Perturbation of the switch-on of transcriptase activity in intermediate subviral particles from reovirus.

abstract：:Lung diseases are major cause of morbidity and mortality worldwide. The progress in regenerative medicine and stem cell research in the lung are currently a fast-growing research topic that can provide solutions to these major health problems. Under normal conditions, the rate of cellular proliferation is relatively l...

journal_title：Journal of cellular physiology

authors： Zhu Y,Chen X,Yang X,El-Hashash A

更新日期：2018-10-01 00:00:00

abstract：:Two important mediators of endothelium-dependent regulation of vascular smooth muscle tone and proliferation are nitric oxide (NO) and endothelin (ET-1). An imbalance between NO and ET-1 may contribute to the alterations in vascular tone characteristic of cardiovascular disease. The objective of this study was to dete...

journal_title：Journal of cellular physiology

authors： Redmond EM,Cahill PA,Hodges R,Zhang S,Sitzmann JV

更新日期：1996-03-01 00:00:00

abstract：:Nerve growth factor (NGF) is required for the growth and development of sensory and sympathetic neurons. Incubation of chick dorsal root ganglionic cells without NGF resulted in a decrease of active (Na+,K+-pump-mediated) K+ influx over a period of several hours. Addition of NGF to NGF-deprived cells caused 1) a retur...

journal_title：Journal of cellular physiology

authors： Boonstra J,Skaper SD,Varon S

更新日期：1982-10-01 00:00:00

abstract：:Hydatid cyst, the larval stage of the tapeworm Echinococcus granulosus and a causative agent of cystic echinococcosis, possesses a vast number of antigenic peptides that are constantly presented in the host immune system during infection. Here, we sought to provide more information about the cellular/humoral component...

journal_title：Journal of cellular physiology

authors： Vatankhah A,Ghaffari SMR,Vatankhah RG,Piurkó V,Tímár J,Avan A,Jazayeri MH

更新日期：2019-03-01 00:00:00

abstract：:Helicobacter pylori lives in the stomach lumen adhering and specifically interacting with gastric epithelial cells. H. pylori infection can cause a broad range of diseases. Although most infected individuals only develop a chronic inflammation of the stomach, some patients progress to chronic gastritis, duodenal ulcer...

journal_title：Journal of cellular physiology

authors： De Luca A,De Falco M,Iaquinto S,Iaquinto G

更新日期：2004-09-01 00:00:00

abstract：:Intervertebral disc degeneration and associated back pain are relatively common but sparsely understood conditions, affecting over 70% of the population during some point of life. Disc degeneration is often associated with a loss of nucleus pulposus (NP) cells. Genetic mouse models offer convenient avenues to understa...

journal_title：Journal of cellular physiology

authors： Mohanty S,Pinelli R,Dahia CL

更新日期：2020-01-01 00:00:00

abstract：:Osteoblasts are the main functional cells of bone formation, and they are responsible for the synthesis, secretion, and mineralization of the bone matrix. Phosphatidylinositol-3-kinase/Akt is an important signaling pathway involved in the regulation of cell proliferation, death, and survival. Some studies have shown t...

journal_title：Journal of cellular physiology

authors： Bai Y,Zhang Q,Chen Q,Zhou Q,Zhang Y,Shi Z,Nong H,Liu M,Zeng G,Zong S

更新日期：2020-12-30 00:00:00

abstract：:Lung cancer is a main cause of death all over the world with a high incidence rate. Metastasis into neighboring and distant tissues as well as resistance of cancer cells to chemotherapy demand novel strategies in lung cancer therapy. Curcumin is a naturally occurring nutraceutical compound derived from Curcuma longa (...

journal_title：Journal of cellular physiology

authors： Ashrafizadeh M,Najafi M,Makvandi P,Zarrabi A,Farkhondeh T,Samarghandian S

更新日期：2020-12-01 00:00:00

abstract：:The roles of Sonic hedgehog (Shh) and Bone morphogenetic protein-2 (Bmp-2) in osteoblast differentiation were investigated using in vitro cell systems. Recombinant amino-terminal portion of SHH (rSHH-N) dose dependently stimulated ALP activity in C3H10T1/2 and MC3T3-E1 cells. rSHH-N induced expression of Osteocalcin m...

journal_title：Journal of cellular physiology

authors： Yuasa T,Kataoka H,Kinto N,Iwamoto M,Enomoto-Iwamoto M,Iemura S,Ueno N,Shibata Y,Kurosawa H,Yamaguchi A

更新日期：2002-11-01 00:00:00

abstract：:NIH-3T3 cells transformed by the EJ-ras oncogene display reduced platelet-derived growth factor (PDGF)-stimulated phospholipase C activity as measured by inositol 1,4,5-triphosphate (IP3) synthesis and Ca2+ mobilization. The lack of PDGF-stimulated Ca2+ mobilization in EJ-ras transformed cells is not due to a loss of ...

journal_title：Journal of cellular physiology

authors： Olinger PL,Benjamin CW,Gorman RR,Connor JA

更新日期：1989-05-01 00:00:00

abstract：:Staurosporine, a microbial-derived protein kinase inhibitor, reversibly blocked non-synchronized, replicating cultures of the human lung epithelial cell line EKVX in the G1 phase of cell cycle and inhibited DNA synthesis and cell replication. The mechanism of this cell-cycle arrest in EKVX cells by staurosporine was l...

journal_title：Journal of cellular physiology

authors： Lin Y,Chrest FJ,Gabrielson EW

更新日期：1992-09-01 00:00:00

abstract：:Shear stress changes are associated with a repertory of signaling cascade modulating vascular phenotype. As shear stress-related tensional forces might be associated with pathophysiological susceptibility, a more comprehensive molecular map needs to be addressed. Thus, we subjected human umbilical vein endothelial cel...

journal_title：Journal of cellular physiology

authors： Pinto TS,Fernandes CJDC,da Silva RA,Gomes AM,Vieira JCS,Padilha PM,Zambuzzi WF

更新日期：2019-07-01 00:00:00

abstract：:Dental pulp stem cells (DPSCs) are clonogenic, self-renewing, and multi-potential DPSCs capable of differentiating into osteoblasts. In this study, primary cell cultures were obtained from human dental pulp tissue of developing third molars, and flow cytometry was used to sort the subpopulation of DPSCs with STRO-1 an...

journal_title：Journal of cellular physiology

authors： Huang CH,Tseng WY,Yao CC,Jeng JH,Young TH,Chen YJ

更新日期：2010-10-01 00:00:00

abstract：:Bcl-2 associated athanogene 5 (Bag5) is a novel endoplasmic reticulum (ER) regulator. However, its role in catecholamine-induced endothelial cells damage has not been fully understood. In our study, catecholamine was used to mimic hypertension-related endothelial cell damage. Then, western blots, enzyme-linked immunos...

journal_title：Journal of cellular physiology

authors： Zhu H,Zhao M,Chen Y,Li D

更新日期：2021-02-01 00:00:00

abstract：:Long noncoding RNAs have been reported to be important regulators in numerous cancers. In this study, we found that HOXC13 antisense RNA (HOXC13-AS) was highly expressed in head and neck squamous carcinoma (HNSC) tissues in The Cancer Genome Atlas database. Nasopharyngeal carcinoma (NPC) belongs to HNSC. Therefore, we...

journal_title：Journal of cellular physiology

authors： Gao C,Lu W,Lou W,Wang L,Xu Q

更新日期：2019-08-01 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) promotes the regeneration of periodontal tissue. Since angiogenesis is important for tissue regeneration, investigating effect of BDNF on endothelial cell function may help to reveal its mechanism, whereby, BDNF promotes periodontal tissue regeneration. In this study, we examin...

journal_title：Journal of cellular physiology

authors： Matsuda S,Fujita T,Kajiya M,Takeda K,Shiba H,Kawaguchi H,Kurihara H

更新日期：2012-05-01 00:00:00

abstract：:Osteoblasts are terminally differentiated cells with mesenchymal origins, known to possess pivotal roles in sustaining bone microstructure and homeostasis. These cells are implicated in the pathophysiology of various bone disorders, especially osteoporosis. Over the last few decades, strategies to impede bone resorpti...

journal_title：Journal of cellular physiology

authors： Aslani S,Abhari A,Sakhinia E,Sanajou D,Rajabi H,Rahimzadeh S

更新日期：2019-06-01 00:00:00

abstract：:Primary astroglial cultures were used to compare the relationships to cell cycling of dolichol-linked glycoprotein synthesis, and of availability of mevalonate, the precursor of dolichol and other isoprenoid lipids. With shift-up to 10% serum (time 0) after 48 h of serum depletion, the proportion of cells in S phase (...

journal_title：Journal of cellular physiology

authors： Langan TJ,Slater MC

更新日期：1991-11-01 00:00:00

abstract：:The snRNAs are abundant and stable components of the interphase nucleus. Aqueous and non-aqueous cell fractionation demonstrate that the snRNAs appear transiently in the cytoplasm shortly after transcription, before returning permanently to the interphase nucleus. In pulse label and chase experiments, the newly synthe...

journal_title：Journal of cellular physiology

authors： Zieve GW

更新日期：1987-05-01 00:00:00

abstract：:Five-week-old female mice supplemented with estradiol and progesterone are able to respond to epidermal growth factor (EGF) and EGF-like growth factors (alpha-transforming growth factor [alpha-TGF] and crude mammary-derived growth factor) with local lobuloalveolar development when these growth factors are directly int...

journal_title：Journal of cellular physiology

authors： Vonderhaar BK

更新日期：1987-09-01 00:00:00

abstract：:Pyroptosis, a type of programmed cell death mediated by gasdermin, is characterized by the swelling and rupture of cells, release of cellular contents and a strong inflammatory response, which is critical for controlling microbial infection. Pattern recognition receptors recognize the intracellular and extracellular p...

journal_title：Journal of cellular physiology

authors： Xia X,Wang X,Zheng Y,Jiang J,Hu J

更新日期：2019-06-01 00:00:00

abstract：:Peripheral nerve physiology and regeneration has been observed and investigated in literature but surgical applications to reconstruct and restore motor or sensory functions are still in a developmental phase. The peripheral nerve progresses slowly and incompletely compared with other tissues, it may provoke separatio...

journal_title：Journal of cellular physiology

authors： Riccio M,Marchesini A,Pugliese P,De Francesco F

更新日期：2019-04-01 00:00:00

abstract：:Dietary fiber has been suggested to suppress colorectal cancer development, although the mechanisms contributing to this beneficial effect remain elusive. Butyrate, a fermentation product of fiber, has been shown to have anti-proliferative and pro-apoptotic effects on colorectal cancer cells. The metabolic fate of but...

journal_title：Journal of cellular physiology

authors： Han A,Bennett N,MacDonald A,Johnstone M,Whelan J,Donohoe DR

更新日期：2016-08-01 00:00:00

abstract：:Mammalian sperm require to spend a limited period of time in the female reproductive tract to become competent to fertilize in a process called capacitation. It is well established that HCO3- is essential for capacitation because it activates the atypical soluble adenylate cyclase ADCY10 leading to cAMP production, an...

journal_title：Journal of cellular physiology

authors： Puga Molina LC,Pinto NA,Torres Rodríguez P,Romarowski A,Vicens Sanchez A,Visconti PE,Darszon A,Treviño CL,Buffone MG

更新日期：2017-06-01 00:00:00

abstract：:The presence of inflammatory cells and their products in the tumor microenvironment plays a crucial role in the pathogenesis of a tumor. Releasing the cytokines from a host in response to infection and inflammation can inhibit tumor growth and progression. However, tumor cells can also respond to the host cytokines wi...

journal_title：Journal of cellular physiology

authors： Shadpour P,Zamani M,Aghaalikhani N,Rashtchizadeh N

更新日期：2019-02-18 00:00:00

abstract：:Our study examines the effect of apoptosis on prothymosin alpha, an abundant, nuclear protein intimately involved with proliferation of all mammalian cells. When HeLa cells were treated with actinomycin D, with etoposide, or with staurosporine following synchronization with hydroxyurea, they underwent apoptosis based ...

journal_title：Journal of cellular physiology

authors： Enkemann SA,Wang RH,Trumbore MW,Berger SL

更新日期：2000-02-01 00:00:00

abstract：:The highly conserved homeodomains and HMG domains are components of a large number of proteins that play a role in the transcriptional regulation of gene expression during embryogenesis. Both the HMG domain and the homeodomain serve as interfaces for factor interactions with DNA, as well as with other proteins, and it...

journal_title：Journal of cellular physiology

authors： Dailey L,Basilico C

更新日期：2001-03-01 00:00:00

abstract：:Optical indicators of the cationic, cyanine and anionic oxonol classes were used to evaluate the plasma membrane potential of animal cells in suspension and in monolayer culture. The optical signals were calibrated by using diffusion potentials either of K+ (in the presence of valinomycin) or of H+ (in the presence of...

journal_title：Journal of cellular physiology

authors： Bashford CL,Alder GM,Gray MA,Micklem KJ,Taylor CC,Turek PJ,Pasternak CA

更新日期：1985-06-01 00:00:00

abstract：:Although the type 1 insulin-like growth factor receptor (IGF-IR) is a potent inhibitor of apoptosis, its C-terminus sequence sends contradictory signals, including a clearly proapoptotic signal. We have synthesized a peptide, peptide 2, having the sequence of the IGF-IR from residue 1282 to residue 1298 (C-terminus of...

journal_title：Journal of cellular physiology

authors： Reiss K,Yumet G,Shan S,Huang Z,Alnemri E,Srinivasula SM,Wang JY,Morrione A,Baserga R

更新日期：1999-10-01 00:00:00

abstract：:The p21 activated kinases (Paks), an evolutionarily conserved family of serine/threonine kinases, are important for a variety of cellular functions including cell morphogenesis, motility, survival, mitosis, and angiogenesis. Paks are widely expressed in numerous tissues and are activated by growth factors and extracel...

journal_title：Journal of cellular physiology

authors： Kumar R,Vadlamudi RK

更新日期：2002-11-01 00:00:00