Abstract:
:Adult male rats were injected with 6-hydroxydopamine, either into the lateral brain ventricle or directly into the dorsal hippocampus. They were adrenalectomized 5-7 days later, and following an additional 24 hours, the specific in vitro 3H-corticosterone binding capacity of dorsal hippocampal slices was determined by estimation of uptake of radioactivity by the nuclear fraction. Specific corticosterone binding was reduced by 40-50% in both experimental groups, as compared to vehicle-treated controls. These results suggest that the maintenance of normal dorsal hippocampal corticosterone binding capacity is dependent upon the integrity of endogenous brain catecholaminergic neural systems.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Weidenfeld J,Siegel RA,Corcos AP,Chen M,Feldman S,Chowers Idoi
10.1007/BF00237156subject
Has Abstractpub_date
1983-01-01 00:00:00pages
121-4issue
1eissn
0014-4819issn
1432-1106journal_volume
52pub_type
杂志文章abstract::Load perturbations were applied to the arm of human subjects under conditions where both limb segments (upper arm and forearm) were free to move. The perturbations consisted of pulses of torque 50 ms in duration and of pseudo-random sequences of such pulses. They were applied to either the forearm or the upper arm. Un...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237573
更新日期:1986-01-01 00:00:00
abstract::How the CNS deals with the issue of motor redundancy remains a central question for motor control research. Here we investigate the means by which neuromuscular and biomechanical factors interact to resolve motor redundancy in rhythmic multijoint arm movements. We used a two-df motorized robot arm to manipulate the dy...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1437-2
更新日期:2008-08-01 00:00:00
abstract::In order to assess the autoinhibitory control of endogenous acetylcholine (ACh) in rat and human neocortex, slices of these tissues were prelabelled with [(3)H]choline, superfused continuously and stimulated electrically using various frequencies in the presence or absence of drugs. The autoinhibitory feedback control...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050858
更新日期:1999-10-01 00:00:00
abstract::The cortical projections to neck muscle motoneurons were studied in normal subjects by electrical and magnetic transcranial brain stimulation. After magnetic stimulation with a large coil, motor evoked potentials were present in about 20% of relaxed and 100% of contracting neck muscles. The latency of these responses ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231857
更新日期:1991-01-01 00:00:00
abstract::Geniculate cell responses to moving bars and moving texture were compared in normal cats and in cats in which the corticofugal feedback was removed by cortical ablation. In experimental animals the response strength and the velocity upper cutoff assessed with a moving bar was reduced compared to control animals. The s...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00608257
更新日期:1990-01-01 00:00:00
abstract::Abundant evidence has revealed that social observation could enhance people's norm-enforcement behaviors to norm violators. However, whether such enhancement is strategically reputation-based without changes on awareness of social norms or it is accompanied with strengthened perception of norm violations remains uncle...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05762-6
更新日期:2020-05-01 00:00:00
abstract::The actions of alpha-kainic acid (KA) were reexamined in thin sections of the hippocampus and the cerebellum of the guinea pig in view of various discrepancies between our previous findings and reports from other laboratories. Brief pulses of KA ejected in st. lucidum in the CA3 region induced short- and long-lasting ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248508
更新日期:1988-01-01 00:00:00
abstract::X-ray photography was employed to analyse the postural syndromes following unilateral global and selective lesions of the vestibular apparatus in guinea pigs. Following hemilabyrinthectomy, head rotation in the horizontal plane resulted mainly from rotation of the cervical vertebrae whereas lateral head tilt was due t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00250579
更新日期:1989-01-01 00:00:00
abstract::The total number of granule cells in the dentate gyrus was estimated in 17 male rats, four each aged 30, 120, and 200 days, and five aged 365 days. There is a substantial 35-43% linear increase between 1 month and 1 year. Two parameters of the granular layer are involved in the numerical change. First, total granular ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238626
更新日期:1982-01-01 00:00:00
abstract::Head-fixed gaze shifts were evoked by electrical stimulation of the deeper layers of the cat superior colliculus (SC). After a short latency, saccades were triggered with kinematics similar to those of visually guided saccades. When electrical stimulation was maintained for more than 150-200 ms, postsaccadic smooth ey...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230420
更新日期:1996-01-01 00:00:00
abstract::Chemoreceptor pathways from the vomeronasal organ (VNO), and main olfactory system are known to be separate as they pass into the brain, at least until the level of the amygdala. In the amygdala, vomeronasal pathways project to the posteromedial cortical nucleus (PMCN), and medial nucleus (MN). The main olfactory path...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247024
更新日期:1987-01-01 00:00:00
abstract::Recent studies suggest that recreational use of cocaine is associated with significant impairments in the same cognitive control functions that are affected by chronic use. Here we tested whether recreational cocaine use can impact the emergence and resolution of response conflict in conflict-inducing tasks. Recreatio...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3724-9
更新日期:2014-01-01 00:00:00
abstract::Many previous studies have demonstrated the existence of neurons with tremor-frequency activity ("tremor cells") in the thalamus of Parkinson's disease (PD) patients and these neurons are presumed to play a role in the pathogenesis of tremor. Since a major input to motor thalamus (Voa and Vop) is from the internal seg...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005606
更新日期:1997-03-01 00:00:00
abstract::Little is known about mechanisms used by the nervous system to encode time. In light of recent evidence, cerebellar cortex involvement in the learned timing of conditioned eyelid responses shows promise as an area of investigation into neural timing mechanisms. Lesion studies indicate that the cerebellar cortex is nec...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s002210050443
更新日期:1998-07-01 00:00:00
abstract::The neuronal responsiveness to three-dimensional (3D) motion in cat posteromedial lateral suprasylvian (PMLS) cortex was studied using a computer-controlled, stereoscopic 3D graphic display capable of reproducing the major visual cues for natural 3D motion, including motion disparity, size, texture, and shading change...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050509
更新日期:1998-09-01 00:00:00
abstract::Saccade characteristics in response to moving and stationary targets were studied in three monkeys (Macaca mulatta) that had been trained to look at a target, which after an initial jump either remained in place or moved forward or backward with constant velocity (10 degrees /s). Eye movements were recorded using a se...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2070-3
更新日期:2005-02-01 00:00:00
abstract::When reaches are performed toward target objects, the presence of other non-target objects influences kinematic parameters of the reach. A typical observation has been that non-targets positioned ipsilaterally to the acting limb interfere more with the trajectory of the hand than contralateral non-targets. Here, we in...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3615-0
更新日期:2013-09-01 00:00:00
abstract::Hyper-gravity provides a unique environment to study how misperceptions impact control of orientation relative to gravity. Previous studies have found that static and dynamic roll tilts are perceptually overestimated in hyper-gravity. The current investigation quantifies how this influences control of orientation. We ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4215-y
更新日期:2015-05-01 00:00:00
abstract::We studied Fos expression in the central nociceptive pathways at different sedative levels in order to clarify the central mechanism of propofol's nociceptive action. Sprague-Dawley rats received propofol (PRO) or pentobarbital (PEN) and were divided into two groups with different doses of drug administration (light a...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0779-x
更新日期:2007-05-01 00:00:00
abstract::We examined modulation of transmission of short-latency excitation produced by distal hindlimb cutaneous input, as well as fluctuations in motoneuron membrane potential and input resistance, in flexor digitorum longus (FDL) motoneurons during fictive locomotion. Fictive stepping was induced in unaesthetized, decerebra...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248749
更新日期:1988-01-01 00:00:00
abstract::The objective of this study was to investigate interhemispheric transcallosal connections between primary motor cortices noninvasively in awake human subjects. For this purpose, focal transcranial magnetic stimulation was performed on eight healthy, right-handed subjects and one patient with congenital collosal agenes...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227944
更新日期:1996-12-01 00:00:00
abstract::Previous research has shown that the timing of a sensor-motor event is recalibrated after a brief exposure to a delayed feedback of a voluntary action (Stetson et al. 2006). Here, we examined whether it is the sensory or motor event that is shifted in time. We compared lag adaption for action-feedback in visuo-motor p...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-2047-3
更新日期:2010-03-01 00:00:00
abstract::Limb proprioception is an awareness by the central nervous system (CNS) of the location of a limb in three-dimensional space and is essential for movement and postural control. The CNS uses the position of the head and neck when interpreting the position of the upper limb, and altered input from neck muscles may affec...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4240-x
更新日期:2015-05-01 00:00:00
abstract::Two-shock inhibition, a feature of 98 of 100 P cells recorded in the dorsal lateral geniculate nucleus of the normal rat, was not observed in 91 of 140 geniculate cells after an electrolytic lesion had been made in the adjacent visually responsive thalamic reticular nucleus. Nine geniculate cells recorded both before ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237834
更新日期:1985-01-01 00:00:00
abstract::The afferent volley generated during neuromuscular electrical stimulation (NMES) can increase the excitability of the human corticospinal (CS) pathway. This study was designed to determine the effect of different frequencies of NMES applied over the common peroneal nerve on changes in CS excitability for the tibialis ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2202-x
更新日期:2010-05-01 00:00:00
abstract::We had recumbent subjects (n = 7) indicate the amplitude of imposed, passive yaw-axis body rotations in the 0, 1, and 1.8 g background force levels generated during parabolic flight maneuvers. The blindfolded subject, restrained in a cradle, aligned a gravity-neutral pointer with the subjective vertical while in an in...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1785-6
更新日期:2009-05-01 00:00:00
abstract::The purpose of this study was to compare the asymmetric gait induced by unilateral spinal cord injury in chicks with asymmetric gaits of other bipeds and quadrupeds. After lateral hemisection of the left thoracic spinal cord, kinetic (ground reaction forces) and kinematic (distance and timing) data were recorded as ch...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050515
更新日期:1998-10-01 00:00:00
abstract::This study investigated whether the execution of an accurate pointing response depends on a prior saccade orientation towards the target, independent of the vision of the limb. A comparison was made between the accuracy of sequential responses (in which the starting position of the hand is known and the eye centred on...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/BF00228987
更新日期:1994-01-01 00:00:00
abstract::This study examined precision-grip force applied to an instrumented test object held aloft while the weight of the object was predictably varied by transporting and placing loads (50, 100, or 200 g) atop the test object. Transport of the loads was performed either by the subject or the experimenter. Grip force was exa...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000337
更新日期:2000-06-01 00:00:00
abstract::In the present article a number of comparative lesion studies in two inbred strains of mice (C57BL/6 and DBA/2) with different levels of radial maze performance are reviewed. The effects of lesions in several brain areas on maze learning were investigated, thus revealing strain differences in the neural circuitry subs...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s002210050542
更新日期:1998-11-01 00:00:00