Mechanisms of the clasp-knife reflex studied in an animal model.

Abstract:

:The mechanisms of the clasp-knife reflex were studied in the soleus muscle of an animal model, the decerebrate cat with a dorsal hemisection of the lower thoracic cord. The reflex is shown to be autogenetic, and to depend on muscle length in keeping with previous suggestions. However, the magnitude of the inhibition increases with increasing initial force, and the inhibition is mimicked by gentle manipulation of the muscle and tendon surface. Concurrent muscle afferent recordings showed that the electromyogram (emg) reduction was not a result of a decline in Ia afferent input and was not well related to secondary or tendon organ afferent discharge. It is now known that many group III and some group IV muscle afferents are also activated by muscle stretch and contraction, and we here report limited stretch sensitivity in four non-spindle group II afferents. Since these fiber groups each include afferents that produce inhibition of extensor motoneurons, it is proposed that the clasp-knife reflex may result from the activation of these slowly conducting afferent fibers.

journal_name

Exp Brain Res

authors

Rymer WZ,Houk JC,Crago PE

doi

10.1007/BF01474257

subject

Has Abstract

pub_date

1979-09-01 00:00:00

pages

93-113

issue

1

eissn

0014-4819

issn

1432-1106

journal_volume

37

pub_type

杂志文章
  • Androgen target cells in spinal cord, spinal ganglia, and glycogen body of chick embryos. Autoradiographic localization.

    abstract::After injection of 3H dihydrotestosterone, concentration and retention of radioactivity occur in nuclei of certain neurons in the spinal cord and spinal ganglia as well as in dorsal and ventral root cells of chick embryos at day 10, 12, and 18. Cell of the glycogen body show nuclear labeling at day 12, but not at day ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00236561

    authors: Reid FA,Gasc JM,Stumpf WE,Sar M

    更新日期:1981-01-01 00:00:00

  • Corticobulbar and corticospinal projections to neck muscle motoneurons in man. A functional study with magnetic and electric transcranial brain stimulation.

    abstract::The cortical projections to neck muscle motoneurons were studied in normal subjects by electrical and magnetic transcranial brain stimulation. After magnetic stimulation with a large coil, motor evoked potentials were present in about 20% of relaxed and 100% of contracting neck muscles. The latency of these responses ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00231857

    authors: Berardelli A,Priori A,Inghilleri M,Cruccu G,Mercuri B,Manfredi M

    更新日期:1991-01-01 00:00:00

  • Reciprocal changes in expression of mRNA for nerve growth factor and its receptors TrkA and LNGFR in brain of aged rats in relation to maze learning deficits.

    abstract::Quantitative in situ hybridization was used to examine the expression of mRNA for nerve growth factor (NGF) and its receptors, p140Trk (TrkA) and p75LNGFR (LNGFR), in different brain regions of adult (3-month-old) and aged (27-month-old) Wistar rats. The brain regions studied were hippocampus (dentate gyrus, CA3 regio...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/pl00005629

    authors: Hasenöhrl RU,Söderstróm S,Mohammed AH,Ebendal T,Huston JP

    更新日期:1997-04-01 00:00:00

  • Hitting moving targets: a dissociation between the use of the target's speed and direction of motion.

    abstract::Previous work has indicated that people do not use their judgment of a target's speed to determine where to hit it. Instead, they use their judgment of the target's changing position and an expected speed (based on the speed of previous targets). In the present study we investigate whether people also ignore the targe...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-003-1556-8

    authors: Brouwer AM,Middelburg T,Smeets JB,Brenner E

    更新日期:2003-10-01 00:00:00

  • Movement sway: changes in postural sway during voluntary shifts of the center of pressure.

    abstract::We introduce a method for quantification of movement sway--spontaneous migrations of the center of pressure (COP) during its voluntary shifts. Subjects stood on a force platform or on a board with a narrow support surface ("unstable board") and performed voluntary cyclic shifts of the COP at different frequencies. Mov...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-003-1419-3

    authors: Latash ML,Ferreira SS,Wieczorek SA,Duarte M

    更新日期:2003-06-01 00:00:00

  • Adaptation of arm trajectory during continuous drawing movements in different dynamic environments.

    abstract::Human subjects can readily adapt their movement trajectories to different dynamic or visuomotor environments. The focus of the current study was to determine whether subjects could simultaneously adapt to multiple dynamic environments. Subjects ( n=5) drew ellipses continuously for 70 s using a torquable manipulandum ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-002-1260-0

    authors: Fukushi T,Ashe J

    更新日期:2003-01-01 00:00:00

  • Early manifestation of arm-leg coordination during stepping on a surface in human neonates.

    abstract::The accomplishment of mature locomotor movements relies upon the integrated coordination of the lower and upper limbs and the trunk. Human adults normally swing their arms and a quadrupedal limb coordination persists during bipedal walking despite a strong corticospinal control of the upper extremities that allows to ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-018-5201-y

    authors: La Scaleia V,Ivanenko Y,Fabiano A,Sylos-Labini F,Cappellini G,Picone S,Paolillo P,Di Paolo A,Lacquaniti F

    更新日期:2018-04-01 00:00:00

  • Interactions between temperature regulation and emotional arousal in the rabbit.

    abstract::In our study we examined, in the rabbit, the interactions between temperature regulation and the state of increased vigilance and emotional arousal induced by a Classical Aversive Conditioning Procedure. A Delay Conditioning Procedure was used. The Conditioned Stimulus (CS) was a 1350 Hz, 85 dB tone, the Unconditioned...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00238813

    authors: Franzini C,Lenzi P,Cianci T

    更新日期:1981-01-01 00:00:00

  • Estimating the components of the gap effect.

    abstract::The gap effect refers to the finding that saccadic latencies are typically reduced when a fixation point is removed prior to the appearance of a peripheral target. This reduction in saccadic reaction time (SacRT) is thought to be due to a general warning effect and an oculomotor specific fixation offset that occur whe...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s002219900243

    authors: Pratt J,Bekkering H,Leung M

    更新日期:2000-01-01 00:00:00

  • Not looking while leaping: the linkage of blinking and saccadic gaze shifts.

    abstract::Many vertebrates generate blinks as a component of saccadic gaze shifts. We investigated the nature of this linkage between saccades and blinking in normal humans. Activation of the orbicularis oculi, the lid closing muscle, EMG occurred with 97% of saccadic gaze shifts larger than 33 degrees. The blinks typically beg...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00227203

    authors: Evinger C,Manning KA,Pellegrini JJ,Basso MA,Powers AS,Sibony PA

    更新日期:1994-01-01 00:00:00

  • The role of cocontraction in the impairment of movement accuracy with fatigue.

    abstract::The present experiment was designed to test the hypothesis that fatigue-induced impairment in movement accuracy is caused by a decrease in muscle cocontraction rather than a reduced ability to produce muscular force. Seven participants performed fast and accurate elbow extensions aimed at a target, before and after a ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-007-1264-x

    authors: Missenard O,Mottet D,Perrey S

    更新日期:2008-02-01 00:00:00

  • Attentional shift by gaze is triggered without awareness.

    abstract::Reflexive attentional shift in response to another individual's gaze direction has been reported, but it remains unknown whether this process can occur subliminally. We investigated this issue using facial stimuli consisting of drawings (Experiment 1) and photographs (Experiment 2). The gaze direction was expressed by...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-007-1025-x

    authors: Sato W,Okada T,Toichi M

    更新日期:2007-10-01 00:00:00

  • The effects of preceding moving stimuli on the initial part of smooth pursuit eye movement.

    abstract::We examined whether there are any adaptive effects on the pursuit initiation after a prolonged exposure to moving visual stimuli. The eye movements of six human subjects were recorded with the scleral search-coil technique or a Dual Purkinje Image Eye-tracker system. A random-dot image appeared on a CRT monitor and mo...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-006-0563-y

    authors: Taki M,Miura K,Tabata H,Hisa Y,Kawano K

    更新日期:2006-11-01 00:00:00

  • Effects of neonatal splitting of the optic chiasm on the development of feline visual callosal connections.

    abstract::During normal postnatal development, there is an overproduction and subsequent partial elimination of the callosal projections of cortical areas 17 and 18 in the cat. In the present study, we investigated how neonatal splitting of the optic chiasm affects this process. Our results indicate that neonatal splitting of t...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00242013

    authors: Boire D,Morris R,Ptito M,Lepore F,Frost DO

    更新日期:1995-01-01 00:00:00

  • Avian locomotion activated by brainstem infusion of neurotransmitter agonists and antagonists. II. gamma-Aminobutyric acid.

    abstract::The companion article (Sholomenko et al. 1991) described the brainstem locomoter regions in the bird where direct intracerebral injection of a number of putative excitatory neurochemicals, including cholinergic agonists, N-methyl-d-aspartate (NMDA) and Substance P, evoke locomotion. Using the same experimental protoco...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00231753

    authors: Sholomenko GN,Funk GD,Steeves JD

    更新日期:1991-01-01 00:00:00

  • Effect of accuracy constraint on joint coordination during pointing movements.

    abstract::Given the number of muscles and joints of the arm, more ways are available to produce an identical hand movement when pointing to a target than are strictly necessary. How the nervous system manages these abundant degrees of freedom was the focus of this study of pointing to targets of low and high indices of difficul...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-002-1357-5

    authors: Tseng YW,Scholz JP,Schöner G,Hotchkiss L

    更新日期:2003-04-01 00:00:00

  • Unilateral up-regulation of glutamate receptors in limbic regions of amygdaloid-kindled rats.

    abstract::Quantitative autoradiography was used to examine central binding sites for L-[3H]glutamate in amygdaloid-kindled rats since receptors for excitatory amino acids have been implicated in epileptiform activity and seizure behaviors. In tissue from rats killed five days after two kindled seizures, the ipsilateral hippocam...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00231751

    authors: Cincotta M,Young NA,Beart PM

    更新日期:1991-01-01 00:00:00

  • Emotional effects on time-to-contact judgments: arousal, threat, and fear of spiders modulate the effect of pictorial content.

    abstract::Recently, responses to looming visual stimuli have been shown to depend on the emotional content of the stimulus. A threatening stimulus is judged to arrive sooner compared to a neutral stimulus, possibly buying the organism time to prepare defensive actions. Here, we explored the underlying mechanism. We found that t...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-014-3930-0

    authors: Brendel E,Hecht H,DeLucia PR,Gamer M

    更新日期:2014-07-01 00:00:00

  • Gravity prior in human behaviour: a perceptual or semantic phenomenon?

    abstract::Humans show a gravitational advantage in perception: we are more precise at judging the speed of downwards-moving than upwards-moving objects, indicating that gravitational acceleration is an internalised prior. However, it is unclear whether this gravity prior is based on purely perceptual cues or whether it can inco...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-020-05852-5

    authors: Gallagher M,Torok A,Klaas J,Ferrè ER

    更新日期:2020-09-01 00:00:00

  • Antinociceptive effects induced by intra-lateral habenula complex injection of the galanin receptor 1 agonist M617 in rats.

    abstract::The present study was performed to explore the antinociceptive effects of the galanin receptor 1 agonist M617 in lateral habenula complex in rats. Intra-lateral habenula injection of 0.1, 0.5, 1 or 2 nmol of galanin induced dose-dependent increases in hindpaw withdrawal latencies (HWLs) to noxious thermal and mechanic...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-015-4480-9

    authors: Fu LB,Wang Y,Sun XX,Liu XX,Wang Y,Zhuang W

    更新日期:2016-02-01 00:00:00

  • The retino-geniculo-cortical pathway in Callithrix. I. Intraspecific variations in the lamination pattern of the lateral geniculate nucleus.

    abstract::Injections of tritiated tracer precursors into one eye revealed a highly variable lamination pattern of the LGN in the marmoset Callithrix. In one specimen, only four cell layers were apparent with some indication of further differentiation. In a second specimen, six almost complete relay layers were found in the occi...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00235574

    authors: Spatz WB

    更新日期:1978-11-15 00:00:00

  • Relationship between motor activity-related cortical potential and voluntary muscle activation.

    abstract::The purpose of this study was to investigate the relationship between EEG-derived motor activity-related cortical potential (MRCP) and voluntary muscle activation. Eight healthy volunteers participated in two experimental sessions. In one session, subjects performed isometric elbow-flexion contractions at four intensi...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s002210000382

    authors: Siemionow V,Yue GH,Ranganathan VK,Liu JZ,Sahgal V

    更新日期:2000-08-01 00:00:00

  • The amplitude and phase precision of 40 Hz auditory steady-state response depend on the level of arousal.

    abstract::The aim of this study was to investigate, in healthy subjects, the modulation of amplitude and phase precision of the auditory steady-state response (ASSR) to 40 Hz stimulation in two resting conditions varying in the level of arousal. Previously, ASSR measures have shown to be affected by the level of arousal, but th...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-007-1111-0

    authors: Griskova I,Morup M,Parnas J,Ruksenas O,Arnfred SM

    更新日期:2007-10-01 00:00:00

  • Impaired visuomotor adaptation in adults with ADHD.

    abstract::Attention-deficit hyperactivity disorder (ADHD) is a prevalent psychiatric disorder in children that often continues into adulthood. It has been suggested that motor impairments in ADHD are associated with underlying cerebellar pathology. If such is the case, individuals with ADHD should be impaired on motor tasks req...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-014-4190-8

    authors: Kurdziel LB,Dempsey K,Zahara M,Valera E,Spencer RM

    更新日期:2015-04-01 00:00:00

  • Imagined and actual arm movements have similar durations when performed under different conditions of direction and mass.

    abstract::Several experiments have suggested that similar physiological substrates are involved in movement execution and motor imagery, and that the same laws of movement control apply to both processes. Using a mental chronometry paradigm, we examined the effects of movement direction and added mass on the duration of actual ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-002-1012-1

    authors: Papaxanthis C,Schieppati M,Gentili R,Pozzo T

    更新日期:2002-04-01 00:00:00

  • Muscimol inactivation caudal to the interstitial nucleus of Cajal induces hemi-seesaw nystagmus.

    abstract::Hemi-seesaw nystagmus (hemi-SSN) is a jerk-waveform nystagmus with conjugate torsional and disjunctive vertical components. Halmagyi et al. in Brain 117(Pt 4):789-803 (1994), reported hemi-SSN in patients with unilateral lesions in the vicinity of the Interstitial Nucleus of Cajal (INC) and suggested that an imbalance...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-010-2376-2

    authors: Das VE,Leigh RJ,Swann M,Thurtell MJ

    更新日期:2010-09-01 00:00:00

  • Binocular fixation in the rhesus monkey: spatial and temporal characteristics.

    abstract::The horizontal and vertical components of the positions of both eyes of rhesus monkeys were measured during periods of binocularly stable eye positions (eye pauses) while the animals fixated a small target. Differences between monocular and binocular viewing, as well as effects of target size and background illuminati...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00236231

    authors: Motter BC,Poggio GF

    更新日期:1984-01-01 00:00:00

  • Spatial frequency tuning and contrast threshold of striate neurons in Siamese cats.

    abstract::The spatial frequency tuning and the contrast-response function of striate neurons in Siamese cats were investigated with drifting sinusoidal gratings of high contrast, and the results were compared to the data obtained in normally pigmented cats. The optimal spatial frequency of the tuning curves obtained from Siames...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00236278

    authors: Chino YM,Shansky MS,Jankowski WL

    更新日期:1984-01-01 00:00:00

  • Human eye-head coordination in two dimensions under different sensorimotor conditions.

    abstract::The coordination between eye and head movements during a rapid orienting gaze shift has been investigated mainly when subjects made horizontal movements towards visual targets with the eyes starting at the centre of the orbit. Under these conditions, it is difficult to identify the signals driving the two motor system...

    journal_title:Experimental brain research

    pub_type: 临床试验,杂志文章

    doi:10.1007/pl00005663

    authors: Goossens HH,Van Opstal AJ

    更新日期:1997-05-01 00:00:00

  • Temporal factors in target selection with saccadic eye movements.

    abstract::Decision times involved in selecting visual targets with saccadic eye movements in rhesus monkeys were studied for three tasks in which single targets, paired targets with varied asynchronies, and multiple targets requiring a discrimination were presented. Probability of target choice in the paired-target task was str...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-003-1653-8

    authors: Schiller PH,Kendall J

    更新日期:2004-01-01 00:00:00