Abstract:
:During cerebral neocortical development, excitatory neurons are generated from radial glial cells in the ventricular zone (VZ) or from secondary progenitor cells in the subventricular zone (SVZ); these neurons then migrate toward the pial surface. We have observed that post-mitotic neurons generated directly in the VZ accumulated just above the VZ with a multipolar morphology, while secondary progenitor cells having a long ascending process left the VZ faster than the post-mitotic neurons. Recent observations of human developing neocortex have revealed the existence of radial glia-like progenitors (oRG cells) in the SVZ. This type of progenitor was first thought to be human specific; however, similar cells have also been found in mouse neocortex, and the morphology of these cells resembled that of some of the secondary progenitor cells that we had previously observed, suggesting the existence of a common architecture for the developing neocortex among mammals. In this review, we discuss the nature of the SVZ and its similarities and differences between humans and mice.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Tabata H,Yoshinaga S,Nakajima Kdoi
10.1007/s00221-011-2933-3subject
Has Abstractpub_date
2012-01-01 00:00:00pages
161-8issue
2eissn
0014-4819issn
1432-1106journal_volume
216pub_type
杂志文章,评审abstract::The cerebral representation of space depends on the integration of many different sensory inputs. The vestibular system provides one such input and its dysfunction can cause profound spatial disorientation. Using positron emission tomography (PET), we measured regional cerebral perfusion with various vestibular stimul...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/BF00241421
更新日期:1994-01-01 00:00:00
abstract::In four monkeys with long-standing partial ablation of the striate cortex pellets of horseradish peroxidase were placed in either the striate cortex immediately adjacent to the ablation, or in the extrastriate cortex of the ventral prelunate gyrus, i.e. in visual area V4. We examined the dorsal lateral geniculate nucl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00249914
更新日期:1989-01-01 00:00:00
abstract::Responses to pure visual stimuli and visual-vestibular interactions similar to those reported in other vertebrates were found in single vestibular nucleus neurons in cat. Contrary to prevailing hypotheses, the cerebellum is not an essential part of the pathway mediating these visual responses. ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239555
更新日期:1978-08-15 00:00:00
abstract::The effects of degrading retinal image velocity information on suppression of the vestibulo-ocular reflex have been assessed through tachistoscopic presentation of target sources in man. Subjects were required to fixate a head-fixed display during exposure to a 0.5 Hz sinusoidal angular oscillation of the head at +/- ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239187
更新日期:1983-01-01 00:00:00
abstract::In three monkeys made hemianopic by unilateral striate cortical ablation, in one normal monkey and in a human hemianope (GY), we measured reaction times to chromatic targets presented in the normal hemifield as a function of prior chromatic primes in the blind field. The first of our three tasks showed an unspecific p...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1521-6
更新日期:2003-09-01 00:00:00
abstract::During the flight of Spacelab-1 a series of vestibular experiments was performed on the crew by a group of European investigators. Control experiments were carried out on the same subjects pre- and postflight. The tests included caloric stimulation of the ears, threshold measurements of response to linear acceleration...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237739
更新日期:1986-01-01 00:00:00
abstract::The acquisition of co-ordination between posture and movement was investigated in human subjects performing a load lifting task. Sitting subjects held their left (postural) forearm in a horizontal position while supporting a 1 kg load via an electromagnet. Perturbation of the postural forearm position consisted of the...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00274991
更新日期:1989-01-01 00:00:00
abstract::The differential distribution of glutamate (Glu), aspartate (Asp), glycine (Gly), gamma-aminobutyric acid (GABA) and taurine (Tau) was investigated in the cat's perihypoglossal nuclei. Serial semi-thin (0.5 micron) sections through the perihypoglossal nuclei were incubated with antisera raised against the mentioned am...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228906
更新日期:1989-01-01 00:00:00
abstract::The mechanisms by which the nervous system coordinates multiple muscles for the control of finger movements are not well understood. One possibility is that groups of muscles may be enlisted into synergies by last-order inputs that project across multiple motor nuclei. In this study we investigated the role that tacti...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0643-z
更新日期:2006-10-01 00:00:00
abstract::The aim of this study was to examine how adults processed common fractions with common numerators under two distinct conditions. Whereas participants were presented with only common fractions in a "simple" condition, a "complex" condition involved the random presentation of common fractions as well as decimal fraction...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-011-2969-4
更新日期:2012-03-01 00:00:00
abstract::We applied vibration at various rates to the biceps tendon of a passive, restrained arm in normal human subjects and measured its effect on the perception of forearm position and the perception of forearm velocity. The disturbances of limb position perception and limb velocity perception depended on the vibration rate...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00269450
更新日期:1987-01-01 00:00:00
abstract::While mechanisms of orienting attention in unilateral spatial neglect (USN) have frequently been studied in the visual domain, these mechanisms remain relatively unexplored in the auditory domain. Our first goal was to replicate Spence and Driver's (J Exp Psychol Hum 22:1005-1030, 1994) results with a virtual reality ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4691-8
更新日期:2016-10-01 00:00:00
abstract::A strong subjective tendency exists for simultaneous sound frequencies forming an harmonic series (integer multiples of the fundamental) to "group" together into a unified auditory percept whose pitch is similar to that of the fundamental. The aim of the study was to determine whether cortical auditory evoked potentia...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-003-1482-9
更新日期:2003-06-01 00:00:00
abstract::We investigated the post-train effects of repetitive transcranial magnetic stimulation (rTMS) on motor evoked potential (MEP) size and cortical silent period (SP) duration. rTMS was delivered over the primary motor cortex in trains of 5, 10, 20, 40 and 60 stimuli in normal subjects at rest and in trains of 5, 10 and 2...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0638-9
更新日期:2007-02-01 00:00:00
abstract::Shape is an inherent property of objects existing in both vision and touch but not audition. Can shape then be represented by sound artificially? It has previously been shown that sound can convey visual information by means of image-to-sound coding, but whether sound can code tactile information is not clear. Blindfo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2178-6
更新日期:2010-05-01 00:00:00
abstract::In walking cats decerebrated at the premammillary level, single neurone activity of Purkinje cells (P-cells) with long corticofugal axons was recorded in the cerebellar vermis. The P-cells (N = 145) were identified as they showed spontaneous simple and complex spikes and also antidromic activation from Deiters' nucleu...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238886
更新日期:1981-01-01 00:00:00
abstract::Changes in cognition due to age have been associated with falls and reduced standing postural control. Sensory integration is one component of postural control that may be influenced by certain aspects of cognitive functioning. This study investigated associations between measures of cognitive function and sensory int...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5394-0
更新日期:2019-01-01 00:00:00
abstract::Excitation of dorsal neck motoneurones evoked by electrical stimulation of primary trigeminal afferents in the Gasserian ganglion has been investigated with intracellular recording from alpha-motoneurones in the cat. Single stimulation in the Gasserian ganglion ipsi- and contralateral to the recording side evoked exci...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227964
更新日期:1992-01-01 00:00:00
abstract::The uptake of L-glutamate was studied in astrocytes cultured from different brain areas of newborn rats as well as in two different cultures of neurons obtained from mouse brain. Both astrocytes and neurons exhibited high-affinity glutamate uptake with Km values ranging from 34 microM to 82 microM. Vmax values for ast...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239385
更新日期:1982-01-01 00:00:00
abstract::Recently, it has been reported that grasping with the left hand is more vulnerable to visual size illusions than grasping with the right hand. The present study investigated whether this increased sensitivity of the left hand for visual context extends to reaching. Left- and right-handed participants reached for targe...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2214-6
更新日期:2010-05-01 00:00:00
abstract::The study explores the bottom-up attentional consequences of episodic memory retrieval. Individuals studied words (Experiment 1) or pictures (Experiment 2) presented on the left or on the right of the screen. They then viewed studied and new stimuli in the centre of the screen. One-second after the appearance of each ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-008-1548-9
更新日期:2009-01-01 00:00:00
abstract::Electrical stimulation with repetitive pulses (6/sec) was applied to the internal medullary lamina and produced tonic contraversive turning movements of eyes and head which were associated with recruiting responses in the visual cortex. Optical gratings of a spatial frequency of 0.5 c/deg which alternated with diffuse...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00234015
更新日期:1976-06-18 00:00:00
abstract::The primary objective of this study was to explore why preischemic hypoglycemia, which restricts tissue acidosis during the ischemic insult, does not ameliorate cell damage incurred as a result of transient ischemia. The question arose whether hypoglycemia (plasma glucose concentration 2-3 mM) delays resumption of ext...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00233036
更新日期:1995-01-01 00:00:00
abstract::Transcranial direct current stimulation (tDCS) using intensities ≤ 2 mA on physical and cognitive outcomes has been extensively investigated. Studies comparing the effects of different intensities of tDCS have yielded mixed results and little is known about how higher intensities (> 2 mA) affect outcomes. This study e...
journal_title:Experimental brain research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00221-019-05721-w
更新日期:2020-02-01 00:00:00
abstract::We studied the potential contribution of postsynaptic mechanisms to the depression of reflex excitability which occurs immediately after a voluntary release from tonic muscle contraction. The excitability of the Soleus (Sol) motor pool was tested at rest and after voluntary muscle relaxation. In both cases the Sol H-r...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230904
更新日期:1985-01-01 00:00:00
abstract::The developmental pattern of hippocampal mossy fiber (dentate granule cell axon) innervation to the pyramidal cell layer was examined with anterograde transport methods. Injection of 3H-leucine into the dentate gyrus on PN 1 resulted in labeling of the incipient stratum lucidum extending to, but not beyond, the CA3 re...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248368
更新日期:1988-01-01 00:00:00
abstract::Hemi-seesaw nystagmus (hemi-SSN) is a jerk-waveform nystagmus with conjugate torsional and disjunctive vertical components. Halmagyi et al. in Brain 117(Pt 4):789-803 (1994), reported hemi-SSN in patients with unilateral lesions in the vicinity of the Interstitial Nucleus of Cajal (INC) and suggested that an imbalance...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2376-2
更新日期:2010-09-01 00:00:00
abstract::We ask whether a target's velocity is considered when planning a fast interceptive action. Human volunteers hit targets that could move at different velocities from across a tilted screen (the hand starting 40 cm away from the screen). We examined how the direction in which the hand initially moved depended on the tar...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-1832-2
更新日期:2004-07-01 00:00:00
abstract::We constructed average histograms from responses evoked by flashing stimuli and noted previously described variations in the shape of the response profile, particularly with respect to sharpness of the peak. To express this variable, we measured the half-rise latency, which is the latency from stimulus onset required ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00242177
更新日期:1995-01-01 00:00:00
abstract::Structural changes of the cerebellum have been reported in several psychiatric diseases like schizophrenia, autism and attention-deficit/hyperactivity disorder (ADHD). Beside behavioral deficits children with ADHD often show slight motor abnormalities. Cerebellar malfunction may contribute. The cerebellum is a structu...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-2020-1
更新日期:2010-03-01 00:00:00