Abstract：
:Path integration studies in humans show that we have the ability to accurately reproduce our path in the absence of visual information. It has been suggested that this ability is supported by acceleration signals, as transduced by the otolith organs, which may then be integrated twice to produce path excursion. Vestibuloocular responses to linear translations (LVOR), however, show considerable frequency dependence, with substantial attenuation in response to low frequency translational motion. If otolith information were processed similarly by path integration mechanisms, the resulting signal would not be sufficient to account for robust path integration for stimuli typically used in such studies. We hypothesized that such behavior relies upon cognitive skill and transient otolith cues, typically combined with non-directional cues of motion, such as vibration and noise produced by the mechanics apparatus used to produce linear motion. Continuous motion estimation tasks were used to assess translation perception, while eye movement recordings revealed LVOR responses, in 12 normal and 2 vestibulopathic human subjects while riding on a sled designed to specifically minimize non-directional motion cues. In the near absence of such cues, perceptual responses, like the LVOR, showed high-pass characteristics. This implies that otolith signals are not sufficient to support previously observed path integration behaviors, which must be supplemented by non-directional motion cues.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Seidman SHdoi
10.1007/s00221-007-1072-3subject
Has Abstractpub_date
2008-01-01 00:00:00pages
13-29issue
1eissn
0014-4819issn
1432-1106journal_volume
184pub_type
杂志文章abstract：:Successful results obtained by training sessions using optokinetic (OK) stimulations in order to rehabilitate patients with balance disorders motivated this study. The purpose of the study was to measure eye movement parameters and body stabilization during OK stimulation before and after the rehabilitation program. T...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/BF00232446
更新日期：1994-01-01 00:00:00
abstract：:We studied visuomotor processing in the middle (MS) and lateral suprasylvian (LS) cortices of the alert cat by making single cell recordings while the cat was working in a behavioral task requiring visual fixation and visually guided eye movements. We found responses with three different components: visual sensory, sa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF02259125
更新日期：1992-01-01 00:00:00
abstract：:Studies on grasp control underlying manual dexterity in people with Parkinson disease (PD) suggest that anticipatory grasp control is mainly unaffected during discrete tasks using simple two-digit grasp. Nevertheless, impaired hand function during daily activities is one of the most disabling symptoms of PD. As many d...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2179-5
更新日期：2010-05-01 00:00:00
abstract：:Threshold elevation in the periphery of the visual field as a consequence of repetitive stimulation can be abolished by stimulating a mirror-symmetric position in the contralateral visual half-field. A patient suffering from a congenital malformation of the right superior colliculus did not exhibit threshold elevation...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236761
更新日期：1979-05-02 00:00:00
abstract：:The time course of development of visual acuity for square wave gratings was measured behaviourally in a number of cats that were reared in total darkness until they were either 4 (5 cats) or 6 (1 cat) months of age. Less extensive measurements were also made on animals reared in a similar manner until they were eithe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239811
更新日期：1978-04-14 00:00:00
abstract：:Muscle activity patterns in some complex human jaw muscles appear to be task sensitive. However, it is presently uncertain how changes in motor task affect motor unit (MU) behaviour in the human temporalis muscle. In this study, activity was recorded from 40 MUs in the anterior region of the muscle. The lowest sustain...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230303
更新日期：1993-01-01 00:00:00
abstract：:Descending projections from the mesencephalon and superior colliculus to the inferior olive were analyzed by an autoradiographic tracing method. Injections of tritium-labelled leucine were placed in regions which had previously been identified as sources of afferents to the olive. These were located adjacent to the ce...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF01208593
更新日期：1982-01-01 00:00:00
abstract：:Observation of hand movements has been repeatedly demonstrated to increase the excitability of the motor cortical representation of the hand. Little attention, however, has been devoted to its effect on somatosensory processing. Movement execution is well known to decrease somatosensory cortical excitability, a phenom...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2448-3
更新日期：2011-01-01 00:00:00
abstract：:Attention to sensory stimulation modulates behavioural responses and cortical activity. Attention to movement can also modulate motor responses. For example, directing attention away from cued movements can increase reaction times. This study used fMRI to determine where in the motor cortex attention to movement modul...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0905-8
更新日期：2002-01-01 00:00:00
abstract：:In goal-oriented locomotion, healthy adults generate highly stereotyped trajectories and a consistent anticipatory head orienting behaviour, both evidence of top-down, open-loop control. The aim of this study is to describe the typical development of anticipatory orienting strategies and trajectory formation. Our hypo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3495-3
更新日期：2013-05-01 00:00:00
abstract：:In cats the stretch responses of deafferented Ia afferent fibers from gastrocnemius muscle spindles were measured. The response properties were derived by correlating the action potentials to random mechanical stimuli applied to the gastrocnemius muscle. The muscle stretch consisted of band-limited, normally distribut...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235615
更新日期：1985-01-01 00:00:00
abstract：:In classic conditioning, the interstimulus interval (ISI) between the conditioned (CS) and unconditioned (US) stimulus is a critical parameter. The aim of the present experiment was to assess whether, during conditioning, modification of the CS-US interval could reliably produce changes in the functional properties of...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002219900290
更新日期：2000-06-01 00:00:00
abstract：:The stronger anatomo-functional connections of the supplementary motor area (SMA), as compared with premotor area (PM), with regions of the limbic system, suggest that SMA could play a role in the control of movements triggered by visual stimuli with emotional content. We addressed this issue by analysing the modifica...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1346-8
更新日期：2003-03-01 00:00:00
abstract：:Artificial sensations can be produced by direct brain stimulation of sensory areas through implanted microelectrodes, but the perceptual psychophysics of such artificial sensations are not well understood. Based on prior work in cortical stimulation, we hypothesized that perceived intensity of electrical stimulation m...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2254-y
更新日期：2010-06-01 00:00:00
abstract：:The role of kinaesthetic afferences in controlling coupling of voluntary oscillation of the hand and foot, both in-phase and anti-phase, was investigated by modifying the mechanical properties of one of the two segments (the hand) with applied inertial or elastic loads. Loads consisted of a lead disk, rotating coaxial...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210100762
更新日期：2001-07-01 00:00:00
abstract：:Our previous study showed that a fully flexed or extended hand became perceived as an extended or flexed 'phantom' hand as ischemic anesthesia progressed (Inui et al. in J Physiol 589:5775-5784, 2011). Here, we examined what happened if the hand was held in the midposition before and during the anesthesia. Twenty heal...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3040-9
更新日期：2012-05-01 00:00:00
abstract：:The task of sliding a nut from a rod has been used to study manual slowing in old age (Smith et al. in Neurology 53:1458-1461, 1999; Neurobiol Aging 26:883-890, 2005). In this experiment, we sought to determine if the age-related slowing in this task occurs with losses of motor precision, as indicated by the forces ex...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-2030-z
更新日期：2010-03-01 00:00:00
abstract：:Generally, increases in cortical activity go in parallel with negative shifts and decreases with positive shifts of cortical d.c. potentials. The aim of the present investigation was to test the effects of the inhibitory transmitter gamma-aminobutyric acid (GABA) and of GABA receptor agonists on cortical d.c. potentia...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005614
更新日期：1997-03-01 00:00:00
abstract：:Here we aim to evaluate the ability of transcranial direct current stimulation (tDCS), which is applied over Wernicke's area and its right homologue, to influence lexical decisions and semantic priming and establish an involvement for temporo-parietal areas in lexical and semantic processing. Thirty-two subjects (17 w...
journal_title：Experimental brain research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00221-013-3416-5
更新日期：2013-04-01 00:00:00
abstract：:Sequential intraocular grafting of defined areas from fetal rat brain to adult host rats was used to explore the possibility that such double grafts would become interconnected. Norepinephrine- containing neurons of the locus coeruleus were grafted together with either parietal cerebral cortex, hippocampus, or the cau...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236784
更新日期：1979-03-09 00:00:00
abstract：:The aim of this study was to investigate the effects of self-reinnervation of the medial (MG) and lateral gastrocnemius (LG) muscles on joint kinematics of the whole hindlimb during overground walking on surfaces of varying slope in the cat. Hindlimb kinematics were assessed (1) with little or no activity in MG and LG...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0938-8
更新日期：2007-08-01 00:00:00
abstract：:During isometric contractions of the jaw muscles, oscillations in the rectified masseteric EMG record that are coherent with the mandibular force output are evident at ~8 Hz. We have investigated the load dependence of these oscillations under both force and EMG feedback conditions and the extent to which these oscill...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0144-5
更新日期：2006-03-01 00:00:00
abstract：:This study was designed to determine how visual feedback mediates error corrections during reaching. We used visuomotor rotations to dissociate a cursor, representing finger position, from the actual finger location. We then extinguished cursor feedback at different distances from the start location to determine wheth...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1749-x
更新日期：2009-05-01 00:00:00
abstract：:The blood-brain barrier (BBB) arises from epithelial-like tight junctions that virtually cement adjoining capillary endothelium together in the brain microvasculature. Several experimental manipulations have been shown able to increase the permeability of brain capillaries, by altering endothelial cell membrane integr...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005725
更新日期：1997-07-01 00:00:00
abstract：:The aim of this study was to investigate, in healthy subjects, the modulation of amplitude and phase precision of the auditory steady-state response (ASSR) to 40 Hz stimulation in two resting conditions varying in the level of arousal. Previously, ASSR measures have shown to be affected by the level of arousal, but th...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1111-0
更新日期：2007-10-01 00:00:00
abstract：:Recent results on the nature and limits of multisensory enhancement are inconsistent when stimuli are presented across spatial regions. We presented visual, tactile and visuotactile stimuli to participants in two speeded response tasks. Each unisensory stimulus was presented to either the left or right hemispace, and ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2515-9
更新日期：2011-09-01 00:00:00
abstract：:Through an experimental study of the stability properties of the human neuromuscular system while it performs simple point-to-point arm movements, this paper evaluates the concepts of equilibrium and virtual trajectories as a means of executing movement of the arm. Human subjects grasped the instrumented handle of a t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228024
更新日期：1995-01-01 00:00:00
abstract：:Groups of pregnant rats were injected with two successive daily doses of 3H-thymidine from gestational day 12 and 13 (E12+13) until the day before parturition (E21+22) in order to label in their embryos the proliferating precursors of neurons. At 60 days of age the proportion of neurons generated (or no longer labelle...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237506
更新日期：1981-01-01 00:00:00
abstract：:1. An intracellular study on pyramidal tract (PT) neurons in the cat's motor cortex was carried out to examine whether their antidromic activation would be able to induce plastic changes in the efficacy of the synapses situated on their membrane. 2. The experimental paradigm was based on the principles of classical co...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236602
更新日期：1981-01-01 00:00:00
abstract：:Motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS) and transcranial electrical stimulation (TES) of the motor cortex were recorded in separate sessions to assess changes in motor cortex excitability after a fatiguing isometric maximal voluntary contraction (MVC) of the right ankle dorsa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00240963
更新日期：1995-01-01 00:00:00
