Abstract：
:Chronic pain and gait variability in a dual-task situation are both associated with higher risk of falling. Executive functions regulate (dual-task) gait variability. A possible cause explaining why chronic pain increases risk of falling in an everyday dual-task situation might be that pain interferes with executive functions and results in a diminished dual-task capability with performance decrements on the secondary task. The main goal of this experiment was to evaluate the specific effects of a cognitive dual task on gait variability in chronic low back pain (CLBP) patients. Twelve healthy participants and twelve patients suffering from CLBP were included. The subjects were asked to perform a cognitive single task, a walking single task and a motor-cognitive dual task. Stride variability of trunk movements was calculated. A two-way ANOVA was performed to compare single-task walking with dual-task walking and the single cognitive task performance with the motor-cognitive dual-task performance. We did not find any differences in both of the single-task performances between groups. However, regarding single-task walking and dual-task walking, we observed an interaction effect indicating that low back pain patients show significantly higher gait variability in the dual-task condition as compared to controls. Our data suggest that chronic pain reduces motor-cognitive dual-task performance capability. We postulate that the detrimental effects are caused by central mechanisms where pain interferes with executive functions which, in turn, might contribute to increased risk of falling.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Hamacher D,Hamacher D,Schega Ldoi
10.1007/s00221-014-4039-1subject
Has Abstractpub_date
2014-11-01 00:00:00pages
3509-13issue
11eissn
0014-4819issn
1432-1106journal_volume
232pub_type
杂志文章abstract：:Several studies have shown that people can catch a ball even if it is visible only during part of its flight. Here, we examine how well they can do so. We measured the movements of a ball and of the hands of both the thrower and the catcher during one-handed underarm throwing and catching. The catcher's sight was occl...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2421-1
更新日期：2010-10-01 00:00:00
abstract：:This research is about the role of categorical and coordinate spatial relations and allocentric and egocentric frames of reference in processing spatial information. To this end, we asked whether spatial information is firstly encoded with respect to a frame of reference or with respect to categorical/coordinate spati...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2857-y
更新日期：2011-10-01 00:00:00
abstract：:A recent study by our group showed that the scaling of reach trajectories to target size is independent of conscious visual awareness of that intrinsic target property (Binsted et al. in Proc Natl Acad Sci USA 104:12669-12672, 2007). The present investigation sought to extend previous work and determine whether uncons...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1385-x
更新日期：2008-07-01 00:00:00
abstract：:After a single adaptation session to prisms with gradually incremented shift magnitude, the prism adaptation aftereffect was measured by open loop mid-sagittal pointing (O) to a visual target without visual feedback. This aftereffect corresponded to the summation of the shift in proprioception, measured by straight ah...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0381-2
更新日期：2006-08-01 00:00:00
abstract：:We investigated the influence of gaze elevation on judging the possibility of passing under high obstacles during pitch body tilts, while stationary, in absence of allocentric cues. Specifically, we aimed at studying the influence of egocentric references upon geocentric judgements. Seated subjects, orientated at vari...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1589-0
更新日期：2009-02-01 00:00:00
abstract：:The present study characterizes expression of calbindin D28K (CB-D28K) and parvalbumin (PV) in ventral forebrain (VFB) grafts placed in the neocortex of adult rats bearing quisqualic acid lesions to the nucleus basalis magnocellularis. Three to nine months after transplantation surgery, rats were killed for in situ hy...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050311
更新日期：1998-02-01 00:00:00
abstract：:Previous studies have used a secondary probe reaction time (RT) task to assess attentional demands of a primary task. The current study used a startling acoustic stimulus (SAS) in a probe RT paradigm to test the hypothesis that attentional resources would be directly related to limitations in response preparation. Par...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4340-7
更新日期：2015-09-01 00:00:00
abstract：:X-ray photography was employed to analyse the postural syndromes following unilateral global and selective lesions of the vestibular apparatus in guinea pigs. Following hemilabyrinthectomy, head rotation in the horizontal plane resulted mainly from rotation of the cervical vertebrae whereas lateral head tilt was due t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00250579
更新日期：1989-01-01 00:00:00
abstract：:The position of the center of gravity (CG) is a reference value that is controlled by the nervous system during the performance of movements. In order to maintain equilibrium, leg movement is preceded by a shift of the CG towards the supporting side. This CG shift is initiated by an early displacement of the center of...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050453
更新日期：1998-07-01 00:00:00
abstract：:Changes in cognition due to age have been associated with falls and reduced standing postural control. Sensory integration is one component of postural control that may be influenced by certain aspects of cognitive functioning. This study investigated associations between measures of cognitive function and sensory int...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5394-0
更新日期：2019-01-01 00:00:00
abstract：:In the original publication of the article, Fig. 3 is incorrect. ...
journal_title：Experimental brain research
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00221-020-05838-3
更新日期：2020-09-01 00:00:00
abstract：:Explant cultures of rat spinal cord, brain stem and cerebellum were used to visualize GABAA-receptors by means of immunohistochemistry. For these studies we have incubated the cultures with the monoclonal antibody bd 17 against the beta-subunit of the GABAA/benzodiazepine/chloride channel complex. In spinal cord cultu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228810
更新日期：1990-01-01 00:00:00
abstract：:We examined the distribution of labeled neurons in the parabigeminal nucleus of the monkey following injections of retrograde fluorescent tracers into the superior colliculus. The extent of the visual field representation included in the injection site was assessed from the location of labeled cells in striate cortex....
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230521
更新日期：1991-01-01 00:00:00
abstract：:Dopamine neurons appear to code an error in the prediction of reward. They are activated by unpredicted rewards, are not influenced by predicted rewards, and are depressed when a predicted reward is omitted. After conditioning, they respond to reward-predicting stimuli in a similar manner. With these characteristics, ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050467
更新日期：1998-08-01 00:00:00
abstract：:EMG responses, vertical and A-P shear forces and kinematics of "automatic postural responses" to unexpected translational perturbations in the headward and tailward directions were studied in cats. Muscles acting on the major joints of the forelimbs and hindlimbs were studied. Movement of the animals in response to pe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238231
更新日期：1983-01-01 00:00:00
abstract：:It has previously been found that in fast point-to-point arm movements, proprioceptive feedback is centrally suppressed at the beginning of movement and is facilitated at a time that is correlated with temporal parameters of the planned movement. Here, we show that this correlation holds when subjects are explicitly i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1967-2
更新日期：2009-10-01 00:00:00
abstract：:When a tracked target is occluded transiently, extraretinal signals are known to maintain smooth pursuit, albeit with a reduced gain. The extent to which extraretinal signals incorporate predictions of time-varying behavior, such as gradual changes in target direction, is not known. Three experiments were conducted to...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0717-y
更新日期：2007-03-01 00:00:00
abstract：:The present study tested the idea that the visuomotor systems mediating prehension do not have independent access to pictorial cues processed by perceptual mechanisms. Individuals with visual form agnosia, whose perceptual systems are compromised but who have intact visuomotor control, were examined to determine wheth...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005731
更新日期：1997-08-01 00:00:00
abstract：:Although it is well known that the corticospinal system exerts more influence over distal (hand and fingers) than proximal (elbow and shoulder) upper limb muscles, differences in the importance of this system for voluntary activation of these muscle groups have not been demonstrated directly. Two investigations were c...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050926
更新日期：1999-12-01 00:00:00
abstract：:The amygdala has been demonstrated to contribute to pain-related behavior and food preference. Here, the effect of pain on food preference and food-matched visual-cue memory, in the presence or absence of a basolateral amygdala (BLA) lesion, has been evaluated using a novel innovative apparatus and protocol. Forty adu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05961-1
更新日期：2020-10-26 00:00:00
abstract：:Cell responses to complex visual patterns such as compositions of broad-band (non-monochromatic) colour areas are presented. Patterns were scanned over the receptive field, and cell response at each point was recorded. "Response patterns" were constructed which display the cell transform of the stimulus pattern. Parvo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239571
更新日期：1982-01-01 00:00:00
abstract：:Anticipatory pursuit is not exclusively based on the recent history of target motion ("temporal anticipation"): it can also use static visual cues ("non-temporal anticipation"). Large non-temporal anticipatory changes of the direction of smooth pursuit are observed when the future trajectory of the target can be infer...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1840-3
更新日期：2009-06-01 00:00:00
abstract：:A wealth of evidence describes the strong positive impact that reward has on motor control at the behavioural level. However, surprisingly little is known regarding the neural mechanisms which underpin these effects, beyond a reliance on the dopaminergic system. In recent work, we developed a task that enabled the dis...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05802-1
更新日期：2020-08-01 00:00:00
abstract：:If horizontal saccades or smooth-pursuit eye movements are made with the line-of-sight at different elevations, the three-dimensional (3D) angular rotation axis of the globe tilts by half the vertical eye eccentricity. This phenomenon is named "half-angle rule" and is a consequence of Listing's law. It was recently fo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050943
更新日期：1999-11-01 00:00:00
abstract：:The importance of the caudal ventrolateral medulla (CVLM) in mediating vagal cardiopulmonary (Bezold-Jarisch reflex) reflex activity was studied in urethane-anaesthetized rats. Unilateral electrolytic lesion of the CVLM markedly attenuated Bezold-Jarisch reflex responses (hypotension and bradycardia) elicited by intra...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230698
更新日期：1989-01-01 00:00:00
abstract：:Neurons responding to deep or cutaneous stimuli are situated in different parts of the ventrobasal complex. Within the cutaneous region elongated clusters of cells with common place and modality properties project to single columns in the somatic sensory cortex. The present study sought to determine to what extent sin...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238583
更新日期：1983-01-01 00:00:00
abstract：:Saccadic latency is composed of separate sensory and motor processing delays. Therefore, any alteration in the sensory processing should effect the saccadic latency. Because the highest density of benzodiazepine (Bz) binding sites is located in cerebral cortex, sensory processing of stimuli in this cortical area is ex...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-2235-8
更新日期：2005-05-01 00:00:00
abstract：:Reports of spatial interactions between current and upcoming elements in a movement sequence could be due to intentional planning of a "global" action sequence (i.e., strategic effects), or to unintentional motor planning arising from merely paying attention to upcoming target objects (i.e., interference effects). The...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4511-6
更新日期：2016-04-01 00:00:00
abstract：:Eye-hand coordination is geometrically complex. To compute the location of a visual target relative to the hand, the brain must consider every anatomical link in the chain from retinas to fingertips. Here we focus on the first three links, studying how the brain handles information about the angles of the two eyes and...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1523-4
更新日期：2003-09-01 00:00:00
abstract：:Unitary discharges of the lateral geniculate nucleus (LGN) were analyzed in anesthetized and paralyzed rats after inactivation of visual cortical areas (VC) by cryoblockade or by depositing a cotton wick soaked in KCl (3 M). The receptive fields were mapped prior to and following the interruption of the cortico-genicu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238152
更新日期：1984-01-01 00:00:00
