Abstract:
:Previous studies have demonstrated changes in motor memories with the passage of time on the order of hours. We sought to further this work by determining the influence that time on the order of seconds has on motor learning by changing the duration between successive reaches (inter-reach-interval (IRI)). Human subjects made reaching movements to visual targets while holding onto a robotic manipulandum that presented a viscous curl field. We tested four experimental groups that differed with respect to the IRI (0.5, 5, 10 or 20 s). The 0.5 s IRI group performed significantly worse with respect to a learning index than the other groups over the first set of 192 reaches. Each group demonstrated significant learning during the first set. There was no significant difference with respect to the learning index between the 5, 10 and 20 s IRI groups. During the second and third set of 192 reaches the 0.5 s IRI group's performance became indistinguishable from the other groups indicating that with continued training the initial deficit in performance could be overcome.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Francis JTdoi
10.1007/s00221-005-0062-6keywords:
subject
Has Abstractpub_date
2005-11-01 00:00:00pages
128-31issue
1eissn
0014-4819issn
1432-1106journal_volume
167pub_type
杂志文章abstract::How do we achieve unitary perception of an object when it touches two parts of the sensory epithelium that are not contiguous? We investigated this problem with a simple psychophysical task, which we then used in an fMRI experiment. Two wooden rods were moved over two digits positioned to be spatially adjacent. The di...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-010-2306-3
更新日期:2010-07-01 00:00:00
abstract::Although postural control requires the integration of different sensory cues, little is known about the role of attentional artifacts on the individual's ability to properly respond to postural challenges. This study investigated the effects of concomitant tasks (cognitive and postural) on the relationship between vis...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-016-4762-x
更新日期:2016-12-01 00:00:00
abstract::A database of positron-emission-tomography studies published between January 1993 and November 1996 was created to address several questions regarding the function and connectivity of the human anterior cingulate cortex (ACC). Using this database, we have previously reported on the relationship between behavioural var...
journal_title:Experimental brain research
pub_type: 杂志文章,meta分析
doi:10.1007/s002210000400
更新日期:2000-07-01 00:00:00
abstract::We studied in humans the effects of transcranial stimulation of cortical motor areas on the execution of single and sequential rapid arm movements. In a reaction time paradigm with an auditory "go" signal, stimulation given after an auditory tone and before the start of movements delayed the onset but did not affect t...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00233987
更新日期:1994-01-01 00:00:00
abstract::Blinks are known to affect eye movements, e.g., saccades, slow and fast vergence, and saccade-vergence interaction, in two ways: by superimposition of blink-associated eye movements and changes of the central premotor activity in the brainstem. The goal of this study was to determine, for the first time, the effects o...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-004-2040-9
更新日期:2005-02-01 00:00:00
abstract::A double-labelling anatomical strategy employing horseradish peroxidase and tritiated, enzymatically inactive horseradish peroxidase allowed simultaneous visualization of corticospinal neurones and cortical neurones projecting to the dorsal column nuclei in cats. By this approach it is shown that although most cortica...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238364
更新日期:1981-01-01 00:00:00
abstract::We describe the simple-spike activity of Purkinje cells (P cells) in the ventral paraflocculus (VPFL) of behaving monkeys in association with movements of the visual scene that evoke short-latency ocular following responses. One group of P cells discharged maximally for downward motion, and the other for motion toward...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228385
更新日期:1993-01-01 00:00:00
abstract::The study assessed the ability of the central nervous system (CNS) to use echoic information from sensory substitution devices (SSDs) to rotate the shoulders and safely pass through apertures of different width. Ten visually normal participants performed this task with full vision, or blindfolded using an SSD to obtai...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3809-5
更新日期:2014-03-01 00:00:00
abstract::It is a common experience, immediately after the removal of a cast or a splint, to feel motor awkwardness, which is usually attributed to muscular and joint immobilization. However, the same feeling may also be perceived after a brief period of immobilization. We provide evidence that this last effect stems from chang...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-012-3115-7
更新日期:2012-07-01 00:00:00
abstract::It was previously proposed that a linkage between the optokinetic system and the stereoscopic system in higher mammals serves to allow these animals to selectively stabilize those parts of the visual scene which lie in the plane of convergence as the animals move forward in a three-dimensional world (Howard and Ohmi, ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00228902
更新日期:1989-01-01 00:00:00
abstract::The topographical mapping of glial fibrillary acidic protein (GFAP)-immunoreactivity was performed in coronal serial sections of the rat mesencephalon, rhombencephalon and spinal cord. Relative to a background of poor or moderate overall staining of the mesencephalon, the interpeduncular nucleus, substantia nigra and ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230695
更新日期:1989-01-01 00:00:00
abstract::Most studies of rapid orienting gaze shifts generated by combined eye and head movements have focused on an experimental condition in which gaze displacements are started with the subject's eyes in the normal straight-ahead position in the orbit. Such an experimental approach does not permit a clear identification of ...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230204
更新日期:1993-01-01 00:00:00
abstract::The latencies of visually-evoked responses from X- and Y-type neurons of the cat's dorsal lateral geniculate nucleus were measured in a manner that takes account of the inherent variability of discharge in these cells. Latencies measured in this way vary from trial to trial in one cell (and also between cells) by tens...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235998
更新日期:1987-01-01 00:00:00
abstract::The distributions of the kainate/DL-alpha-amino-3-hydroxy-5-methylisoxazolepropionic acid (KA/ AMPA) receptors GluR1 and calcium-activated neutral protease II (calpain II) in the hippocampus of normal and kainate-lesioned rats were studied by immunocytochemistry. There was a reduction in GluR1 immunoreactivity and a s...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF02454147
更新日期:1997-01-01 00:00:00
abstract::The extent and strength of long-distance coupling between locomotor networks in the rostral and caudal spinal cord of larval lamprey were examined with in vitro brain/spinal cord preparations, in which spinal locomotor activity was initiated by chemical microstimulation in the brain, as well as with computer modeling....
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050719
更新日期:1999-05-01 00:00:00
abstract::Single unit activity was studied in the dorsomedial edge of the frontal lobe, above the superior arcuate sulcus in three trained monkeys (Macaca nemestrina). Gaze and head movements were recorded with two magnetic search coils. Discharges preceding spontaneous eye movements in a preferred direction were consistently o...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00238971
更新日期:1985-01-01 00:00:00
abstract::Peak grip aperture has often been used to quantify the influence of illusions on judgments of size for action. However, a larger peak grip aperture need not mean that the object looks larger. It could also mean that it was grasped more carefully. These two possibilities can be distinguished on the basis of the velocit...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-006-0744-8
更新日期:2007-01-01 00:00:00
abstract::The companion article (Sholomenko et al. 1991) described the brainstem locomoter regions in the bird where direct intracerebral injection of a number of putative excitatory neurochemicals, including cholinergic agonists, N-methyl-d-aspartate (NMDA) and Substance P, evoke locomotion. Using the same experimental protoco...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00231753
更新日期:1991-01-01 00:00:00
abstract::Quantitative autoradiography was used to investigate the distribution and effects of gonadal hormones on [3H] muscimol (specific GABAA receptor ligand) binding in the male Japanese quail brain. In gonadally intact Japanese quail brains, [3H] muscimol revealed a heterogeneous distribution with high GABAA receptor level...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00227088
更新日期:1991-01-01 00:00:00
abstract::A series of step-tracking experiments was conducted before, during, and after a 3-week space mission to assess the effects of prolonged microgravity on a non-postural motor-control task. In- and post-flight accuracy was affected only marginally. However, kinematic analyses revealed a considerable change in the underly...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050906
更新日期:1999-12-01 00:00:00
abstract::In the metadata of the original publication of the article. ...
journal_title:Experimental brain research
pub_type: 杂志文章,已发布勘误
doi:10.1007/s00221-019-05476-4
更新日期:2019-02-01 00:00:00
abstract::The photothrombotic ring stroke model with sustained underperfusion followed by late spontaneous reperfusion (Gu et al. 1999) was employed to study its morphological consequences. The exposed crania of adult male Wistar rats were subjected to a ring-shaped laser irradiation beam simultaneously with intravenous erythro...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050672
更新日期:1999-03-01 00:00:00
abstract::The time course of the microglial cell reaction in central nervous system primary sensory projection territories has been examined following peripheral nerve injury in the adult rat using qualitative and quantitative analysis of immunoreactivity with the monoclonal antibody OX-42, which recognises the complement recep...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00230435
更新日期:1993-01-01 00:00:00
abstract::The superior branch of the vestibular nerve containing peripheral axons of primary afferents originating in the lateral and anterior semicircular canals was cut bilaterally in three monkeys (vestibular neurectomy). Vertical and horizontal components of eye position were monitored by electro-oculography (EOG) during di...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00235920
更新日期:1985-01-01 00:00:00
abstract::Slice cultures from the visual cortex of young rats were prepared using the roller culture technique (Gähwiler 1984). After 10 days in vitro the cortical cultures flattened to 1-3 cell layers, surviving for up to 12 weeks. The cultures were organotypically organized, the typical layered structure of the cortex was pre...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00274981
更新日期:1989-01-01 00:00:00
abstract::Parkinson's disease (PD) adversely affects information processing and motor performance. The impact of aerobic exercise on modifying the deleterious effects of PD underlying information and motor control processes is not well established. The primary aim of this project was to determine the effects of an 8-week high i...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-020-06009-0
更新日期:2021-01-04 00:00:00
abstract::Subjects exposed to a rotating environment that perturbs their postural sway show adaptive changes in their voluntary spatially directed postural motion to restore accurate movement paths but do not exhibit any obvious learning during passive stance. We have found, however, that a variable known to characterize the de...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-013-3815-7
更新日期:2014-04-01 00:00:00
abstract::This study compared and contrasted the manifestation of neuropathic pain behaviors in several strains of rats. These included ACI, Brown-Norway, Fischer 344, Lewis, Long-Evans, Sprague-Dawley, and Wistar-Furth, all obtained from Harlan Sprague-Dawley Inc. Comparison was also made between two substrains of Sprague-Dawl...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s002210050886
更新日期:1999-11-01 00:00:00
abstract::The smooth pursuit eye movement system uses retinal information about the image-slip-velocity of the target in order to match the eye-velocity-in-space (i.e., gaze-velocity) to the actual target velocity. To maintain the target image on the fovea during smooth gaze tracking, and to compensate for the long delays invol...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/s00221-002-1088-7
更新日期:2002-07-01 00:00:00
abstract::The acquisition of co-ordination between posture and movement was investigated in human subjects performing a load lifting task. Sitting subjects held their left (postural) forearm in a horizontal position while supporting a 1 kg load via an electromagnet. Perturbation of the postural forearm position consisted of the...
journal_title:Experimental brain research
pub_type: 杂志文章
doi:10.1007/BF00274991
更新日期:1989-01-01 00:00:00