Slowing of dexterous manipulation in old age: force and kinematic findings from the 'nut-and-rod' task.

abstract：:The purpose of this study was to determine if recovery of neurologically impaired hand function following isolated motor cortex injury would occur without constraint of the non-impaired limb, and without daily forced use of the impaired limb. Nine monkeys (Macaca mulatta) received neurosurgical lesions of various exte...

journal_title：Experimental brain research

authors： Darling WG,Pizzimenti MA,Rotella DL,Hynes SM,Ge J,Stilwell-Morecraft KS,Vanadurongvan T,McNeal DW,Solon-Cline KM,Morecraft RJ

更新日期：2010-05-01 00:00:00

abstract：:The fate of monoclonal anti-vasopressin antibodies (VP-MAbs) injected in vivo into the paraventricular nucleus (PVN) of the rat brain was studied by immunocytochemistry. Depending on the post survival time, VP-MAbs contained in an ascites fluid were stained at different levels of the VP neurons: the cytoplasm of the P...

journal_title：Experimental brain research

authors： Burlet AJ,Leon-Henri BP,Robert FR,Arahmani A,Fernette BM,Burlet CR

更新日期：1987-01-01 00:00:00

abstract：:To test the functional implications of gaze signals that we previously reported in the dorsal premotor cortex (PMd), we trained two rhesus monkeys to point to visual targets presented on a touch screen while controlling their gaze orientation. Each monkey had to perform four different tasks. To initiate a trial, the m...

journal_title：Experimental brain research

authors： Jouffrais C,Boussaoud D

更新日期：1999-09-01 00:00:00

abstract：:When asked to identify the position of a sound, listeners can report its perceived location as well as their subjective certainty about this spatial judgement. Yet, research to date focused primarily on measures of perceived location (e.g., accuracy and precision of pointing responses), neglecting instead the phenomen...

journal_title：Experimental brain research

authors： Rabini G,Lucin G,Pavani F

更新日期：2020-03-01 00:00:00

abstract：:Endogenous peroxidase-like activity was investigated with a combined light and electron microscopical technique in 15 cats. The lateral cervical nucleus, the dorsal column nuclei, and segments C6 and L5 of the spinal cord were incubated with diaminobenzidine-tetrahydrochloride (DAB) or tetramethylbenzidine (TMB). Afte...

journal_title：Experimental brain research

authors： Svensson BA,Rastad J,Westman J

更新日期：1984-01-01 00:00:00

abstract：:Stimulation of the parietal association cortex as well as the frontal motor cortex elicited clearly extracellular unitary activities or field potentials in the ipsilateral inferior olive in the cat. The parietal-induced responses came out generally at a longer and more variable latency than the frontal-induced ones. T...

journal_title：Experimental brain research

authors： Oka H,Jinnai K,Yamamoto T

更新日期：1979-09-01 00:00:00

abstract：:Discharges of muscle spindle afferents from the soleus muscle were studied in kittens aged 1-21 days and in adult cats. Vibration applied longitudinally to the tendon elicited one impulse for each cycle of vibration over the range 1-200 Hz for the kittens and up to 450 Hz for the adult. Threshold amplitudes were gener...

journal_title：Experimental brain research

authors： Gregory JE,Proske U

更新日期：1988-01-01 00:00:00

abstract：:Experimental neurogenic tumors were induced transplacentally in rats by single injections of ethylnitrosourea (ENU). The resulting primary tumors as well as isogenic transplantation tumor lines and clonal cell lines derived therefrom were examined for their content of the brain specific protein 14-3-2 by a quantitativ...

journal_title：Experimental brain research

authors： Braun M,Grasso A,Wechsler W

更新日期：1976-05-10 00:00:00

abstract：:In healthy subjects, suprathreshold repetitive transcranial magnetic stimulation (rTMS) at frequencies >2 Hz prolongs the cortical silent period (CSP) over the course of the train. This progressive lengthening probably reflects temporal summation of the inhibitory interneurons in the stimulated primary motor cortex (M...

journal_title：Experimental brain research

authors： Cincotta M,Giovannelli F,Borgheresi A,Balestrieri F,Zaccara G,Inghilleri M,Berardelli A

更新日期：2006-06-01 00:00:00

abstract：:Human gait is a complex process in the central nervous system that results from the integrity of various mechanisms, including different cortical and subcortical structures. In the present study, we investigated cortical activity during lower limb movement using EEG. Assisted by a dynamic tilt table, all subjects perf...

journal_title：Experimental brain research

authors： Wieser M,Haefeli J,Bütler L,Jäncke L,Riener R,Koeneke S

更新日期：2010-05-01 00:00:00

abstract：:Cortical spreading depression (CSD) is influenced by brain excitability and is related to neurological diseases, such as epilepsy. In vitro evidence indicates that neuronal electrical activity is potentiated after CSD. Malnutrition can cause electrophysiological changes in the brain, both in animals and in humans. Her...

journal_title：Experimental brain research

authors： de Souza TK,e Silva MB,Gomes AR,de Oliveira HM,Moraes RB,de Freitas Barbosa CT,Guedes RC

更新日期：2011-10-01 00:00:00

abstract：:Local alpha-band synchronization has been associated with both cortical idling and active inhibition. Recent evidence, however, suggests that long-range alpha synchronization increases functional coupling between cortical regions. We demonstrate increased long-range alpha and beta band phase synchronization during sho...

journal_title：Experimental brain research

authors： Doesburg SM,Herdman AT,Ribary U,Cheung T,Moiseev A,Weinberg H,Liotti M,Weeks D,Grunau RE

更新日期：2010-04-01 00:00:00

abstract：:Judgments on laterality of hand stimuli are faster and more accurate when dealing with one's own than others' hand, i.e. the self-advantage. This advantage seems to be related to activation of a sensorimotor mechanism while implicitly processing one's own hands, but not during explicit one's own hand recognition. Here...

journal_title：Experimental brain research

authors： Conson M,Errico D,Mazzarella E,De Bellis F,Grossi D,Trojano L

更新日期：2015-04-01 00:00:00

abstract：:Immunohistochemical double staining for gonadotropin releasing hormone (GnRH) and tyrosine hydroxylase (TH) or glutamic acid decarboxylase (GAD) reveals in the septo-preoptic-diagonal band complex of the rat brain close spatial associations between GnRH-immunoreactive perikarya and TH and GAD immunoreactive fibers. In...

journal_title：Experimental brain research

authors： Jennes L,Stumpf WE,Tappaz ML

更新日期：1983-01-01 00:00:00

abstract：:The mechanisms by which the nervous system coordinates multiple muscles for the control of finger movements are not well understood. One possibility is that groups of muscles may be enlisted into synergies by last-order inputs that project across multiple motor nuclei. In this study we investigated the role that tacti...

journal_title：Experimental brain research

authors： McIsaac TL,Fuglevand AJ

更新日期：2006-10-01 00:00:00

abstract：:The sense of agency is a profoundly important human experience and is strongly linked to volitional action. The importance of this experience is underscored by the fact that many neurological and psychiatric disorders are partially characterized by an abnormal sense of agency (e.g., schizophrenia, anxiety disorders, d...

journal_title：Experimental brain research

authors： Obhi SS,Swiderski KM,Farquhar R

更新日期：2013-09-01 00:00:00

abstract：:The simultaneous presentation of a visual and an auditory stimulus can lead to a decrease in people's ability to perceive or respond to the auditory stimulus. In this study, we investigate the effect that threat has upon this phenomenon, known as the Colavita visual dominance effect. Participants performed two blocks ...

journal_title：Experimental brain research

authors： Van Damme S,Crombez G,Spence C

更新日期：2009-02-01 00:00:00

abstract：:The present experiment investigated the effects of aging on emotional behavior, without concomitant influences from any previous behavioral manipulation apart from weighing the rats. Anxiety-related behaviors were measured in the elevated plus-maze (EPM). Performance in the open field (OF) was also assessed to control...

journal_title：Experimental brain research

authors： Torras-Garcia M,Costa-Miserachs D,Coll-Andreu M,Portell-Cortés I

更新日期：2005-07-01 00:00:00

abstract：:Two experiments were conducted to determine the effects of conditioned circling on the concentrations of dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) within discrete regions of the striatum (STR). The first study assessed the inherent regional distributions of these compounds with ...

journal_title：Experimental brain research

authors： Szostak C,Jakubovic A,Phillips AG,Fibiger HC

更新日期：1989-01-01 00:00:00

abstract：:Efferents originating from the rat medial prefrontal cortex and projecting to diencephalic and mesencephalic structures were analyzed electrophysiologically. The antidromic activation technique was used in order to identify cortical neurons which innervate the medio-dorsal nucleus of the thalamus (MD), lateral habenul...

journal_title：Experimental brain research

authors： Thierry AM,Chevalier G,Ferron A,Glowinski J

更新日期：1983-01-01 00:00:00

abstract：:Abundant evidence has revealed that social observation could enhance people's norm-enforcement behaviors to norm violators. However, whether such enhancement is strategically reputation-based without changes on awareness of social norms or it is accompanied with strengthened perception of norm violations remains uncle...

journal_title：Experimental brain research

authors： Ouyang H,Sun F,Che L,Zhang W,Cheng X,Zheng L

更新日期：2020-05-01 00:00:00

abstract：:Learning in perceptual tasks is typically highly specific to the trained stimulus parameters. However, can learning be specific to a stimulus parameter that is perceptually indistinguishable from another? We assessed this question using a perceived sound location task in which the perceived sound location was created ...

journal_title：Experimental brain research

authors： Sand A,Nilsson ME

更新日期：2014-06-01 00:00:00

abstract：:Previous work has highlighted the role of haptic feedback for manual dexterity, in particular for the control of precision grip forces between the index finger and thumb. It is unclear how fine motor skills involving more than just two digits might be affected, especially given that loss of sensation from the hand aff...

journal_title：Experimental brain research

authors： Miall RC,Rosenthal O,Ørstavik K,Cole JD,Sarlegna FR

更新日期：2019-09-01 00:00:00

abstract：:The effect of unilateral vestibular deafferentation (UVD) on the linear vestibulo-ocular reflex (LVOR) was studied in 11 humans an average of 52 months following surgical UVD. Controls consisted of seven healthy age-matched subjects. The LVOR was evoked by directionally random, transient whole body interaural (heave) ...

journal_title：Experimental brain research

authors： Crane BT,Tian JR,Ishiyama A,Demer JL

更新日期：2005-03-01 00:00:00

abstract：:The microtubule associated tau protein becomes hyperphosphorylated in Alzheimer's disease (AD). While hyperphosphorylation promotes neurodegeneration, the cause and consequences of this abnormal modification are poorly understood. As impaired energy metabolism is an important hallmark of AD progression, we tested whet...

journal_title：Experimental brain research

authors： Ahmad W

更新日期：2018-11-01 00:00:00

abstract：:Rats probe objects with their whiskers and make decisions about sizes, shapes, textures and distances within a few tens of milliseconds. This perceptual analysis requires the processing of tactile high-frequency object components reflecting surface roughness. We have shown that neurons in the barrel cortex of rats enc...

journal_title：Experimental brain research

authors： Ewert TA,Möller J,Engel AK,Vahle-Hinz C

更新日期：2015-10-01 00:00:00

abstract：:Human walking dynamics are typically framed in the context of mechanics and energetics rather than in the context of neuromuscular control. Dynamic walking principles describe one helpful theoretical approach to characterize efficient human walking mechanics over many steps. These principles do not, however, address h...

journal_title：Experimental brain research

authors： Toney ME,Chang YH

更新日期：2013-12-01 00:00:00

abstract：:The adaptation and habituation characteristics produced by the repeated presentation of a moving visual stimulus were studied in single cells in the pigeon's optic tectum. Units located near the surface in the stratum opticum showed little adaptation. However, cells located in deeper layers exhibited varying rates and...

journal_title：Experimental brain research

authors： Woods EJ,Frost BJ

更新日期：1977-03-30 00:00:00

abstract：:The content of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) in motoneurons was studied in four motor pools supplying muscles in the rat hind limb subserving different types of motor activity. The motor pools were identified by retrograde labeling with horseradish peroxidase or fluorophore-conjugated...

journal_title：Experimental brain research

authors： Piehl F,Arvidsson U,Hökfelt T,Cullheim S

更新日期：1993-01-01 00:00:00

abstract：:In order to further our understanding of action-blindsight, four hemianopic patients suffering from visual field loss contralateral to a unilateral occipital lesion were compared to six healthy controls during a double task of verbally reported target detection and saccadic responses toward the target. Three oculomoto...

journal_title：Experimental brain research

authors： Fayel A,Chokron S,Cavézian C,Vergilino-Perez D,Lemoine C,Doré-Mazars K

更新日期：2014-03-01 00:00:00