Cytoplasmic maturation of the snRNAs.

abstract：:Cell culture conditions can vary between laboratories and have been optimised for 2D cell culture. In this study, engineered muscle was cultured in 5.5 mM low glucose (LG) or 25 mM high glucose (HG) and in the absence or presence (+S) of streptomycin and the effect on C2C12 tissue-engineered muscle function and metabo...

journal_title：Journal of cellular physiology

authors： Khodabukus A,Baar K

更新日期：2015-06-01 00:00:00

abstract：:Epithelial Cell Adhesion Molecule (EpCAM), or CD326, is a trans-membrane glycoprotein expressed by multiple normal epithelia as well as carcinoma. Human hepatic stem cells and bile duct epithelium of the liver are EpCAM positive. In tumor cell lines, its intracellular domain can be released after cleavage of the extra...

journal_title：Journal of cellular physiology

authors： Gerlach JC,Foka HG,Thompson RL,Gridelli B,Schmelzer E

更新日期：2018-06-01 00:00:00

abstract：:The present study uses the osteoclast precursor clonal line, HD-11EM, to study the potential of hydrogen peroxide (H2O2) in mediating the differentiation of HD-11EM into osteoclast-like cells. HD-11EM cells are a newly established clonal cell line that, in response to 1alpha,25-(OH)2D3, differentiate into osteoclast-l...

journal_title：Journal of cellular physiology

authors： Steinbeck MJ,Kim JK,Trudeau MJ,Hauschka PV,Karnovsky MJ

更新日期：1998-09-01 00:00:00

abstract：:Members of the transforming growth factor-β (TGF-β) family of cytokines are involved in diverse physiological processes. Although TGF-β is known to play multiple roles in the mammalian central nervous system (CNS), its role in neuronal development has not been explored. We have studied the effects of TGF-β1 on the ele...

journal_title：Journal of cellular physiology

authors： Zhuang JL,Wang CY,Zhou MH,Duan KZ,Mei YA

更新日期：2012-01-01 00:00:00

abstract：:The increased levels of c-Myc protein observed previously in an ovarian carcinoma cell line stably transfected to express HER2 has suggested a role for the HER2 pathway in c-Myc expression. Analysis of HER2-transfected cells stimulated with heregulin beta1 (HRG) revealed increased c-Myc protein levels but not a corres...

journal_title：Journal of cellular physiology

authors： Galmozzi E,Casalini P,Iorio MV,Casati B,Olgiati C,Ménard S

更新日期：2004-07-01 00:00:00

abstract：:Syndecans are constitutively shed from growing epithelial cells as the part of normal cell surface turnover. However, increased serum levels of the soluble syndecan ectodomain have been reported to occur during bacterial infections. The aim of this study was to evaluate the potential of lipopolysaccharide (LPS) from t...

journal_title：Journal of cellular physiology

authors： Andrian E,Grenier D,Rouabhia M

更新日期：2005-07-01 00:00:00

abstract：:In this present study, Oreochromis mossambicus tilapia were transferred to cold water at 12°C for various time intervals (1, 4, 8, 24, and 48 hr) and its innate immune response was analyzed by studying cellular and humoral parameters. In vivo, alternative complement pathway activity in blood plasma was rapidly increas...

journal_title：Journal of cellular physiology

authors： Velmurugan BK,Chan CR,Weng CF

更新日期：2019-02-11 00:00:00

abstract：:The extracellular matrix (ECM) is a dynamic component of tissue architecture that physically supports cells and actively influences their behavior. In the context of bone regeneration, cell-secreted ECMs have become of interest as they reproduce tissue-architecture and modulate the promising properties of mesenchymal ...

journal_title：Journal of cellular physiology

authors： Baroncelli M,van der Eerden BC,Kan YY,Alves RD,Demmers JA,van de Peppel J,van Leeuwen JP

更新日期：2018-01-01 00:00:00

abstract：:Connective Tissue Growth Factor (CCN2/CTGF) and Nephroblastoma Overexpressed (CCN3/NOV) execute key functions within the hematopoietic compartment. Both are abundant in the bone marrow stroma, which is a niche for hematopoiesis and supports marrow function. Roles for 1,25-dihydroxyvitamin D3 (calcitriol) and all-trans...

journal_title：Journal of cellular physiology

authors： Piszczatowski RT,Rafferty BJ,Rozado A,Parziale JV,Lents NH

更新日期：2015-11-01 00:00:00

abstract：:The tumor suppressor p53-related p73 shares significant amino-acid sequence identity with p53. Like p53, p73 recognizes canonical p53 DNA-binding sites and activates p53-responsive target genes and induces apoptosis. Moreover, SIRT1 binds to p53 while repressing the expression of their target genes. Here, we report th...

journal_title：Journal of cellular physiology

authors： Dai JM,Wang ZY,Sun DC,Lin RX,Wang SQ

更新日期：2007-01-01 00:00:00

abstract：:Glutamine (gln) is the most abundant free amino acid in the blood. It is involved in important metabolic and biochemical processes, like cell proliferation and oxidative stress. Previous studies have demonstrated that gln concentration in human plasma decreases in several conditions such as sepsis, ischemia-reperfusio...

journal_title：Journal of cellular physiology

authors： Viggiano E,Passavanti MB,Pace MC,Sansone P,Spaziano G,Viggiano A,Aurilio C,Monda M,Viggiano A,Pota V,De Luca B,De Luca E

更新日期：2012-05-01 00:00:00

abstract：:Cigarettes contain various chemicals with the potential to influence metabolic health. Exposure to cigarette smoke causes a dysfunction in pancreatic β-cells and impairs insulin production. However, the mechanisms for cigarette smoke-induced reduction of insulin remain largely unclear. Data from 558 patients with diab...

journal_title：Journal of cellular physiology

authors： Sun Q,Xu H,Xue J,Yang Q,Chen C,Yang P,Han A,Tu Q,Lu J,Gao X,Xiang Q,Liu Q

更新日期：2018-11-01 00:00:00

abstract：:We have characterized the physiological and biochemical properties of the Na(+)/K(+) pump and its molecular expression in L8 rat muscle cells. Pump properties were measured by [(3)H]ouabain binding and (86)Rb uptake. Scatchard plot analysis of specific ouabain binding indicated the presence of a single family of bindi...

journal_title：Journal of cellular physiology

authors： Sharabani-Yosef O,Bak A,Nir U,Sampson SR

更新日期：2001-06-01 00:00:00

abstract：:Phosphodiesterase 5A (PDE5A) specifically degrades the ubiquitous second messenger cGMP and experimental and clinical data highlight its important role in cardiac diseases. To address PDE5A role in cardiac physiology, three splice variants of the PDE5A were cloned for the first time from mouse cDNA library (mPde5a1, m...

journal_title：Journal of cellular physiology

authors： Campolo F,Zevini A,Cardarelli S,Monaco L,Barbagallo F,Pellegrini M,Cornacchione M,Di Grazia A,De Arcangelis V,Gianfrilli D,Giorgi M,Lenzi A,Isidori AM,Naro F

更新日期：2018-01-01 00:00:00

abstract：:In vitro bioluminescence components of the dinoflagellates Gonyaulax polyedra, G. tamarensis, Dissodinium lunual, and Pyrocystis noctiluca were studied. The luciferases and luciferins of the four species cross-react in all combinations. All of these species possess high-molecular weight luciferases (200,000-400,000 da...

journal_title：Journal of cellular physiology

authors： Schmitter RE,Njus D,Sulzman FM,Gooch VD,Hastings JW

更新日期：1976-01-01 00:00:00

abstract：:Lesional psoriatic epidermis displays a number of phenotypic changes that are distinct from the differentiation program found in normal interfollicular epidermis. In psoriatic epidermis, keratinocytes are hyperproliferative and several differentiation-associated molecules are expressed that are absent in normal skin (...

journal_title：Journal of cellular physiology

authors： Van Ruissen F,de Jongh GJ,Zeeuwen PL,Van Erp PE,Madsen P,Schalkwijk J

更新日期：1996-08-01 00:00:00

abstract：:Trypsinized normal rat embryo fibroblasts and untrypsinized and trypsinized transformed rat fibroblasts have two orders of binding sites for bacterial glycolipid mR595. The high order sites fix 1--3 micrograms glycolipid mR595/10(5) cells and those of the low order fix about 6 microgram glycolipids mR595/10(6) cells. ...

journal_title：Journal of cellular physiology

authors： Lallier R,Trudel M,Brailovsky CA,Nigam VN

更新日期：1979-01-01 00:00:00

abstract：:The export of rRNP particles from nuclei isolated from Tetrahymena was investigated after preincubating the nuclei at different temperatures under nonpermissive export-conditions. We observed a new phenomenon: Temperature elevation from the sublethal cells' growth temperature, 8 degrees C, to the optimal temperature, ...

journal_title：Journal of cellular physiology

authors： Wunderlich F,Giese G,Herlan G

更新日期：1984-08-01 00:00:00

abstract：:Much research has been conducted to discover novel techniques to reverse the process of tumorigenesis and, cure already stablished malignancies. One well-stablished approach has been the use of organic compounds and naturally found agents such as melatonin whose anticancer effects have been shown in multiple studies, ...

journal_title：Journal of cellular physiology

authors： Mirza-Aghazadeh-Attari M,Mohammadzadeh A,Adib A,Darband SG,Sadighparvar S,Mihanfar A,Majidinia M,Yousefi B

更新日期：2019-08-01 00:00:00

abstract：:The expression profile and functions of the brain-enriched Rab22B/Rab31 small GTPase had remained uncharacterized. Using specific antibodies against Rab22B, we found the protein to be exceptionally enriched in nestin and RC2-positive radial glia of the embryonic mouse brain. In the adult brain, Rab22B is rather specif...

journal_title：Journal of cellular physiology

authors： Ng EL,Ng JJ,Liang F,Tang BL

更新日期：2009-12-01 00:00:00

abstract：:Highly purified human blood burst-forming units-erythroid (BFU-E) were used to study the effects of interferon gamma (IFN gamma). IFN gamma inhibited erythroid colony formation, cell proliferation, and differentiation of day 3 to day 6 mature BFU-E in a dose-dependent manner. The primitive BFU-E (day 1 and day 2 cells...

journal_title：Journal of cellular physiology

authors： Dai CH,Krantz SB,Kollar K,Price JO

更新日期：1995-11-01 00:00:00

abstract：:Integrin α2β1 plays an important role in cellular migration and metastasis processes associated with prostate cancer. The aim of this study was to assess whether selective inhibition of integrin α2β1 is an effective strategy to target metastatic prostate cancer cells. In this regard, we examined the effects of the inh...

journal_title：Journal of cellular physiology

authors： Salemi Z,Azizi R,Fallahian F,Aghaei M

更新日期：2020-12-10 00:00:00

abstract：:HeLa (substrain Ho) grown in serum free medium showed an increase in the specific activity of alkaline phosphatase when fetal calf serum (10%) was added to the medium (9.7 nmoles/sec/mg protein to 86.8). Under the same conditions, eight intracellular enzymes showed no increase in activity. Similar results were obtaine...

journal_title：Journal of cellular physiology

authors： Carlson CW

更新日期：1979-01-01 00:00:00

abstract：:We studied the clinicopathological significance for Calreticulin (CRT) expression in pancreatic cancer (PC), and its functional relationship with other signaling genes (especially with p53) in regulating the biological behavior of PC cells. IHC, IF, IB, and real-time PCR were used to detect CRT expression in PC, while...

journal_title：Journal of cellular physiology

authors： Sheng W,Chen C,Dong M,Zhou J,Liu Q,Dong Q,Li F

更新日期：2014-07-01 00:00:00

abstract：:The predominant cyclooxygenase products of keratinocytes are prostaglandin (PG)E2 and PGF2 alpha with only trace amounts of PGI2 synthesis detected. When normal or immortal (NM1) keratinocytes were co-cultured with mitomycin C-treated 3T3 cells, increased synthesis of PGI2 was noted compared to mitomycin C-treated 3T3...

journal_title：Journal of cellular physiology

authors： Baden HP,Goldaber ML,Kvedar JC

更新日期：1992-02-01 00:00:00

abstract：:Nowadays, epigenetics covers a crucial role in different fields of science. The enhancer of zeste homolog 2 (EZH2), the catalytic subunit of the Polycomb Repressive Complex 2 (PRC2), is a big proponent of how epigenetic changes can affect the initiation and progression of several diseases. Through its catalytic activi...

journal_title：Journal of cellular physiology

authors： Sanna L,Marchesi I,Melone MAB,Bagella L

更新日期：2018-09-01 00:00:00

abstract：:Autophagy is a crucial cellular homeostatic process and an important part of the host defense system. Dysfunction in autophagy enhances tissue susceptibility to infection and multiple diseases. However, the role of nucleotide oligomerization domain 1 (NOD1) in autophagy in bovine hepatocytes is not well known. Therefo...

journal_title：Journal of cellular physiology

authors： Roy AC,Chang G,Roy S,Ma N,Gao Q,Shen X

更新日期：2020-12-24 00:00:00

abstract：:Rous sarcoma virus (RSV)-infected chicken embryo cells were used to study the effect of viral transformation on the hormone-stimulated synthesis of cyclic AMP. Transformation by RSV greatly increased the cells' ability to synthesize and accumulate cyclic AMP in response to the beta-adrenergic agonist isoproterenol as ...

journal_title：Journal of cellular physiology

authors： Howard RF,Friis RR,Sheppard JR,Glossmann H

更新日期：1982-06-01 00:00:00

abstract：:Infection with Verotoxin producing Escherichia coli (VTEC) has been implicated in hemolytic uremic syndrome, the leading cause of pediatric renal failure. Verotoxin (VT) binds to globotriaosylceramide (Gal alpha 1-4Gal beta 1-4GlcCer Gb3) in susceptible cells. Gb3 is required for cytotoxicity and toxin-resistant cells...

journal_title：Journal of cellular physiology

authors： Pudymaitis A,Lingwood CA

更新日期：1992-03-01 00:00:00

abstract：:It has been shown that the insulin-like growth factor (IGF-I) gene is spliced in response to mechanical signals producing forms of IGF-I which have different actions. In order to study how mechanical signals influence this gene splicing in developing muscle, C2C12 cells were grown in three-dimensional (3D) culture and...

journal_title：Journal of cellular physiology

authors： Cheema U,Brown R,Mudera V,Yang SY,McGrouther G,Goldspink G

更新日期：2005-01-01 00:00:00