Candida albicans is an immunogen for anti-Saccharomyces cerevisiae antibody markers of Crohn's disease.

abstract：BACKGROUND & AIMS:Fecal incontinence (FI) is characterized by uncontrolled passage of solid or liquid stool. We aimed to determine the prevalence and severity of FI in a large sample of US residents. METHODS:We recruited a representative sample of patients in October 2015 to complete the National Gastrointestinal (GI)...

journal_title：Gastroenterology

authors： Menees SB,Almario CV,Spiegel BMR,Chey WD

更新日期：2018-05-01 00:00:00

abstract：:This study of ischemic and postischemic reperfusion intestinal injury in rats evaluates the potential therapeutic value of fructose 1-6 diphosphate on the basis of its ability to enhance anaerobic carbohydrate metabolism during ischemia and to prevent additional tissue injury after reestablishing blood flow by inhibit...

journal_title：Gastroenterology

authors： Sun JX,Farias LA,Markov AK

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND & AIMS:The hypothesis that progastrin-derived peptides act as autocrine growth factors for colorectal carcinomas has generated considerable interest. However, the influence of autocrine gastrins on nontumorigenic colonic cells has not been investigated. This study tested the above hypothesis in the nontumori...

journal_title：Gastroenterology

authors： Hollande F,Imdahl A,Mantamadiotis T,Ciccotosto GD,Shulkes A,Baldwin GS

更新日期：1997-11-01 00:00:00

abstract：:The efficacy of phenobarbital in altering biliary lipid composition in normal man was investigated by determining parameters of biliary lipid metabolism in 8 human subjects without biliary tract disease before and after oral phenobarbital administration at a dose of approximately 3 mg per kg per day for 25 to 54 days....

journal_title：Gastroenterology

authors： Ginsberg RL,Garnick MB

更新日期：1977-06-01 00:00:00

abstract：BACKGROUND & AIMS:Stimulator of Fe Transport (SFT) and transferrin receptor (TfR) are proteins involved in iron transport. This study evaluated iron metabolism protein expression in duodenal biopsy specimens from controls and patients with abnormal iron metabolism. METHODS:Twelve controls, 8 patients with iron deficie...

journal_title：Gastroenterology

authors： Barisani D,Parafioriti A,Armiraglio E,Meneveri R,Conte D

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND & AIMS:Activated pancreatic stellate cells have recently been implicated in pancreatic fibrogenesis. This study examined the role of pancreatic stellate cells in alcoholic pancreatic fibrosis by determining whether these cells are activated by ethanol itself and, if so, whether such activation is caused by t...

journal_title：Gastroenterology

authors： Apte MV,Phillips PA,Fahmy RG,Darby SJ,Rodgers SC,McCaughan GW,Korsten MA,Pirola RC,Naidoo D,Wilson JS

更新日期：2000-04-01 00:00:00

abstract：:In fed rats, acid production was estimated to be 7 X 10(8) molecules of HCl per cell per sec or 5 X 10(5) molecules per sec per mu2 of secretory surface. In stimulated frog mucosa the corresponding values were 3 X 10(8) molecules of HCl per cell per sec 2 X 10(5) molecules per sec per mu2 or secretory surface. The gen...

journal_title：Gastroenterology

authors： Helander HF

更新日期：1977-10-01 00:00:00

abstract：:A numerically important group of patients with functional gastrointestinal disorders have chronic symptoms that can be attributed to the gastroduodenal region. Based on the consensus opinion of an international panel of clinical investigators who reviewed the available evidence, a classification of the functional gast...

journal_title：Gastroenterology

authors： Tack J,Talley NJ,Camilleri M,Holtmann G,Hu P,Malagelada JR,Stanghellini V

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND & AIMS:Pancreatic cancers contain exclusively tumorigenic cancer stem cells (CSCs), which are highly resistant to chemotherapy, resulting in a relative increase in CSC numbers during gemcitabine treatment. Signaling through sonic hedgehog and mammalian target of rapamycin (mTOR), respectively, may be essenti...

journal_title：Gastroenterology

authors： Mueller MT,Hermann PC,Witthauer J,Rubio-Viqueira B,Leicht SF,Huber S,Ellwart JW,Mustafa M,Bartenstein P,D'Haese JG,Schoenberg MH,Berger F,Jauch KW,Hidalgo M,Heeschen C

更新日期：2009-09-01 00:00:00

abstract：BACKGROUND & AIMS:A Western-style diet, which is high in fat and sugar, can cause significant dyslipidemia and nonalcoholic fatty liver disease; the diet has an especially strong effect in women, regardless of total calorie intake. Dietary supplementation with beneficial microbes might reduce the detrimental effects of...

journal_title：Gastroenterology

authors： Naudin CR,Maner-Smith K,Owens JA,Wynn GM,Robinson BS,Matthews JD,Reedy AR,Luo L,Wolfarth AA,Darby TM,Ortlund EA,Jones RM

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND & AIMS:Therapies for perianal fistulas in patients with Crohn's disease are often ineffective in producing long-term healing. We performed a randomized placebo-controlled trial to determine the long-term efficacy and safety of a single local administration of allogeneic expanded adipose-derived stem cells (C...

journal_title：Gastroenterology

authors： Panés J,García-Olmo D,Van Assche G,Colombel JF,Reinisch W,Baumgart DC,Dignass A,Nachury M,Ferrante M,Kazemi-Shirazi L,Grimaud JC,de la Portilla F,Goldin E,Richard MP,Diez MC,Tagarro I,Leselbaum A,Danese S,ADMIRE CD St

更新日期：2018-04-01 00:00:00

abstract：:This paper describes an ultrasound method of assessing gastric emptying time based on measurements of the gastric antrum, which is visible in almost all subjects before and after meals. A total of 54 subjects were examined including 18 normal subjects and 36 subjects with idiopathic functional dyspepsia. The emptying ...

journal_title：Gastroenterology

authors： Bolondi L,Bortolotti M,Santi V,Calletti T,Gaiani S,Labò G

更新日期：1985-10-01 00:00:00

abstract：BACKGROUND & AIMS:Recurrence of varices and rebleeding after endoscopic therapy is very common. Data on the prediction of recurrent varices after initial obliteration by endoscopic therapy are few. The aim of this study was to correlate the presence and the size of paraesophageal varices (PEVs) in patients after endosc...

journal_title：Gastroenterology

authors： Leung VK,Sung JJ,Ahuja AT,Tumala IE,Lee YT,Lau JY,Chung SC

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND & AIMS:Liver X receptors (LXRs) are transcriptional regulators of cholesterol metabolism, controlling cholesterol flow into cells, catabolism, and efflux. Cholesterol controls cell proliferation; disruptions in cholesterol metabolism have been associated with the development of colon cancer. We investigated ...

journal_title：Gastroenterology

authors： Lo Sasso G,Bovenga F,Murzilli S,Salvatore L,Di Tullio G,Martelli N,D'Orazio A,Rainaldi S,Vacca M,Mangia A,Palasciano G,Moschetta A

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND & AIMS:A random biopsy is recommended for surveillance of ulcerative colitis (UC)-associated colorectal cancer. However, a targeted biopsy might be more effective. We conducted a randomized controlled trial to compare rates of neoplasia detection by targeted vs random biopsies in patients with UC. METHODS:W...

journal_title：Gastroenterology

authors： Watanabe T,Ajioka Y,Mitsuyama K,Watanabe K,Hanai H,Nakase H,Kunisaki R,Matsuda K,Iwakiri R,Hida N,Tanaka S,Takeuchi Y,Ohtsuka K,Murakami K,Kobayashi K,Iwao Y,Nagahori M,Iizuka B,Hata K,Igarashi M,Hirata I,Kudo S

更新日期：2016-12-01 00:00:00

abstract：:A patient with the acquired immunodeficiency syndrome (AIDS) with a cytomegalovirus (CMV) infection localized in the area of an ileal Kaposi sarcoma resulting in perforation is described. Because only one case of such an association of Kaposi sarcoma with CMV leading to perforation has been reported, the presence and ...

journal_title：Gastroenterology

authors： Genta RM,Bleyzer I,Cate TR,Tandon AK,Yoffe B

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND & AIMS:The physiologic significance of the M(3) muscarinic receptor is unclear due to an absence of specific ligand. In the present study, M(3) receptor knockout (KO) mice were used to elucidate the role of M(3) receptors in gastric acid secretion and gastric mucosal integrity. METHODS:M(3) KO versus wild-t...

journal_title：Gastroenterology

authors： Aihara T,Fujishita T,Kanatani K,Furutani K,Nakamura E,Taketo MM,Matsui M,Chen D,Okabe S

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND & AIMS:Little is known about substitutions that mediate resistance of hepatitis C virus (HCV) to direct-acting antivirals (DAAs), due to the small number of patients with treatment failure in approval studies. It is important to identify resistance patterns to select effective salvage treatments. METHODS:We...

journal_title：Gastroenterology

authors： Dietz J,Susser S,Vermehren J,Peiffer KH,Grammatikos G,Berger A,Ferenci P,Buti M,Müllhaupt B,Hunyady B,Hinrichsen H,Mauss S,Petersen J,Buggisch P,Felten G,Hüppe D,Knecht G,Lutz T,Schott E,Berg C,Spengler U,von Ha

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Actin is a key contractile protein associated with the normal differentiation and function of gastrointestinal smooth muscle cells. Distinct changes in gastrointestinal smooth muscle cell morphology and function have been reported for the aganglionic rectum and megacolon of the adult lethal spotted mouse. Th...

journal_title：Gastroenterology

authors： Liddell RA,Mooers SU,Siegman MJ,McHugh KM

更新日期：1993-08-01 00:00:00

abstract：:Interleukin 2, a soluble product of activated T lymphocytes, is of central importance in the development of an appropriate T-cell immune response. Defects in the production of or response to this lymphokine have been described in a variety of immune deficiency and autoimmune states, thus suggesting a role in the patho...

journal_title：Gastroenterology

authors： Fiocchi C,Hilfiker ML,Youngman KR,Doerder NC,Finke JH

更新日期：1984-04-01 00:00:00

abstract：BACKGROUND/AIMS:Despite putative roles of calcium in biliary physiology and gallstone formation, quantitative aspects of calcium binding to bile salt (BS) monomers, simple micelles, mixed micelles, and vesicles, which constitute the lipid aggregates in bile, remain unexplored. METHODS:Calcium activity was measured usi...

journal_title：Gastroenterology

authors： Donovan JM,Leonard MR,Batta AK,Carey MC

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND & AIMS:ob/ob mice are used to study the mechanisms that regulate the progression from steatosis to nonalcoholic steatohepatitis. The livers of ob/ob mice are depleted of CD4-positive natural killer cells, components of the innate immune system that induce anti-inflammatory cytokines. Although this may explai...

journal_title：Gastroenterology

authors： Li Z,Lin H,Yang S,Diehl AM

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND & AIMS:Our aim was to investigate the relationship between alcohol consumption and iron overload, iron deficiency, or iron deficiency anemia in the U.S. population. METHODS:Adult participants of the Third National Health and Nutrition Examination Survey who did not consume alcohol (n = 8839) were compared w...

journal_title：Gastroenterology

authors： Ioannou GN,Dominitz JA,Weiss NS,Heagerty PJ,Kowdley KV

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND & AIMS:Infection with Tropheryma whipplei has a range of effects-some patients can be chronic carriers without developing any symptoms, whereas others can develop systemic Whipple disease, characterized by a lack a protective inflammatory immune response. Alterations in HLA-G function have been associated wi...

journal_title：Gastroenterology

authors： Ben Azzouz E,Boumaza A,Mezouar S,Bardou M,Carlini F,Picard C,Raoult D,Mège JL,Desnues B

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND & AIMS:Diets high in fructose have been proposed to contribute to nonalcoholic fatty liver disease. We compared the effects of high-fructose and matched glucose intake on hepatic triacylglycerol (TAG) concentration and other liver parameters. DESIGN:In a double-blind study, we randomly assigned 32 healthy b...

journal_title：Gastroenterology

authors： Johnston RD,Stephenson MC,Crossland H,Cordon SM,Palcidi E,Cox EF,Taylor MA,Aithal GP,Macdonald IA

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND/AIMS:Reflex relaxation is a mechanism whereby the colon can show short-term dilatation in the absence of mechanical obstruction. This study investigated the tonic response of the canine colon to ileal distention and its pharmacological control. METHODS:In four dogs, the tone of the proximal colon was record...

journal_title：Gastroenterology

authors： Basilisco G,Phillips SF

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND & AIMS:Leptin production has been reported in the rat and in human stomach. It initiates intestinal nutrient absorption. In this study, we analyzed the effect of vagal stimulation on leptin release in the human stomach. METHODS:We studied the secretion of gastric acid and leptin on stimulation with insulin ...

journal_title：Gastroenterology

authors： Sobhani I,Buyse M,Goïot H,Weber N,Laigneau JP,Henin D,Soul JC,Bado A

更新日期：2002-02-01 00:00:00

abstract：:We describe the clinical and laboratory features of a case of spontaneous bacterial peritonitis caused by Neisseria gonorrhoeae in a sexually active woman with Laennec's cirrhosis, ascites, and asymptomatic cervical gonorrhea. Treatment of the infection with high-dose parenteral penicillin was associated with resoluti...

journal_title：Gastroenterology

authors： Stassen WN,McCullough AJ,Hilton PK

更新日期：1985-03-01 00:00:00

abstract：:The clinical, functional, and histopathological effects of 18 g additional gluten intake daily for 4 wk was studied in 13 healthy siblings of Spanish children with celiac disease, including two pairs of discordant monozygotic twins. Five of the 13 children were HLA-DR identical to the celiac sibling, 5 shared only one...

journal_title：Gastroenterology

authors： Polanco I,Mearin ML,Larrauri J,Biemond I,Wipkink-Bakker A,Peña AS

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Factors associated with the development and malignant progression of Barrett's esophagus are poorly understood. Gastrin is a mitogen capable of inducing growth in normal and malignant gastrointestinal mucosa. It is unknown whether gastrin can influence cellular events in the esophagus in Barrett's. ...

journal_title：Gastroenterology

authors： Haigh CR,Attwood SE,Thompson DG,Jankowski JA,Kirton CM,Pritchard DM,Varro A,Dimaline R

更新日期：2003-03-01 00:00:00