Neural site of strabismic amblyopia in cats: X-cell acuities in the LGN.

Abstract:

:The acuities of X-cells from the dorsal lateral geniculate nucleus (LGN) were measured in five cats raised with a convergent strabismus, surgically induced by tenotomy. The acuities of cells driven by the strabismic eye were not significantly different from the acuities of cells driven by the non-deviating eye over the range of eccentricities in the visual field studied (from the area centralis to over 20 degrees). The data were also similar to X-cell acuities in the LGN of 3 normal cats. Lowered acuities of LGN X-cells driven by the deviating eye of an esotropic cat in which the strabismus was created by myectomy confirm a previous finding of a retinal locus of amblyopia associated with that preparation. In contrast, the results here implicate the visual cortex as the initial site of the deficit in spatial processing in amblyopia arising from tenotomy strabismus.

journal_name

Exp Brain Res

authors

Gillard-Crewther S,Crewther DP

doi

10.1007/BF00250595

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

503-9

issue

3

eissn

0014-4819

issn

1432-1106

journal_volume

72

pub_type

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