Biliary-shunt fistula following transjugular intrahepatic portosystemic shunt placement.

abstract：:Exposure of isolated gastric mucosal surface cells to NH4+ results in acidification of cells as determined by a fluorescent dye technique using acridine orange. The resulting intracellular pH gradient is maintained when cells are suspended in either buffered HCO3- -free Ringer's or choline chloride solution. Cells sus...

journal_title：Gastroenterology

authors： Olender EJ,Fromm D,Furukawa T,Kolis M

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND & AIMS:Intercellular communication through gap junctions has been proposed to be an important mechanism for the maintenance of tissue homeostasis. However, few studies have considered the role of gap junctions in gastric mucosa. The purpose of this study was to evaluate the distribution of gap junction-speci...

journal_title：Gastroenterology

authors： Uchida Y,Matsuda K,Sasahara K,Kawabata H,Nishioka M

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND & AIMS:Patients affected by familial adenomatous polyposis (FAP) are at increased risk of developing duodenal adenomas. In this study, cell proliferation of duodenal mucosa was analyzed to detect kinetic abnormalities related to cancer risk. METHODS:Duodenal biopsy specimens were collected in three groups o...

journal_title：Gastroenterology

authors： Santucci R,Volpe L,Zannoni U,Paganelli GM,Poggi B,Calabrese C,Biasco G

更新日期：1997-10-01 00:00:00

abstract：:A reliable method for studying lead absorption and excretion in rats is described. Lead absorption occurs primarily in theduodenum where lead enters the epithelial mucosal cells. There is a relative mucosal block for lead with increasing intraluminal doses. Certain substances which bind lead and increase its solubilit...

journal_title：Gastroenterology

authors： Conrad ME,Barton JC

更新日期：1978-04-01 00:00:00

abstract：BACKGROUND & AIMS:Nonsteroidal anti-inflammatory drugs (NSAIDs), including aspirin, have been implicated in diverticular complications. We examined the influence of aspirin and NSAID use on risk of diverticulitis and diverticular bleeding in a large prospective cohort. METHODS:We studied 47,210 US men in the Health Pr...

journal_title：Gastroenterology

authors： Strate LL,Liu YL,Huang ES,Giovannucci EL,Chan AT

更新日期：2011-05-01 00:00:00

abstract：:Numerous epidemiologic studies suggest a relationship between lung cancer and peptic ulcer disease. Furthermore, various lung cancers synthesize and release a number of peptides such as gastrin and gastrin-releasing peptide that could cause acid hypersecretion; however, Zollinger-Ellison syndrome (ZES), because of a l...

journal_title：Gastroenterology

authors： Abou-Saif A,Lei J,McDonald TJ,Chakrabarti S,Waxman IF,Shojamanesh H,Schrump DS,Kleiner DE,Gibril F,Jensen RT

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND & AIMS:Omeprazole is metabolized by cytochrome P450 (CYP2C19). The activity of this enzyme is polymorphic, with incidences of poor metabolizers (PMs), heterozygous extensive metabolizers (EMs), and homozygous EMs in white populations of 3%, 30%, and 67%, respectively. The importance of the CYP2C19 polymorphi...

journal_title：Gastroenterology

authors： Sagar M,Tybring G,Dahl ML,Bertilsson L,Seensalu R

更新日期：2000-09-01 00:00:00

abstract：:Interstitial pneumonitis is an uncommon complication of low-dose methotrexate therapy in patients with psoriasis but occurs in 3%-5% of patients with rheumatoid arthritis. We found a higher incidence of interstitial pneumonitis in patients with primary biliary cirrhosis (14%) and describe its clinical manifestations, ...

journal_title：Gastroenterology

authors： Sharma A,Provenzale D,McKusick A,Kaplan MM

更新日期：1994-07-01 00:00:00

abstract：BACKGROUND & AIMS:Regulatory cytokines mediate intestinal epithelial cell (IEC) participation in mucosal immune responses. The aim of this study was to investigate the expression of secretory and intracellular isoforms of interleukin 1 receptor antagonist (IL-1Ra) in human primary IECs and carcinoma-derived cell lines....

journal_title：Gastroenterology

authors： Böcker U,Damião A,Holt L,Han DS,Jobin C,Panja A,Mayer L,Sartor RB

更新日期：1998-12-01 00:00:00

abstract：:The published world literature on the efficacy of cimetidine, a histamine H2-receptor antagonist, in the treatment of duodenal ulcer is reviewed. In eight prospective randomized double blind placebo-controlled studies, cimetidine was administered to 348 duodenal ulcer patients with an incidence of endoscopically verif...

journal_title：Gastroenterology

authors： Winship DH

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND & AIMS:Chronic pancreatitis has been suggested as a causal risk factor for pancreatic cancer in a recent study. The aim of this study was to clarify the relationship between chronic pancreatitis and pancreatic cancer. METHODS:All patients in the Swedish inpatient Register with a discharge diagnosis of pancr...

journal_title：Gastroenterology

authors： Karlson BM,Ekbom A,Josefsson S,McLaughlin JK,Fraumeni JF Jr,Nyrén O

更新日期：1997-08-01 00:00:00

abstract：:Sporadic colorectal cancer (CRC) is a somatic genetic disease in which pathogenesis is influenced by the local colonic environment and the patient's genetic background. Consolidating the knowledge of genetic and epigenetic events that occur with initiation, progression, and metastasis of sporadic CRC has identified so...

journal_title：Gastroenterology

authors： Carethers JM,Jung BH

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:The prognosis of advanced cirrhosis due to chronic hepatitis B is poor, and results of therapies, including liver transplantation, have been unsatisfactory. Little is known about the effectiveness of interferon alfa in patients with cirrhosis. METHODS:Between 1984 and 1991, 18 patients with clinically-appar...

journal_title：Gastroenterology

authors： Hoofnagle JH,Di Bisceglie AM,Waggoner JG,Park Y

更新日期：1993-04-01 00:00:00

abstract：:A 14-yr-old girl presented with long-standing symptoms of partial gastric outlet obstruction due to an antral mucosal diaphragm that had a central aperture of 4-5 mm. The literature of this congenital malformation is reviewed with respect to diagnostic criteria and feasibility of endoscopic transection. The procedure ...

journal_title：Gastroenterology

authors： Berr F,Rienmueller R,Sauerbruch T

更新日期：1985-11-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with chronic hepatitis C and persistently normal alanine aminotransferase (ALT) levels have been routinely excluded from large randomized treatment trials; consequently, the efficacy and safety of antiviral therapy in this population are unknown. METHODS:Patients with at least 3 normal ALT v...

journal_title：Gastroenterology

authors： Zeuzem S,Diago M,Gane E,Reddy KR,Pockros P,Prati D,Shiffman M,Farci P,Gitlin N,O'Brien CB,Lamour F,Lardelli P,PEGASYS Study NR16071 Investigator Group.

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Mutant hepatitis B virus is often associated with severe liver damage. The purpose of this study is to elucidate the relationship between mutations in hepatitis B precore/core gene and the severity of liver damage. METHODS:The hepatitis B precore/core gene from 20 patients with chronic hepatitis B virus inf...

journal_title：Gastroenterology

authors： Chuang WL,Omata M,Ehata T,Yokosuka O,Ito Y,Imazeki F,Lu SN,Chang WY,Ohto M

更新日期：1993-01-01 00:00:00

abstract：:In dogs provided with Heidenhain pouch and gastric fistula, we studied the effect of near-total excision of the fundic mucosa of the main stomach on acid secretion and gastrin release. Fundic mucosal excision abolished the mean response of the gastric fistula and reduced its maximal response to pentagastrin and to his...

journal_title：Gastroenterology

authors： Soon-Shiong P,Debas HT

更新日期：1980-11-01 00:00:00

abstract：:The goal of this study was to identify the structural and compositional features of human gallstones that influence in vitro gallstone dissolution in the cholesterol solvent monooctanoin. Gallstones were obtained from 86 consecutive patients who had at least three morphologically similar stones. One stone from each pa...

journal_title：Gastroenterology

authors： Smith BF

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND & AIMS:Rats fed ethanol at a constant rate through a permanent intragastric cannula have a regular fluctuation in blood alcohol level (BAL) and urine alcohol level (UAL). The level of ethanol peaks every 6-10 days. The question is how the liver differs at the peaks and troughs of the UAL cycle. Hypoxic injur...

journal_title：Gastroenterology

authors： Bardag-Gorce F,French BA,Li J,Riley NE,Yuan QX,Valinluck V,Fu P,Ingelman-Sundberg M,Yoon S,French SW

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND & AIMS:Esophageal adenocarcinoma (EA) and its premalignant lesion, Barrett's esophagus (BE), are characterized by a strong and yet unexplained male predominance (with a male-to-female ratio in EA incidence of up to 6:1). Genome-wide association studies (GWAS) have identified more than 20 susceptibility loci ...

journal_title：Gastroenterology

authors： Dong J,Maj C,Tsavachidis S,Ostrom QT,Gharahkhani P,Anderson LA,Wu AH,Ye W,Bernstein L,Borisov O,Schröder J,Chow WH,Gammon MD,Liu G,Caldas C,Pharoah PD,Risch HA,May A,Gerges C,Anders M,Venerito M,Schmidt T,Izbi

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND & AIMS:The integrin alpha(4)beta(7) mediates homing of effector/memory lymphocytes to the intestine and the mucosa-associated lymphoid tissue. This study examined the ability of alpha(4)beta(7)(hi) CD4(+) T lymphocytes to home to the stomach and their role in immunization-mediated protection against Helicoba...

journal_title：Gastroenterology

authors： Michetti M,Kelly CP,Kraehenbuhl JP,Bouzourene H,Michetti P

更新日期：2000-07-01 00:00:00

abstract：BACKGROUND & AIMS:Lamivudine inhibits hepatitis B virus replication. This study investigated 6 months of lamivudine treatment at three doses. METHODS:Fifty-one patients (43% white, 49% Asian) with chronic hepatitis B were randomly assigned to receive 25, 100, or 300 mg of lamivudine orally once daily for 24 weeks with...

journal_title：Gastroenterology

authors： Nevens F,Main J,Honkoop P,Tyrrell DL,Barber J,Sullivan MT,Fevery J,De Man RA,Thomas HC

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND & AIMS:Gastric histology is not well studied in patients with Crohn's disease. The aim of this study was to analyze the histological appearance of gastric mucosa in patients with Crohn's disease. METHODS:In a prospective study, biopsy specimens taken from the antrum and body of 75 patients with known Crohn'...

journal_title：Gastroenterology

authors： Oberhuber G,Püspök A,Oesterreicher C,Novacek G,Zauner C,Burghuber M,Vogelsang H,Pötzi R,Stolte M,Wrba F

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND & AIMS:Abnormal processing of visceral sensation at the level of the central nervous system is believed to be involved in functional dyspepsia. However, compared with studies of stimulation-related changes in brain activity, few studies have focused on resting brain activity, which also is important in patho...

journal_title：Gastroenterology

authors： Zeng F,Qin W,Liang F,Liu J,Tang Y,Liu X,Yuan K,Yu S,Song W,Liu M,Lan L,Gao X,Liu Y,Tian J

更新日期：2011-08-01 00:00:00

abstract：:We studied the effect of chronic aspirin ingestion on gastroduodenal epithelial proliferation by feeding rats aspirin in the drinking water. A control group of rats received plain water. At the end of 4 wk, [3H]-thymidine was given intravenously to label proliferating cells, and the rats were killed 1 h later. Section...

journal_title：Gastroenterology

authors： Eastwood GL,Quimby GF

更新日期：1982-05-01 00:00:00

abstract：BACKGROUND & AIMS:Microsatellite instability is a property of most tumors occurring in the context of hereditary nonpolyposis colon cancer. Instability also occurs in 10%-15% of apparently sporadic colorectal cancers, and it has been hypothesized that this instability may indicate a genetic predisposition to colonic ca...

journal_title：Gastroenterology

authors： Samowitz WS,Slattery ML,Kerber RA

更新日期：1995-12-01 00:00:00

abstract：:The diagnosis of inflammatory bowel disease (IBD) with its 2 main subforms, Crohn's disease and ulcerative colitis, is based on clinical, endoscopic, radiologic, and histologic criteria. This paradigm remains unchanged despite the advent of new molecular technologies for the examination of serum proteins and genetic s...

journal_title：Gastroenterology

authors： Nikolaus S,Schreiber S

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND & AIMS:Unlike adult antral cells, feline newborn antral cells are unable to contract in response to agonists in the absence of extracellular calcium or in response to exogenous inositol 1,4,5-triphosphate (IP3) after permeabilization. Changes in intracellular pathways that are associated with these differenc...

journal_title：Gastroenterology

authors： Hillemeier AC,Deutsch DE,Bitar KN

更新日期：1997-08-01 00:00:00

abstract：:A randomized, controlled trial was conducted to investigate the ability of indomethacin and chloroquine to reduce intestinal secretion in 29 adult patients with severe cholera. All patients received intravenous infusion to restore fluid balance, but no antibiotics were given. Patients treated with oral indomethacin (t...

journal_title：Gastroenterology

authors： Rabbani GH,Butler T

更新日期：1985-11-01 00:00:00

abstract：:Although nocturnal acid secretion has been emphasized in the pathophysiology and treatment of duodenal ulcer, its importance in gastric ulcer disease has been questioned. To explore this area, this multicenter U.S. trial compared the effect of a once-daily nighttime dose of H2-receptor antagonist with placebo on the h...

journal_title：Gastroenterology

authors： McCullough AJ,Graham DY,Knuff TE,Lanza FL,Levenson HL,Lyon DT,Munsell WP,Perozza J,Roufail WM,Sinar DR

更新日期：1989-10-01 00:00:00