Abstract:
:The cerebral representation of space depends on the integration of many different sensory inputs. The vestibular system provides one such input and its dysfunction can cause profound spatial disorientation. Using positron emission tomography (PET), we measured regional cerebral perfusion with various vestibular stimulations to map central vestibular projections and to investigate the cerebral basis of spatial disorientation. We showed that the temporoparietal cortex, the insula, the putamen, and the anterior cingulate cortex are the cerebral projections of the vestibular system in man and that the spatial disorientation caused by unilateral vestibular stimulation is associated with their asymmetric activation.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Bottini G,Sterzi R,Paulesu E,Vallar G,Cappa SF,Erminio F,Passingham RE,Frith CD,Frackowiak RSdoi
10.1007/BF00241421subject
Has Abstractpub_date
1994-01-01 00:00:00pages
164-9issue
1eissn
0014-4819issn
1432-1106journal_volume
99pub_type
临床试验,杂志文章abstract::The reduction in saccade latency when the fixation point is removed (fixation offset effect-FOE) reflects the degree to which fixation neurons are under influence by a stimulus at fixation. Strategic manipulations of oculomotor readiness that bring these neurons under endogenous control reduce the magnitude of the FOE...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1655-7
更新日期:2009-02-01 00:00:00
abstract::Recordings were made in the peroneal nerve of healthy volunteer subjects from C-mechano-heat (CMH) nociceptors (n=25) with their receptive fields in the skin on the dorsum of the foot. The investigation focused on afferent single C-fiber activity induced by short (200 ms) high-intensity argon-laser light pulses projec...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s002210050489
更新日期:1998-09-01 00:00:00
abstract::The position of the center of gravity (CG) is a reference value that is controlled by the nervous system during the performance of movements. In order to maintain equilibrium, leg movement is preceded by a shift of the CG towards the supporting side. This CG shift is initiated by an early displacement of the center of...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050453
更新日期:1998-07-01 00:00:00
abstract::Although postural control requires the integration of different sensory cues, little is known about the role of attentional artifacts on the individual's ability to properly respond to postural challenges. This study investigated the effects of concomitant tasks (cognitive and postural) on the relationship between vis...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4762-x
更新日期:2016-12-01 00:00:00
abstract::The role of kinaesthetic afferences in controlling coupling of voluntary oscillation of the hand and foot, both in-phase and anti-phase, was investigated by modifying the mechanical properties of one of the two segments (the hand) with applied inertial or elastic loads. Loads consisted of a lead disk, rotating coaxial...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210100762
更新日期:2001-07-01 00:00:00
abstract::The representation of the two eyes in striate cortex (V1) of Cebus monkeys was studied by electrophysiological single-unit recordings in normal animals and by morphometric analysis of the pattern of ocular dominance (OD) stripes, as revealed by cytochrome oxidase histochemistry in V1 flat-mounts of enucleated animals....
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF02259100
更新日期:1992-01-01 00:00:00
abstract::The present experiment investigated the effects of aging on emotional behavior, without concomitant influences from any previous behavioral manipulation apart from weighing the rats. Anxiety-related behaviors were measured in the elevated plus-maze (EPM). Performance in the open field (OF) was also assessed to control...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2240-y
更新日期:2005-07-01 00:00:00
abstract::In an earlier posturographic investigation (Collins and De Luca 1993) it was proposed that open-loop and closed-loop control mechanisms are involved in the regulation of undisturbed, upright stance. In this study, stabilogram-diffusion analysis was used to examine how visual input affects the operational characteristi...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/BF00241972
更新日期:1995-01-01 00:00:00
abstract::The actions of alpha-kainic acid (KA) were reexamined in thin sections of the hippocampus and the cerebellum of the guinea pig in view of various discrepancies between our previous findings and reports from other laboratories. Brief pulses of KA ejected in st. lucidum in the CA3 region induced short- and long-lasting ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248508
更新日期:1988-01-01 00:00:00
abstract::We investigated the association between the degree of lesion overlap with the corticospinal tract and walking performance before and after 4-weeks of partial body weight support (PBWS) treadmill training in 18 individuals (ten male, eight female) with a mean age 59 +/- 13 years (mean +/- SD), range 32-74 years, who we...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-1237-0
更新日期:2008-03-01 00:00:00
abstract::The cerebrovascular consequences of the gentle restraint commonly used for the measurement of local cerebral blood flow (LCBF) in conscious rats has been tested by using two drugs, propranolol and diazepam. Propranolol induced small LCBF decreases in 7 structures suggesting that the cerebral circulation was partially ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235660
更新日期:1986-01-01 00:00:00
abstract::Dorsomedial frontal cortex (DMFC) was studied in monkeys trained to make visually guided eye or arm movements. Portions of DMFC are involved in the execution of learned, goal-directed behaviors. Many neurons discharge with both eye and hand movements as well as when motor responses are withheld, provided these behavio...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247300
更新日期:1988-01-01 00:00:00
abstract::Observing an action activates action representations in the motor system. Moreover, the representations of manipulable objects are closely linked to the motor systems at a functional and neuroanatomical level. Here, we investigated whether action observation can facilitate object recognition using an action priming pa...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1953-8
更新日期:2010-01-01 00:00:00
abstract::The development of visual cell properties was studied in cortical Area 18 (A18) of normal (NRs) and dark-reared kittens (DRs), from 2 weeks of age to adulthood. In addition to the orientation selective (S) and non-selective (NS) cells, we describe a new type of non-selective cell with a peripheral zone (NSp), which co...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247518
更新日期:1988-01-01 00:00:00
abstract::Injections of tritiated tracer precursors into one eye revealed a highly variable lamination pattern of the LGN in the marmoset Callithrix. In one specimen, only four cell layers were apparent with some indication of further differentiation. In a second specimen, six almost complete relay layers were found in the occi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235574
更新日期:1978-11-15 00:00:00
abstract::Fourteen healthy adults were tested to assess the potential influence on stance maintenance of two parts of the visual feedback technique (display scale and time delay). The task consisted in their keeping a spot on the screen representing their center of pressure, CoP (i.e. successive points of application of the gro...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2288-8
更新日期:2005-08-01 00:00:00
abstract::During normal postnatal development, there is an overproduction and subsequent partial elimination of the callosal projections of cortical areas 17 and 18 in the cat. In the present study, we investigated how neonatal splitting of the optic chiasm affects this process. Our results indicate that neonatal splitting of t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00242013
更新日期:1995-01-01 00:00:00
abstract::Motor-unit activity in m. biceps brachii during isometric flexion contractions has been compared with motor-unit activity during a) slow voluntary movements against constant or increasing preloads and b) flexion contractions while movements were imposed by a torque motor. Recruitment levels and firing frequency behavi...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228882
更新日期:1990-01-01 00:00:00
abstract::The motor cortex contains a distributed map of muscles, with a single muscle represented over a wide cortical area. We have searched for inter-connections between distant sites projecting to common muscles by delivering pairs of 20-microA single-pulse intracortical microstimuli (ICMS) to sites separated by 1.5-2 mm in...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050585
更新日期:1998-12-01 00:00:00
abstract::The purposes of this pilot study were to create a model of focal cortical ischemia in Macaca fascicularis and to explore contributions of the reticulospinal system in recovery of reaching. Endothelin-1 was used to create a focal lesion in the shoulder/elbow representation of left primary motor cortex (M1) of two adult...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4390-x
更新日期:2015-11-01 00:00:00
abstract::Evidence is presented that simple cells in the cat striate cortex (area 17) fail to respond to two dimensional random patterns but respond vigorously to one dimensional patterns with identical power at the preferred orientation of the cell. Further observations suggest that complex cells inhibit simple cells so as to ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238391
更新日期:1981-01-01 00:00:00
abstract::In a choice reaction time (RT) paradigm, providing partial advance information (a precue) about the upcoming response has been shown to decrease RT, presumably due to preprogramming of the precued parameters. When advance information about a particular aspect of a movement is provided (precued), several different stra...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2893-7
更新日期:2011-12-01 00:00:00
abstract::Four experiments were performed with macaque monkeys (rhesus, Macaca mulatta, and cynomolgus, M. fascicularis). In experiment 1 six rhesus monkeys learned pre-operatively to perform delayed matching-to-sample, with complex naturalistic scenes as the stimulus material. Three of these monkeys then received bilateral abl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228977
更新日期:1994-01-01 00:00:00
abstract::We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered bilaterally at 0.2-2.0 Hz, evokes a potent entrainment of sympathetic outflow to muscle and skin. Most recently, we showed that stimulation at 0.08-0.18 Hz generates two bursts of modulation of muscle sympathetic nerve activity ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3090-z
更新日期:2012-06-01 00:00:00
abstract::The properties of sensory reweighting for control of human upright stance have primarily been investigated through experimental techniques such as sinusoidal driving of postural sway. However, other forms of visual inputs that are commonly encountered, such as translation, may produce different adaptive responses. We ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0502-y
更新日期:2006-10-01 00:00:00
abstract::The present study was undertaken to investigate the effects of the alpha2 adrenergic agonist, clonidine, on the near complete cerebral ischemia (NCFI) evoked release of glutamate and aspartate from normo- and hyperglycemic rodent brain tissue using microdialysis tissue techniques. Hemodynamic variables, blood lactate,...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-0064-4
更新日期:2005-12-01 00:00:00
abstract::Extracellular single-neuron recordings were obtained from electrophysiologically identified nigrostriatal neurons in chloral hydrate anesthetized rats, in order to test the hypothesis that excitatory amino acid receptors are involved in responses of these neurons to electrical stimulation of the pontine region where t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229003
更新日期:1992-01-01 00:00:00
abstract::The contribution of ventral stream information to the variability of movement has been the focus of much attention, and has provided numerous researchers with conflicting results. These results have been obtained through the use of discrete pointing movements, and as such, do not offer any explanation regarding how ve...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0453-3
更新日期:2006-09-01 00:00:00
abstract::During the flight of Spacelab-1 a series of vestibular experiments was performed on the crew by a group of European investigators. Control experiments were carried out on the same subjects pre- and postflight. The tests included caloric stimulation of the ears, threshold measurements of response to linear acceleration...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237739
更新日期:1986-01-01 00:00:00
abstract::The cortical projections to neck muscle motoneurons were studied in normal subjects by electrical and magnetic transcranial brain stimulation. After magnetic stimulation with a large coil, motor evoked potentials were present in about 20% of relaxed and 100% of contracting neck muscles. The latency of these responses ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231857
更新日期:1991-01-01 00:00:00