Abstract：
:Early blindness in humans and experimental visual deprivation in animal models are known to induce compensatory somatosensory and/or auditory activation of the visual cortex. An abnormal hydrocephalic cat with extreme malformation of the visual system, born in our breeding colony, rendered a good model system for investigating possible cross-modal compensation in such a pathological case. For comparison, we used normal and neonatally enucleated cats. When introduced to a novel environment, the abnormal cat behaved as if it was completely blind, yet it responded normally to auditory stimuli. As anticipated, single cells in the visual cortex of normal cats responded to visual, but not to auditory stimuli. In the visual cortex of enucleated cats, flashes of light did not elicit field-evoked potentials or single-unit responses. However, several cells did respond to various auditory stimuli. In the remnant visual cortex of the abnormal cat, auditory stimuli evoked field potentials and single-cell responses. Unexpectedly, however, unlike the enucleated cats, in the abnormal cat, flashes of light also elicited field-evoked potentials. Judging by its behavior, it is very likely that this deformed cat had completely lost its ability to perceive images, but had probably retained some sensitivity to light.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Yaka R,Yinon U,Rosner M,Wollberg Zdoi
10.1007/s002219900295keywords:
subject
Has Abstractpub_date
2000-03-01 00:00:00pages
144-8issue
1eissn
0014-4819issn
1432-1106journal_volume
131pub_type
杂志文章abstract：:The main input of the lateral part of the cat's lateralis posterior-pulvinar complex (LP-P) comes from the primary visual cortex. We investigated the response properties of cells in area 17 projecting to the striate-recipient zone (LP1) of the cat's LP-P complex. The cells' receptive fields were stimulated with drifti...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227105
更新日期：1993-01-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/BF00275002
更新日期：1989-01-01 00:00:00
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更新日期：1986-01-01 00:00:00
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pub_type： 临床试验,杂志文章
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更新日期：2003-12-01 00:00:00
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journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050478
更新日期：1998-08-01 00:00:00
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pub_type： 杂志文章
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doi：10.1007/s00221-008-1385-x
更新日期：2008-07-01 00:00:00
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pub_type： 杂志文章
doi：10.1007/s002210050301
更新日期：1998-02-01 00:00:00
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