The mirror antisaccade task: direction-amplitude interaction and spatial accuracy characteristics.

Abstract:

:In this study we examined the performance of human subjects in three oculomotor tasks: a visually guided saccade task (VST), a simple antisaccade task (SAT) and a mirror antisaccade task (MAT). The stimulus presentation was identical for all three tasks, and the differentiation of the tasks was based on the instruction given to the subjects. Subjects were instructed to either look at a visually presented target location (visually triggered saccade task), or to look at the opposite direction of the visually presented target (simple antisaccade task) or finally to look at the mirror location opposite to the location of the visually presented target (mirror antisaccade task). The loading of the simple antisaccade task with the addition of the amplitude requirement did not affect the percentage of directional errors but slowed down the onset of antisaccade execution by 19 ms. The amplitude of the directionally correct antisaccade in the mirror antisaccade task showed a significant distortion of the true mirror target location. This dysmetria followed the same qualitative pattern to that observed for the visually guided saccades, i.e., a near-target hypermetria together with a far-target hypometria, but both these features were exaggerated in the mirror antisaccade task. This distorted amplitude modulation of mirror antisaccade amplitude was completely lost in corrected antisaccades that followed a directional error.

journal_name

Exp Brain Res

authors

Evdokimidis I,Tsekou H,Smyrnis N

doi

10.1007/s00221-006-0462-2

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

304-11

issue

2

eissn

0014-4819

issn

1432-1106

journal_volume

174

pub_type

杂志文章
  • Further analysis of presence of peptides in dopamine neurons. Cholecystokinin, peptide histidine-isoleucine/vasoactive intestinal polypeptide and substance P in rat supramammillary region and mesencephalon.

    abstract::Double-labeling combined with elution-restaining immunofluorescence techniques were used to analyze the extent of coexistence among the peptides cholecystokinin (CCK), peptide histidine-isoleucine (PHI)/vasoactive intestinal polypeptide (VIP), substance P and the catecholamine-synthesizing enzyme tyrosine hydroxylase ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00250598

    authors: Seroogy K,Tsuruo Y,Hökfelt T,Walsh J,Fahrenkrug J,Emson PC,Goldstein M

    更新日期:1988-01-01 00:00:00

  • Retrograde tracing studies of subdivisions of the orbicularis oculi muscle in the rhesus monkey.

    abstract::Functionally and anatomically, the orbicularis oculi (OO) muscle can be subdivided in a pretarsal, a preseptal, and an orbital portion. In the rhesus monkey, fluorescent and neuronal retrograde tracing experiments were performed in the pretarsal or the orbital portion of the OO muscle, or both, using fast blue, diamid...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s002210050478

    authors: VanderWerf F,Aramideh M,Otto JA,Ongerboer de Visser BW

    更新日期:1998-08-01 00:00:00

  • Plasticity in the barrel cortex of the adult mouse: effects of peripheral deprivation on GAD-immunoreactivity.

    abstract::The whisker-to-barrel pathway of the adult mouse was used in a study on the effects of peripheral sensory deprivation on GAD-immunoreactivity in the somatosensory cortex. At varying periods of time after removal of a set of vibrissal follicles, mice were processed for immunohistochemistry using an antibody against GAD...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00247346

    authors: Welker E,Soriano E,Van der Loos H

    更新日期:1989-01-01 00:00:00

  • Modulation of somatosensory evoked potentials during force generation and relaxation.

    abstract::This study investigated the modulation of somatosensory evoked potentials (SEPs) during precisely controlled force generation and force relaxation in a visuomotor tracking task. Subjects were instructed to track a target line with a line that represented their own force generated by grip movement with the right hand a...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-012-3082-z

    authors: Wasaka T,Kida T,Kakigi R

    更新日期:2012-06-01 00:00:00

  • Walking performance and its recovery in chronic stroke in relation to extent of lesion overlap with the descending motor tract.

    abstract::We investigated the association between the degree of lesion overlap with the corticospinal tract and walking performance before and after 4-weeks of partial body weight support (PBWS) treadmill training in 18 individuals (ten male, eight female) with a mean age 59 +/- 13 years (mean +/- SD), range 32-74 years, who we...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-007-1237-0

    authors: Dawes H,Enzinger C,Johansen-Berg H,Bogdanovic M,Guy C,Collett J,Izadi H,Stagg C,Wade D,Matthews PM

    更新日期:2008-03-01 00:00:00

  • Effect of acclimation and fixation temperatures on the number of lamellae and periodicity of myelin in fibres of the optic nerve of goldfish.

    abstract::Previous findings from our laboratory have shown that the optic nerves of goldfish acclimated to different temperatures differ considerably in their glycerophospholipid composition. This paper describes changes in the morphology of the nerve with different acclimation and fixation temperatures. Optic nerves of 5 and 2...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00248501

    authors: Matheson DF,Roots BI

    更新日期:1988-01-01 00:00:00

  • The effects of social housing on extinction of fear conditioning in rapid eye movement sleep-deprived rats.

    abstract::Both human and animal research indicate that rapid eye movement sleep (REM) plays an important role in the processing of emotional information. REM is altered after fear conditioning in rats, but this alteration can be mitigated by exposure to a naïve conspecific. In addition, both the housing condition (isolated vs p...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-014-3828-x

    authors: Hunter AS

    更新日期:2014-05-01 00:00:00

  • Sites of action of testosterone in the brain of the female primate.

    abstract::Thaw-mount autoradiography was used to map target neurons for tritiated steroids in the brains of ovariectomized rhesus monkeys. In five females, studies were performed 60 min after the administration of 3H-estradiol. Of these, two females were pretreated for five days with daily injections of 2 mg testosterone propio...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00235647

    authors: Rees HD,Bonsall RW,Michael RP

    更新日期:1986-01-01 00:00:00

  • Predicting favorable and unfavorable consequences of perceptual learning: worsening and the peak shift.

    abstract::Discrimination learning can cause improved and worsened ability to perceive differences. This subsequently affects how stimuli are associated with meanings and behaviors. Here, human listeners were trained with frequency-modulated (FM) tonal sweeps (500-1000 Hz) in a paradigm where one FM rate (8.29 octaves per second...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-016-4866-3

    authors: Wisniewski MG

    更新日期:2017-04-01 00:00:00

  • Bilateral stimulation of the subthalamic nucleus has differential effects on reactive and proactive inhibition and conflict-induced slowing in Parkinson's disease.

    abstract::It has been proposed that the subthalamic nucleus (STN) mediates response inhibition and conflict resolution through the fronto-basal ganglia pathways. Our aim was to compare the effects of deep brain stimulation (DBS) of the STN on reactive and proactive inhibition and conflict resolution in Parkinson's disease using...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-013-3457-9

    authors: Obeso I,Wilkinson L,Rodríguez-Oroz MC,Obeso JA,Jahanshahi M

    更新日期:2013-05-01 00:00:00

  • Simultaneous opposing adaptive changes in cat vestibulo-ocular reflex direction for two body orientations.

    abstract::The specificity of adaptation of vestibulo-ocular reflex direction was examined by exposing cats to combined pitch vestibular rotation and horizontal optokinetic motion at 0.25 Hz, while alternating body position between lying on the left side and lying on the right. The direction of optokinetic motion relative to hea...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00247045

    authors: Baker JF,Perlmutter SI,Peterson BW,Rude SA,Robinson FR

    更新日期:1987-01-01 00:00:00

  • Models of behaviors when detecting displacements of joints.

    abstract::This report describes two models of human behavior when detecting displacements of joints that allow one to compare and integrate findings from different proprioception tests in a quantitative way. Results from various tests have led to different and often conflicting conclusions about proprioceptive behaviors and the...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00227954

    authors: Clark FJ,Deffenbacher KA

    更新日期:1996-12-01 00:00:00

  • Anticipatory Postural Adjustments associated with reaching movements are programmed according to the availability of visual information.

    abstract::During goal-directed arm movements, the eyes, head, and arm are coordinated to look at and reach the target. We examined whether the expectancy of visual information about the target modifies Anticipatory Postural Adjustments (APAs). Ten standing subjects had to (1) move the eyes, head and arm, so as to reach, with bo...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-017-4898-3

    authors: Esposti R,Bruttini C,Bolzoni F,Cavallari P

    更新日期:2017-05-01 00:00:00

  • Conceptual unifying constraints override sensorimotor interference during anticipatory control of bimanual actions.

    abstract::Traditional approaches to research on bimanual coordination focus on sensorimotor interference, motor programming, and effects of perception and feedback guidance; surprisingly, little is known about high-level conceptual constraints that might unify separate movements into coordinated actions. We investigated two pos...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-010-2365-5

    authors: Franz EA,McCormick R

    更新日期:2010-08-01 00:00:00

  • On the skilled plantar flexor motor action and unique electromyographic activity of ballet dancers.

    abstract::The study aimed to compare the ability of dance and non-dance subjects to perform fine control of a simple heel-raising/lowering movement, and to determine if there are any differences in motor unit activity in the primary plantar flexor muscles during the movement. Subjects were instructed to accurately track a sinus...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-017-5131-0

    authors: Saito S,Obata H,Kuno-Mizumura M,Nakazawa K

    更新日期:2018-02-01 00:00:00

  • Distribution of the calcium-binding proteins calbindin D-28K and parvalbumin in the superior colliculus of adult and neonatal cat and rhesus monkey.

    abstract::The distribution of the calcium-binding proteins calbindin D-28K and parvalbumin was examined in newborn and adult superior colliculus of cat and rhesus monkey using immunohistochemical techniques. In adult animals of both species, calbindin-immunoreactive neurons had a three-tiered arrangement: one band was present i...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-001-0908-5

    authors: McHaffie JG,Anstrom KK,Gabriele ML,Stein BE

    更新日期:2001-12-01 00:00:00

  • Reduced motor preparation during dual-task performance: evidence from startle.

    abstract::Previous studies have used a secondary probe reaction time (RT) task to assess attentional demands of a primary task. The current study used a startling acoustic stimulus (SAS) in a probe RT paradigm to test the hypothesis that attentional resources would be directly related to limitations in response preparation. Par...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-015-4340-7

    authors: Maslovat D,Drummond NM,Carter MJ,Carlsen AN

    更新日期:2015-09-01 00:00:00

  • The placing reaction in the standing cat: a model for the study of posture and movement.

    abstract::By measuring the forces applied by each limb supporting the weight of the standing quadruped (cat), before and during elicitation of the placing reaction, it was possible to examine quantitatively and qualitatively the postural events which preceded and accompanied forelimb displacement. The findings are summarized as...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00237713

    authors: Coulmance M,Gahéry Y,Massion J,Swett JE

    更新日期:1979-10-01 00:00:00

  • A global effect of capture saccades.

    abstract::When two target elements are presented in close proximity, the endpoint of a saccade is generally positioned at an intermediate location ('global effect'). Here, we investigated whether the global effect also occurs for eye movements executed to distracting elements. To this end, we adapted the oculomotor capture para...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-011-2602-6

    authors: Van der Stigchel S,de Vries JP,Bethlehem R,Theeuwes J

    更新日期:2011-04-01 00:00:00

  • Mono- and disynaptic excitatory inputs from the superior colliculus to vertical saccade-related neurons in the cat Forel's field H.

    abstract::Excitatory inputs to neurons in the Forel's field H (FFH) related to visually induced vertical saccades from the ipsilateral superior colliculus (SC) were investigated in chronically prepared alert cats. By stimulation of the deep or intermediate layer of the SC, upward augmenting neurons (ANs) and one long-lead downw...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00230857

    authors: Nakao S,Shiraishi Y,Li WB,Oikawa T

    更新日期:1990-01-01 00:00:00

  • Differential working memory correlates for implicit sequence performance in young and older adults.

    abstract::Our recent work has revealed that visuospatial working memory (VSWM) relates to the rate of explicit motor sequence learning (Bo and Seidler in J Neurophysiol 101:3116-3125, 2009) and implicit sequence performance (Bo et al. in Exp Brain Res 214:73-81, 2011a) in young adults (YA). Although aging has a detrimental impa...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-012-3189-2

    authors: Bo J,Jennett S,Seidler RD

    更新日期:2012-09-01 00:00:00

  • Do component motions recombine into a moving plaid percept?

    abstract::Two superimposed gratings, which differ in orientation and move independently, combine into a coherently moving plaid if the component gratings are similar. The effect on the plaid motion percept of the addition of texture to each grating was investigated. The texture disambiguates the motion of each component grating...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00228400

    authors: van den Berg AV,van de Grind WA

    更新日期:1993-01-01 00:00:00

  • Effects of eye position on saccadic eye movements and on the neuronal responses to auditory and visual stimuli in cat superior colliculus.

    abstract::Many neurons in the deeper layers of the superior colliculus (SC) respond to multiple sensory inputs--visual, auditory, and somatic--as well as provide signals essential for saccadic eye movements to targets in different modalities. When the eyes and pinnae are in primary position, the neural map of auditory space is ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00231709

    authors: Peck CK,Baro JA,Warder SM

    更新日期:1995-01-01 00:00:00

  • Low-frequency galvanic vestibular stimulation evokes two peaks of modulation in skin sympathetic nerve activity.

    abstract::We have previously shown that sinusoidal galvanic vestibular stimulation (sGVS), delivered bilaterally at 0.2-2.0 Hz, evokes a potent entrainment of sympathetic outflow to muscle and skin. Most recently, we showed that stimulation at 0.08-0.18 Hz generates two bursts of modulation of muscle sympathetic nerve activity ...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-012-3090-z

    authors: Hammam E,Dawood T,Macefield VG

    更新日期:2012-06-01 00:00:00

  • Understanding the contribution of binocular vision to the control of adaptive locomotion.

    abstract::Abstract. Although the contribution of binocular vision to reach-to-grasp movements has been extensively studied, it has been largely ignored in locomotion. The aim of these studies was to explore the role of binocular vision during the approach phase and step over the obstacle and the contribution of head movements t...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-001-0948-x

    authors: Patla AE,Niechwiej E,Racco V,Goodale MA

    更新日期:2002-02-01 00:00:00

  • Inverting the planning gradient: adjustment of grasps to late segments of multi-step object manipulations.

    abstract::When someone grasps an object, the grasp depends on the intended object manipulation and usually facilitates it. If several object manipulation steps are planned, the first step has been reported to primarily determine the grasp selection. We address whether the grasp can be aligned to the second step, if the second s...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-017-4892-9

    authors: Mathew H,Kunde W,Herbort O

    更新日期:2017-05-01 00:00:00

  • Comparing limb proprioception and oculomotor signals during hand-guided saccades.

    abstract::We previously showed that saccades tend to overshoot briefly flashed targets that were manually displaced in the dark (Ren et al. 2006). However it was not clear if the overshoot originated from a sensory error in measuring hand displacement or from a premotor error in saccade programming, because gaze and hand positi...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-007-0981-5

    authors: Ren L,Blohm G,Crawford JD

    更新日期:2007-09-01 00:00:00

  • Suppression of visually evoked postural responses.

    abstract::Normal subjects standing on an earth-fixed force platform inside a movable room displaced at velocities comparable to those accompanying spontaneous body sway, exhibit a visually evoked postural response (VEPR) some 600 ms after the start of the room movement. It consists of a displacement of the centre of force of th...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/BF00237488

    authors: Bronstein AM

    更新日期:1986-01-01 00:00:00

  • Pattern of cortical reorganization in amyotrophic lateral sclerosis: a functional magnetic resonance imaging study.

    abstract::Depending on individual lesion location and extent, reorganization of the human motor system has been observed with a high interindividual variability. In addition, variability of forces exerted, of motor effort, and of movement strategies complicates the interpretation of functional imaging studies. We hypothesize th...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-001-0981-9

    authors: Konrad C,Henningsen H,Bremer J,Mock B,Deppe M,Buchinger C,Turski P,Knecht S,Brooks B

    更新日期:2002-03-01 00:00:00

  • Chemical characterization of newly generated neurons in the striatum of adult primates.

    abstract::We recently demonstrated the existence of neurogenesis in the striatum of adult monkeys, but the number of striatal neurons generated under normal conditions was too small to establish their chemical phenotype. We therefore used brain-derived neurotrophic factor (BDNF), which promotes neuronal differentiation and surv...

    journal_title:Experimental brain research

    pub_type: 杂志文章

    doi:10.1007/s00221-005-0233-5

    authors: Bédard A,Gravel C,Parent A

    更新日期:2006-04-01 00:00:00