Abstract：
:In this work a statistical study is made of the final outcome of the quantification of the nerve cell labelling in the adult, after prenatal injection of tritiated thymidine. This outcome is presented in the form of histograms which are the superposition of elementary Poisson distributions. A theoretical model, based on Probability theory, has been developed explaining the experimental outcome. Studying the final histograms of a defined region, according to this model, we can find out the number and the importance of the constitutive cell generations (chronology). From the graphic study of the percentage of labelled cells and that of the average of grains, the characteristics of the stratification of the neuronic populations/architectony) can be defined. All these notions have been gathered into a new concept: chronoarchitectony. This concept has also been applied to the neocortex. The results show that there is a strong interpenetration of the different cell generations in a given layer. The cortical neuronic production is a continuous phenomenon and there is no correspondence with the discontinuity of the cortical layers.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Bisconte JC,Marty Rdoi
10.1007/BF00235410keywords:
subject
Has Abstractpub_date
1975-01-01 00:00:00pages
37-56issue
1eissn
0014-4819issn
1432-1106journal_volume
22pub_type
杂志文章abstract：:In 15 musicians, cortical DC-potentials were recorded from the scalp before and during the execution of bimanual motor sequences. Subjects (Ss) either tapped with their two index fingers in synchrony (quavers against quavers; "2 against 2") or they tapped quavers against triplets ("2 against 3"). Either the right or t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229320
更新日期：1990-01-01 00:00:00
abstract：:Our goal was to study potential substrates for cortical modulation of vestibular reflexes in the cat. In initial experiments, injections of wheat-germ-agglutinate-horseradish-peroxidase into Deiters' nucleus and the rostral descending nucleus revealed bilateral colonies of retrogradely filled neurons in cortical areas...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050651
更新日期：1999-03-01 00:00:00
abstract：:The properties of the retinal ganglion cell classes in the cuban treefrog Hyla septentrionalis were studied qualitatively and quantitatively. In the superficial layers of the optic tectum three main classes of afferent optic nerve fibers could be distinguished, class-1*, class-3 and class-4 neurons. Hyla displays a mo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00279659
更新日期：1988-01-01 00:00:00
abstract：:The authors inadvertently submitted a wrong figure part for publication. Figure 8b should be as follows. ...
journal_title：Experimental brain research
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00221-018-5429-6
更新日期：2019-01-01 00:00:00
abstract：:To investigate the topographic organization of nociceptive neurons in the caudal medullary reticular formation, the distribution of cells that exhibit c-fos expression was examined following a unilateral noxious facial stimulus: subcutaneous injection of formalin into the vibrissal pad of awake rats. Labelling for Fos...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228014
更新日期：1995-01-01 00:00:00
abstract：:Cortical migration defects are often associated with epilepsy. In mesial temporal lobe epilepsy (MTLE), granule cell dispersion (GCD), a migration defect of dentate granule cells, is frequently observed. Little is known how GCD develops and to which extent it contributes to the development of seizure activity. Since t...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-009-1948-5
更新日期：2010-01-01 00:00:00
abstract：:Objective attempts to characterize postural control in subjects with cerebellar (Cb) pathology have focused primarily on sagittal plane responses to static standing, semi-dynamic standing, and platform perturbation. Repeated, dynamic, functional movement may provide a better opportunity to study the effects of ataxia ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002219900291
更新日期：2000-05-01 00:00:00
abstract：:Descending control is critically important for the generation of locomotor activities. Yet, our understanding of the descending control system of locomotion is limited. We hypothesized that stimulation of the ventrolateral funiculus (VLF) induces rhythmic activity in lumbar neurons that is correlated with locomotor-li...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2816-7
更新日期：2011-09-01 00:00:00
abstract：:Chronic pain and gait variability in a dual-task situation are both associated with higher risk of falling. Executive functions regulate (dual-task) gait variability. A possible cause explaining why chronic pain increases risk of falling in an everyday dual-task situation might be that pain interferes with executive f...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-4039-1
更新日期：2014-11-01 00:00:00
abstract：:Postischemic spontaneous hyperthermia as a complication of occlusion of the middle cerebral artery with an intraluminal filament has been observed by some authors, but many other reports do not discuss this factor. The possible reasons why some of the authors have not seen severe hyperthermia in their experiments incl...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0909-4
更新日期：2002-01-01 00:00:00
abstract：:The present study used a force-matching task to measure how accurately subjects could match a force using different muscle groups. Forces ranging in magnitude from 2 to 10 N were produced and matched by three muscle groups: the elbow flexors, the forearm and hand muscles involved in the palmar prehensile grasp, and th...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-003-1434-4
更新日期：2003-07-01 00:00:00
abstract：:This study investigated the effects of declined accommodation on reading performance in non-native and native languages. Eighteen native Japanese speakers participated: eight presbyopes and ten non-presbyopes. In the experiment, participants were asked to scan, or sequentially read six-word items presented in two-line...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05588-x
更新日期：2019-09-01 00:00:00
abstract：:The efficacy of inhibitory and excitatory intracortical circuits acting on the representation of an intrinsic hand muscle in the primary motor cortex of both hemispheres was measured with paired transcranial magnetic stimuli in right-handed subjects. Both intracortical inhibition (measured with an interstimulus interv...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1696-x
更新日期：2004-03-01 00:00:00
abstract：:Automatic postural responses of leg muscles to the sudden displacement of standing support were investigated under four different conditions of information given to subjects in advance. Results from three groups of subjects were compared: 6 normal subjects, 10 patients with cerebellar disease, and 9 patients with Park...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231777
更新日期：1991-01-01 00:00:00
abstract：:The purposes of this pilot study were to create a model of focal cortical ischemia in Macaca fascicularis and to explore contributions of the reticulospinal system in recovery of reaching. Endothelin-1 was used to create a focal lesion in the shoulder/elbow representation of left primary motor cortex (M1) of two adult...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4390-x
更新日期：2015-11-01 00:00:00
abstract：:The effects of repetitive transcranial stimulation (rTMS) on brain activity remain unknown. In healthy subjects, we studied the effects of rTMS on the duration of the cortical silent period (SP). Repetitive stimuli were delivered with a Cadwell High Speed Magnetic Stimulator and a figure-of-eight coil placed over the ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050661
更新日期：1999-03-01 00:00:00
abstract：:Gabapentin's main clinical use is in the treatment of neuropathic pain where its binding to neuronal alpha-2/delta subunits of voltage-gated calcium channels (VGCCs) is critical to its mechanism of action. Over the past 10 years, there have been several reports of gabapentin also having anti-nausea and anti-emetic eff...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-014-3905-1
更新日期：2014-08-01 00:00:00
abstract：:A series of step-tracking experiments was conducted before, during, and after a 3-week space mission to assess the effects of prolonged microgravity on a non-postural motor-control task. In- and post-flight accuracy was affected only marginally. However, kinematic analyses revealed a considerable change in the underly...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050906
更新日期：1999-12-01 00:00:00
abstract：:Morphometric changes have been studied at the mouse neuromuscular junction (NMJ) as a function of the frequency of stimulation. In vivo stimulation was made at either 10, 25, 50 or 100 Hz. No significant change in the area of NMJ profiles is observed after stimulation. This indicates that stimulation does not change t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237590
更新日期：1986-01-01 00:00:00
abstract：:The morphology of neurons in the lateral geniculate nucleus of the rat has been examined in both Golgi impregnated and in horseradish peroxidase (HRP) filled material. Two major classes of neurons are seen in Golgi material which encompass the variety of cells described in previous reports. Cells of one group (class A...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237987
更新日期：1984-01-01 00:00:00
abstract：:Recently, responses to looming visual stimuli have been shown to depend on the emotional content of the stimulus. A threatening stimulus is judged to arrive sooner compared to a neutral stimulus, possibly buying the organism time to prepare defensive actions. Here, we explored the underlying mechanism. We found that t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3930-0
更新日期：2014-07-01 00:00:00
abstract：:Dual task paradigms can be used to examine the interactions between cognition and the control of posture and gait. Measuring and interpreting changes in dual task performance is challenging, however, because many factors can influence performance. This study examined the effects of instructed focus and walking task di...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2429-6
更新日期：2010-11-01 00:00:00
abstract：:Vibratory stimulation of the neck muscles can elicit illusory drift of a visual target; after vibration stops, motion in the opposite direction is perceived. This motion aftereffect (MAE) could be due to adaptation of proprioceptive mechanisms that encode head orientation, or at a stage where visual and proprioceptive...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0910-7
更新日期：2007-07-01 00:00:00
abstract：:The amyloid precursor protein (APP) has a pivotal role in pathogenesis of Alzheimer's disease (AD) via its beta- and gamma-secretase-derived cleavage products--the A-beta peptides. An alternative processing pathway provided by the alpha-secretase prevents formation of those toxic peptides and gives rise to the neurotr...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-011-2885-7
更新日期：2012-04-01 00:00:00
abstract：:The integrity of the paramedian pontine reticular formation (PPRF) is necessary for the generation of rapid eye movements. The main saccade-related population is of the burst type with latencies between 0 and 40 ms preceding a saccade, and they can be divided into medium- and long-lead burst neurons. Burst neurons hav...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237155
更新日期：1983-01-01 00:00:00
abstract：:Transcranial magnetic stimulation (TMS) applied over the occipital lobe approximately 100 ms after the onset of a stimulus decreases its visibility if it appears in the location of the phosphene. Because phosphenes can also be elicited by stimulation of the parietal regions, we asked if the same procedure that is used...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3888-y
更新日期：2014-06-01 00:00:00
abstract：:Local anesthetic may cause neurotoxicity in developing neurons. In this study, we examined the molecular mechanisms of microRNA-210 (miR-210) in regulating bupivacaine-induced dorsal root ganglia (DRG) neurotoxicity in vitro. Young mouse (P30) DRG explants were cultured in vitro and treated with 5 mM bupivacaine to in...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4513-4
更新日期：2016-04-01 00:00:00
abstract：:Cultured rat hippocampal neurons with short processes were investigated using the whole cell voltage clamp under conditions appropriate for isolating Na+ currents. After incubation of the neuron culture for a period of 15-30 min in 1 mM sodium valproate, several parameters of the Na+ current were changed. The peak Na+...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228395
更新日期：1993-01-01 00:00:00
abstract：:The prefrontal cortex (PFC) plays an important role in several cognitive functions, such as planning, decision making, and social behavior. We previously reported that periodontal sensory input significantly increases PFC activity during the motor task of maintaining occlusal (biting) force. However, the relationships...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05630-y
更新日期：2019-11-01 00:00:00
abstract：:When humans pursue motion stimuli composed of alternating constant velocity segments of randomised duration (RD), they nevertheless initiate anticipatory eye deceleration before stimulus direction changes at a pre-programmed time based on averaging prior stimulus timing. We investigated, in both the time and frequency...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-011-2725-9
更新日期：2011-07-01 00:00:00
