Abstract：
:The Ca++ -dependence of the repetitive firing of neostriatal neurons was studied in an in vitro slice preparation of the rat neostriatum. Neuronal firing was evoked by injecting depolarizing currents of 100-200 ms duration. In normal conditions, the mode of firing was tonic and showed very little adaptation. The frequency-current relation was linear over a wide range of frequencies. The repetitive firing was first enhanced and later suppressed by Co++, Mn++ and Cd++. These effects on the repetitive firing by the Ca++ -channel blockers paralleled the suppression of the slow afterhyperpolarizing potential. The lowering (0.2 mM) of Ca++ had similar effects. In the presence of TEA (up to 10 mM), the cell fired both Na+ and Ca+ action potentials. The results suggest that, as in other CNS neurons of the vertebrate, in neostriatal neurons the slow afterhyperpolarizing potential (AHP) is due to a Ca++ -activated K+ -conductance, and that the AHP plays a crucial role in the repetitive firing of these neurons.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Galarraga E,Bargas J,Sierra A,Aceves Jdoi
10.1007/BF00248539subject
Has Abstractpub_date
1989-01-01 00:00:00pages
157-68issue
1eissn
0014-4819issn
1432-1106journal_volume
75pub_type
杂志文章abstract：:Static and dynamic otolith, horizontal vestibular and optokinetic ocular reflexes were investigated in pigmented rats 1-6 and more months after unilateral vestibular nerve (UVN) section. Evoked responses were compared with published data from control rats studied under identical conditions. Static lateral tilt of UVN ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050287
更新日期：1998-02-01 00:00:00
abstract：:Most studies of rapid orienting gaze shifts generated by combined eye and head movements have focused on an experimental condition in which gaze displacements are started with the subject's eyes in the normal straight-ahead position in the orbit. Such an experimental approach does not permit a clear identification of ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230204
更新日期：1993-01-01 00:00:00
abstract：:We examined modulation of transmission of short-latency excitation produced by distal hindlimb cutaneous input, as well as fluctuations in motoneuron membrane potential and input resistance, in flexor digitorum longus (FDL) motoneurons during fictive locomotion. Fictive stepping was induced in unaesthetized, decerebra...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00248749
更新日期：1988-01-01 00:00:00
abstract：:The postnatal development of monoamine levels and receptors in the occipital cortex of the cat has been investigated using neurochemical techniques. The endogenous catecholamines (noradrenaline and dopamine) gradually increased with age, displaying an about 12-13-fold increase in their concentration from the newborn t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239212
更新日期：1983-01-01 00:00:00
abstract：:During voluntary movement, muscle spindles of both the agonist and antagonist muscles potentially can supply information about position of the limb. Muscle vibration is known to increase muscle spindle discharge and cause systematic distortions of limb position sense in humans. The following two experiments attempted ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF02423506
更新日期：1990-01-01 00:00:00
abstract：:Despite holding significant promise for counteracting the deleterious effects of ageing on cognitive and motor function, little is known of the effects of facilitatory non-invasive brain stimulation (NBS) techniques on corticospinal excitability (CSE) in older adults. Thirty-three older adults (≥60 years) participated...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4740-3
更新日期：2016-12-01 00:00:00
abstract：:Single neurons in the auditory cortex of anesthetized cats were examined quantitatively for their sensitivity to the sound pressure level of characteristic frequency (CF) tone pulses, and to 6 dB, linear modulations in the amplitude of a continuous CF carrier tone. The direction and rate of amplitude modulation (AM), ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247281
更新日期：1987-01-01 00:00:00
abstract：:We have studied the dynamics of human saccades along various cardinal (horizontal and vertical) and oblique directions in two different experimental paradigms yielding fast and slow saccades, respectively. We found that the saturation of vectorial peak velocity with amplitude, which is already well known from earlier ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228123
更新日期：1990-01-01 00:00:00
abstract：:We investigated the association between the degree of lesion overlap with the corticospinal tract and walking performance before and after 4-weeks of partial body weight support (PBWS) treadmill training in 18 individuals (ten male, eight female) with a mean age 59 +/- 13 years (mean +/- SD), range 32-74 years, who we...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1237-0
更新日期：2008-03-01 00:00:00
abstract：:Under anesthesia with N2O (70%) and halothane (2-4%), complex spikes of Purkinje cells were extracellularly recorded in the nodulus and flocculus of immobilized pigmented rabbits. Optokinetic stimulation (OKS) was delivered to each eye as repetitive movements of a random dot pattern. The visual field of each eye was d...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228792
更新日期：1990-01-01 00:00:00
abstract：:Pyramidal cell structure varies systematically in occipitotemporal visual areas in monkeys. The dendritic trees of pyramidal cells, on average, become larger, more branched and more spinous with progression from the primary visual area (V1) to the second visual area (V2), the fourth (V4, or dorsolateral DL visual area...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0057-3
更新日期：2005-12-01 00:00:00
abstract：:Push-pull cannulae were inserted into both medial and lateral banks of the suprasylvian sulcus and used for local perfusion with artificial extracellular fluid (aECF). Electrical stimulations of regions of cortex projecting to the lateral suprasylvian area (LSA) were accompanied by enhanced levels of release of excita...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00235323
更新日期：1985-01-01 00:00:00
abstract：:The primary objective of this study was to explore why preischemic hypoglycemia, which restricts tissue acidosis during the ischemic insult, does not ameliorate cell damage incurred as a result of transient ischemia. The question arose whether hypoglycemia (plasma glucose concentration 2-3 mM) delays resumption of ext...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00233036
更新日期：1995-01-01 00:00:00
abstract：:This report describes two models of human behavior when detecting displacements of joints that allow one to compare and integrate findings from different proprioception tests in a quantitative way. Results from various tests have led to different and often conflicting conclusions about proprioceptive behaviors and the...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227954
更新日期：1996-12-01 00:00:00
abstract：:In the lateral septal area (LSA), both inhibitory and excitatory dopamine (DA) actions, as well as hypothalamic and midbrain DA efferents, have been described. Some neurons of the hypothalamic and midbrain DA systems contain somatostatin (SOM) or neurotensin (NT), and, in the LSA, the distribution of fibers containing...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229030
更新日期：1993-01-01 00:00:00
abstract：:The cortical anatomical substrates by which visual information may influence the frontal areas controlling reaching movements to visual targets were studied in monkeys. A reaching task was employed to characterize the arm-related regions of the frontal lobe. Injections of retrograde tracers into these physiologically ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228707
更新日期：1993-01-01 00:00:00
abstract：:The present study characterizes expression of calbindin D28K (CB-D28K) and parvalbumin (PV) in ventral forebrain (VFB) grafts placed in the neocortex of adult rats bearing quisqualic acid lesions to the nucleus basalis magnocellularis. Three to nine months after transplantation surgery, rats were killed for in situ hy...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050311
更新日期：1998-02-01 00:00:00
abstract：:Sources of primary afferent depolarization (PAD) of skin afferents in the sural (Sur) nerve and of group-II muscle afferents in the posterior biceps and semitendinosus (PBST) nerve were compared at several sites, about 2 mm apart, within the L7-S2 segments in order to define areas of projection of sacral interneurons ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000429
更新日期：2000-08-01 00:00:00
abstract：:The flexion reflex modulation pattern was investigated in nine people with a chronic spinal cord injury during stepping using body weight support on a treadmill and manual assistance by therapists. Body weight support was provided by an upper body harness and was adjusted for each subject to promote the best stepping ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1854-x
更新日期：2009-07-01 00:00:00
abstract：:The action of delta-aminovaleric acid (AVA) on the muscle relaxant properties of baclofen, a GABAB receptor agonist, was investigated in two experimental models: (1) the pathologically increased muscle tone of the gastrocnemius muscle in spastic mutant Han-Wistar rats and (2) the Hoffmann (H)-reflex recorded from plan...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00247610
更新日期：1988-01-01 00:00:00
abstract：:Previous studies have shown that the "synaptic" bodies of mammalian pinealocytes are a heterogeneous group of organelles. Whereas "synaptic" ribbons (SR) exhibit a day/night rhythm with small numbers during daytime and high numbers at night, the so-called "synaptic" spherules (SS) show species-specific differences in ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236214
更新日期：1987-01-01 00:00:00
abstract：:The mechanisms of the clasp-knife reflex were studied in the soleus muscle of an animal model, the decerebrate cat with a dorsal hemisection of the lower thoracic cord. The reflex is shown to be autogenetic, and to depend on muscle length in keeping with previous suggestions. However, the magnitude of the inhibition i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF01474257
更新日期：1979-09-01 00:00:00
abstract：:The aim of this study was to evaluate the modulation of muscle activity during locomotor-like movements by different walking speeds in subjects with a motor complete spinal cord injury (SCI) compared to actively--and passively-walking control subjects without neurological deficit. Stepping movements on a treadmill wer...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0509-4
更新日期：2006-10-01 00:00:00
abstract：:The dual visuomotor channel theory proposes that prehension consists of a Reach that transports the hand in relation to an object's extrinsic properties (e.g., location) and a Grasp that shapes the hand to an object's intrinsic properties (e.g., size and shape). In central vision, the Reach and the Grasp are integrate...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3945-6
更新日期：2014-09-01 00:00:00
abstract：:The interaction between pain and the motor system is well-known, with past studies showing that pain can alter corticomotor excitability and have deleterious effects on motor learning. The aim of this study was to better understand the cortical mechanisms underlying the interaction between pain and the motor system. E...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-017-4880-0
更新日期：2017-04-01 00:00:00
abstract：:Evidence suggests that there are positive effects of exercise on learning and memory. Moreover, some studies have demonstrated that forced exercise plays the role of a stressor. This study was aimed at investigating the effects of different timing of exercise and exercise withdrawal on memory, and serum and hippocampa...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4349-y
更新日期：2015-10-01 00:00:00
abstract：:The acuities of X-cells from the dorsal lateral geniculate nucleus (LGN) were measured in five cats raised with a convergent strabismus, surgically induced by tenotomy. The acuities of cells driven by the strabismic eye were not significantly different from the acuities of cells driven by the non-deviating eye over th...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00250595
更新日期：1988-01-01 00:00:00
abstract：:Successive motor unit (MU) twitches often do not sum linearly. Also, muscle spindle (MS) afferents may react nonlinearly to MU contractions occurring at short intervals. Little data is presently available on the interactions between two (or more) MUs regarding their effects on tension output and MS responses. We have ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237486
更新日期：1986-01-01 00:00:00
abstract：:In drawing a copy of a geometrical shape, a sequence of movements must be produced to represent the sides of the object in the proper spatial relationship. We investigated neural mechanisms of this process by training monkeys to draw (using a joystick) copies of geometrical shapes (triangles, squares, trapezoids and i...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-003-1416-6
更新日期：2003-05-01 00:00:00
abstract：:This study examines the process of learning to walk from a functional perspective. To move forward, one must generate and control propulsive forces. To achieve this, it is necessary to create and tune a distance between the centre of mass (CoM) and the centre of pressure (CoP) along the antero-posterior axis. We hypot...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4378-6
更新日期：2015-10-01 00:00:00
