Abstract：
:Mammalian muscle spindles show persistent after-effects following conditioning stretch or fusimotor stimulation. Most previous observations have been carried out on primary endings of spindles and using dynamic fusimotor stimulation. We report here observations on after-effects produced either by conditioning stretch or by static fusimotor stimulation on the responses of primary and secondary endings to a slow test stretch during which a brief burst of static fusimotor stimulation is applied. We find that the response to the test burst is large if the muscle is kept short after conditioning but it becomes depressed if the muscle is held stretched for 3 s following conditioning. We attribute these effects to the presence of stable cross-bridges between actin and myosin filaments in intrafusal fibres. We conclude that, qualitatively, after-effects using static fusimotor testing are the same as with dynamic fusimotor testing and this must be taken into account when providing an explanation for the phenomenon.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Proske U,Morgan DLdoi
10.1007/BF00237676subject
Has Abstractpub_date
1985-01-01 00:00:00pages
166-70issue
1eissn
0014-4819issn
1432-1106journal_volume
59pub_type
杂志文章abstract：:In cats, 107 area 18 neurones with identified FR type, 10-50 degrees from the visual axis, were tested for the influence of direction, velocity and amplitude of movement. These three parameters are believed to be the primary parameters of a movement analysing system. 94% of the neurones were influenced by the directio...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237863
更新日期：1977-10-24 00:00:00
abstract：:This kinematic study aimed to determine whether color is a stimulus property involved in the control of reaching-grasping movements. Subjects reached and grasped a target-object, located either on the right or on the left of the subject's midline. A distractor, placed along the subject's midline, could be randomly pre...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000639
更新日期：2001-03-01 00:00:00
abstract：:Internal models are sensory motor mappings used by the nervous system to anticipate the force requirements of movement tasks. The ability to use internal models likely underlies the development of skillful control of the arm throughout life. It is currently unknown to what extent individuals with hemiparetic stroke ca...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-002-1340-1
更新日期：2003-03-01 00:00:00
abstract：:During cerebral neocortical development, excitatory neurons are generated from radial glial cells in the ventricular zone (VZ) or from secondary progenitor cells in the subventricular zone (SVZ); these neurons then migrate toward the pial surface. We have observed that post-mitotic neurons generated directly in the VZ...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-011-2933-3
更新日期：2012-01-01 00:00:00
abstract：:In order to further our understanding of action-blindsight, four hemianopic patients suffering from visual field loss contralateral to a unilateral occipital lesion were compared to six healthy controls during a double task of verbally reported target detection and saccadic responses toward the target. Three oculomoto...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3803-y
更新日期：2014-03-01 00:00:00
abstract：:Human observers are experts at visual face recognition due to specialized visual mechanisms for face processing that evolve with perceptual expertize. Such expertize has long been attributed to the use of configural processing, enabled by fast, parallel information encoding of the visual information in the face. Here ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3463-y
更新日期：2013-05-01 00:00:00
abstract：:Chronic loss of vestibular function modifies the role of neck afferents in human perception of self-motion. We characterized this change by comparing the self-motion perception of patients with chronic vestibular loss (Ps) to that of normal subjects (Ns). Stimuli consisted of sinusoidal horizontal rotations (0.025-0.4...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227147
更新日期：1993-01-01 00:00:00
abstract：:The mesencephalic dopamine (DA) cell system was examined in mice homozygous and heterozygous for the weaver (wv) gene and in wild-type controls to estimate the extent of cell losses associated with the genetically determined central DA deficiency observed in weaver homozygotes. Animals of the three genotypes (+/+, wv/...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00248351
更新日期：1988-01-01 00:00:00
abstract：:In the present study, we examined the effects of explicit knowledge, obtained through instruction or spontaneous detection, on the transfer of visuomotor sequence learning. In the learning session, participants learned a visuomotor sequence, via trial and error. In the transfer session, the order of the sequence was r...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-017-4933-4
更新日期：2017-06-01 00:00:00
abstract：:This study employed neurophysiological methods to relate the condition of the corticospinal system with the voluntary control of lower-limb muscles in persons with motor-incomplete spinal cord injury. It consisted of two phases. In a group of ten healthy subjects, single and paired transcranial magnetic stimulation (T...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2190-9
更新日期：2005-06-01 00:00:00
abstract：:Generally, increases in cortical activity go in parallel with negative shifts and decreases with positive shifts of cortical d.c. potentials. The aim of the present investigation was to test the effects of the inhibitory transmitter gamma-aminobutyric acid (GABA) and of GABA receptor agonists on cortical d.c. potentia...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005614
更新日期：1997-03-01 00:00:00
abstract：:Neuron activity was recorded in monkey cerebral cortex during a visually guided reaching task. Cells located in the banks of the arcuate sulcus at its curvature changed their activity during the period in which the monkey saw a food reward in a certain position, but before it moved to retrieve the reward. A role of th...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238755
更新日期：1981-01-01 00:00:00
abstract：:In sensory saltation, first reported by Geldard and Sherrick (Science 178:178-179, 1972), a stimulus is displaced towards a second one following closely in time and space as a function of the delay between the stimuli. The distance between stimulus locations is restricted by the extension of sensory fields in the prim...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0190-z
更新日期：2006-03-01 00:00:00
abstract：:It is known that, when both forearms are rotated rhythmically and symmetrically, the dominant hand leads in time by about 25 ms, irrespective of movement speed. Positron emission tomography was used to test the hypothesis that the asynchrony results from a functional hemispheric asymmetry. We found that in normal, adu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050428
更新日期：1998-06-01 00:00:00
abstract：:Central conduction time is the time for an afferent volley to traverse the central pathways of a sensory system. In the present study, central auditory conduction time (CACT) was calculated for the rat, the first such formal measurement in any animal. Brainstem auditory evoked potentials (BAEPs) were recorded simultan...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228892
更新日期：1990-01-01 00:00:00
abstract：:The purpose of this study is to analyze the coordination patterns of the elevation angles of lower limb segments following the onset of unsupported walking in children and to look for the existence of a planar covariation rule as previously described in adult human locomotion. The kinematic patterns of locomotion were...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s002210000663
更新日期：2001-04-01 00:00:00
abstract：:Pax genes are important modulators of CNS development. Pax7 and Pax6 polarise the neural tube and regionalise the brain. Pax7 is pivotal in specifying the superior colliculus/tectum, an important centre for integration of visuomotor responses and a target for Pax6+ retinal ganglion cell axons during retinocollicular m...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0735-9
更新日期：2007-04-01 00:00:00
abstract：:We investigated the effect of different spatial and temporal parameters on the saccadic reaction times (SRTs) of the antisaccades and on the frequency and the SRTs of erratic prosaccades in five adult human subjects. The subjects were instructed to aim their saccades to the side opposite to where a visual go-stimulus ...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/pl00005749
更新日期：1997-09-01 00:00:00
abstract：:The aim of the study was to investigate grip-load force regulation in Huntington's disease (HD) patients as compared to control subjects during the performance of a manipulative task that required rhythmical unimanual or bimanual isodirectional/non-isodirectional actions in the sagittal plane. Results showed that the ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0992-6
更新日期：2002-04-01 00:00:00
abstract：:Rats probe objects with their whiskers and make decisions about sizes, shapes, textures and distances within a few tens of milliseconds. This perceptual analysis requires the processing of tactile high-frequency object components reflecting surface roughness. We have shown that neurons in the barrel cortex of rats enc...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4357-y
更新日期：2015-10-01 00:00:00
abstract：:Threshold elevation in the periphery of the visual field as a consequence of repetitive stimulation can be abolished by stimulating a mirror-symmetric position in the contralateral visual half-field. A patient suffering from a congenital malformation of the right superior colliculus did not exhibit threshold elevation...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236761
更新日期：1979-05-02 00:00:00
abstract：:Everyday life requires the ability to flexibly switch between tasks. Often, task switching is accompanied by concurrent cognitive activities that compete for limited attentional resources. This study aimed to characterize the effects of attentional load on task switching. In experiment 1, participants performed an int...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3452-1
更新日期：2013-06-01 00:00:00
abstract：:Vibratory stimulation of the neck muscles can elicit illusory drift of a visual target; after vibration stops, motion in the opposite direction is perceived. This motion aftereffect (MAE) could be due to adaptation of proprioceptive mechanisms that encode head orientation, or at a stage where visual and proprioceptive...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0910-7
更新日期：2007-07-01 00:00:00
abstract：:At a descriptive level, prehension movements can be partitioned into three components ensuring, respectively, the transport of the arm to the vicinity of the target, the orientation of the hand according to object tilt, and the grasp itself. Several authors have suggested that this analytic description may be an opera...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228557
更新日期：1996-07-01 00:00:00
abstract：:The aim of the present study was to further investigate the contribution of primary muscle spindle feedback to proprioception and higher brain functions, such as movement trajectory recognition. For this purpose, complex illusory movements were evoked in subjects by applying patterns of muscle tendon vibration mimicki...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-005-0325-2
更新日期：2006-06-01 00:00:00
abstract：:Cells in cat's area 17 respond optimally if elongated contrasts are presented at a certain angle or orientation with respect to the retina, or to the visual field, respectively (Hubel and Wiesel, 1962). The preferred orientation and the range of orientation sensitivity of cells in close proximity to one another have b...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00234062
更新日期：1975-12-22 00:00:00
abstract：:Tactile motion perception is one of the most important functions for realizing a delicate appreciation of the tactile world. To explore the neural dynamics of motion processing in the brain, the motion adaptation phenomenon can be a useful probe. Tactile motion aftereffects (MAE), however, have not been reported in a ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0979-z
更新日期：2007-07-01 00:00:00
abstract：:Antisaccades have not only longer latencies but also lower peak velocities than prosaccades. It is not known whether these latency and velocity differences are related. Studies of non-human primates suggest that prosaccade peak velocity declines as latency from target appearance increases. We examined whether a simila...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-1940-z
更新日期：2004-11-01 00:00:00
abstract：:In anesthetized and paralyzed cats, the normal alignment of the visual axes is disturbed by paralysis of the eye muscles. Thus, the separation between paired receptive fields of binocular cells in visual cortex is increased (paralysis squint). This increased separation is normally tolerated by the majority of visuocor...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00249802
更新日期：1987-01-01 00:00:00
abstract：:Peripheral sensory-motor neuropathy is one of the most frequent side effects of vincristine (VCR) administration, which often limits its usefulness in the treatment of a wide range of neoplastic diseases. The purpose of this work is to study VCR neurotoxicity in experimental animals from clinical, electrophysiological...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0499-2
更新日期：2006-08-01 00:00:00
