Abstract：
:Thaw-mount autoradiography was used to map target neurons for tritiated steroids in the brains of ovariectomized rhesus monkeys. In five females, studies were performed 60 min after the administration of 3H-estradiol. Of these, two females were pretreated for five days with daily injections of 2 mg testosterone propionate, one female was pretreated with daily injections of 2 mg dihydrotestosterone propionate, and two females were pretreated with oil vehicle. For comparison, two additional females were administered 3H-testosterone and were killed 30 min later. Following 3H-estradiol administration in females pretreated with oil, there were numerous labeled neurons in the medial preoptic nucleus (n.), anterior hypothalamic area, ventromedial hypothalamic n., arcuate n., bed n. of stria terminalis, lateral septal n., and regions of the amygdala. In females pretreated with testosterone propionate, labeling was virtually abolished in all these areas with the exceptions of the lateral septal n. and arcuate n., presumably because estradiol formed from testosterone competed with 3H-estradiol for estrogen-binding sites. Pretreatment with dihydrotestosterone propionate had no effect on the labeling following the administration of 3H-estradiol. Areas where labeling was blocked, therefore, represent regions where testosterone acted as an estrogen, and it would appear that regional differences in the activity of aromatizing enzymes determine which estrogen target sites in the brain can interact with estrogenic metabolites of testosterone in female primates.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Rees HD,Bonsall RW,Michael RPdoi
10.1007/BF00235647subject
Has Abstractpub_date
1986-01-01 00:00:00pages
67-75issue
1eissn
0014-4819issn
1432-1106journal_volume
63pub_type
杂志文章abstract：:Stimulus-response compatibility (SRC) effects are classified depending on the way that the elements of the stimulus and response sets interact, influencing both the speed and accuracy of the motor response. This is particularly important for social stimuli, such as hands. However, the stimuli used in most SRC studies ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4283-z
更新日期：2015-07-01 00:00:00
abstract：:Previous studies showed that changing forces of gravity as they typically occur during parabolic flights might be responsible for adaptional processes of the CNS. However, until now it has not been differentiated between primary influences of weightlessness and secondary influences due to psycho-physiological factors ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-1187-6
更新日期：2008-03-01 00:00:00
abstract：:Evidence suggests that Parkinson's disease (PD) patients produce large spatial errors when reaching to proprioceptively defined targets. Here, we examined whether these movement inaccuracies result mainly from impaired use of proprioceptive inputs for movement planning mechanisms or from on-line movement guidance. Med...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-015-4343-4
更新日期：2015-09-01 00:00:00
abstract：:Previous findings have suggested that visuomotor programming can make use of learned size information in experimental paradigms where movement kinematics are quite consistent from trial to trial. The present experiment was designed to test whether or not this conclusion could be generalized to a different manipulation...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00221-002-1250-2
更新日期：2002-12-01 00:00:00
abstract：:In order to determine whether neurones in the parvicellular reticular formation are in direct synaptic contact with motoneurones innervating facial muscles, a combined retrograde and anterograde transport study was carried out in the rat. Animals received injections of the retrograde tracer cholera toxin B conjugated ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227336
更新日期：1994-01-01 00:00:00
abstract：:Although postural control requires the integration of different sensory cues, little is known about the role of attentional artifacts on the individual's ability to properly respond to postural challenges. This study investigated the effects of concomitant tasks (cognitive and postural) on the relationship between vis...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4762-x
更新日期：2016-12-01 00:00:00
abstract：:After partial (spared-root) or complete hindlimb deafferentation, locomotion and accurate limb placement during locomotion recover considerably. In the present study movement was studied during and after recovery to determine whether altered motor patterns could substitute for normal ones in the recovery of motor beha...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00248226
更新日期：1988-01-01 00:00:00
abstract：:Adaptation of motor control to weightlessness was studied during a 7-day spaceflight. The maintenance of control of upright posture was examined during a voluntary raising movement of the arm and during the voluntary raising on tiptoe. In order to evaluate the contribution of visual cues, three types of visual situati...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231132
更新日期：1984-01-01 00:00:00
abstract：:The dorsal and ventral streams model of action and perception suggests that reaching to grasp a tool for use involves integrated operation of the two streams. Few attempts have been made to test the limits of this integration in normal subjects. Twenty normal subjects reached for tools or geometric objects which were ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-013-3501-9
更新日期：2013-06-01 00:00:00
abstract：:Excitatory inputs to neurons in the Forel's field H (FFH) related to visually induced vertical saccades from the ipsilateral superior colliculus (SC) were investigated in chronically prepared alert cats. By stimulation of the deep or intermediate layer of the SC, upward augmenting neurons (ANs) and one long-lead downw...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230857
更新日期：1990-01-01 00:00:00
abstract：:Immunohistochemical double staining for gonadotropin releasing hormone (GnRH) and tyrosine hydroxylase (TH) or glutamic acid decarboxylase (GAD) reveals in the septo-preoptic-diagonal band complex of the rat brain close spatial associations between GnRH-immunoreactive perikarya and TH and GAD immunoreactive fibers. In...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238235
更新日期：1983-01-01 00:00:00
abstract：:In a recent study (Whitwell et al. in Exp Brain Res 185:111-119, 2008), we showed that the visuomotor system is "cognitively impenetrable" to the extent that explicit predictive knowledge of the availability of visual feedback on an upcoming trial fails to optimize grasping. The results suggested that the effects of t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1737-1
更新日期：2009-04-01 00:00:00
abstract：:Corticomotor control of the human tongue has been reported to undergo neuroplastic changes following several days of training in a tongue-protrusion task. The aims of the present study were to determine if a 1 h tongue-task training is sufficient to induce signs of neuroplastic changes in the corticomotor pathways, an...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0380-3
更新日期：2006-08-01 00:00:00
abstract：:Joint stiffness measurements during small transient perturbations have suggested that stiffness during movement is different from that observed during posture. These observations are problematic for theories like the classical equilibrium point hypothesis, which suggest that desired trajectories during movement are en...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000598
更新日期：2001-02-01 00:00:00
abstract：:Recently, Kounios J, Frymiare JL, Bowden EM, Fleck JI, Subramaniam K, Parrish TB et al. (2006) found that the mental preparation leading to insight involves heightened activity in medial frontal areas and temporal areas. In the present study, the electrophysiological correlates of successful and unsuccessful Chinese l...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1270-7
更新日期：2008-04-01 00:00:00
abstract：:To determine if PAG stimulation activates serotonin containing neurons in RM, intracellular techniques were used to identify raphe magnus (RM) cells that are excited by antinociceptive periaqueductal gray (PAG) stimulation in the cat. RM neurons that received a monosynaptic EPSP from PAG shock were intracellularly lab...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00279654
更新日期：1988-01-01 00:00:00
abstract：:It is a conservative and reasonable suggestion that implicit functioning, as in blindsight, is simply a weakened, degraded form of normal functioning, especially as the parameters of vision in blindsight are themselves weakened--e.g., acuity is reduced, detection thresholds are raised, chromatic discrimination is coar...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-008-1388-7
更新日期：2009-01-01 00:00:00
abstract：:The saccadic system has been traditionally regarded as two-dimensional (horizontal, vertical) and basically conjugate in the two eyes. However, saccades to disparate targets (e.g., targets in real three-dimensional space that are located in different directions and at different distances) are naturally disconjugate. W...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s002210050529
更新日期：1998-10-01 00:00:00
abstract：:Functional decline in locomotion is common among the elderly, and the prevalence of gait disorders increases with age. Recently, increasing interest has been focused on the influence of age-related decline in brain function and neurological disorders such as dementia and Alzheimer's disease on gait capacity. However, ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-008-1643-y
更新日期：2009-03-01 00:00:00
abstract：:We examined whether there are any adaptive effects on the pursuit initiation after a prolonged exposure to moving visual stimuli. The eye movements of six human subjects were recorded with the scleral search-coil technique or a Dual Purkinje Image Eye-tracker system. A random-dot image appeared on a CRT monitor and mo...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0563-y
更新日期：2006-11-01 00:00:00
abstract：:We studied the finger interactions during maximum voluntary force (MVF) production in flexion and extension in children and adults. The goal of this study was to investigate the age-related changes and flexion-extension differences of MVF and finger interaction indices, such as finger inter-dependency (force enslaving...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0629-x
更新日期：2007-01-01 00:00:00
abstract：:The synapsins are presynaptic membrane-associated proteins involved in neurotransmitter release. They are differentially expressed in tissues and cells of the central and peripheral nervous system. In vestibular end organs of mammals, synapsin I-like immunoreactivity has been reported in efferent and afferent terminal...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-2194-5
更新日期：2005-04-01 00:00:00
abstract：:In this study, we sought to examine the effect of experimentally induced somatic pain on memory. Subjects heard a series of words and made categorization decisions in two different conditions. One condition included painful shocks administered just after presentation of some of the words; the other condition involved ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-019-05534-x
更新日期：2019-07-01 00:00:00
abstract：:Parkinsonian rigidity is characterized by an increased resistance of a joint to externally imposed motion that remains uniform with changing joint angle. Two candidate mechanisms are proposed for the uniformity of rigidity, involving neural-mediated excitation of shortening muscles, i.e., shortening reaction (SR), or ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2594-2
更新日期：2011-04-01 00:00:00
abstract：:Cortical spreading depression (CSD) is influenced by brain excitability and is related to neurological diseases, such as epilepsy. In vitro evidence indicates that neuronal electrical activity is potentiated after CSD. Malnutrition can cause electrophysiological changes in the brain, both in animals and in humans. Her...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2844-3
更新日期：2011-10-01 00:00:00
abstract：:Neural cuffs, implanted around various hindlimb nerves (sural, common peroneal, posterior tibial), were used to deliver brief stimulus trains to unrestrained cats walking on a treadmill. The resulting perturbations of the step cycle were evaluated by analyzing the EMG bursts recorded from the ankle extensors and by hi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00239728
更新日期：1978-06-19 00:00:00
abstract：:Experiments were carried out in urethane-anaesthetised rats to investigate whether GABA is involved in mediating inhibition of neuronal activity in the dorsal half of the periaqueductal grey matter (PAG) after stimulation of the serotonin-containing projection to the PAG from nucleus raphe obscurus (NRO). Multibarrell...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210000627
更新日期：2001-03-01 00:00:00
abstract：:Antisaccades have not only longer latencies but also lower peak velocities than prosaccades. It is not known whether these latency and velocity differences are related. Studies of non-human primates suggest that prosaccade peak velocity declines as latency from target appearance increases. We examined whether a simila...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-004-1940-z
更新日期：2004-11-01 00:00:00
abstract：:Memory for object-place configurations appears to be a common function of the hippocampus in the human and monkey brain. The nature of the spatial information which enters into these object-configural memories in the primate, and the location of the memories themselves, have remained obscure, however. In the rat, much...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s002210050562
更新日期：1998-11-01 00:00:00
abstract：:Fast backward trunk movements are accompanied by hip, knee and ankle rotation which compensate for the backward shift of the center of gravity. The electromyographic pattern associated with the performance of these movements and the associated synergies consists of a fairly synchronous activation of the prime mover (e...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00248275
更新日期：1989-01-01 00:00:00
