Premovement brain activity in a bimanual load-lifting task.

Abstract:

:Even the simplest volitional movements must be precisely coordinated with anticipatory postural adjustments. Little is currently known about the neural networks that coordinate these adjustments in healthy adults. We measured brain activity prior to movement during a bimanual load-lifting task, designed to elicit anticipatory adjustments in a restricted and well-defined set of musculature in the arm. Electroencephalography and magnetoencephalography brain measurements were obtained from eleven participants while they performed a bimanual load-lifting task that required precise inter-limb coordination. Anticipatory biceps brachii inhibition in the loaded arm was associated with a robust desynchronization of the beta rhythm. Beamforming analyses localized beta band responses to the parietal lobules, pre- and post-central gyri, middle and medial frontal gyri, basal ganglia and thalamus. The current study shows that premovement brain activity in a bimanual load-lifting task can be imaged with magnetoencephalography. Future experiments will partition out brain activity associated with anticipatory postural adjustments and volitional movements. The experimental paradigm will also be useful in the study of motor function in patients with developmental or degenerative disorders.

journal_name

Exp Brain Res

authors

Ng TH,Sowman PF,Brock J,Johnson BW

doi

10.1007/s00221-010-2470-5

subject

Has Abstract

pub_date

2011-01-01 00:00:00

pages

189-201

issue

2

eissn

0014-4819

issn

1432-1106

journal_volume

208

pub_type

杂志文章
  • Direct visualization of death of neurones projecting to specific targets in the developing rat brain.

    abstract::The fluorescent dye diamidino yellow was injected into parts of the developing visual and auditory systems in the rat. The dye was retrogradely transported by projecting neurones and was found to stain pyknotic profiles within the labelled cell populations. It is thus possible to visualize directly the death of neuron...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00228865

    authors: Harvey AR,Robertson D,Cole KS

    更新日期:1990-01-01 00:00:00

  • Sites of action of testosterone in the brain of the female primate.

    abstract::Thaw-mount autoradiography was used to map target neurons for tritiated steroids in the brains of ovariectomized rhesus monkeys. In five females, studies were performed 60 min after the administration of 3H-estradiol. Of these, two females were pretreated for five days with daily injections of 2 mg testosterone propio...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00235647

    authors: Rees HD,Bonsall RW,Michael RP

    更新日期:1986-01-01 00:00:00

  • Cyclic modulation of the H-reflex in a wrist flexor during rhythmic flexion-extension movements of the ipsilateral foot.

    abstract::In 12 subjects, each sitting on an armchair with the right forearm prone, the H-reflex elicited in the resting flexor carpi radialis muscle underwent cyclic excitability changes correlated with rhythmic flexion-extension movements of the ipsilateral foot (frequency of oscillations between 1.5 and 2.5 Hz). During foot ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s002210050297

    authors: Baldissera F,Cavallari P,Leocani L

    更新日期:1998-02-01 00:00:00

  • A lower visual field advantage for endpoint stability but no advantage for online movement precision.

    abstract::It has been proposed that visually guided reaching movements performed in the lower visual field (LVF) of peripersonal space are more effective and efficient than their upper visual field (UVF) counterparts (Danckert and Goodale 2001). In the present investigation we sought to determine whether this purported visual f...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-006-0386-x

    authors: Krigolson O,Heath M

    更新日期:2006-03-01 00:00:00

  • An object-centred reference frame for control of grasping: effects of grasping a distractor object on visuomotor control.

    abstract::Previous evidence based on perceptual integration and arbitrary responses suggests extensive cross-modal links in attention across the various modalities. Attention typically shifts to a common location across the modalities, despite the vast differences in their initial coding of space. An issue that remains unclear ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-005-0240-6

    authors: Patchay S,Haggard P,Castiello U

    更新日期:2006-04-01 00:00:00

  • Anticipatory Postural Adjustments associated with reaching movements are programmed according to the availability of visual information.

    abstract::During goal-directed arm movements, the eyes, head, and arm are coordinated to look at and reach the target. We examined whether the expectancy of visual information about the target modifies Anticipatory Postural Adjustments (APAs). Ten standing subjects had to (1) move the eyes, head and arm, so as to reach, with bo...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-017-4898-3

    authors: Esposti R,Bruttini C,Bolzoni F,Cavallari P

    更新日期:2017-05-01 00:00:00

  • Nucleus accumbens and preoptic area stimulation: tuberoinfundibular single unit responses, modulation of electrical activity and gonadotrophin secretion.

    abstract::Single unit activity was recorded from tuberoinfundibular neurones in urethane-anaesthetized pro-oestrous rats. Responses following single shock (0.2 Hz) stimulation of the preoptic area/anterior hypothalamus (PO/AH) or nucleus accumbens (ACB) were recorded and computed for 137 single units. More cells were shown, by ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00236546

    authors: Saphier DJ

    更新日期:1985-01-01 00:00:00

  • Neurophysiological properties of the retinal ganglion cell classes of the Cuban treefrog, Hyla septentrionalis.

    abstract::The properties of the retinal ganglion cell classes in the cuban treefrog Hyla septentrionalis were studied qualitatively and quantitatively. In the superficial layers of the optic tectum three main classes of afferent optic nerve fibers could be distinguished, class-1*, class-3 and class-4 neurons. Hyla displays a mo...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00279659

    authors: Grüsser-Cornehls U

    更新日期:1988-01-01 00:00:00

  • Age-related changes in grasping force modulation.

    abstract::The aim of this study was to determine the effect of age on the modulation of forces produced by the digits and to determine the effects of practice on the control of these forces in young and older adults. Young (n = 14, 19-28 years) and old (n = 12, 67-75 years) adults used a precision grip to perform a variable for...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-005-2342-6

    authors: Voelcker-Rehage C,Alberts JL

    更新日期:2005-09-01 00:00:00

  • Cognitive spatial-motor processes. 2. Information transmitted by the direction of two-dimensional arm movements and by neuronal populations in primate motor cortex and area 5.

    abstract::We measured the amount of information transmitted by the direction of two-dimensional (2-D) arm movements of human subjects, and by neuronal populations in the motor cortex and area 5 of monkeys. We also compared the information transmitted by a motor cortical population when the predictability of the direction of mov...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00247577

    authors: Georgopoulos AP,Massey JT

    更新日期:1988-01-01 00:00:00

  • The role of attention on the integration of visual and inertial cues.

    abstract::The extent to which attending to one stimulus while ignoring another influences the integration of visual and inertial (vestibular, somatosensory, proprioceptive) stimuli is currently unknown. It is also unclear how cue integration is affected by an awareness of cue conflicts. We investigated these questions using a t...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-009-1767-8

    authors: Berger DR,Bülthoff HH

    更新日期:2009-09-01 00:00:00

  • Response requirements modulate tactile spatial congruency effects.

    abstract::Several recent studies have provided support for the view that tactile stimuli/events are remapped into an abstract spatial frame of reference beyond the initial somatotopic representation present in the primary somatosensory cortex. Here, we demonstrate for the first time that the extent to which this remapping of ta...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-008-1510-x

    authors: Gallace A,Soto-Faraco S,Dalton P,Kreukniet B,Spence C

    更新日期:2008-11-01 00:00:00

  • Direct inhibitory synaptic linkage of pontomedullary reticular burst neurons with abducens motoneurons in the cat.

    abstract::1. Unit spikes of burst neurons were extracellularly recorded in the pontomedullary reticular formation of the cat. These neurons were identified by their burst activity coincident with the quick inhibitory phase of the contralateral abducens nerve during vestibular nystagmus and their antidromic activation from the c...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00235558

    authors: Hikosaka O,Igusa Y,Nakao S,Shimazu H

    更新日期:1978-11-15 00:00:00

  • Sensory substitution information informs locomotor adjustments when walking through apertures.

    abstract::The study assessed the ability of the central nervous system (CNS) to use echoic information from sensory substitution devices (SSDs) to rotate the shoulders and safely pass through apertures of different width. Ten visually normal participants performed this task with full vision, or blindfolded using an SSD to obtai...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-013-3809-5

    authors: Kolarik AJ,Timmis MA,Cirstea S,Pardhan S

    更新日期:2014-03-01 00:00:00

  • Enhanced sensitivity to echo cues in blind subjects.

    abstract::Many studies have reported that blind people compensate for their visual deficit by sharpening auditory processes. Here we compare the sensitivity to echo cues between blind and sighted subjects. In the first experiment, the blind subjects were more accurate than the sighted subjects in localizing an object on the bas...

    journal_title:Experimental brain research

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00221-005-2329-3

    authors: Dufour A,Després O,Candas V

    更新日期:2005-09-01 00:00:00

  • Asymmetric transfer of sound localization learning between indistinguishable interaural cues.

    abstract::Learning in perceptual tasks is typically highly specific to the trained stimulus parameters. However, can learning be specific to a stimulus parameter that is perceptually indistinguishable from another? We assessed this question using a perceived sound location task in which the perceived sound location was created ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-014-3863-7

    authors: Sand A,Nilsson ME

    更新日期:2014-06-01 00:00:00

  • Functional organization in the cat's pulvinar complex.

    abstract::The responses of 192 single units in the cat's pulvinar-complex, comprising the inferior, medial and lateral pulvinar nuclei, were studied in paralysed cats, lightly anaesthetized with N2O/O2 supplemented with pentobarbitone. About 60% of the cells were visually driven and their receptive fields classified as either d...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00235804

    authors: Mason R

    更新日期:1978-01-18 00:00:00

  • Grip force control during gait initiation with a hand-held object.

    abstract::When walking with a hand-held object, grip force is coupled in an anticipatory manner to changes in inertial force resulting from the accelerations and decelerations of gait. However, it is not known how grip and inertial forces are organized at the onset of gait, and if the two forces are coupled in the early phases ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-008-1476-8

    authors: Diermayr G,Gysin P,Hass CJ,Gordon AM

    更新日期:2008-09-01 00:00:00

  • Adaptation and generalization in acceleration-dependent force fields.

    abstract::Any passive rigid inertial object that we hold in our hand, e.g., a tennis racquet, imposes a field of forces on the arm that depends on limb position, velocity, and acceleration. A fundamental characteristic of this field is that the forces due to acceleration and velocity are linearly separable in the intrinsic coor...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-005-0163-2

    authors: Hwang EJ,Smith MA,Shadmehr R

    更新日期:2006-03-01 00:00:00

  • Gait capacity affects cortical activation patterns related to speed control in the elderly.

    abstract::Functional decline in locomotion is common among the elderly, and the prevalence of gait disorders increases with age. Recently, increasing interest has been focused on the influence of age-related decline in brain function and neurological disorders such as dementia and Alzheimer's disease on gait capacity. However, ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-008-1643-y

    authors: Harada T,Miyai I,Suzuki M,Kubota K

    更新日期:2009-03-01 00:00:00

  • Simple and complex spike activities of Purkinje cells during locomotion in the cerebellar vermal zones of decerebrate cats.

    abstract::In walking cats decerebrated at the premammillary level, single neurone activity of Purkinje cells (P-cells) with long corticofugal axons was recorded in the cerebellar vermis. The P-cells (N = 145) were identified as they showed spontaneous simple and complex spikes and also antidromic activation from Deiters' nucleu...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00238886

    authors: Udo M,Matsukawa K,Kamei H,Minoda K,Oda Y

    更新日期:1981-01-01 00:00:00

  • Relationship between saccadic eye movements and cortical activity as measured by fMRI: quantitative and qualitative aspects.

    abstract::We investigated the quantitative relationship between saccadic activity (as reflected in frequency of occurrence and amplitude of saccades) and blood oxygenation level dependent (BOLD) changes in the cerebral cortex using functional magnetic resonance imaging (fMRI). Furthermore, we investigated quantitative changes i...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s002210100844

    authors: Kimmig H,Greenlee MW,Gondan M,Schira M,Kassubek J,Mergner T

    更新日期:2001-11-01 00:00:00

  • Dynamics of inter-modality re-weighting during human postural control.

    abstract::Flexible and stable postural control requires adaptation to changing environmental conditions, a process which requires re-weighting of multisensory stimuli. Recent studies, as well as predictions from a computational model, have indicated a reciprocal re-weighting relationship between modalities when a sensory stimul...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-012-3244-z

    authors: Polastri PF,Barela JA,Kiemel T,Jeka JJ

    更新日期:2012-11-01 00:00:00

  • A photothrombotic ring stroke model in rats with remarkable morphological tissue recovery in the region at risk.

    abstract::The photothrombotic ring stroke model with sustained underperfusion followed by late spontaneous reperfusion (Gu et al. 1999) was employed to study its morphological consequences. The exposed crania of adult male Wistar rats were subjected to a ring-shaped laser irradiation beam simultaneously with intravenous erythro...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s002210050672

    authors: Gu WG,Brännström T,Jiang W,Wester P

    更新日期:1999-03-01 00:00:00

  • Ocular dominance in kitten cortex: induced changes of single cells while they are recorded.

    abstract::We have monitored extracellularly individual neurons in the striate cortex of 4-week-old unparalyzed kittens with the aim of changing the ocular dominance of these cells during recording. To do this, we elicited conjugate eye movements using a bipolar stimulating electrode positioned in the internal medullary lamina (...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00236575

    authors: Tsumoto T,Freeman RD

    更新日期:1981-01-01 00:00:00

  • Sequential actions: effects of upcoming perceptual and motor tasks on current actions.

    abstract::Reports of spatial interactions between current and upcoming elements in a movement sequence could be due to intentional planning of a "global" action sequence (i.e., strategic effects), or to unintentional motor planning arising from merely paying attention to upcoming target objects (i.e., interference effects). The...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-015-4511-6

    authors: LeBlanc KA,Westwood DA

    更新日期:2016-04-01 00:00:00

  • Constraining eye movement when redirecting walking trajectories alters turning control in healthy young adults.

    abstract::Humans use a specific steering synergy, where the eyes and head lead rotation to the new direction, when executing a turn or change in direction. Increasing evidence suggests that eye movement is critical for turning control and that when the eyes are constrained, or participants have difficulties making eye movements...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-013-3466-8

    authors: Pradeep Ambati VN,Murray NG,Saucedo F,Powell DW,Reed-Jones RJ

    更新日期:2013-05-01 00:00:00

  • The role of calcium in the repetitive firing of neostriatal neurons.

    abstract::The Ca++ -dependence of the repetitive firing of neostriatal neurons was studied in an in vitro slice preparation of the rat neostriatum. Neuronal firing was evoked by injecting depolarizing currents of 100-200 ms duration. In normal conditions, the mode of firing was tonic and showed very little adaptation. The frequ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00248539

    authors: Galarraga E,Bargas J,Sierra A,Aceves J

    更新日期:1989-01-01 00:00:00

  • Cortical binocularity in convergent strabismus after section of the optic chiasm.

    abstract::In convergent strabismus (esotropia) the spatial asynchrony of the two eye inputs unbalances the interocular interactions, leading to the functional advantage of the nondeviated eye and the inhibition of the esotropic eye. It may be argued that the strabismic suppression, if it is the effect of inhibitory interactions...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-002-1190-x

    authors: Di Stefano M,Gargini C

    更新日期:2002-11-01 00:00:00

  • Humans robustly adhere to dynamic walking principles by harnessing motor abundance to control forces.

    abstract::Human walking dynamics are typically framed in the context of mechanics and energetics rather than in the context of neuromuscular control. Dynamic walking principles describe one helpful theoretical approach to characterize efficient human walking mechanics over many steps. These principles do not, however, address h...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-013-3708-9

    authors: Toney ME,Chang YH

    更新日期:2013-12-01 00:00:00