当前位置： SCI文献检索 > EXPERIMENTAL BRAIN RESEARCH期刊下所有文献 > Identifying brain regions for integrative sensorimotor processing with ankle movements.

Identifying brain regions for integrative sensorimotor processing with ankle movements.

Abstract：

:The objective of this study was to define cortical and subcortical structures activated during both active and passive movements of the ankle, which have a fundamental role in the physiology of locomotion, to improve our understanding of brain sensorimotor integration. Sixteen healthy subjects, all right-foot dominant, performed a dorsi-plantar flexion task of the foot using a custom-made wooden manipulandum, which enabled measurements of the movement amplitude. All subjects underwent a training session, which included surface electromyography, and were able to relax completely during passive movements. Patterns of activation during active and passive movements and differences between functional MRI (fMRI) responses for the two types of movement were assessed. Regions of common activation during the active and passive movements were identified by conjunction analysis. We found that passive movements activated cortical regions that were usually similar in location to those activated by active movements, although the extent of the activations was more limited with passive movements. Active movements of both feet generated greater activation than passive movements in some regions (such as the ipsilateral primary motor cortex) identified in previous studies as being important for motor planning. Common activations during active and passive movements were found not only in the contralateral primary motor and sensory cortices, but also in the premotor cortical regions (such as the bilateral rolandic operculum and contralateral supplementary motor area), and in the subcortical regions (such as the ipsilateral cerebellum and contralateral putamen), suggesting that these regions participate in sensorimotor integration for ankle movements. In future, similar fMRI studies using passive movements have potential to elucidate abnormalities of sensorimotor integration in central nervous system diseases that affect motor function.

journal_name

Exp Brain Res

journal_title

Experimental brain research

authors

Ciccarelli O,Toosy AT,Marsden JF,Wheeler-Kingshott CM,Sahyoun C,Matthews PM,Miller DH,Thompson AJ

doi

10.1007/s00221-005-2335-5

keywords:

subject

Has Abstract

pub_date

2005-09-01 00:00:00

pages

31-42

issue

eissn

0014-4819

issn

1432-1106

journal_volume

166

pub_type

杂志文章

在线工具

Identifying brain regions for integrative sensorimotor processing with ankle movements.