Abstract:
:During cerebral neocortical development, excitatory neurons are generated from radial glial cells in the ventricular zone (VZ) or from secondary progenitor cells in the subventricular zone (SVZ); these neurons then migrate toward the pial surface. We have observed that post-mitotic neurons generated directly in the VZ accumulated just above the VZ with a multipolar morphology, while secondary progenitor cells having a long ascending process left the VZ faster than the post-mitotic neurons. Recent observations of human developing neocortex have revealed the existence of radial glia-like progenitors (oRG cells) in the SVZ. This type of progenitor was first thought to be human specific; however, similar cells have also been found in mouse neocortex, and the morphology of these cells resembled that of some of the secondary progenitor cells that we had previously observed, suggesting the existence of a common architecture for the developing neocortex among mammals. In this review, we discuss the nature of the SVZ and its similarities and differences between humans and mice.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Tabata H,Yoshinaga S,Nakajima Kdoi
10.1007/s00221-011-2933-3subject
Has Abstractpub_date
2012-01-01 00:00:00pages
161-8issue
2eissn
0014-4819issn
1432-1106journal_volume
216pub_type
杂志文章,评审abstract::Growing evidence suggests that blind subjects outperform the sighted on certain tactile discrimination tasks depending on cutaneous inputs. The purpose of this study was to compare the performance of blind (n = 14) and sighted (n = 15) subjects in a haptic angle discrimination task, depending on both cutaneous and pro...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1327-7
更新日期:2008-06-01 00:00:00
abstract::The dual visuomotor channel theory proposes that prehension consists of a Reach that transports the hand in relation to an object's extrinsic properties (e.g., location) and a Grasp that shapes the hand to an object's intrinsic properties (e.g., size and shape). In central vision, the Reach and the Grasp are integrate...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3945-6
更新日期:2014-09-01 00:00:00
abstract::We have reported previously that intracranial application of near-infrared light (NIr) reduces clinical signs and offers neuroprotection in a subacute MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) monkey model of Parkinson's disease. In this study, we explored whether NIr reduces the gliosis in this animal model...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4720-7
更新日期:2016-11-01 00:00:00
abstract::Reflexive attentional shift in response to another individual's gaze direction has been reported, but it remains unknown whether this process can occur subliminally. We investigated this issue using facial stimuli consisting of drawings (Experiment 1) and photographs (Experiment 2). The gaze direction was expressed by...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-1025-x
更新日期:2007-10-01 00:00:00
abstract::Single unit recording from trained rhesus monkeys demonstrate that the activity of the prelunate cortex is enhanced when a visual stimulus becomes a target of saccadic eye movement. As a rule, the enhancement is spatially selective: it does not occur if the animal makes an eye movement away from, rather than towards t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237333
更新日期:1981-01-01 00:00:00
abstract::The effects of an opioid receptor antagonist, naloxone (NAL), were studied on the changes in pituitary hormone secretion induced by emotional stress. Male Wistar rats were trained with tone stimuli paired with electric footshocks and tested with the tone and environmental cue signals for emotional stress of fear acqui...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230100
更新日期:1990-01-01 00:00:00
abstract::The afternystagmus that occurs in the dark after gaze fixation during optokinetic stimulation is directed in the opposite direction relative to the previous optokinetic stimulus. The mechanism responsible for such afternystagmus after suppression of optokinetic nystagmus (ASOKN) is unclear. Several hypotheses have bee...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-014-3971-4
更新日期:2014-09-01 00:00:00
abstract::Several recent studies indicate that saccades elicited in the absence of a visual target are slower than visually-guided movements of the same size. In addition, we have shown earlier that the slower saccades observed in two different paradigms had more asymmetrical (skewed) velocity profiles. Recently, it has been re...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00253624
更新日期:1989-01-01 00:00:00
abstract::In the cat it is known that the distribution and modulation of the so-called P2 responses are similar, irrespective of whether they are obtained with electrodes implanted in the different skin areas or in the various leg muscles. In man it is known that the specific stimulation of cutaneous afferents from different pa...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1366-4
更新日期:2003-04-01 00:00:00
abstract::Recent studies have demonstrated that dyslexia is associated with deficits in the temporal encoding of sensory information. While most previous studies have focused on information processing within a single sensory modality, it is clear that the deficits seen in dyslexia span multiple sensory systems. Surprisingly, al...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-005-2387-6
更新日期:2005-10-01 00:00:00
abstract::Stimulation of cutaneous foot afferents has been shown to evoke a facilitation of the tibialis anterior (TA) EMG-activity at a latency of 70-95 ms in the early and middle swing phase of human walking. The present study investigated the underlying mechanism for this facilitation. In those subjects in whom it was possib...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050600
更新日期:1999-01-01 00:00:00
abstract::Sequential intraocular grafting of defined areas from fetal rat brain to adult host rats was used to explore the possibility that such double grafts would become interconnected. Norepinephrine- containing neurons of the locus coeruleus were grafted together with either parietal cerebral cortex, hippocampus, or the cau...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236784
更新日期:1979-03-09 00:00:00
abstract::Joint stiffness measurements during small transient perturbations have suggested that stiffness during movement is different from that observed during posture. These observations are problematic for theories like the classical equilibrium point hypothesis, which suggest that desired trajectories during movement are en...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000598
更新日期:2001-02-01 00:00:00
abstract::The goal of this study was to determine the effect of changes in core body temperature on the resting discharge rate and sensitivity of vestibular-nerve afferents. Extracellular recordings were made from vestibular-nerve afferents innervating the semicircular canals in anesthetized C57BL/6 mice maintained at a core bo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-2015-y
更新日期:2010-01-01 00:00:00
abstract::The ventral part of the third visual cortical complex, the ventral posterior area (VP) or V3v, is located between the ventral half of visual areas V2 and V4. Because of its location and the physiological properties of its neurons, VP has been considered to be involved in the ventral stream visual areas. The ventral st...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1698-8
更新日期:2004-03-01 00:00:00
abstract::The aim of the present study was to assess the effects of dopaminergic medication on the selection-for-action mechanisms in Parkinson's disease (PD). PD subjects were tested after not having taken medication for at least 12 h ("Off' state) and then retested 1-2 h after medication ("On" state). A three-dimensional kine...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210000510
更新日期:2000-11-01 00:00:00
abstract::The nature of spontaneous unitary activity of rat neocortex was investigated during slow wave sleep and urethane anaesthesia. Neurones in layer IV and V locations fired in a burst-pause pattern at a low burst repetition rate (0.5-4 per second) during both stage 3/4 sleep and urethane anaesthesia. Occasionally an alter...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237474
更新日期:1986-01-01 00:00:00
abstract::The spatial and temporal coupling between the hands is known to be very robust during movements which use homologous muscles (in-phase or symmetric movements). In contrast, movements using nonhomologous muscles (antiphase or asymmetric movements) are less stable and exhibit a tendency to undergo a phase transition to ...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/s00221-003-1496-3
更新日期:2003-08-01 00:00:00
abstract::Rats with unilateral or bilateral partial section of the fornix were impaired on an eight arm radial maze task. Neurochemical analysis of hippocampal tissue four weeks after the lesions revealed a 50% reduction of choline acetyltransferase (ChAT) activity. The cholinergic marker was correlated negatively with the numb...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229009
更新日期:1992-01-01 00:00:00
abstract::Insulin-like growth factor-1 (IGF-1) is an endogenous peptide transported across the blood brain barrier that is protective in several brain injury models, including an acute animal model of Parkinson's disease (PD). Motor deficits in PD are due largely to the progressive loss of nigrostriatal dopaminergic neurons. Th...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4572-1
更新日期:2016-07-01 00:00:00
abstract::Stimulation of the caudal raphe nuclei alters visceral functions. The caudal raphe nuclei project to the nucleus of the solitary tract, which receives the central terminations of vagal afferents and plays an important role in the central integration of autonomic activities. The caudal raphe nuclei also project to the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00241358
更新日期:1995-01-01 00:00:00
abstract::Four experiments were performed with macaque monkeys (rhesus, Macaca mulatta, and cynomolgus, M. fascicularis). In experiment 1 six rhesus monkeys learned pre-operatively to perform delayed matching-to-sample, with complex naturalistic scenes as the stimulus material. Three of these monkeys then received bilateral abl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228977
更新日期:1994-01-01 00:00:00
abstract::Weight illusions--where one object feels heavier than an identically weighted counterpart--have been the focus of many recent scientific investigations. The most famous of these illusions is the 'size-weight illusion', where a small object feels heavier than an identically weighted, but otherwise similar-looking, larg...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-014-3926-9
更新日期:2014-06-01 00:00:00
abstract::1. The somatic location and axonal projections of inhibitory vestibular nucleus neurons activated by the horizontal semicircular canal nerve (HCN) were studied in anesthetized cats. Cats were anesthetized with ketamine hydrochloride and pentobarbital sodium. 2. Intracellular recordings were obtained from 11 neck exten...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231035
更新日期:1991-01-01 00:00:00
abstract::Discrimination learning can cause improved and worsened ability to perceive differences. This subsequently affects how stimuli are associated with meanings and behaviors. Here, human listeners were trained with frequency-modulated (FM) tonal sweeps (500-1000 Hz) in a paradigm where one FM rate (8.29 octaves per second...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4866-3
更新日期:2017-04-01 00:00:00
abstract::Vigilance is the ability to sustain attention to information for prolonged periods of time, particularly in environments where critical signals may be rare. Recent research in the domain of mind-wandering has suggested that processes associated with mind-wandering may underpin the typical decline in vigilance task per...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5438-5
更新日期:2019-02-01 00:00:00
abstract::Both human and animal research indicate that rapid eye movement sleep (REM) plays an important role in the processing of emotional information. REM is altered after fear conditioning in rats, but this alteration can be mitigated by exposure to a naïve conspecific. In addition, both the housing condition (isolated vs p...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-3828-x
更新日期:2014-05-01 00:00:00
abstract::The results of this study show that the different receptive fields of multisensory neurons in the cortex of the cat anterior ectosylvian sulcus (AES) were in spatial register, and it is this register that determined the manner in which these neurons integrated multiple sensory stimuli. The functional properties of mul...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227844
更新日期:1992-01-01 00:00:00
abstract::In the present article, we summarize the recent progress on investigating the mechanism of corticofugal modulation on the auditory thalamus of mammals excluding the bat as it has a specialized auditory system. The article comprises: (1) a review of the anatomy and physiology of the auditory thalamus, and a discussion ...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-003-1680-5
更新日期:2003-12-01 00:00:00
abstract::A database of positron-emission-tomography studies published between January 1993 and November 1996 was created to address several questions regarding the function and connectivity of the human anterior cingulate cortex (ACC). Using this database, we have previously reported on the relationship between behavioural var...
journal_title:Experimental brain research
pub_type: 杂志文章,meta分析
doi:10.1007/s002210000400
更新日期:2000-07-01 00:00:00