bacterial etiology of children treated surgically for bacterial cervical lymphadenitis. We report on 38 children at the age between 2.5 months and 14 years who were admitte...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2003-41403

    authors: Tröbs RB,Gräfe G,Müller P,Handrick W

    更新日期:2003-07-01 00:00:00

  • Leukapheresis and exchange transfusion in children with acute leukemia and hyperleukocytosis. A single center experience.

    abstract:BACKGROUND:The risk of severe complications or death during the initial period of acute leukemia was markedly decreased due to the progress in pediatric oncology and use of simple measures like hyperhydration, forced diuresis, treatment of hyperuricemia, correction of electrolyte and coagulation disturbances and the ca...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-0029-1239533

    authors: Haase R,Merkel N,Diwan O,Elsner K,Kramm CM

    更新日期:2009-11-01 00:00:00

  • [A case of X/X translocation: t(X;X) (q26;p11)].

    abstract::An eight-year old girl showing a X/X-translocation (45,X/46,Xt(X;X)(q26;p11)) is presented. Besides short stature and congenital heart-anomaly no other phenotypical abnormalities were present. In all cells containing the abnormal X-chromosome, the latter was late labeling as shown by autoradiography and BrdU-labeling....

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:

    authors: Wagenbichler P,Frisch H,Schnedl W

    更新日期:1975-11-01 00:00:00

  • Probiotics for prevention of necrotising enterocolitis: an updated meta-analysis.

    abstract::Several randomized controlled trials (RCTs) have investigated the prophylactic use of probiotics in preterm infants aimed at reducing the rate of necrotising enterocolitis (NEC). There are 4 meta-analyses on this subject. 2 more RCTs have been published since these meta-analyses were completed. Each meta-analysis, as ...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章,meta分析

    doi:10.1055/s-0030-1254113

    authors: Guthmann F,Kluthe C,Bührer C

    更新日期:2010-09-01 00:00:00

  • [Interferons--biologic principles and clinical uses].

    abstract::Interferons are components of the nonspecific defense system. Their most prominent biological roles are the antiviral, the antiproliferative, and the immunoregulatory activities. However, their primary functions within the organism remains to be determined. Three types of IFNs have been described so far (IFN alpha, IF...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1033980

    authors: Jacobsen H,Kirchner H

    更新日期:1985-07-01 00:00:00

  • [Click-evoked otoacoustic emissions and acoustic brain stem potentials in early detection of hearing disorders in premature and newborn infants after neonatal critical care].

    abstract::Evoked otoacoustic emissions (EOAE) and brainstem acoustic evoked potentials (BAEP) were recorded from 78 children following neonatal intensive care. In 23% no EOAE could be obtained. Hearing impairment in the BAEP was found in 9%. In 22% negative EOAE were found in spite of normal BAEP. According to the latency-inten...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046586

    authors: Lauffer H,Pröschel U,Gerling S,Wenzel D

    更新日期:1994-03-01 00:00:00

  • [The portal system and hepatic artery in children with biliary atresia. 1: Ultrasound and simple duplex ultrasound parameters].

    abstract::In 37 children with extrahepatic biliary atresia between 12 days in 9 years of age we performed 72 duplexsonographic examinations of the portal system and the hepatic artery. In the control group we investigated 61 healthy children. All investigations were performed with computer sonography (Acuson 128) with a 3.5 MHz...

    journal_title:Klinische Padiatrie

    pub_type: 杂志文章

    doi:10.1055/s-2007-1025481

    authors: Grunert D,Stier B,Schöning M

    更新日期:1990-01-01 00:00:00