Abstract：
:The companion article (Sholomenko et al. 1991) described the brainstem locomoter regions in the bird where direct intracerebral injection of a number of putative excitatory neurochemicals, including cholinergic agonists, N-methyl-d-aspartate (NMDA) and Substance P, evoke locomotion. Using the same experimental protocol, this study focuses on the locomotor effects following discrete brainstem injections of the inhibitory neurotransmitter, gamma-aminobutyric acid (GABA), and some of GABA agonists and antagonists. Brainstem regions that were electrically and chemically stimulated included the ventromedial medullary reticular formation, the pontobulbar locomotor strip of the dorsolateral pons and medulla, the pontine reticular formation, and the mesencephalic reticular formation. Locomotion was evoked after the injection of the GABA antagonists picrotoxin (a GABAA receptor antagonist) and bicuculline (GABAA antagonist) into several brainstem locomoter regions. Brainstem stimulated locomotion (both chemically and electrically induced) could be transiently blocked by intracerebral infusion of GABA and irreversibly blocked by muscimol (GABAA agonist). Our avian results are similar to those described for mammals and provide support for the suggestion that motor circuitry, at least at brainstem levels, is similar in all vertebrates.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Sholomenko GN,Funk GD,Steeves JDdoi
10.1007/BF00231753keywords:
subject
Has Abstractpub_date
1991-01-01 00:00:00pages
674-81issue
3eissn
0014-4819issn
1432-1106journal_volume
85pub_type
杂志文章abstract：:Activation of glial cells has been proposed to contribute to neuronal dysfunction and neuronal cell death in Alzheimer's disease. In this study, we attempt to determine some of the effects of secreted factors from activated murine N-11 microglia on viability and morphology of neurons using the differentiated neuroblas...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1389-5
更新日期：2003-05-01 00:00:00
abstract：:Perceived motion may be a stimulus for anticipatory slow eye movements. To test this possibility, the production of anticipatory slow eye movements in humans was studied using apparent motion stimuli. Short range apparent motion was produced with random dot stimuli and the anticipatory slow eye movements were isolated...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247357
更新日期：1989-01-01 00:00:00
abstract：:Patients with Parkinson's disease (PD) commonly exhibit difficulties performing simultaneous tasks and levodopa has been shown to improve the performance of these movements to a greater extent than movements performed in isolation. The aim of this study was to compare the effects of acute unilateral pallidal lesions (...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-002-1257-8
更新日期：2002-12-01 00:00:00
abstract：:Fast goal-directed voluntary movements of the human upper extremity are known to be associated with three distinct bursts of EMG activity in antagonistic muscles. The role of each burst (AG1, ANT, AG2) in controlling motion is not fully understood, largely because overall limb response is a complex function of the ent...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236850
更新日期：1986-01-01 00:00:00
abstract：:Abstract. Although the contribution of binocular vision to reach-to-grasp movements has been extensively studied, it has been largely ignored in locomotion. The aim of these studies was to explore the role of binocular vision during the approach phase and step over the obstacle and the contribution of head movements t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0948-x
更新日期：2002-02-01 00:00:00
abstract：:Single unit activity was recorded from tuberoinfundibular neurones in urethane-anaesthetized pro-oestrous rats. Responses following single shock (0.2 Hz) stimulation of the preoptic area/anterior hypothalamus (PO/AH) or nucleus accumbens (ACB) were recorded and computed for 137 single units. More cells were shown, by ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236546
更新日期：1985-01-01 00:00:00
abstract：:Neuronal activity was studied in the primary (M1), supplementary (M2), dorsal premotor (PMd), and ventral premotor (PMv) cortex of awake, behaving rhesus monkeys. The animals performed forelimb movements to three targets, each approached by three different types of trajectories. With one trajectory type, the monkey mo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231153
更新日期：1991-01-01 00:00:00
abstract：:The blood-brain barrier (BBB) arises from epithelial-like tight junctions that virtually cement adjoining capillary endothelium together in the brain microvasculature. Several experimental manipulations have been shown able to increase the permeability of brain capillaries, by altering endothelial cell membrane integr...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005725
更新日期：1997-07-01 00:00:00
abstract：:Previous studies have shown that the "synaptic" bodies of mammalian pinealocytes are a heterogeneous group of organelles. Whereas "synaptic" ribbons (SR) exhibit a day/night rhythm with small numbers during daytime and high numbers at night, the so-called "synaptic" spherules (SS) show species-specific differences in ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236214
更新日期：1987-01-01 00:00:00
abstract：:The evidence on the impact of subthalamic nucleus deep brain stimulation (STN-DBS) on action restraint on Go/NoGO reaction time (RT) tasks in Parkinson's disease (PD) is inconsistent; with some studies reporting no effect and others finding that STN stimulation interferes with withholding of responses and results in m...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4531-2
更新日期：2016-04-01 00:00:00
abstract：:The European Resuscitation Guidelines recommend that survivors of cardiac arrest (CA) be resuscitated with 100% O2 and undergo subsequent-post-return of spontaneous circulation (ROSC)-reduction of O2 supply to prevent hyperoxia. Hyperoxia produces a "second neurotoxic hit," which, together with the initial ischemic in...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-020-05746-6
更新日期：2020-04-01 00:00:00
abstract：:Sequential intraocular grafting of defined areas from fetal rat brain to adult host rats was used to explore the possibility that such double grafts would become interconnected. Norepinephrine- containing neurons of the locus coeruleus were grafted together with either parietal cerebral cortex, hippocampus, or the cau...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236784
更新日期：1979-03-09 00:00:00
abstract：:Albinism affects the anatomy and physiology of the visual system in mammals. Behavioural, anatomical and in vivo electrophysiological investigations revealed that the optokinetic reflex is abnormal and retinal slip neurons in the nucleus of the optic tract and the dorsal terminal nucleus of the accessory optic system ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1722-8
更新日期：2009-12-01 00:00:00
abstract：:The stronger anatomo-functional connections of the supplementary motor area (SMA), as compared with premotor area (PM), with regions of the limbic system, suggest that SMA could play a role in the control of movements triggered by visual stimuli with emotional content. We addressed this issue by analysing the modifica...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1346-8
更新日期：2003-03-01 00:00:00
abstract：:Emotional processing that occurs partially in advance of perceptual processing is known as pre-perceptual emotional processing. The facilitation of sensory processing due to pre-perceptual emotional processing can be observed in visual search and attentional blink tasks. However, previous event-related potential studi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4486-3
更新日期：2016-02-01 00:00:00
abstract：:Electrical stimulation with repetitive pulses (6/sec) was applied to the internal medullary lamina and produced tonic contraversive turning movements of eyes and head which were associated with recruiting responses in the visual cortex. Optical gratings of a spatial frequency of 0.5 c/deg which alternated with diffuse...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00234015
更新日期：1976-06-18 00:00:00
abstract：:The purpose of this study was to determine whether the neuromuscular control of goal-directed movements is different for young and older adults with the upper and lower limbs. Twenty young (25.1 ± 3.9 years) and twenty older adults (71.5 ± 4.8 years) attempted to accurately match the displacement of their limb to a sp...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3868-2
更新日期：2014-06-01 00:00:00
abstract：:Adequate postural control is a prerequisite for daily activities such as reaching for an object. However, knowledge on the relationship between postural adjustments and the quality of reaching movements during human ontogeny is scarce. Therefore we evaluated the development of the relationship between the kinematic fe...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0964-6
更新日期：2007-08-01 00:00:00
abstract：:Interval timing deficiencies in Parkinson's disease (PD) patients have been a matter of debate. Here we test the possibility of PD heterogeneity as a source for this discrepancy. Temporal performance of PD patients and control subjects was assessed during two interval tapping tasks and during a categorization task of ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1097-7
更新日期：2008-01-01 00:00:00
abstract：:A photographic technique was used to study the evolution of lateral head-tilt following hemilabyrinthectomy in adult cats. Animals were maintained post-operatively in normally lit conditions (LM cats), in total darkness (DM cats), or in stroboscopic light. In LM casts, the head tilt peaked at 45 degrees (with the lesi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235707
更新日期：1977-06-27 00:00:00
abstract：:After minimizing proprioceptive input from the legs by ischemia without degradation of muscle force and excluding visual stabilization by eye closure, a characteristic anterior-posterior postural sway around 1 Hz was observed in three normal subjects. This is similar to the instability seen in two tabes dorsalis patie...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237939
更新日期：1980-01-01 00:00:00
abstract：:It was previously proposed that a linkage between the optokinetic system and the stereoscopic system in higher mammals serves to allow these animals to selectively stabilize those parts of the visual scene which lie in the plane of convergence as the animals move forward in a three-dimensional world (Howard and Ohmi, ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228902
更新日期：1989-01-01 00:00:00
abstract：:We investigated how lateralized choices of hand and target are influenced by previous behavior. Three monkeys retrieved food pellets following cues indicating the location of available food pellet targets, and the hand that could be used to acquire a target. In pseudo-randomized trials, the monkeys could retrieve food...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0481-z
更新日期：2006-10-01 00:00:00
abstract：:When a target moves to a new location during a rapid aiming movement, the hand follows it, even when the participant intends not to. Pisella et al. (Nat Neurosci 3:729-736, 2000) claim that the posterior parietal cortex, in the dorsal visual stream, is responsible for this 'automatic pilot'. Here we study the limits o...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0935-y
更新日期：2007-08-01 00:00:00
abstract：:In the base of each temporal lobe in 4 monkeys (Macaca fascicularis) we sectioned the pia mater in an antero-posterior line along the most medial part of the inferior temporal visual association cortex (area TE), lateral to the parahippocampal cortex. This pial section interrupts the blood flow in branches of the post...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228525
更新日期：1991-01-01 00:00:00
abstract：:Previous studies have shown that rearing rabbits in a stroboscopically illuminated environment results in a decrease in orientation and direction selectivity and an increase in responsivity to stroboscopic stimuli among neurons in area 17. In the present study, the critical period for susceptibility to these effects w...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239202
更新日期：1983-01-01 00:00:00
abstract：:The present study was undertaken to investigate the effects of the alpha2 adrenergic agonist, clonidine, on the near complete cerebral ischemia (NCFI) evoked release of glutamate and aspartate from normo- and hyperglycemic rodent brain tissue using microdialysis tissue techniques. Hemodynamic variables, blood lactate,...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0064-4
更新日期：2005-12-01 00:00:00
abstract：:Abnormal automatic postural responses are thought to contribute to balance impairment in Parkinson's disease. However, because postural responses are modifiable by stance, we have speculated that some postural abnormalities in patients with Parkinson's disease are secondary to their stooped stance. We have studied thi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050644
更新日期：1999-02-01 00:00:00
abstract：:Cortical spreading depression (CSD) is influenced by brain excitability and is related to neurological diseases, such as epilepsy. In vitro evidence indicates that neuronal electrical activity is potentiated after CSD. Malnutrition can cause electrophysiological changes in the brain, both in animals and in humans. Her...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2844-3
更新日期：2011-10-01 00:00:00
abstract：:The primary auditory "cortex" field L, of the Guinea fowl is a three layer tonotopically organized structure. Isofrequency planes as shown with the 2-deoxyglucose (2DG) method cut across these layers and with their second dimension extend in rostro-caudal direction. The input layer L2 exhibits "spontaneous" labeling d...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238839
更新日期：1981-01-01 00:00:00
