Abstract：
:Neuronal activity was studied in the primary (M1), supplementary (M2), dorsal premotor (PMd), and ventral premotor (PMv) cortex of awake, behaving rhesus monkeys. The animals performed forelimb movements to three targets, each approached by three different types of trajectories. With one trajectory type, the monkey moved its hand straight to the target, with another, the path curved in a clockwise direction, and with a third, the path curved in a counter-clockwise direction. We examined whether neuronal activity in these areas exclusively reflects a hand movement's net distance and direction or, alternatively, whether other factors also influence cortical activity. It was found that neuronal activity during all phases of a trial reflects aspects of movement in addition to target location. Among these aspects may be selection of an integrated motor act from memory, perhaps specifying the entirety of a path by which the hand moves to a target.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Hocherman S,Wise SPdoi
10.1007/BF00231153subject
Has Abstractpub_date
1991-01-01 00:00:00pages
285-302issue
2eissn
0014-4819issn
1432-1106journal_volume
83pub_type
杂志文章abstract：:The cortical projections to neck muscle motoneurons were studied in normal subjects by electrical and magnetic transcranial brain stimulation. After magnetic stimulation with a large coil, motor evoked potentials were present in about 20% of relaxed and 100% of contracting neck muscles. The latency of these responses ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231857
更新日期：1991-01-01 00:00:00
abstract：:It is known that, when both forearms are rotated rhythmically and symmetrically, the dominant hand leads in time by about 25 ms, irrespective of movement speed. Positron emission tomography was used to test the hypothesis that the asynchrony results from a functional hemispheric asymmetry. We found that in normal, adu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050428
更新日期：1998-06-01 00:00:00
abstract：:After intracranial transection of the optic nerve in cats the retinal stump of the nerve was injected with HRP. Surviving retinal ganglion cells can be retrogradely labeled at least up to 15.5 months of postoperative survival. ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00261356
更新日期：1985-01-01 00:00:00
abstract：:The moment production by several fingers on a mechanically fixed vertically oriented handle was studied under the systematic variations of task parameters such as (a) moment magnitude (1.0 Nm and 2.0 Nm) and (b) direction of moment production (into pronation and supination), as well as (c) vertical position of the han...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-1859-4
更新日期：2004-08-01 00:00:00
abstract：:Interval timing deficiencies in Parkinson's disease (PD) patients have been a matter of debate. Here we test the possibility of PD heterogeneity as a source for this discrepancy. Temporal performance of PD patients and control subjects was assessed during two interval tapping tasks and during a categorization task of ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1097-7
更新日期：2008-01-01 00:00:00
abstract：:Extracellular recordings were made from neurones in the ventromedial and parafasicular nuclei of the rat thalamus, many of which had demonstrable capsular or caudate projections. These cells responded to electrical stimulation of the ipsilateral substantia nigra with a short latency (4 ms) inhibition presumed to be mo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236662
更新日期：1980-01-01 00:00:00
abstract：:Intracellular recordings from thalamic neurons receiving cerebellar inputs were performed under urethane anesthesia in the rat. A total of 64 neurons were recorded intracellularly with micropipettes filled with 4% biocytin solution (dissolved in 0.5 M K-acetate), and cerebellar-induced EPSPs (CN-EPSPs), the membrane r...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231841
更新日期：1991-01-01 00:00:00
abstract：:Hand muscle reflexes following muscle stretch and electrical nerve stimulation show a typical pattern consisting of short- and long-latency reflexes. The present investigation was designed to test reflexes following pure cutaneous stimulation. Air puffs were delivered to the palmar tip and the nail bed of the first, s...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00242189
更新日期：1995-01-01 00:00:00
abstract：:The organization of corticocortical connections in the representation of the forepaw in cat primary somatosensory cortex (SI) was studied following injections of various tracers into different cortical cytoarchitectonic areas. Small injections of horseradish peroxidase, wheat germ agglutinin-conjugated HRP, Phaseolus ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227839
更新日期：1992-01-01 00:00:00
abstract：:The present experiment was designed to test the hypothesis that fatigue-induced impairment in movement accuracy is caused by a decrease in muscle cocontraction rather than a reduced ability to produce muscular force. Seven participants performed fast and accurate elbow extensions aimed at a target, before and after a ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1264-x
更新日期：2008-02-01 00:00:00
abstract：:Observing an action activates action representations in the motor system. Moreover, the representations of manipulable objects are closely linked to the motor systems at a functional and neuroanatomical level. Here, we investigated whether action observation can facilitate object recognition using an action priming pa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1953-8
更新日期：2010-01-01 00:00:00
abstract：:The effects of learning on strategy selection in the context of action imitation have been investigated in two experiments conducted with healthy individuals. It was predicted that, once learnt, meaningless actions are processed by the cognitive system as meaningful and this new representational status might influence...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-006-0395-9
更新日期：2006-08-01 00:00:00
abstract：:In the metadata of the original publication of the article. ...
journal_title：Experimental brain research
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00221-019-05476-4
更新日期：2019-02-01 00:00:00
abstract：:1. The activity of cat semicircular canal and otolith afferents was studied during yaw and roll rotations, respectively, to examine their dynamic behavior. 2. A sinusoidal analysis of the canal afferent activities showed that their dynamic characteristics are similar to those of second order vestibular neurons, except...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239549
更新日期：1978-08-15 00:00:00
abstract：:The effect of unilateral vestibular deafferentation (UVD) on the linear vestibulo-ocular reflex (LVOR) was studied in 11 humans an average of 52 months following surgical UVD. Controls consisted of seven healthy age-matched subjects. The LVOR was evoked by directionally random, transient whole body interaural (heave) ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2089-5
更新日期：2005-03-01 00:00:00
abstract：:Selective attention is popularly assessed with colour Stroop tasks in which participants name the ink colour of colour words, whilst resisting interference from the natural tendency to read the words. Prior studies hinted that the key brain regions (dorsolateral prefrontal (dlPFC) and anterior cingulate cortex (ACC)) ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-010-2225-3
更新日期：2010-05-01 00:00:00
abstract：:The extent and strength of long-distance coupling between locomotor networks in the rostral and caudal spinal cord of larval lamprey were examined with in vitro brain/spinal cord preparations, in which spinal locomotor activity was initiated by chemical microstimulation in the brain, as well as with computer modeling....
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050719
更新日期：1999-05-01 00:00:00
abstract：:1. The responses are described of cochlear nucleus neurons of anaesthetized cats as a function of time in dependence on intensity and frequency of tonal stimuli. Depending on spectral properties three types are distinguished in the group of spontaneously active units: A type (activation only) AS type (activation and s...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238021
更新日期：1975-10-24 00:00:00
abstract：:To investigate the topographic organization of nociceptive neurons in the caudal medullary reticular formation, the distribution of cells that exhibit c-fos expression was examined following a unilateral noxious facial stimulus: subcutaneous injection of formalin into the vibrissal pad of awake rats. Labelling for Fos...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228014
更新日期：1995-01-01 00:00:00
abstract：:Previously, we observed changes in the scale, rotation, and location of drawn shapes when subjects simultaneously performed a secondary task, but not in the shape or proportion of the drawing. We suggested the secondary task impacted motor planning and execution or proprioception of the primary task. To isolate for pr...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3572-7
更新日期：2013-07-01 00:00:00
abstract：:Rhythmic interlimb coordination is characterized by attraction to stable phase and frequency relations. Sudden, unintended transitions between such coordination patterns have been observed in iso- and multifrequency tasks when movement frequency was gradually increased. These transitions have been accounted for by mod...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002210050257
更新日期：1998-01-01 00:00:00
abstract：:Both vestibular and neck proprioceptive inputs contribute towards maintaining a walking trajectory. We investigated how aging alters neck proprioceptive and vestibular interaction for preserving equilibrium and spatial orientation during locomotion. Young and healthy elderly were exposed to two sensory manipulations a...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-005-0182-z
更新日期：2005-12-01 00:00:00
abstract：:The present study investigated age-related changes in the attentional demands associated with interlimb coordination involving upper and lower limbs performed at three different movement frequencies. Younger and older adults performed rhythmical, 180° out-of-phase flexion-extension movements of the knee and elbow with...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3511-7
更新日期：2013-06-01 00:00:00
abstract：:The effects of electrical stimulation within the midbrain on fusimotor output to the jaw elevator muscles were studied in anaesthetized cats. Muscle spindle afferents recorded in the mesencephalic trigeminal nucleus were categorised as primary or secondary by their responses to succinylcholine during sinusoidal or ram...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227778
更新日期：1993-01-01 00:00:00
abstract：:The effects of alteration of thyroid state on neurochemical maturation have been studied in rats made hypothyroid by daily injections of methimazole or hyperthyroid by daily supplementation with thyroid hormone (T3) from postnatal days 1 to 27. Biochemical assays on seven brain regions plus the spinal cord were carrie...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229834
更新日期：1991-01-01 00:00:00
abstract：:Many neurons in the deeper layers of the superior colliculus (SC) respond to multiple sensory inputs--visual, auditory, and somatic--as well as provide signals essential for saccadic eye movements to targets in different modalities. When the eyes and pinnae are in primary position, the neural map of auditory space is ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231709
更新日期：1995-01-01 00:00:00
abstract：:The study addresses three main questions: (1) Does the magnitude of the grasping force affect the prehension synergies, i.e., conjoint changes of finger forces and moments? (2) Do individual finger forces scale with the total grasping forces ('scale-invariance hypothesis')? (3) How specification of the grasping force ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1675-3
更新日期：2009-03-01 00:00:00
abstract：:The effects of an opioid receptor antagonist, naloxone (NAL), were studied on the changes in pituitary hormone secretion induced by emotional stress. Male Wistar rats were trained with tone stimuli paired with electric footshocks and tested with the tone and environmental cue signals for emotional stress of fear acqui...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230100
更新日期：1990-01-01 00:00:00
abstract：:Migraine affects the autonomous nervous system and a recent investigation has also proposed a severe disturbance of dynamic cerebral blood flow regulation in the middle cerebral artery during spontaneous blood pressure oscillations. This study investigates whether dynamic cerebral autoregulation is impaired in persons...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0879-2
更新日期：2007-07-01 00:00:00
abstract：:The reinforcement learning hypothesis of dopamine function predicts that dopamine acts as a teaching signal by governing synaptic plasticity in the striatum. Induced changes in synaptic strength enable the cortico-striatal network to learn a mapping between situations and actions that lead to a reward. A review of the...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-009-2060-6
更新日期：2010-01-01 00:00:00
