Ocular dominance in kitten cortex: induced changes of single cells while they are recorded.

Abstract:

:We have monitored extracellularly individual neurons in the striate cortex of 4-week-old unparalyzed kittens with the aim of changing the ocular dominance of these cells during recording. To do this, we elicited conjugate eye movements using a bipolar stimulating electrode positioned in the internal medullary lamina (IML) of the thalamus. During electrical stimulation of this region, one eye was occluded and the other was visually activated with optimal stimuli. Receptive fields were studied subjectively and objectively and relative response strengths were assessed. Of 42 cells studied in detail, 62% underwent changes on ocular dominance following conditioning periods of, generally, 15-20 min. Control experiments suggest that this plasticity is: age-related; requires both visual stimulation and activation of pathways associated with eye movement; and does not appear to be caused solely by increased arousal levels.

journal_name

Exp Brain Res

authors

Tsumoto T,Freeman RD

doi

10.1007/BF00236575

subject

Has Abstract

pub_date

1981-01-01 00:00:00

pages

347-51

issue

3

eissn

0014-4819

issn

1432-1106

journal_volume

44

pub_type

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