Abstract:
:The enkephalins Met-enkephalin and Leu-enkephalin were first isolated from porcine brain by Hughes and co-workers. We have recently isolated from bovine adrenals another enkephalin with the structure Tyr-Gly-Gly-Phe-Met-Arg-Phe, or Met-enkephalin-Arg6-Phe7 (ref. 2). We report here that this new heptapeptide is found in human, rat and bovine striatum in concentrations comparable with or greater than that of Leu-enkephalin. This molecule should not be considered as a mere precursor of Met-enkephalin. A pharmacological study indicates that this naturally occurring enkephalin has similar properties to the two enkephalins characterized earlier.
journal_name
Naturejournal_title
Natureauthors
Rossier J,Audigier Y,Ling N,Cros J,Udenfriend Sdoi
10.1038/288088a0subject
Has Abstractpub_date
1980-11-06 00:00:00pages
88-90issue
5786eissn
0028-0836issn
1476-4687journal_volume
288pub_type
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