Abstract:
:An aberrant crossed corticotectal pathway can be generated by removal of one visual cortex and the contralateral superior colliculus from newborn rats. This aberrant crossed corticotectal projection arises from the pyramidal neurons located in layer V of the visual cortex and terminates in a spatially orderly manner in the appropriate laminae of the cortically deafferented contralateral colliculus. Comparable results cannot be reproduced by unilateral collicular lesions alone. The significance of these findings and the possible mechanisms involved in the formation of the aberrant pathway are discussed and compared with the retinotectal system.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Jen LS,Lund RD,Boles Jdoi
10.1007/BF00235562subject
Has Abstractpub_date
1978-11-15 00:00:00pages
405-14issue
3-4eissn
0014-4819issn
1432-1106journal_volume
33pub_type
杂志文章abstract::The aim of the study was to investigate grip-load force regulation in Huntington's disease (HD) patients as compared to control subjects during the performance of a manipulative task that required rhythmical unimanual or bimanual isodirectional/non-isodirectional actions in the sagittal plane. Results showed that the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-001-0992-6
更新日期:2002-04-01 00:00:00
abstract::Adult male rats were injected with 6-hydroxydopamine, either into the lateral brain ventricle or directly into the dorsal hippocampus. They were adrenalectomized 5-7 days later, and following an additional 24 hours, the specific in vitro 3H-corticosterone binding capacity of dorsal hippocampal slices was determined by...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237156
更新日期:1983-01-01 00:00:00
abstract::It has been suggested that the deficit in understanding others' intention in autism depends on a malfunctioning of the mirror system. This malfunction could be due either to a deficit of the basic mirror mechanism or to a disorganization of chained action organization on which the mirror understanding of others' inten...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1578-3
更新日期:2009-01-01 00:00:00
abstract::We investigated how neurons in the different motor areas of the frontal lobe reflect the movement dynamics, and how their neuronal activity undergoes plastic changes when monkeys adapt to perturbing forces (they learn new dynamics). Here we describe the results obtained in the dorsal premotor area (PMd) and ventral pr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-0074-2
更新日期:2006-01-01 00:00:00
abstract::The effects of left and right alignment on the Ebbinghaus illusion were investigated in three experiments. In Experiment 1, the Ebbinghaus illusion was presented on the left or right side, and the points of subjective equality (PSE) were measured. Only the central disk of the figure with small inducers was perceived l...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5168-8
更新日期:2018-04-01 00:00:00
abstract::Reduced short-interval intracortical inhibition (SICI) is reported in Parkinson's disease (PD) and is considered to reflect abnormal GABAergic inhibitory system of the primary motor cortex in PD. We have recently shown, however, that SICI using anterior-posterior directed currents in the brain was normal in focal dyst...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2829-2
更新日期:2011-10-01 00:00:00
abstract::We measured the amount of information transmitted by the direction of two-dimensional (2-D) arm movements of human subjects, and by neuronal populations in the motor cortex and area 5 of monkeys. We also compared the information transmitted by a motor cortical population when the predictability of the direction of mov...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247577
更新日期:1988-01-01 00:00:00
abstract::A model of global hypoxia during Caesarean-section (C-section) birth has been widely used to study long-term effects of birth hypoxia on central nervous system (CNS) function. However, the actual degree of CNS and systemic hypoxia produced by the birth insult in this model has never been characterised. Additionally, t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002219900305
更新日期:2000-04-01 00:00:00
abstract::The eyeblink reflex is one of the most extensively studied behaviors in mammals. The active downward force that causes lid closure is controlled by the orbicularis oculi (OO) muscle. To augment our studies on the neurophysiology and plasticity of the rat eyeblink circuit, here we present the first anatomical paper to ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005729
更新日期:1997-08-01 00:00:00
abstract::The efficacy of inhibitory and excitatory intracortical circuits acting on the representation of an intrinsic hand muscle in the primary motor cortex of both hemispheres was measured with paired transcranial magnetic stimuli in right-handed subjects. Both intracortical inhibition (measured with an interstimulus interv...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1696-x
更新日期:2004-03-01 00:00:00
abstract::The presence of after-effects in adaptation tasks implies that an existing internal model has been updated. Previously, we showed that although observers adapted to a visuomotor perturbation, they did not show after-effects. In this experiment, we tested 2 further observer groups and an actor group. Observers were now...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2996-1
更新日期:2012-04-01 00:00:00
abstract::In four monkeys with long-standing partial ablation of the striate cortex pellets of horseradish peroxidase were placed in either the striate cortex immediately adjacent to the ablation, or in the extrastriate cortex of the ventral prelunate gyrus, i.e. in visual area V4. We examined the dorsal lateral geniculate nucl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00249914
更新日期:1989-01-01 00:00:00
abstract::During cerebral neocortical development, excitatory neurons are generated from radial glial cells in the ventricular zone (VZ) or from secondary progenitor cells in the subventricular zone (SVZ); these neurons then migrate toward the pial surface. We have observed that post-mitotic neurons generated directly in the VZ...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-011-2933-3
更新日期:2012-01-01 00:00:00
abstract::Long-range tactile masking has been reported between mirror symmetric body locations. This suggests a general principle of contralateral inhibition between corresponding points on each side of the body that may serve to enhance distinguishing touches on the two halves of the body. Do such effects occur before or after...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4485-4
更新日期:2016-02-01 00:00:00
abstract::The repetition of muscle contractions is likely to generate fatigue which can provoke alterations of postural control. Regulatory mechanisms can be triggered to counteract these alterations. However, these mechanisms would occur only when fatigue is induced through voluntary (VOL) contractions and not with electricall...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5418-9
更新日期:2019-02-01 00:00:00
abstract::The objective of this study was to define cortical and subcortical structures activated during both active and passive movements of the ankle, which have a fundamental role in the physiology of locomotion, to improve our understanding of brain sensorimotor integration. Sixteen healthy subjects, all right-foot dominant...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2335-5
更新日期:2005-09-01 00:00:00
abstract::In the thalamic reticular nucleus (TR) of the rat a cluster of neurons has been located which receives auditory inputs and acts as a source of inhibition for relay neurons of the medial geniculate nucleus (MG). These TR neurons (auditory thalamic reticular neurons; A-TR neurons) showed a repetitive burst of grouped di...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238784
更新日期:1983-01-01 00:00:00
abstract::Second-order vestibular neurons of frogs receive converging monosynaptic excitatory and disynaptic excitatory and inhibitory inputs following electrical pulse stimulation of an individual semicircular canal nerve on the ipsilateral side. Here we revealed, in the in vitro frog brain, disynaptic inhibitory postsynaptic ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000544
更新日期:2000-12-01 00:00:00
abstract::The tendency to generate head movements during saccades varies from person to person. Head movement tendencies can be measured as subjects fixate sequences of illuminated targets, but the extent to which such measures reflect eye-head coupling during more natural behaviors is unknown. We quantified head movement tende...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1534-2
更新日期:2008-12-01 00:00:00
abstract::Push-pull cannulae were inserted into both medial and lateral banks of the suprasylvian sulcus and used for local perfusion with artificial extracellular fluid (aECF). Electrical stimulations of regions of cortex projecting to the lateral suprasylvian area (LSA) were accompanied by enhanced levels of release of excita...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235323
更新日期:1985-01-01 00:00:00
abstract::The cerebrovascular consequences of the gentle restraint commonly used for the measurement of local cerebral blood flow (LCBF) in conscious rats has been tested by using two drugs, propranolol and diazepam. Propranolol induced small LCBF decreases in 7 structures suggesting that the cerebral circulation was partially ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235660
更新日期:1986-01-01 00:00:00
abstract::Two superimposed gratings, which differ in orientation and move independently, combine into a coherently moving plaid if the component gratings are similar. The effect on the plaid motion percept of the addition of texture to each grating was investigated. The texture disambiguates the motion of each component grating...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228400
更新日期:1993-01-01 00:00:00
abstract::Insulin-like growth factor-1 (IGF-1) is an endogenous peptide transported across the blood brain barrier that is protective in several brain injury models, including an acute animal model of Parkinson's disease (PD). Motor deficits in PD are due largely to the progressive loss of nigrostriatal dopaminergic neurons. Th...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4572-1
更新日期:2016-07-01 00:00:00
abstract::The goal of this study was to determine the effect of changes in core body temperature on the resting discharge rate and sensitivity of vestibular-nerve afferents. Extracellular recordings were made from vestibular-nerve afferents innervating the semicircular canals in anesthetized C57BL/6 mice maintained at a core bo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-2015-y
更新日期:2010-01-01 00:00:00
abstract::The thalamic reticular nucleus (RTN) exerts an inhibitory influence upon the dorsal thalamus. During wakefulness and arousal, RTN neurons fire tonically, whereas during slow-wave sleep they fire rhythmic high frequency bursts. The effects produced by RTN inhibition upon the activity of dorsal thalamic neurons will the...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227192
更新日期:1994-01-01 00:00:00
abstract::It has previously been shown that light contact with the finger tip on a fixed surface reduces centre of pressure (CoP) fluctuations in the frontal plane when standing in an unstable posture with the feet in line (tandem Romberg stance). Positive cross-correlations between horizontal finger forces and CoP fluctuations...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050711
更新日期:1999-04-01 00:00:00
abstract::Proprioceptive input arising from torsional body movements elicits small reflexive eye movements. The functional relevance of these eye movements is still unknown so far. We evaluated their slow components as a function of stimulus frequency and velocity. The horizontal eye movements of seven adult subjects were recor...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050418
更新日期:1998-06-01 00:00:00
abstract::Immunohistochemical double staining for gonadotropin releasing hormone (GnRH) and tyrosine hydroxylase (TH) or glutamic acid decarboxylase (GAD) reveals in the septo-preoptic-diagonal band complex of the rat brain close spatial associations between GnRH-immunoreactive perikarya and TH and GAD immunoreactive fibers. In...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238235
更新日期:1983-01-01 00:00:00
abstract::This study addressed the anticonvulsant effects of repeated administration of phenytoin, carbamazepine, phenobarbital, valproate, and ethosuximide in kindled guinea-pigs in order to further substantiate this novel model of partial seizures for the screening of future anticonvulsant drugs. Behavioral toxic effects were...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0716-z
更新日期:2007-03-01 00:00:00
abstract::Peripheral sensory-motor neuropathy is one of the most frequent side effects of vincristine (VCR) administration, which often limits its usefulness in the treatment of a wide range of neoplastic diseases. The purpose of this work is to study VCR neurotoxicity in experimental animals from clinical, electrophysiological...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0499-2
更新日期:2006-08-01 00:00:00