Large paraesophageal varices on endosonography predict recurrence of esophageal varices and rebleeding.

abstract：:Abdominal cramps and urgent defecation are common side effects of clinical doses of arginine vasopressin, indicating that the drug may have stimulating effects on colonic motor activity. Four strain-gauge transducers were implanted on the colon in six monkeys. A blood flow probe was fixed on the inferior mesenteric ar...

journal_title：Gastroenterology

authors： Zhu YR,Cowles VE,Herranz ES,Schulte WJ,Condon RE

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND & AIMS:Conventional transarterial chemoembolization (cTACE) is used to treat patients with hepatocellular carcinoma (HCC). Radioembolization is a minimally invasive procedure that involves implantation of radioactive micron-sized particles loaded with yttrium-90 (Y90) inside the blood vessels that supply a t...

journal_title：Gastroenterology

authors： Salem R,Gordon AC,Mouli S,Hickey R,Kallini J,Gabr A,Mulcahy MF,Baker T,Abecassis M,Miller FH,Yaghmai V,Sato K,Desai K,Thornburg B,Benson AB,Rademaker A,Ganger D,Kulik L,Lewandowski RJ

更新日期：2016-12-01 00:00:00

abstract：BACKGROUND & AIMS:Genetic factors are believed to affect risk for irritable bowel syndrome (IBS), but there have been no sufficiently powered and adequately sized studies. To identify DNA variants associated with IBS risk, we performed a genome-wide association study (GWAS) of the large UK Biobank population-based coho...

journal_title：Gastroenterology

authors： Bonfiglio F,Zheng T,Garcia-Etxebarria K,Hadizadeh F,Bujanda L,Bresso F,Agreus L,Andreasson A,Dlugosz A,Lindberg G,Schmidt PT,Karling P,Ohlsson B,Simren M,Walter S,Nardone G,Cuomo R,Usai-Satta P,Galeazzi F,Neri M,P

更新日期：2018-07-01 00:00:00

abstract：BACKGROUND & AIMS:Monocytes/macrophages infiltrate into injured livers. We tried to clarify their roles in inflammation and subsequent fibrogenesis by inhibiting their infiltration with a mutated form (7ND; 7 amino acids at the N-terminal were deleted) of monocyte chemoattractant protein 1, which may function as a domi...

journal_title：Gastroenterology

authors： Imamura M,Ogawa T,Sasaguri Y,Chayama K,Ueno H

更新日期：2005-01-01 00:00:00

abstract：:We investigated a hormonal mechanism in a trypsin inhibitor-induced pancreatic hypersecretion in rats. Intraduodenal administration of a synthetic trypsin inhibitor, camostat, resulted in significant increases in plasma concentration of both secretin and cholecystokinin in a dose-related manner that paralleled a signi...

journal_title：Gastroenterology

authors： Watanabe S,Takeuchi T,Chey WY

更新日期：1992-02-01 00:00:00

abstract：:The effects of hydroxypropylmethylcellulose on upper gastrointestinal transit, viscosity, and water flux were studied in six dogs fistulated at the proximal duodenum and/or mid-jejunum. Combinations of different grades of hydroxypropylmethylcellulose were prepared as 2% or 3.3% solutions to yield input viscosities of ...

journal_title：Gastroenterology

authors： Reppas C,Meyer JH,Sirois PJ,Dressman JB

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND & AIMS:Colorectal cancer screening with diagnostic imaging can detect polyps. The management of patients whose largest polyp is less than 10 mm is uncertain. The primary aim of this study was to determine rates of advanced histology in patients undergoing colorectal cancer screening whose largest polyp is 9 ...

journal_title：Gastroenterology

authors： Lieberman D,Moravec M,Holub J,Michaels L,Eisen G

更新日期：2008-10-01 00:00:00

abstract：:The management of colon polyps has been completely revolutionized since the introduction of colonoscopic polypectomy. The reductions in patient time, cost, morbidity, and mortality are major advantages. Reported complications include primarily hemorrhage (1.7%) and frank clinical perforation (0.32%). This report descr...

journal_title：Gastroenterology

authors： Overholt BF,Hargrove RL,Farris RK,Wilson BM

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND & AIMS:Several aspects of the pathogenesis of osteopenia in celiac disease are still unclear. Therefore, bone mass and metabolism were evaluated in adults with celiac disease in a cross-sectional study. METHODS:Bone mineral density (BMD), assessed by total body dual-photon absorptiometry, and serum indices ...

journal_title：Gastroenterology

authors： Corazza GR,Di Sario A,Cecchetti L,Tarozzi C,Corrao G,Bernardi M,Gasbarrini G

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND & AIMS:The rate of 12alpha-hydroxylation of bile acid intermediates is believed to determine the ratio of cholic acid (CA) to chenodeoxycholic acid (CDCA) biosynthesis and the overall hydrophobicity of the bile acid pool. The aim of this study was to determine the effects of the level of expression of sterol...

journal_title：Gastroenterology

authors： Pandak WM,Bohdan P,Franklund C,Mallonee DH,Eggertsen G,Björkhem I,Gil G,Vlahcevic ZR,Hylemon PB

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND & AIMS:The effects of parenteral growth hormone, glutamine supplementation, and a high carbohydrate-low fat (HCLF) diet on gut adaptation in short-bowel syndrome are unclear. The aim of this study was to compare effects of this treatment regimen and placebo in patients with short-bowel syndrome. METHODS:A r...

journal_title：Gastroenterology

authors： Scolapio JS,Camilleri M,Fleming CR,Oenning LV,Burton DD,Sebo TJ,Batts KP,Kelly DG

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatobiliary secretion is generally believed to be an integral step in the pathway of cholesterol excretion from the body. Here we have investigated the validity of this paradigm in mice. METHODS:Cholesterol balance was assessed by measuring intake, excretion, and biliary output in different mouse m...

journal_title：Gastroenterology

authors： van der Velde AE,Vrins CL,van den Oever K,Kunne C,Oude Elferink RP,Kuipers F,Groen AK

更新日期：2007-09-01 00:00:00

abstract：:In these studies we compared jejunal permeability to two probes--chromium 51-labeled ethylenediaminetetraacetic acid (51Cr-EDTA) (mol wt, 360) and ovalbumin (mol wt, 45,000)--under control conditions, during acute intestinal inflammation, and in response to systemic anaphylaxis. Acute inflammation was produced after i...

journal_title：Gastroenterology

authors： Ramage JK,Stanisz A,Scicchitano R,Hunt RH,Perdue MH

更新日期：1988-06-01 00:00:00

abstract：:A recent study reports that patients with previous acute pancreatitis commonly have an abnormal clearance of serum triglycerides after an oral fat load. This observation supports the hypothesis that patients with previous acute pancreatitis and normal fasting serum triglyceride levels may have a preexistent abnormalit...

journal_title：Gastroenterology

authors： Rollán A,Guzmán S,Pimentel F,Nervi F

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND & AIMS:Viral genotypes have been associated with different severity and outcome of hepatitis C virus (HCV)-related liver disease. The aim of this study was to determine whether HCV genotypes may influence the cirrhosis-related risk of the development of hepatocellular carcinoma (HCC). METHODS:Three groups o...

journal_title：Gastroenterology

authors： Silini E,Bottelli R,Asti M,Bruno S,Candusso ME,Brambilla S,Bono F,Iamoni G,Tinelli C,Mondelli MU,Ideo G

更新日期：1996-07-01 00:00:00

abstract：BACKGROUND & AIMS:The effect of endogenous hypergastrinemia on growth of human colon carcinoma is not known. Our aim was to study the growth of human colon carcinoma in an animal model with endogenous hypergastrinemia. METHODS:Human colon carcinoma was transplanted to the colon of 40 athymic rats. Of these, 25 underwe...

journal_title：Gastroenterology

authors： Chu M,Nielsen FC,Franzén L,Rehfeld JF,Holst JJ,Borch K

更新日期：1995-11-01 00:00:00

abstract：:Approximately 10% of persons 70 years old or older are now diagnosed with pancreatic cysts, but it is not clear which ones require additional analysis, interventions, or follow-up. Primary care doctors rely on gastroenterologists for direction because no one wants to miss a diagnosis of pancreatic cancer, but meanwhil...

journal_title：Gastroenterology

authors： Farrell JJ,Fernández-del Castillo C

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND & AIMS:Chronic hepatitis C virus (HCV) infection is a major burden on individuals and health care systems. The Extension for Community Healthcare Outcomes (Project ECHO) enables primary care providers to deliver best-practice care for complex conditions to underserved populations. The US Congress passed the ...

journal_title：Gastroenterology

authors： Rattay T,Dumont IP,Heinzow HS,Hutton DW

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND/AIMS:The neuropeptide somatostatin exerts multiple functions in the gastrointestinal tract and may also play a regulatory role in inflammatory bowel disease, as several other neuropeptides do, e.g., substance P or calcitonin gene-related peptide. Therefore, the expression of somatostatin receptors was evalua...

journal_title：Gastroenterology

authors： Reubi JC,Mazzucchelli L,Laissue JA

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND & AIMS:Congenital tufting enteropathy (CTE) is a rare autosomal recessive diarrheal disorder presenting in the neonatal period. CTE is characterized by intestinal epithelial cell dysplasia leading to severe malabsorption and significant morbidity and mortality. The pathogenesis and genetics of this disorder ...

journal_title：Gastroenterology

authors： Sivagnanam M,Mueller JL,Lee H,Chen Z,Nelson SF,Turner D,Zlotkin SH,Pencharz PB,Ngan BY,Libiger O,Schork NJ,Lavine JE,Taylor S,Newbury RO,Kolodner RD,Hoffman HM

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND & AIMS:We have few population-level data on the performance of endoscopic retrograde cholangiopancreatography (ERCP) in the United States. We investigated the numbers of unplanned hospital encounters (UHEs), patient and facility factors associated with UHEs, and variation in quality and outcomes in the perfo...

journal_title：Gastroenterology

authors： Huang RJ,Barakat MT,Girotra M,Lee JS,Banerjee S

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND AND AIMS:We set out to test the hypothesis that irritable bowel syndrome (IBS) is characterized by an augmented cellular immune response with enhanced production of proinflammatory cytokines. We further aimed to explore whether symptoms and psychiatric comorbidity in IBS are linked to the release of proinfla...

journal_title：Gastroenterology

authors： Liebregts T,Adam B,Bredack C,Röth A,Heinzel S,Lester S,Downie-Doyle S,Smith E,Drew P,Talley NJ,Holtmann G

更新日期：2007-03-01 00:00:00

abstract：BACKGROUND & AIMS:In one-third of hepatocellular carcinomas (HCCs), cancer cells have mutations that activate β-catenin pathway. These cells have alterations in glutamine, bile, and lipid metabolism. We investigated whether positron emission tomography (PET) imaging allows identification of altered metabolic pathways t...

journal_title：Gastroenterology

authors： Gougelet A,Sartor C,Senni N,Calderaro J,Fartoux L,Lequoy M,Wendum D,Talbot JN,Prignon A,Chalaye J,Imbeaud S,Zucman-Rossi J,Tordjmann T,Godard C,Bossard P,Rosmorduc O,Amaddeo G,Colnot S

更新日期：2019-09-01 00:00:00

abstract：BACKGROUND/AIMS:During liver fibrosis, there is a putative pacemaker role of fibronectin. Fibrinogen is closely linked to fibronectin during clotting processes. The aim of this study was to show fibrinogen gene expression during liver damage. METHODS:Fibrinogen/fibrin deposition in damaged livers was studied by immuno...

journal_title：Gastroenterology

authors： Neubauer K,Knittel T,Armbrust T,Ramadori G

更新日期：1995-04-01 00:00:00

abstract：BACKGROUND & AIMS:Wilson disease is a genetic disorder characterized by the accumulation of copper in the body as a result of a defect of copper excretion from hepatocytes. The intracellular localization of the Wilson disease gene product, ATP7B, was recently identified as the late endosomes. Various mutations have bee...

journal_title：Gastroenterology

authors： Harada M,Sakisaka S,Terada K,Kimura R,Kawaguchi T,Koga H,Kim M,Taniguchi E,Hanada S,Suganuma T,Furuta K,Sugiyama T,Sata M

更新日期：2001-03-01 00:00:00

abstract：:Hypercalcemia produced in normal volunteers by intravenous infusions of CaCl2 increased outputs of pancreatic enzyme and gastric acid. Further, hypercalcemia enhanced cholecystokinin (CCK)-stimulated pancreatic enzyme secretion and gallbladder contraction. Our results suggest that hypercalcemia affects pancreatic, gal...

journal_title：Gastroenterology

authors： Malagelada JR,Holtermuller KH,Sizemore GW,Go VL

更新日期：1976-09-01 00:00:00

abstract：BACKGROUND & AIMS:After liver injury, bone marrow-derived liver sinusoidal endothelial cell progenitor cells (BM SPCs) repopulate the sinusoid as liver sinusoidal endothelial cells (LSECs). After partial hepatectomy, BM SPCs provide hepatocyte growth factor, promote hepatocyte proliferation, and are necessary for norma...

journal_title：Gastroenterology

authors： Wang L,Wang X,Wang L,Chiu JD,van de Ven G,Gaarde WA,Deleve LD

更新日期：2012-12-01 00:00:00

abstract：:The polypeptide core of mucin glycoprotein subunits resists cleavage by proteases. To determine if the carbohydrate side chains of these subunits protect the underlying polypeptide core from proteolytic cleavage, we compared the effect of pancreatic proteases on hog gastric mucin before and after cleavage of its carbo...

journal_title：Gastroenterology

authors： Variyam EP,Hoskins LC

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND & AIMS:Long-term data on the risk of colorectal cancer according to dose, duration, and consistency of aspirin therapy are limited. METHODS:We conducted a prospective study of 47,363 male health professionals who were ages 40-75 years at enrollment in 1986. Biennially, we collected data on aspirin use, othe...

journal_title：Gastroenterology

authors： Chan AT,Giovannucci EL,Meyerhardt JA,Schernhammer ES,Wu K,Fuchs CS

更新日期：2008-01-01 00:00:00

abstract：:Osteopenia in the form of osteoporosis is a common clinical problem associated with chronic cholestatic liver disease, and clinical morbidity from atraumatic fractures is increasing as more patients with PBC and PSC undergo successful liver transplantation. In the absence of symptomatic fractures, the clinical diagnos...

journal_title：Gastroenterology

authors： Hay JE

更新日期：1995-01-01 00:00:00