Abstract:
:Dorsomedial frontal cortex (DMFC) was studied in monkeys trained to make visually guided eye or arm movements. Portions of DMFC are involved in the execution of learned, goal-directed behaviors. Many neurons discharge with both eye and hand movements as well as when motor responses are withheld, provided these behaviors are related to the successful execution of the learned task. Similar movements, when carried out at times unrelated to the task, are not accompanied by neuronal activity. Electrical microstimulation produces either arrest of task-related, but not task-unrelated motor acts, or triggers task-related movements. The nature of stimulation elicited responses depends on the task the animal has been trained on and is altered by new training.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Mann SE,Thau R,Schiller PHdoi
10.1007/BF00247300subject
Has Abstractpub_date
1988-01-01 00:00:00pages
460-8issue
3eissn
0014-4819issn
1432-1106journal_volume
69pub_type
杂志文章abstract::Abundant evidence has revealed that social observation could enhance people's norm-enforcement behaviors to norm violators. However, whether such enhancement is strategically reputation-based without changes on awareness of social norms or it is accompanied with strengthened perception of norm violations remains uncle...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-05762-6
更新日期:2020-05-01 00:00:00
abstract::1. An intracellular study on pyramidal tract (PT) neurons in the cat's motor cortex was carried out to examine whether their antidromic activation would be able to induce plastic changes in the efficacy of the synapses situated on their membrane. 2. The experimental paradigm was based on the principles of classical co...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236602
更新日期:1981-01-01 00:00:00
abstract::Our previous study showed an increase in total cholesterol level of the hippocampus after kainate-induced injury, but whether this is further metabolized to neurosteroids is not known. The first step in neurosteroid biosynthesis is the conversion of cholesterol to pregnenolone by the enzyme cytochrome P450 side chain ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-1209-4
更新日期:2008-03-01 00:00:00
abstract::Second-order vestibular neurons of frogs receive converging monosynaptic excitatory and disynaptic excitatory and inhibitory inputs following electrical pulse stimulation of an individual semicircular canal nerve on the ipsilateral side. Here we revealed, in the in vitro frog brain, disynaptic inhibitory postsynaptic ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000544
更新日期:2000-12-01 00:00:00
abstract::In humans, vibration applied to muscle tendons evokes illusory sensations of movement that are usually associated with an excitatory tonic response in muscles antagonistic to those vibrated (antagonist vibratory response or AVR). The aim of the present study was to investigate the neurophysiological mechanisms underly...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050631
更新日期:1999-02-01 00:00:00
abstract::The microtubule associated tau protein becomes hyperphosphorylated in Alzheimer's disease (AD). While hyperphosphorylation promotes neurodegeneration, the cause and consequences of this abnormal modification are poorly understood. As impaired energy metabolism is an important hallmark of AD progression, we tested whet...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5341-0
更新日期:2018-11-01 00:00:00
abstract::Transcranial magnetic stimulation (TMS) causes the corticospinal system to become refractory to subsequent stimuli for up to 200 ms. We examined the phenomenon of paired pulse inhibition with TMS under conditions of rest, ongoing voluntary activation (isometric force generation), and at variable delays following activ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228638
更新日期:1996-04-01 00:00:00
abstract::The present study tested the idea that the visuomotor systems mediating prehension do not have independent access to pictorial cues processed by perceptual mechanisms. Individuals with visual form agnosia, whose perceptual systems are compromised but who have intact visuomotor control, were examined to determine wheth...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005731
更新日期:1997-08-01 00:00:00
abstract::A series of step-tracking experiments was conducted before, during, and after a 3-week space mission to assess the effects of prolonged microgravity on a non-postural motor-control task. In- and post-flight accuracy was affected only marginally. However, kinematic analyses revealed a considerable change in the underly...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050906
更新日期:1999-12-01 00:00:00
abstract::There are a number of studies concerning difference of postural control following left or right hemisphere lesions. Few studies, however, compare the role of the right and left hemisphere in learning new postural tasks. This study aimed to address this question. Twenty patients with hemiparesis after ischemic stroke i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-2091-z
更新日期:2010-04-01 00:00:00
abstract::Multichannel surface EMG recordings of a multiheaded skeletal muscle during cyclic locomotion combined with cineradiography were analysed in a chronic experiment. The resulting detailed two-dimensional activation pattern from the long and lateral triceps brachii heads of the rat during treadmill locomotion were combin...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210100685
更新日期:2001-05-01 00:00:00
abstract::Attention-deficit hyperactivity disorder (ADHD) is a prevalent psychiatric disorder in children that often continues into adulthood. It has been suggested that motor impairments in ADHD are associated with underlying cerebellar pathology. If such is the case, individuals with ADHD should be impaired on motor tasks req...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-4190-8
更新日期:2015-04-01 00:00:00
abstract::Research in the vestibular field has revealed the existence of a central process, called 'velocity storage', that is activated by both visual and vestibular rotation cues and is modified by gravity, but whose functional relevance during natural motion has often been questioned. In this review, we explore spatial orien...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-011-2568-4
更新日期:2011-05-01 00:00:00
abstract::Primary sensory and motor areas of the cerebral cortex contain organised maps of the body. These maps appear to reorganise after damage to the peripheral parts of the sensory or motor systems, so that the cortical representation of undamaged structures expands at the expense of the damaged parts. Several studies in an...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000477
更新日期:2000-08-01 00:00:00
abstract::A database of positron-emission-tomography studies published between January 1993 and November 1996 was created to address several questions regarding the function and connectivity of the human anterior cingulate cortex (ACC). Using this database, we have previously reported on the relationship between behavioural var...
journal_title:Experimental brain research
pub_type: 杂志文章,meta分析
doi:10.1007/s002210000400
更新日期:2000-07-01 00:00:00
abstract::The aim of this study was to analyse the functional impairments caused by chronic median nerve compression at the wrist on hand sensation and manual skill. Hand function was assessed in 11 patients (8 women and 3 men) with severe carpal tunnel syndrome (CTS) and compared with that of an age- and sex-matched control gr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050817
更新日期:1999-09-01 00:00:00
abstract::The activity of subthalamic nucleus neurons related to motor performance was studied in three unrestrained cats operantly conditioned to perform a lever-release movement. The movement was initiated either rapidly after the trigger stimulus (a brief sound) in a simple reaction-time paradigm or after a delay in trials i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228095
更新日期:1996-03-01 00:00:00
abstract::The effect of the intermittency of visual information in the bimanual coordination of an isometric force coordination task was investigated as a function of criterion force level. Eight levels of visual information intermittency (.2-25.6 Hz) were used in blocked fashion at each force level. Participants were required ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4606-8
更新日期:2016-07-01 00:00:00
abstract::Intracellular recording techniques were used to test for cross-modality and topographic convergence among inputs to area 3a of cerebral cortex. Recordings were made within the projection area of group I afferent fibers of the deep radial nerve in barbiturate-anesthetized cats. Epsps were evoked in 90% of neurons (81/9...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236532
更新日期:1985-01-01 00:00:00
abstract::This investigation was designed to study the effects of post-activation depression in different spinal pathways fed by group I afferents available to investigation in human subjects. It was precipitated by a recent investigation in the cat showing that-contrary to the general assumption-post-activation depression is n...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2360-4
更新日期:2005-10-01 00:00:00
abstract::The purposes of this pilot study were to create a model of focal cortical ischemia in Macaca fascicularis and to explore contributions of the reticulospinal system in recovery of reaching. Endothelin-1 was used to create a focal lesion in the shoulder/elbow representation of left primary motor cortex (M1) of two adult...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4390-x
更新日期:2015-11-01 00:00:00
abstract::The time course of local changes of the extracellular space (ES) was investigated by measuring concentration changes of repeatedly injected tetramethylammonium (TMA+) and choline (Ch+) ions for which cell membranes are largely impermeable. After stimulus-induced extracellular [K+] elevations the delta [TMA+] and delta...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236151
更新日期:1980-01-01 00:00:00
abstract::The morphology of neurons in the lateral geniculate nucleus of the rat has been examined in both Golgi impregnated and in horseradish peroxidase (HRP) filled material. Two major classes of neurons are seen in Golgi material which encompass the variety of cells described in previous reports. Cells of one group (class A...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237987
更新日期:1984-01-01 00:00:00
abstract::In this work a statistical study is made of the final outcome of the quantification of the nerve cell labelling in the adult, after prenatal injection of tritiated thymidine. This outcome is presented in the form of histograms which are the superposition of elementary Poisson distributions. A theoretical model, based...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235410
更新日期:1975-01-01 00:00:00
abstract::Several types of continuous human movements comply with the so-called Two-Thirds Power Law (2/3-PL) stating that velocity (V) is a power function of the radius of curvature (R) of the endpoint trajectory. The origin of the 2/3-PL has been the object of much debate. An experiment investigated further this issue by comp...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4569-9
更新日期:2016-06-01 00:00:00
abstract::Although a number of studies have demonstrated state-related dependence of auditory steady-state responses (ASSRs), the investigations assessing trait-related ASSR changes are limited. Five consistently identified major trait dimensions, also referred to as "big five" (Neuroticism, Extraversion, Openness, Agreeablenes...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4494-3
更新日期:2016-03-01 00:00:00
abstract::Recently, responses to looming visual stimuli have been shown to depend on the emotional content of the stimulus. A threatening stimulus is judged to arrive sooner compared to a neutral stimulus, possibly buying the organism time to prepare defensive actions. Here, we explored the underlying mechanism. We found that t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3930-0
更新日期:2014-07-01 00:00:00
abstract::Motoneurones innervating the retractor bulbi muscle in the cat have been identified by retrograde labelling with horseradish peroxidase, by intracellular recording and by intracellular staining with horseradish peroxidase. Their somata are found in an accessory abducens nucleus, analogous to that described in some oth...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239148
更新日期:1979-02-15 00:00:00
abstract::During saccadic eye movements, images of external objects move rapidly across the retina. Small, unpredictable displacements imposed upon a target moving at saccadic velocity were detected with equal accuracy when (1) the retinal image velocity was caused by an eye movement, or (2) when the same velocity was produced ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236664
更新日期:1980-01-01 00:00:00
abstract::Perceived motion may be a stimulus for anticipatory slow eye movements. To test this possibility, the production of anticipatory slow eye movements in humans was studied using apparent motion stimuli. Short range apparent motion was produced with random dot stimuli and the anticipatory slow eye movements were isolated...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247357
更新日期:1989-01-01 00:00:00