Distribution of Fos-like immunoreactivity in the caudal medullary reticular formation following noxious facial stimulation in the rat.

Abstract:

:To investigate the topographic organization of nociceptive neurons in the caudal medullary reticular formation, the distribution of cells that exhibit c-fos expression was examined following a unilateral noxious facial stimulus: subcutaneous injection of formalin into the vibrissal pad of awake rats. Labelling for Fos-like immunoreactivity was present in a somatotopic distribution in a region of the lateral reticular formation adjacent to trigeminal nucleus caudalis, which corresponds approximately to lamina V of the medullary dorsal horn. Labelling in adjacent regions of the reticular formation showed no somatotopy but was predominantly ipsilateral. Contralateral labelling was concentrated ventrolaterally around the lateral reticular nucleus and dorsally near the nucleus of the solitary tract.

journal_name

Exp Brain Res

authors

Mineta Y,Eisenberg E,Strassman AM

doi

10.1007/BF00228014

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

34-8

issue

1

eissn

0014-4819

issn

1432-1106

journal_volume

107

pub_type

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