Abstract：
:Morphometric changes have been studied at the mouse neuromuscular junction (NMJ) as a function of the frequency of stimulation. In vivo stimulation was made at either 10, 25, 50 or 100 Hz. No significant change in the area of NMJ profiles is observed after stimulation. This indicates that stimulation does not change the volume of the nerve terminal. There is also no change of the volume density of mitochondria. However, there are significant reductions of the numerical density on area (NA, number/micron2) of the clear vesicles following stimulation at 25, 50 or 100 Hz. The NA of clear vesicles is not further reduced following stimulation at 50 or 100 Hz than after the stimulation at 25 Hz. The numerical density on area of the coated vesicles was significantly increased following the stimulation at 25 Hz and 100 Hz. It is not increased more following stimulation at 50 Hz or 100 Hz than following stimulation at 25 Hz. One possible interpretation of the clear vesicle and the coated vesicle results is that less vesicles are liberated per sec by the NMJ with stimulation at 50 and 100 Hz than at 25 Hz because the action potential may fail to invade some terminal arborizations. The total surface density (i.e. surface of membrane in micron2 per micron3 of nerve terminal) of the clear vesicles, the coated vesicles, the vacuoles and the presynaptic plasma membrane is not changed significantly following stimulation at any frequency. This indicates that there is no net loss of membrane at any of the frequencies investigated.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Tremblay JP,Belhumeur C,Sasseville R,Grégoire Ldoi
10.1007/BF00237590subject
Has Abstractpub_date
1986-01-01 00:00:00pages
638-44issue
3eissn
0014-4819issn
1432-1106journal_volume
61pub_type
杂志文章abstract：:Many studies have demonstrated attenuated verbal working memory (WM) under articulatory suppression. However, performance is not completely abolished, suggesting a less efficient, non-articulatory mechanism for the maintenance of verbal information. The neural causes for the reduced efficiency of such a putative compl...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3770-3
更新日期：2014-02-01 00:00:00
abstract：:Previous research has demonstrated that negative affect influences attentional processes. Here, we investigate whether pre-experimental negative affect predicts a hypervigilant neural response as indicated by increased event-related potential amplitudes in response to neutral and positive visual stimuli. In our study,...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4544-x
更新日期：2016-06-01 00:00:00
abstract：:It is a common experience, immediately after the removal of a cast or a splint, to feel motor awkwardness, which is usually attributed to muscular and joint immobilization. However, the same feeling may also be perceived after a brief period of immobilization. We provide evidence that this last effect stems from chang...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3115-7
更新日期：2012-07-01 00:00:00
abstract：:The afternystagmus that occurs in the dark after gaze fixation during optokinetic stimulation is directed in the opposite direction relative to the previous optokinetic stimulus. The mechanism responsible for such afternystagmus after suppression of optokinetic nystagmus (ASOKN) is unclear. Several hypotheses have bee...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-014-3971-4
更新日期：2014-09-01 00:00:00
abstract：:Previous studies have demonstrated the importance of both kinesthetic and auditory feedback for control of voice fundamental frequency (F0). In the present study, a possible interaction between auditory feedback and kinesthetic feedback for control of voice F0 was tested by administering local anesthetic to the vocal ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1330-z
更新日期：2008-06-01 00:00:00
abstract：:The study assessed the ability of the central nervous system (CNS) to use echoic information from sensory substitution devices (SSDs) to rotate the shoulders and safely pass through apertures of different width. Ten visually normal participants performed this task with full vision, or blindfolded using an SSD to obtai...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3809-5
更新日期：2014-03-01 00:00:00
abstract：:We studied the circuitry between the utricular (UT) nerve and ventral neck motoneurons innervating the longus capitis (LC), a neck flexor muscle, in decerebrate cats. We recorded intracellularly from 63 LC (ipsilateral 37, contralateral 26) motoneurons in C1 and C2 segments. UT nerve stimulation evoked disynaptic, exc...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00233975
更新日期：1994-01-01 00:00:00
abstract：:In two experiments, we examined the effect of selective attention at encoding on repetition priming in normal aging and Alzheimer's disease (AD) patients for objects presented visually (experiment 1) or haptically (experiment 2). We used a repetition priming paradigm combined with a selective attention procedure at en...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1441-6
更新日期：2008-08-01 00:00:00
abstract：:Threshold elevation in the periphery of the visual field as a consequence of repetitive stimulation can be abolished by stimulating a mirror-symmetric position in the contralateral visual half-field. A patient suffering from a congenital malformation of the right superior colliculus did not exhibit threshold elevation...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236761
更新日期：1979-05-02 00:00:00
abstract：:Everyday actions can be characterized by whether they are freely chosen or commanded by external stimuli, and whether they produce pleasant or unpleasant outcomes. To assess how these aspects of actions affect the sense of agency, we asked participants to perform freely selected or instructed key presses which could p...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-017-5112-3
更新日期：2018-01-01 00:00:00
abstract：:A task has been developed to investigate the ability of cats to switch the direction of an ongoing target-reaching forelimb movement with the aid of a visual cue. The cats were standing in front of two horizontal tubes (internal diameter 30 mm; shoulder level) with food. The entrances of the tubes were closed with opa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228841
更新日期：1990-01-01 00:00:00
abstract：:The effect of unilateral vestibular deafferentation (UVD) on the linear vestibulo-ocular reflex (LVOR) was studied in 11 humans an average of 52 months following surgical UVD. Controls consisted of seven healthy age-matched subjects. The LVOR was evoked by directionally random, transient whole body interaural (heave) ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2089-5
更新日期：2005-03-01 00:00:00
abstract：:The arm movement control system often relies on visual feedback to drive motor adaptation and to help specify desired trajectories. Here we studied whether kinematic errors that were indicated with auditory feedback could be used to control reaching in a way comparable with when vision was available. We randomized twe...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-012-3144-2
更新日期：2012-08-01 00:00:00
abstract：:The present study aimed to elucidate the distribution of ferric and ferrous iron in the hippocampus after kainate-induced neuronal injury. A modified Perl's or Turnbull's blue histochemical stain was used to demonstrate Fe3+ and Fe2+ respectively. Very light staining for iron was observed in the hippocampus, in normal...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0971-y
更新日期：2002-03-01 00:00:00
abstract：:Gait is recognized as a key item related to mental function. Anomalous gait in psychotic individuals has been described for the lower extremities, whereas irregularities for upper body dynamics are not described, explained or verified with unbiased methods. Reduced walking velocity and increased somatic tension define...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-012-3184-7
更新日期：2012-09-01 00:00:00
abstract：:Mental practice (MP) is a promising adjuvant to physical practice that involves many of the same mechanisms and takes on many of the same properties as physical practice. This study compared efficacy of a "massed" MP regimen versus a "distributed" MP regimen on upper extremity (UE) motor impairment and functional limi...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-016-4686-5
更新日期：2016-10-01 00:00:00
abstract：:The action of delta-aminovaleric acid (AVA) on the muscle relaxant properties of baclofen, a GABAB receptor agonist, was investigated in two experimental models: (1) the pathologically increased muscle tone of the gastrocnemius muscle in spastic mutant Han-Wistar rats and (2) the Hoffmann (H)-reflex recorded from plan...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247610
更新日期：1988-01-01 00:00:00
abstract：:The developing lateral geniculate complex was excised from fetal albino rats at 18 days of gestation and implanted into the occipital cortex of host animals at 5 days of postnatal age. Groups of host animals were sacrificed at 10, 20 and 30 days following this procedure. The transplant tissue of selected animals was s...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235864
更新日期：1985-01-01 00:00:00
abstract：:Repetitive finger tapping is a well-established clinical test for the evaluation of parkinsonian bradykinesia, but few studies have investigated other finger movement modalities. We compared the kinematic changes (movement rate and amplitude) and response to levodopa during a conventional index finger-thumb-tapping ta...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3491-7
更新日期：2013-06-01 00:00:00
abstract：:Owing to the flexibility and redundancy of neuromuscular and skeletal systems, humans can trace the same hand trajectory in space with various arm configurations. However, the joint trajectories of typical unrestrained movements tend to be consistent both within and across subjects. In this paper we propose a method t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0039-5
更新日期：2005-12-01 00:00:00
abstract：:Cellular relationships between serotonin (5-HT) axons and tyrosine hydroxylase (TH)-containing neurons were examined by combined (3H)5-HT uptake radioautography and TH immunocytochemistry in the medial zona incerta (ZI) of adult rats, 7 and 50 days after an intracerebral injection of 5,7-Dihydroxytryptamine (5,7-DHT)....
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00250592
更新日期：1988-01-01 00:00:00
abstract：:Selective attention is popularly assessed with colour Stroop tasks in which participants name the ink colour of colour words, whilst resisting interference from the natural tendency to read the words. Prior studies hinted that the key brain regions (dorsolateral prefrontal (dlPFC) and anterior cingulate cortex (ACC)) ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2225-3
更新日期：2010-05-01 00:00:00
abstract：:Observing an action activates action representations in the motor system. Moreover, the representations of manipulable objects are closely linked to the motor systems at a functional and neuroanatomical level. Here, we investigated whether action observation can facilitate object recognition using an action priming pa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1953-8
更新日期：2010-01-01 00:00:00
abstract：:It has been argued that through a process of internal 'simulation', we automatically map observed actions directly onto our motor system to facilitate imitation. Instead, here we show that observed actions influence the kinematic parameters of manual responses in a dynamic, context-dependent fashion. Participants obse...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-2089-6
更新日期：2010-04-01 00:00:00
abstract：:The time course of 72-kDa heat-shock protein (hsp72) induction was evaluated by immunoblotting in cerebral cortex, striatum, hippocampus, cerebellum, liver, and kidney of rats subjected to 60-min focal cerebral ischemia following proximal unilateral occlusion of the right middle cerebral artery (MCA). Neurological exa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000564
更新日期：2001-01-01 00:00:00
abstract：:Previous studies have shown that the "synaptic" bodies of mammalian pinealocytes are a heterogeneous group of organelles. Whereas "synaptic" ribbons (SR) exhibit a day/night rhythm with small numbers during daytime and high numbers at night, the so-called "synaptic" spherules (SS) show species-specific differences in ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236214
更新日期：1987-01-01 00:00:00
abstract：:Path integration studies in humans show that we have the ability to accurately reproduce our path in the absence of visual information. It has been suggested that this ability is supported by acceleration signals, as transduced by the otolith organs, which may then be integrated twice to produce path excursion. Vestib...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1072-3
更新日期：2008-01-01 00:00:00
abstract：:It has previously been shown that unilateral ablation of the whole auditory cortex in the cat disrupts the precedence effect, and also interferes with the ability of the normal animal to discriminate in the Y-maze between a single sound on one side and a double sound consisting of a signal on both left and right sides...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237601
更新日期：1978-02-15 00:00:00
abstract：:Our perception of the vertical depends on allocentric information about the visual surrounds, egocentric information about the own body axis and gravicentric information about the pull of gravity. Previous work has documented that some individuals rely strongly on allocentric information, while others do not, and the ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4526-z
更新日期：2016-04-01 00:00:00
abstract：:Erythropoietin (Epo) has neuroprotective and neurotrophic effects and improves cognitive function in animal models of neurodegenerative and neuropsychiatric illness. In humans, weekly Epo administration over 3 months improves cognitive function in schizophrenia. The neural underpinnings and time-course of this effect ...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-007-1102-1
更新日期：2008-01-01 00:00:00
