Abstract:
:The present experiment was designed to test the hypothesis that fatigue-induced impairment in movement accuracy is caused by a decrease in muscle cocontraction rather than a reduced ability to produce muscular force. Seven participants performed fast and accurate elbow extensions aimed at a target, before and after a fatigue protocol. The inertia of the manipulandum was decreased after the fatigue protocol so that the ratio of required to available force during movements was identical pre- and post-fatigue. After the fatigue protocol, movement endpoint accuracy decreased and movement endpoint variability increased. These alterations were associated with a decrease in cocontraction. We concluded that the impairment of movement accuracy during fatigue could not be explained by the lack of available force, but was likely to be due to a fatigue-induced decrease in muscular cocontraction. We then speculate that fatigue influences the relative weights of accuracy and energy economy in the optimisation of sensorimotor control.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Missenard O,Mottet D,Perrey Sdoi
10.1007/s00221-007-1264-xsubject
Has Abstractpub_date
2008-02-01 00:00:00pages
151-6issue
1eissn
0014-4819issn
1432-1106journal_volume
185pub_type
杂志文章abstract::Serotonin reveals ineffective (subthreshold) pathways from the C2 lateral funiculus to ipsilateral phrenic motoneurons in spinalized rats. The objective of the present study was to investigate serotonergic modulation of crossed-spinal pathways to contralateral phrenic motoneurons. Rats (n = 10) were anesthetized (uret...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00243214
更新日期:1994-01-01 00:00:00
abstract::Normal subjects standing on an earth-fixed force platform inside a movable room displaced at velocities comparable to those accompanying spontaneous body sway, exhibit a visually evoked postural response (VEPR) some 600 ms after the start of the room movement. It consists of a displacement of the centre of force of th...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237488
更新日期:1986-01-01 00:00:00
abstract::Tactile information is differentially processed over the various phases of goal-directed movements. Here, event-related potentials (ERPs) were used to investigate the neural correlates of tactile and visual information processing during movement. Participants performed goal-directed reaches for an object placed centra...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4589-5
更新日期:2016-05-01 00:00:00
abstract::It is not evident how the small effects of the flankers of the Ebbinghaus figure on peak grip aperture (PGA) should be interpreted. One interpretation is that the flankers influence the estimated size, which in turn influences the grasp. If this interpretation is correct, then only the size-dependent aspects of the gr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2138-0
更新日期:2005-05-01 00:00:00
abstract::The review summarises current evidence on the cognitive mechanisms for the integration of spatial and temporal representations and of common brain structures to process the where and when of stimuli. Psychophysical experiments document the presence of spatially localised distortions of sub-second time intervals and su...
journal_title:Experimental brain research
pub_type: 杂志文章,评审
doi:10.1007/s00221-009-1834-1
更新日期:2009-06-01 00:00:00
abstract::Inhibitory control plays an important role in goal-directed behavior. Although substantial inter-individual variability exists in the behavioral performance of response inhibition, the corresponding modulating neurochemical and neurophysiological mechanisms remain unclear. Thus, the present study aimed to explore the ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-017-5101-6
更新日期:2017-12-01 00:00:00
abstract::We investigated a double-label 2-DG protocol and method of analysis in which sequential injections of 3H- and 14C-2-DG were used to map brain metabolism during two distinct experimental treatments in the same animal. In initial studies, brain sections from rats given only 3H-2-DG or only 14C-2-DG were exposed on Ultro...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00270687
更新日期:1987-01-01 00:00:00
abstract::Neuromagnetic fields from the left cerebral hemisphere of five healthy, right-handed subjects were investigated under three different experimental conditions: (1) electrical stimulation of the right index finger (task S); (2) voluntary movement of the same finger (M); (3) M+S condition, consisting of voluntary movemen...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00230430
更新日期:1996-01-01 00:00:00
abstract::X-ray photography was employed to analyse the postural syndromes following unilateral global and selective lesions of the vestibular apparatus in guinea pigs. Following hemilabyrinthectomy, head rotation in the horizontal plane resulted mainly from rotation of the cervical vertebrae whereas lateral head tilt was due t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00250579
更新日期:1989-01-01 00:00:00
abstract::The purpose of the study was to determine the contributions of endpoint variance and trajectory variability to the endpoint accuracy of goal-directed isometric contractions when the target force and contraction speed were varied. Thirteen young adults (25 +/- 6 years) performed blocks of 15 trials at each of 2 contrac...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-2126-5
更新日期:2010-04-01 00:00:00
abstract::Deep brain stimulation of the subthalamic nucleus (STN DBS) significantly improves clinical motor symptoms, as well as intensive aspects of movement like velocity and amplitude in patients with Parkinson's disease (PD). However, the effects of bilateral STN DBS on integrative and coordinative aspects of motor control ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-018-5197-3
更新日期:2018-04-01 00:00:00
abstract::Unilateral isometric muscle contractions increase motor-evoked potentials (MEPs) produced by transcranial magnetic stimulation not only in the contracting muscle but also in the resting contralateral homologous muscle. Corticospinal excitability in the M1 contralateral to the contracting muscle changes depending on th...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2397-x
更新日期:2010-09-01 00:00:00
abstract::Previous studies reported that the activity of trigeminal motoneurons innervating masseter muscles is modulated by vestibular inputs. We performed the present study to provide an anatomical substrate for these physiological observations. The transynaptic retrograde tracer pseudorabies virus-Bartha was injected into mu...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-0275-8
更新日期:2006-05-01 00:00:00
abstract::According to the size principle for motoneurons one would expect that an excitatory stimulus given to a motoneuronal pool should evoke small excitatory postsynaptic potentials (EPSPs) in large and large EPSPs in small motoneurons of the pool. In this study this expectation was tested for the motoneuron pool of the fir...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229117
更新日期:1994-01-01 00:00:00
abstract::This paper reports on experiments in which the effect of disconnection of association fibres from Area 17/18 to the posterior suprasylvian cortex (PSSC) was investigated. In the control experiments, all neurons had large receptive fields in the central 5-10 degrees of the visual field without detailed retinotopy. In t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235537
更新日期:1983-01-01 00:00:00
abstract::We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered bilaterally at 0.2-2.0 Hz, evokes a potent entrainment of sympathetic outflow to muscle and skin. Most recently, we showed that stimulation at 0.08-0.18 Hz generates two bursts of modulation of muscle sympathetic nerve activity ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3090-z
更新日期:2012-06-01 00:00:00
abstract::In goal-oriented locomotion, healthy adults generate highly stereotyped trajectories and a consistent anticipatory head orienting behaviour, both evidence of top-down, open-loop control. The aim of this study is to describe the typical development of anticipatory orienting strategies and trajectory formation. Our hypo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3495-3
更新日期:2013-05-01 00:00:00
abstract::Previous research has demonstrated that viewing one's hand can induce tactile response compatibility effects at the hands. Here, we investigated the question of whether vision of one's own hand is actually necessary. The Eriksen flanker task was combined with the rubber hand illusion in order to determine whether tact...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-4129-0
更新日期:2015-02-01 00:00:00
abstract::Many activities of daily living involve multi-digit, voluntary rotational manipulations of grasped objects. Yet, only a few studies have focused on coordination of individual fingertip forces during such tasks. The objective of this study was to investigate individual digit contributions to a three-digit task in which...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4289-6
更新日期:2015-07-01 00:00:00
abstract::Voluntary movements are preceded by a slow electrical potential of the brain (Bereitschafts-potential, BP) or readiness potential. The BP is accompanied by a magnetic field shift of similar time characteristics (Bereitschaftsmagnetfeld, BM). The BM preceding volitional right foot or toe movements was recorded from ant...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237152
更新日期:1983-01-01 00:00:00
abstract::Navigation through complex environments requires a greater degree of control and attentional resources from the central nervous system to ensure postural stability and efficient goal completion as compared to quiet standing or unobstructed walking. Furthermore, when a cognitive task is also performed in a dual-task sc...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4461-z
更新日期:2016-02-01 00:00:00
abstract::The major mammalian subcortical visual structures receive topographically ordered projections from both eyes. In the adult dorsal lateral geniculate nucleus (dLGN) each projection terminates in separate restricted regions of the nucleus. This pattern is different during development. Initially in ferrets the projection...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231260
更新日期:1990-01-01 00:00:00
abstract::The actions of alpha-kainic acid (KA) were reexamined in thin sections of the hippocampus and the cerebellum of the guinea pig in view of various discrepancies between our previous findings and reports from other laboratories. Brief pulses of KA ejected in st. lucidum in the CA3 region induced short- and long-lasting ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248508
更新日期:1988-01-01 00:00:00
abstract::The activity of 28 cells located mainly in the secondary auditory cortex (A II) of awake squirrel-monkeys, was extracellularly recorded for periods of up to 6 h. Seven different species-specific vocalizations, which were repeatedly presented to the monkey, were used as auditory stimuli. Twenty-six cells responded, at ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00239144
更新日期:1979-02-15 00:00:00
abstract::The Ca++ -dependence of the repetitive firing of neostriatal neurons was studied in an in vitro slice preparation of the rat neostriatum. Neuronal firing was evoked by injecting depolarizing currents of 100-200 ms duration. In normal conditions, the mode of firing was tonic and showed very little adaptation. The frequ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00248539
更新日期:1989-01-01 00:00:00
abstract::Eye and head movements in the horizontal, frontal and sagittal planes were recorded in the rabbit with a newly developed technique using dual scleral search coils in a rotating magnetic field. The compensatory eye movements elicited by passive sinusoidal oscillation deteriorated for frequencies below 0.1 Hz in the hor...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00236282
更新日期:1984-01-01 00:00:00
abstract::A database of positron-emission-tomography studies published between January 1993 and November 1996 was created to address several questions regarding the function and connectivity of the human anterior cingulate cortex (ACC). Using this database, we have previously reported on the relationship between behavioural var...
journal_title:Experimental brain research
pub_type: 杂志文章,meta分析
doi:10.1007/s002210000400
更新日期:2000-07-01 00:00:00
abstract::We have reported previously that intracranial application of near-infrared light (NIr) reduces clinical signs and offers neuroprotection in a subacute MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) monkey model of Parkinson's disease. In this study, we explored whether NIr reduces the gliosis in this animal model...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4720-7
更新日期:2016-11-01 00:00:00
abstract::In earlier studies the tetrahydroisoquinoline derivative N-methyl-norsalsolinol (2-MDTIQ) was discovered in lumbar cerebrospinal fluid and brain of patients with Parkinson's disease. To establish whether 2-MDTIQ is toxic to the dopaminergic system, 2-MDTIQ or 6-hydroxydopamine (6-OHDA) were stereotactically injected i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227181
更新日期:1996-11-01 00:00:00
abstract::Two experiments were conducted to determine the effects of conditioned circling on the concentrations of dopamine (DA), 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) within discrete regions of the striatum (STR). The first study assessed the inherent regional distributions of these compounds with ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00247949
更新日期:1989-01-01 00:00:00