Abstract:
:Control of velocity in rapid flexion movements of the interphalangeal joint of the thumb was investigated by examining movement trajectories and patterns of activity in the extensor pollicis longus (EPL) and flexor pollicis longus (FPL) muscles. Although velocity was controlled with considerable accuracy, it was not sensed with the same precision. Consistent errors were made when subjects attempted to match the peak velocities under conditions in which the relationship between muscle activity and joint acceleration had been altered, i.e. changing the angle from which movement was initiated or varying the load. Rather than relying on afferent feedback from peripheral sensory receptors for information about velocity during rapid movements, it is suggested that subjects were more likely to base their judgment of velocity on sensations evoked by the voluntary motor command.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Milner TEdoi
10.1007/BF00237406subject
Has Abstractpub_date
1986-01-01 00:00:00pages
99-110issue
1eissn
0014-4819issn
1432-1106journal_volume
62pub_type
杂志文章abstract::We tested the hypothesis that some of the electromyographic (EMG) responses elicited in preactivated forearm muscles by transcranial stimulation of the human motor cortex are produced by activity in a disynaptic corticospinal linkage involving propriospinal-like interneurones with cell bodies in the spinal C3-4 segmen...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229634
更新日期:1996-06-01 00:00:00
abstract::Previous investigations have suggested that the dorsolateral pontine tegmentum (DLP) may be part of a system essential for classical conditioning of the nictitating membrane response. The present study examined CR-related firing patterns of extracellularly-recorded single units in the DLP. Differential conditioning, u...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00243830
更新日期:1986-01-01 00:00:00
abstract::We investigated the extent to which humans can quickly adapt their goal-directed arm movements to perturbed feedback. We predicted that the magnitude of adaptation to a changed relationship between vision and kinesthesia would depend on the type of perturbation, being largest when the perturbation can be generalized w...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1321-4
更新日期:2003-02-01 00:00:00
abstract::The topography of commissural fibers of the prefrontal cortex was studied in the rhesus monkey using autoradiography. Commissural fibers originating in the medial prefrontal and the caudal orbital regions course through the anterior portion of the genu and the rostrum of the corpus callosum, while those from the arcua...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00240516
更新日期:1984-01-01 00:00:00
abstract::Internal models are sensory motor mappings used by the nervous system to anticipate the force requirements of movement tasks. The ability to use internal models likely underlies the development of skillful control of the arm throughout life. It is currently unknown to what extent individuals with hemiparetic stroke ca...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1340-1
更新日期:2003-03-01 00:00:00
abstract::The study aimed to compare the ability of dance and non-dance subjects to perform fine control of a simple heel-raising/lowering movement, and to determine if there are any differences in motor unit activity in the primary plantar flexor muscles during the movement. Subjects were instructed to accurately track a sinus...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-017-5131-0
更新日期:2018-02-01 00:00:00
abstract::Directional preferences have previously been demonstrated during horizontal arm movements. These preferences were characterized by a tendency to exploit interaction torques for movement production at the shoulder or elbow, indicating that the preferred directions depend on biomechanical, and not on visual perception-b...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3766-z
更新日期:2014-02-01 00:00:00
abstract::We examined modulation of transmission in short-latency, distal hindlimb cutaneous reflex pathways during fictive locomotion in 19 decerebrate cats. Fictive stepping was produced either by electrical stimulation of the mesencephalic locomotor region (MLR) or by administration of Nialamide and 1-DOPA to acutely spinali...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00250567
更新日期:1989-01-01 00:00:00
abstract::Pieces of the developing cerebellar anlage were prepared from 13-15 day old rat embryos and transplanted to the cerebellar region of 5-7 and 13-14 day old rat pups. Approximately two months later, sections showed most grafts to consist of both cerebellar cortex, with a typical trilaminar organization, and white matter...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237288
更新日期:1984-01-01 00:00:00
abstract::The aim of this study was to determine the effect of age on the modulation of forces produced by the digits and to determine the effects of practice on the control of these forces in young and older adults. Young (n = 14, 19-28 years) and old (n = 12, 67-75 years) adults used a precision grip to perform a variable for...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-2342-6
更新日期:2005-09-01 00:00:00
abstract::In the base of each temporal lobe in 4 monkeys (Macaca fascicularis) we sectioned the pia mater in an antero-posterior line along the most medial part of the inferior temporal visual association cortex (area TE), lateral to the parahippocampal cortex. This pial section interrupts the blood flow in branches of the post...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228525
更新日期:1991-01-01 00:00:00
abstract::The effect of fatigue on finger force perception within a hand during ipsilateral finger force matching was examined. Thirteen subjects were instructed to match a reference force of an instructed finger using the same or different finger within the hand before and after index finger fatigue. Absolute reference force t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-007-0978-0
更新日期:2007-09-01 00:00:00
abstract::In order to examine the stability and patterning of speech movement sequences, movements of the lip were recorded as subjects produced a phrase at normal, fast, and slow rates. Three methods of analysis were employed. First, a new index of spatiotemporal stability was derived by summing the standard deviations compute...
journal_title:Experimental brain research
pub_type: 临床试验,杂志文章
doi:10.1007/BF00231983
更新日期:1995-01-01 00:00:00
abstract::Motor control tasks like stance or object handling require sensory feedback from proprioception, vision and touch. The distinction between tactile and proprioceptive sensors is not frequently made in dynamic motor control tasks, and if so, mostly based on signal latency. We previously found that force control tasks en...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3341-z
更新日期:2013-02-01 00:00:00
abstract::Visual information regarding limb location can override proprioceptive information when there is conflict between the two-a phenomenon referred to as visual capture. In three experiments, we employed the "mirror illusion," in which the perceived location of one's hand is influenced by the visual information specified ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2445-6
更新日期:2010-12-01 00:00:00
abstract::The response of 835 click-sensitive neurons in the inferior colliculus (IC) to ramp frequency modulated (FM) tones was studied in the anaesthetized rat. More than 70% of the cells were sensitive to the FM sound, and over 25% were "FM specialized". Systematic variations of the stimulus parameters showed that sweep velo...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229838
更新日期:1991-01-01 00:00:00
abstract::When the head rotates, vestibulocollic reflexes counteract the rotation by causing contraction of the neck muscles that pull against the imposed motion. With voluntary head rotations, these same muscles contract and assist the movement of the head. The purpose of this study was to determine if an infinite variety of m...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF02259112
更新日期:1992-01-01 00:00:00
abstract::We compared pursuit responses to 2D target motion in three separate conditions: predictable, randomised and randomised with timing cues. The target moved on a continuous quadrilateral path in which right-angle direction changes allowed anticipatory eye acceleration and deceleration in orthogonal axes to be assessed. R...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-014-4164-x
更新日期:2015-03-01 00:00:00
abstract::We investigated the effect of musical expertise on sensitivity to asynchrony for drumming point-light displays, which varied in their physical characteristics (Experiment 1) or in their degree of audiovisual congruency (Experiment 2). In Experiment 1, 21 repetitions of three tempos x three accents x nine audiovisual d...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-009-1817-2
更新日期:2009-09-01 00:00:00
abstract::Local anesthetic may cause neurotoxicity in developing neurons. In this study, we examined the molecular mechanisms of microRNA-210 (miR-210) in regulating bupivacaine-induced dorsal root ganglia (DRG) neurotoxicity in vitro. Young mouse (P30) DRG explants were cultured in vitro and treated with 5 mM bupivacaine to in...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4513-4
更新日期:2016-04-01 00:00:00
abstract::We studied the development of information-movement couplings in a ball-bouncing task with a special interest in how space- and time-related information is used by people of different ages. Participants from four age groups (children aged 7-8, 9-10 and 11-12 years, and adults) performed a virtual ball-bouncing task in ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-015-4443-1
更新日期:2016-01-01 00:00:00
abstract::Electron microscopic examination of the monkey lateral geniculate nucleus, pars dorsalis (LGNd) reveals the occurrence of synaptic contacts between profiles belonging to interneurons (I-cells). Almost all combinations are observed, namely, axodendritic, dendrodendritic, dendrosomatic and somatodendritic, the most freq...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237322
更新日期:1976-05-10 00:00:00
abstract::Recent evidence suggests that brain injury can impair the ability to independently activate shoulder and elbow muscles. We hypothesized that if muscle activation patterns are constrained, then brain-injured subjects should not be able to accurately grade initial hand movement direction during reaching toward a broad r...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1055-3
更新日期:2002-04-01 00:00:00
abstract::In the thalamic ventrobasal complex (VB) of the cat, effects of electrical stimulation of the pyramidal tract (PT) upon activities of 112 relay cells and 18 internuncial cells were examined. Single PT shocks to the cerebral peduncle elicited short-latency discharges in 31 relay cells (mean latency, 1.4 +/- 0.5 msec). ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00234770
更新日期:1975-03-27 00:00:00
abstract::In recordings from two awake, behaving macaque monkeys we found that neurons in the crown of the prelunate gyrus differed in their responsiveness to simple visual stimuli. Neurons in the posterior part of the gyrus (area V4) responded strongly to stationary or moving bars, while neurons in the anterior part (area V4A)...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1112-y
更新日期:2002-07-01 00:00:00
abstract::A size-weight illusion was used to examine the role of visual cues in the programming of manipulative forces during the lifting of test objects utilizing the precision grip. Three different boxes of equal weight and unequal size were lifted. These were equipped with an instrumented grip handle to measure the employed ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00229824
更新日期:1991-01-01 00:00:00
abstract::The blood-brain barrier (BBB) arises from epithelial-like tight junctions that virtually cement adjoining capillary endothelium together in the brain microvasculature. Several experimental manipulations have been shown able to increase the permeability of brain capillaries, by altering endothelial cell membrane integr...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/pl00005725
更新日期:1997-07-01 00:00:00
abstract::Morphometric changes have been studied at the mouse neuromuscular junction (NMJ) as a function of the frequency of stimulation. In vivo stimulation was made at either 10, 25, 50 or 100 Hz. No significant change in the area of NMJ profiles is observed after stimulation. This indicates that stimulation does not change t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00237590
更新日期:1986-01-01 00:00:00
abstract::Owing to the flexibility and redundancy of neuromuscular and skeletal systems, humans can trace the same hand trajectory in space with various arm configurations. However, the joint trajectories of typical unrestrained movements tend to be consistent both within and across subjects. In this paper we propose a method t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-005-0039-5
更新日期:2005-12-01 00:00:00
abstract::Saccade characteristics in response to moving and stationary targets were studied in three monkeys (Macaca mulatta) that had been trained to look at a target, which after an initial jump either remained in place or moved forward or backward with constant velocity (10 degrees /s). Eye movements were recorded using a se...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2070-3
更新日期:2005-02-01 00:00:00