Localization of gastrinomas by transhepatic portal catheterization and gastrin assay.

abstract：BACKGROUND/AIMS:Ursodeoxycholic acid (UDCA) and colchicine have beneficial effects in primary biliary cirrhosis (PBC). The efficacy of colchicine and UDCA in PBC was compared in a 2-year placebo-controlled study (n = 90). METHODS:Clinical events, laboratory test results, and liver histology were recorded at the beginn...

journal_title：Gastroenterology

authors： Vuoristo M,Färkkilä M,Karvonen AL,Leino R,Lehtola J,Mäkinen J,Mattila J,Friman C,Seppälä K,Tuominen J

更新日期：1995-05-01 00:00:00

abstract：:To determine the pattern of inheritance of lactase deficiency, we studied 104 American Indian and 2 white subjects in 19 families. Subjects were considered deficient in lactase if breath-hydrogen excretion exceeded 0.20 ml per min above fasting at 2 hr after a lactose load of 2 g per kg of body weight (maximum 50 g). ...

journal_title：Gastroenterology

authors： Newcomer AD,Gordon H,Thomas PJ,McGill DB

更新日期：1977-11-01 00:00:00

abstract：DESCRIPTION:Thanks to ready access to hydrogen breath testing, small intestinal bacterial overgrowth (SIBO) is now commonly diagnosed among individuals presenting with a variety of gastrointestinal and even nongastrointestinal symptoms and is increasingly implicated in lay press and media in the causation of a diverse ...

journal_title：Gastroenterology

authors： Quigley EMM,Murray JA,Pimentel M

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND & AIMS:Major histocompatibility complex (MHC) class I-restricted CD8(+) T cells are required for clearance of hepatitis C virus (HCV) infection. MHC class I expression is up-regulated by type I and II interferons (IFNs). However, little is known about the effects of HCV infection on IFN-induced expression of...

journal_title：Gastroenterology

authors： Kang W,Sung PS,Park SH,Yoon S,Chang DY,Kim S,Han KH,Kim JK,Rehermann B,Chwae YJ,Shin EC

更新日期：2014-05-01 00:00:00

abstract：:The prevalence of gastroesophageal varices and gastrointestinal hemorrhage was determined in 124 patients with severe chronic active liver disease (CALD) receiving prednisone and followed regularly for up to 10 yr. Varices were demonstrated by contrast radiography in only 19 patients (15%). Ten had varices before ther...

journal_title：Gastroenterology

authors： Czaja AJ,Wolf AM,Summerskill WH

更新日期：1979-10-01 00:00:00

abstract：:Urokinase, the plasminogen activator from human urine, produces a dose-dependent increase in blood flow in the canine superior mesenteric artery when injected intraarterially at doses from 10(-1) to 10(3) units kg-1. This vasodilation persists despite blockade of beta-adrenergic and histamine H1 and H2 receptors as we...

journal_title：Gastroenterology

authors： Gurll N,Zinner MJ,Turtinen L,Reynolds DG

更新日期：1978-09-01 00:00:00

abstract：:The possible involvement of tumor necrosis factor-alpha in the pathogenesis of an experimentally induced hepatitis was investigated. Balb/c mice were primed with Propionibacterium acnes to induce the infiltration of mononuclear cells into the liver. Immunohistochemical study showed that most of the accumulated mononuc...

journal_title：Gastroenterology

authors： Nagakawa J,Hishinuma I,Hirota K,Miyamoto K,Yamanaka T,Tsukidate K,Katayama K,Yamatsu I

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND & AIMS:Alterations of hepatic cholesterol metabolism in patients with cholesterol gallstones are still controversial. This study investigated whether hepatic cholesterol metabolism is altered in Japanese patients with cholesterol gallstones. METHODS:In this systematic study of 24 middle-aged nonobese and no...

journal_title：Gastroenterology

authors： Ito T,Kawata S,Imai Y,Kakimoto H,Trzaskos JM,Matsuzawa Y

更新日期：1996-05-01 00:00:00

abstract：:The results of a clinical trial comparing slow-release 5-aminosalicylic acid tablets (Pentasa) and enteric-coated sulfasalazine tablets (Salazopyrin) with regard to the efficacy of maintaining ulcerative colitis patients in remission for 12 mo and with regard to safety of treatment are reported. Seventy-five patients ...

journal_title：Gastroenterology

authors： Mulder CJ,Tytgat GN,Weterman IT,Dekker W,Blok P,Schrijver M,van der Heide H

更新日期：1988-12-01 00:00:00

abstract：BACKGROUND & AIMS:Idiopathic inflammatory bowel disease (IBD) is associated with bone loss in more than 30% of cases. Nevertheless, the pathogenesis of the bone loss is uncertain. The aim of this study was to investigate the bone loss and underlying mechanisms using an animal model of IBD. METHODS:Severe colitis was i...

journal_title：Gastroenterology

authors： Lin CL,Moniz C,Chambers TJ,Chow JW

更新日期：1996-11-01 00:00:00

abstract：BACKGROUND & AIMS:Although different brands of fecal immunochemical tests (FITs) are used for colorectal cancer (CRC) screening, few studies have compared their accuracy in detecting advanced neoplasia. METHODS:We performed a large prospective cohort study within the Dutch national CRC screening program to evaluate 2 ...

journal_title：Gastroenterology

authors： Wieten E,de Klerk CM,van der Steen A,Ramakers CR,Kuipers EJ,Hansen BE,Lansdorp-Vogelaar I,Bossuyt PM,Dekker E,Spaander MCW

更新日期：2018-11-01 00:00:00

abstract：:The burden of disease consequent to hepatitis C virus (HCV) infection has been well described and is expected to increase dramatically over the next decade. Current approved antiviral therapies are effective in eradicating the virus in approximately 50% of infected patients. However, pegylated interferon and ribavirin...

journal_title：Gastroenterology

authors： Pawlotsky JM,Chevaliez S,McHutchison JG

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND & AIMS:People infected with human immunodeficiency virus (HIV) have an increased risk of some malignancies, but little is known about the effects of infection on risk of cancers of the upper gastrointestinal tract. We evaluated the risks of different histologic and anatomic subtypes of carcinomas and non-Hod...

journal_title：Gastroenterology

authors： Persson EC,Shiels MS,Dawsey SM,Bhatia K,Anderson LA,Engels EA

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND & AIMS:Deoxycholate (DC) has proapoptotic and tumorigenic effects in different cell types of the gastrointestinal tract. Exposure of BHK-21 (stromal) cells to DC induces Ca(2+) entry at the plasma membrane, which affects intracellular Ca(2+) signaling. We assessed whether DC-induced increases in [Ca(2+)] can...

journal_title：Gastroenterology

authors： Gerbino A,Ranieri M,Lupo S,Caroppo R,Debellis L,Maiellaro I,Caratozzolo MF,Lopez F,Colella M

更新日期：2009-09-01 00:00:00

abstract：:A patient who developed symptomatic giardiasis after a tour of the Soviet Union is presented. The diagnosis was established by duodenal aspiration. A small intestinal biopsy revealed total villous atrophy in the absence of celiac sprue or a gastrointestinal immunodeficiency syndrome, a finding not previously described...

journal_title：Gastroenterology

authors： Levinson JD,Nastro LJ

更新日期：1978-02-01 00:00:00

abstract：:There is considerable evidence that fluids are removed from the peritoneal cavity by drainage into lymphatics lining the surface of the diaphragm, but there is little quantitative information on the rate of reabsorption as affected by conditions which exist in cirrhotic ascites. In the present study a plethysmographic...

journal_title：Gastroenterology

authors： Zink J,Greenway CV

更新日期：1977-11-01 00:00:00

abstract：:Bile acids cause diarrhea by inducing colonic secretion, probably mediated through the cyclic AMP system. The aim was to determine the effects of an adenylate cyclase inhibitor, propranolol, on deoxycholic acid (DCA) stimulation of net secretion and the cyclic AMP system in the colon. In each of 30 New Zealand white r...

journal_title：Gastroenterology

authors： Conley D,Coyne M,Chung A,Bonorris G,Schoenfield L

更新日期：1976-07-01 00:00:00

abstract：:To study the peripheral effect of somatostatin in dogs a tiny Silastic catheter was implanted in an almost terminal branch of the mesenteric artery, providing blood supply to a jejunal segment of 5-10 cm. In 4 dogs one catheter was implanted, perfusing a small bowel segment about 60 cm below the angle of Treitz; in 3 ...

journal_title：Gastroenterology

authors： Hostein J,Janssens J,Vantrappen G,Peeters TL,Vandeweerd M,Leman G

更新日期：1984-11-01 00:00:00

abstract：:Three cases of Stevens-Johnson syndrome with intestinal involvement are described. Two patients had esophageal involvement, the severity of which paralleled skin lesions and, in 1 case, probably contributed to death. Dysphagia and bleeding were manifestations. The third patient was unique and had gastric, small and la...

journal_title：Gastroenterology

authors： Zweiban B,Cohen H,Chandrasoma P

更新日期：1986-08-01 00:00:00

abstract：:Sepsis following the placement of a transjugular intrahepatic portosystemic shunt (TIPS) has been reported in up to 10% of cases. This report describes an unusual case of polymicrobial gram-negative sepsis after placement of TIPS associated with a cholangiographically documented fistulous connection between the biliar...

journal_title：Gastroenterology

authors： Mallery S,Freeman ML,Peine CJ,Miller RP,Stanchfield WR

更新日期：1996-11-01 00:00:00

abstract：:The effects of some newly developed tachykinin antagonists that are selective for the neurokinin (NK)-1 (L 668,169) or the NK-2 (MEN 10,207, L 659,877 and R 396) tachykinin receptor on the cholinergic and noncholinergic contraction and on the nonadrenergic noncholinergic relaxation produced by electrical field stimula...

journal_title：Gastroenterology

authors： Maggi CA,Giuliani S,Patacchini R,Santicioli P,Theodorsson E,Barbanti G,Turini D,Giachetti A

更新日期：1992-01-01 00:00:00

abstract：:Inflammasomes are multi-protein complexes that mediate activation of caspase-1, which promotes secretion of the proinflammatory cytokines interleukin-1β and interleukin-18 and pyroptosis, a form of phagocyte cell death induced by bacterial pathogens. Members of the Nod-like receptor family (including Nlrp1, Nlrp3, and...

journal_title：Gastroenterology

authors： Chen GY,Núñez G

更新日期：2011-12-01 00:00:00

abstract：:Electronic (video) endoscopes are a significant new development in gastroenterology, offering the potential of enhanced teaching and permanent storage of pictorial data. The primary concern of gastroenterologists is the resolution and color performance of these instruments, as these parameters have important bearings ...

journal_title：Gastroenterology

authors： Knyrim K,Seidlitz H,Vakil N,Hagenmüller F,Classen M

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The mammalian intestinal epithelium self-renews rapidly and homeostasis is preserved via tightly controlled mechanisms. Long noncoding RNAs transcribed from ultraconserved regions (T-UCRs) control different cell functions, but little is known about their role in maintaining the integrity of the inte...

journal_title：Gastroenterology

authors： Xiao L,Wu J,Wang JY,Chung HK,Kalakonda S,Rao JN,Gorospe M,Wang JY

更新日期：2018-02-01 00:00:00

abstract：:Endoscopic sphincterotomy has proven to be a safe alternative to surgery for selected types of biliary disease. Despite a relatively low morbidity, postprocedure complications are well described. This report presents an experience with three patients in whom acute relapsing pancreatitis developed as a possible complic...

journal_title：Gastroenterology

authors： Asbun HJ,Rossi RL,Heiss FW,Shea JA

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND & AIMS:Peroxynitrite (PN), a potent oxidant, has been implicated in the pathogenesis of gut inflammation and epithelial cell apoptosis. The aim of this study was to investigate mesalamine, a standard therapy for inflammatory bowel disease, to see if it attenuates PN-induced cytotoxicity in human intestinal e...

journal_title：Gastroenterology

authors： Sandoval M,Liu X,Mannick EE,Clark DA,Miller MJ

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND AND AIMS:Antibodies directed against oligomannose sequences alpha-1,3 Man (alpha-1,2 Man alpha-1,2 Man)(n) (n = 1 or 2), termed anti-Saccharomyces cerevisiae antibodies (ASCAs) are markers of Crohn's disease (CD). S. cerevisiae mannan, which expresses these haptens, is used to detect ASCA, but the exact immu...

journal_title：Gastroenterology

authors： Standaert-Vitse A,Jouault T,Vandewalle P,Mille C,Seddik M,Sendid B,Mallet JM,Colombel JF,Poulain D

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND/AIMS:Both hemorrhagic and cardiogenic shock are associated with hepatic shock gene expression at resuscitation. This study investigated the potential role of intravascular superoxide anion as a proximal trigger of heat shock protein gene expression. METHODS:Preanesthetized pigs were subjected to 120 m of to...

journal_title：Gastroenterology

authors： Schoeniger LO,Andreoni KA,Ott GR,Risby TH,Bulkley GB,Udelsman R,Burdick JF,Buchman TG

更新日期：1994-01-01 00:00:00

abstract：:Enteroglucagon-containing cells have been maintained in short-term culture, and the morphologic characteristics of these cells and their response to selected agents have been determined. After 48 h in culture the ultrastructural appearance of the enteroglucagon-immunoreactive cells showed evidence of polarization with...

journal_title：Gastroenterology

authors： Buchan AM,Barber DL,Gregor M,Soll AH

更新日期：1987-10-01 00:00:00

abstract：:The effect of neuropeptide Y on the motor activity of the circular and longitudinal muscle of the guinea pig small intestine was investigated. Neuropeptide Y (0.3-30 nM) inhibited, in a concentration-dependent manner, the ascending enteric reflex contraction of the circular muscle; both the cholinergic and noncholiner...

journal_title：Gastroenterology

authors： Holzer P,Lippe IT,Barthó L,Saria A

更新日期：1987-06-01 00:00:00