Abstract：
:The actions of alpha-kainic acid (KA) were reexamined in thin sections of the hippocampus and the cerebellum of the guinea pig in view of various discrepancies between our previous findings and reports from other laboratories. Brief pulses of KA ejected in st. lucidum in the CA3 region induced short- and long-lasting depolarizations in neurons nearby, whereas those ejected in st. radiatum or st. oriens induced only short-lasting responses. Neurons in CA1 region and Purkinje cells in the cerebellum generated only short-lasting depolarizations in response to KA pulses ejected in their dendritic fields. The short-lasting KA responses in CA1 region were sensitive to gamma-D-glutamylglycine and pentobarbital. The slow KA responses were suppressed by kynurenic acid. They were not accompanied by increases in extracellular potassium concentration. These results suggest that the mossy fiber-innervated portions of the surface membrane of CA3 neurons have a type of KA receptor different from those ubiquitously distributed in central neurons.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Sawada S,Higashima M,Yamamoto Cdoi
10.1007/BF00248508subject
Has Abstractpub_date
1988-01-01 00:00:00pages
135-40issue
1eissn
0014-4819issn
1432-1106journal_volume
72pub_type
杂志文章abstract：:Local anesthetic may cause neurotoxicity in developing neurons. In this study, we examined the molecular mechanisms of microRNA-210 (miR-210) in regulating bupivacaine-induced dorsal root ganglia (DRG) neurotoxicity in vitro. Young mouse (P30) DRG explants were cultured in vitro and treated with 5 mM bupivacaine to in...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4513-4
更新日期：2016-04-01 00:00:00
abstract：:Quick detection of changes in the sensory environment is very important for survival, resulting in automatic shifts of attention to the event and the facilitation of subsequent processes to execute appropriate behaviors. The abrupt onset or offset of a sensory stimulus should also activate the neural network detecting...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1468-8
更新日期：2008-09-01 00:00:00
abstract：:The human visual system is strikingly insensitive to speed changes attributed to the need to infer visual acceleration, observed during stationary fixation, indirectly by comparing velocities integrated over time. The objective of this study was to test if smooth pursuit eye movements improve the detection of speed ch...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0216-6
更新日期：2006-04-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228153
更新日期：1990-01-01 00:00:00
abstract：:The cerebral representation of space depends on the integration of many different sensory inputs. The vestibular system provides one such input and its dysfunction can cause profound spatial disorientation. Using positron emission tomography (PET), we measured regional cerebral perfusion with various vestibular stimul...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/BF00241421
更新日期：1994-01-01 00:00:00
abstract：:Linear and angular control of trunk and leg motion during curvilinear navigation was investigated in subjects with cerebellar ataxia and age-matched control subjects. Subjects walked with eyes open around a 1.2-m circle. The relationship of linear to angular motion was quantified by determining the ratios of trunk lin...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3074-z
更新日期：2012-05-01 00:00:00
abstract：:Effects of electrical stimulation of the ipsilateral tooth pulp (TP) on C1 spinal neurons were determined in 33 anesthetized rats. One hundred and seven neurons responded to TP stimulation. In 10 rats, the activity of 18 C1 spinal neurons and the amplitude of a digastric electromyogram (dEMG, n = 10) increased proport...
journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：1999-06-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0981-9
更新日期：2002-03-01 00:00:00
abstract：:Response time, or latency, is increasingly being used to provide information about neural decision processes. LATER (Linear Approach to Threshold with Ergodic Rate) is a quasi-Bayesian model of decision-making, with the additional feature that it introduces a degree of gratuitous randomisation into the decision proces...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2587-1
更新日期：2011-04-01 00:00:00
abstract：:It is generally accepted that transferrin receptor is located in the endothelial cells of the brain, but its existence in other brain cell types is less established. In this study, a [(125)I]transferrin binding assay was used to determine whether there is transferrin receptor on the membrane of cultured rat cortical a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050916
更新日期：1999-12-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229030
更新日期：1993-01-01 00:00:00
abstract：:Associations between cognitive and motor timing performance are documented in hundreds of studies. A core finding is a correlation of about - 0.3 to - 0.5 between psychometric intelligence and time interval production variability and reaction time, but the nature of the relationship remains unclear. Here, we investiga...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05780-4
更新日期：2020-04-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-2240-y
更新日期：2005-07-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231054
更新日期：1991-01-01 00:00:00
abstract：:Motor control tasks like stance or object handling require sensory feedback from proprioception, vision and touch. The distinction between tactile and proprioceptive sensors is not frequently made in dynamic motor control tasks, and if so, mostly based on signal latency. We previously found that force control tasks en...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3341-z
更新日期：2013-02-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-4122-7
更新日期：2015-02-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2018-7
更新日期：2005-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-2047-3
更新日期：2010-03-01 00:00:00
abstract：:The photothrombotic ring stroke model with sustained underperfusion followed by late spontaneous reperfusion (Gu et al. 1999) was employed to study its morphological consequences. The exposed crania of adult male Wistar rats were subjected to a ring-shaped laser irradiation beam simultaneously with intravenous erythro...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050672
更新日期：1999-03-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1547-x
更新日期：2009-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：2011-01-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：2007-04-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：2014-11-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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更新日期：2008-03-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231171
更新日期：1991-01-01 00:00:00
abstract：:During fast, saccadic eye movements visual perception is suppressed. This saccadic suppression prevents erroneous and distracting motion percepts resulting from saccade induced retinal slip. Although saccadic suppression occurs over a substantial time interval around the saccade, there is no "perceptual gap" during sa...
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pub_type： 杂志文章
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更新日期：2007-07-01 00:00:00
abstract：:Human observers are experts at visual face recognition due to specialized visual mechanisms for face processing that evolve with perceptual expertize. Such expertize has long been attributed to the use of configural processing, enabled by fast, parallel information encoding of the visual information in the face. Here ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3463-y
更新日期：2013-05-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005653
更新日期：1997-05-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
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