Raphespinal and reticulospinal neurons project to the dorsal vagal complex in the rat.

Abstract:

:Stimulation of the caudal raphe nuclei alters visceral functions. The caudal raphe nuclei project to the nucleus of the solitary tract, which receives the central terminations of vagal afferents and plays an important role in the central integration of autonomic activities. The caudal raphe nuclei also project to the somatic and preganglionic autonomic motoneurons of the spinal cord. Diamidino yellow was injected into the nucleus of the solitary tract, and fast blue was injected into either the cervical, thoracic, or lumbar spinal cord. Large numbers of double-labeled neurons were present within the caudal raphe nuclei and the adjacent reticular formation of the medial tegmental field. This observation documents that individual raphespinal and reticulospinal neurons project an axon collateral to the nucleus of the solitary tract. These data demonstrate the anatomic substrate for global modulation of the autonomic motoneuron pool by the caudal raphe nuclei.

journal_name

Exp Brain Res

authors

Manaker S,Fogarty PF

doi

10.1007/BF00241358

subject

Has Abstract

pub_date

1995-01-01 00:00:00

pages

79-92

issue

1

eissn

0014-4819

issn

1432-1106

journal_volume

106

pub_type

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