Abstract：
:The distribution of S1 (first somatosensory area) and S2 (second somatosensory area) neurons projecting to the contralateral S2 was studied with horseradish peroxidase in normal adult cats and in cats aged between 129 and 248 days in which the injected S2 area had been deprived of some of its input by an earlier lesion (on postnatal days 3 to 30; day of birth = day 1) of ipsilateral S1, alone or combined with a lesion of contralateral S2. In animals with S1 lesions, as in the normal controls, labeled neurons were selectively distributed to the regions of the trunk representation and to parts of the forelimb and hindlimb representations; however, the normally acallosal region in the forepaw representation contained scattered labeled neurons in three of the four animals whose S1 had been lesioned during the first postnatal week. In these animals, the distribution of labeled neurons in the contralateral S2 was apparently normal. Furthermore, the additional lesion of this area during the first postnatal week (one animal) did not increase the degree of filling-in of the normally acallosal parts of S1. The partial filling-in of the acallosal parts of S1 is probably due to the preservation to adulthood of some of the callosal neurons which are present in these regions during the early postnatal life. Possibly, these neurons did not disappear (or lose their callosal axons) because the neonatal lesion (i) allowed their successful competition for terminal space in contralateral S2 or (ii) induced a reorganization of the peripheral input to this area.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Caminiti R,Innocenti GMdoi
10.1007/BF00235729subject
Has Abstractpub_date
1981-01-01 00:00:00pages
53-62issue
1eissn
0014-4819issn
1432-1106journal_volume
42pub_type
杂志文章abstract：:We used the framework of the uncontrolled manifold (UCM) hypothesis to analyze the structure of finger force variability in discrete (ramp) and oscillatory force production tasks performed by the index and middle fingers of the right hand acting in parallel. Subjects performed the tasks at fast and slow rates, with an...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1196-4
更新日期：2002-10-01 00:00:00
abstract：:The responses of 80 amygdaloid neurons to the four basic taste (sucrose, NaCl, HCl and quinine hydrochloride), thermal (5 degrees C, 20 degrees C and 40 degrees C) and tactile (brushing) stimuli applied to the anterior part of the tongue were recorded in anesthetized rats. About 90% of the taste-sensitive amygdaloid n...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237437
更新日期：1984-01-01 00:00:00
abstract：:The primary objective of this study was to explore why preischemic hypoglycemia, which restricts tissue acidosis during the ischemic insult, does not ameliorate cell damage incurred as a result of transient ischemia. The question arose whether hypoglycemia (plasma glucose concentration 2-3 mM) delays resumption of ext...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00233036
更新日期：1995-01-01 00:00:00
abstract：:Studies of the effects of physical activity on cognition suggest that aerobic fitness can improve cognitive abilities. However, the physiological mechanisms for the cognitive benefit of aerobic fitness are less well understood. We examined the association between aerobic fitness and cerebrovascular function with neuro...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5230-6
更新日期：2018-05-01 00:00:00
abstract：:Movements of the dominant and nondominant hand have been claimed to differ with respect to how they take intersegmental dynamics into account. Consistent with this claim, movements of the dominant hand are hypothesized to better exploit the intrinsic limb dynamics, whereas movements of the nondominant hand are control...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0747-5
更新日期：2007-04-01 00:00:00
abstract：:Human sensorimotor synchronization is flexible but subject to temporal constraints. Previous research has shown that musicians tend to lose synchrony with target tones in an isochronous sequence when the sequence rate exceeds 8-10 Hz, presumably because phase correction ceases to function. The present study investigat...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2462-5
更新日期：2011-01-01 00:00:00
abstract：:Tactile motion perception is one of the most important functions for realizing a delicate appreciation of the tactile world. To explore the neural dynamics of motion processing in the brain, the motion adaptation phenomenon can be a useful probe. Tactile motion aftereffects (MAE), however, have not been reported in a ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0979-z
更新日期：2007-07-01 00:00:00
abstract：:People are good at telling the direction of a moving tactile stimulus and this capacity provides a sensitive clinical test of somatosensory disturbances. Tactile directional sensitivity depends on two different kinds of somatosensory information, i.e. spatiotemporal information and information about friction-induced c...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-2343-5
更新日期：2005-10-01 00:00:00
abstract：:Efferents originating from the rat medial prefrontal cortex and projecting to diencephalic and mesencephalic structures were analyzed electrophysiologically. The antidromic activation technique was used in order to identify cortical neurons which innervate the medio-dorsal nucleus of the thalamus (MD), lateral habenul...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239191
更新日期：1983-01-01 00:00:00
abstract：:Previous data have indicated that, if guinea pigs are deprived of all visual information during a crucial period early in development (26-30 days after birth), the map of auditory space in the superior colliculus (SC) is completely disrupted. In the experiments reported here, multi-unit auditory receptive fields were ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00241121
更新日期：1995-01-01 00:00:00
abstract：:Many previous studies have demonstrated the existence of neurons with tremor-frequency activity ("tremor cells") in the thalamus of Parkinson's disease (PD) patients and these neurons are presumed to play a role in the pathogenesis of tremor. Since a major input to motor thalamus (Voa and Vop) is from the internal seg...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005606
更新日期：1997-03-01 00:00:00
abstract：:The activity of 28 cells located mainly in the secondary auditory cortex (A II) of awake squirrel-monkeys, was extracellularly recorded for periods of up to 6 h. Seven different species-specific vocalizations, which were repeatedly presented to the monkey, were used as auditory stimuli. Twenty-six cells responded, at ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239144
更新日期：1979-02-15 00:00:00
abstract：:Long-range tactile masking has been reported between mirror symmetric body locations. This suggests a general principle of contralateral inhibition between corresponding points on each side of the body that may serve to enhance distinguishing touches on the two halves of the body. Do such effects occur before or after...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4485-4
更新日期：2016-02-01 00:00:00
abstract：:The microtubule associated tau protein becomes hyperphosphorylated in Alzheimer's disease (AD). While hyperphosphorylation promotes neurodegeneration, the cause and consequences of this abnormal modification are poorly understood. As impaired energy metabolism is an important hallmark of AD progression, we tested whet...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-018-5341-0
更新日期：2018-11-01 00:00:00
abstract：:A photograph of an action contains implicit information about the depicted motion. Previous studies using either psychophysics or neuroimaging suggested that the neural processing of implied-motion images shares some features of real-motion processing. According to the hypothesis that the target depicted in photograph...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2598-y
更新日期：2011-04-01 00:00:00
abstract：:Our aim was to describe the differences in the presence of trigger points (TrPs) in the shoulder muscles and to investigate the presence of mechanical hypersensitivity in patients with unilateral shoulder impingement and healthy controls. Twelve patients with strictly unilateral shoulder impingement and 10 matched con...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2196-4
更新日期：2010-05-01 00:00:00
abstract：:The goal of this study was to identify the control mechanism used for locomotion pointing regulation under different external temporal constraints. Subjects ( n=8) had to walk on a treadmill through a number of virtual hallways and cross a pair of gliding doors that opened and closed at a constant preset frequency (0....
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0990-8
更新日期：2002-03-01 00:00:00
abstract：:The purposes of this pilot study were to create a model of focal cortical ischemia in Macaca fascicularis and to explore contributions of the reticulospinal system in recovery of reaching. Endothelin-1 was used to create a focal lesion in the shoulder/elbow representation of left primary motor cortex (M1) of two adult...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4390-x
更新日期：2015-11-01 00:00:00
abstract：:This study addressed some of the controversial issues surrounding the anticonvulsant effect of phenytoin, and the predictive validity of the guinea-pig kindling model for the screening of anticonvulsant drugs. Following an intraperitoneal injection of either 50 or 75 mg/kg phenytoin, we analysed plasma concentrations ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210100852
更新日期：2001-10-01 00:00:00
abstract：:In healthy subjects, suprathreshold repetitive transcranial magnetic stimulation (rTMS) at frequencies >2 Hz prolongs the cortical silent period (CSP) over the course of the train. This progressive lengthening probably reflects temporal summation of the inhibitory interneurons in the stimulated primary motor cortex (M...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0296-3
更新日期：2006-06-01 00:00:00
abstract：:The present experiment investigated the effects of aging on emotional behavior, without concomitant influences from any previous behavioral manipulation apart from weighing the rats. Anxiety-related behaviors were measured in the elevated plus-maze (EPM). Performance in the open field (OF) was also assessed to control...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-2240-y
更新日期：2005-07-01 00:00:00
abstract：:Transcranial direct current stimulation (tDCS) induces cortical excitability changes in animals and humans that can last beyond the duration of stimulation. Preliminary evidence suggests that tDCS may have an analgesic effect; however, the timing of these effects, especially when associated with consecutive sessions o...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3149-x
更新日期：2012-08-01 00:00:00
abstract：:Ocular responses to optokinetic stimulation were reexamined in adult albino rats of two different strains. Eye movements were measured in head-restrained animals using the search coil method. In contrast to some previous results, the albino rats showed optokinetic nystagmus, and some of them made responses comparable ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235639
更新日期：1985-01-01 00:00:00
abstract：:The mechanisms of the clasp-knife reflex were studied in the soleus muscle of an animal model, the decerebrate cat with a dorsal hemisection of the lower thoracic cord. The reflex is shown to be autogenetic, and to depend on muscle length in keeping with previous suggestions. However, the magnitude of the inhibition i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF01474257
更新日期：1979-09-01 00:00:00
abstract：:Fast goal-directed voluntary movements of the human upper extremity are known to be associated with three distinct bursts of EMG activity in antagonistic muscles. The role of each burst (AG1, ANT, AG2) in controlling motion is not fully understood, largely because overall limb response is a complex function of the ent...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236850
更新日期：1986-01-01 00:00:00
abstract：:Intracortical inhibition was investigated in normal human volunteers by paired-pulse transcranial magnetic stimulation, using a new, computer-assisted threshold-tracking method. Motor threshold was defined as the stimulus amplitude required to evoke a motor evoked potential of 0.2 mV (peak-to-peak) in abductor pollici...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0988-2
更新日期：2002-03-01 00:00:00
abstract：:"Quiet standing" is standing without intended movement. To the naked eye, a person "quiet standing" on a rigid surface of support is stationary. In the laboratory quiet standing is indexed by behavior (at the millimeter scale) of the center of pressure (COP), the point location of the vertical ground reaction force ve...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3696-9
更新日期：2013-12-01 00:00:00
abstract：:The proportions and some of the properties of X and Y cells in lateral geniculate nucleus (LGN) of adult cats were measured 14-16 days after monocular paralysis. The paralysis was produced by sectioning cranial nerves III, IV and VI. No difference from normal was observed in the proportions of X and Y cells either in ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236898
更新日期：1981-01-01 00:00:00
abstract：:Saccular and utricular organs are essential for postural stability and gaze control. Although saccular and utricular inputs are known to terminate on vestibular neurons, few previous studies have precisely elucidated the origin of these inputs. We investigated the saccular and utricular inputs to single vestibular neu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002219900312
更新日期：2000-04-01 00:00:00
abstract：:Does the brain use a separate internal model for cursor mechanics during visuomotor adaptation? We compared the amount of adaptation and transfer to the opposite arm when subjects reached the targets under different viewing conditions of the arm during reaching. If the brain forms separate models, we predict a differe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2155-0
更新日期：2010-05-01 00:00:00
