Measurement of gastric emptying time by real-time ultrasonography.

abstract：BACKGROUND & AIMS:We evaluated etanercept, a human soluble tumor necrosis factor receptor: Fc fusion protein, for the treatment of active Crohn's disease. METHODS:Forty-three patients with moderate to severe Crohn's disease were enrolled in an 8-week placebo-controlled trial. Patients were randomized to subcutaneous e...

journal_title：Gastroenterology

authors： Sandborn WJ,Hanauer SB,Katz S,Safdi M,Wolf DG,Baerg RD,Tremaine WJ,Johnson T,Diehl NN,Zinsmeister AR

更新日期：2001-11-01 00:00:00

abstract：:In vivo and in vitro ultrasonic characteristics of gallstones were compared with stone size and composition with the aim of understanding the basis for these features. In vivo and in vitro ultrasonic features of the same stone were identical. Acoustic shadowing was not due to stone type, radiodensity, or calcium conte...

journal_title：Gastroenterology

authors： Good LI,Edell SL,Soloway RD,Trotman BW,Mulhern C,Arger PA

更新日期：1979-08-01 00:00:00

abstract：BACKGROUND:Over 60 studies have addressed the hypothesis that the risk of colorectal cancer is increased following cholecystectomy; these studies have yielded inconsistent findings. The aim of the present study was to quantitatively summarize the results from the collective studies. METHODS:A meta-analysis of the publ...

journal_title：Gastroenterology

authors： Giovannucci E,Colditz GA,Stampfer MJ

更新日期：1993-07-01 00:00:00

abstract：:Endogenous pancreatic prostaglandin production in control and obstructive jaundice was investigated using isolated and perfused dog pancreas. In both groups, spontaneous production of prostaglandin E2 and prostaglandin I2 was recorded, and the levels did not change in both groups. The production of both prostaglandins...

journal_title：Gastroenterology

authors： Kuroda T,Kajikawa S,Hanazaki K,Horigome N,Sodeyama H,Horiuchi A,Iwatsuki K,Chiba S,Homma T,Iida F

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND & AIMS:Approximately 10% of children on the liver transplant wait-list in the United States die every year. We examined deceased donor liver offer acceptance patterns and their contribution to pediatric wait-list mortality. METHODS:We performed a retrospective cohort study of children on the US liver transp...

journal_title：Gastroenterology

authors： Hsu EK,Shaffer ML,Gao L,Sonnenday C,Volk ML,Bucuvalas J,Lai JC

更新日期：2017-10-01 00:00:00

abstract：BACKGROUND & AIMS:Alcohol abuse causes half of all deaths from cirrhosis in the West, but few tools are available for noninvasive diagnosis of alcoholic liver disease. We evaluated 2 elastography techniques for diagnosis of alcoholic fibrosis and cirrhosis; liver biopsy with Ishak score and collagen-proportionate area ...

journal_title：Gastroenterology

authors： Thiele M,Detlefsen S,Sevelsted Møller L,Madsen BS,Fuglsang Hansen J,Fialla AD,Trebicka J,Krag A

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND & AIMS:Intestinal myofibroblasts are known to respond to inflammatory signals and may play a role in Crohn's disease-associated fibrosis. However, putative involvement by myofibroblasts in innate immune responses as part of intestinal host defense has not been characterized. We therefore analyzed expression ...

journal_title：Gastroenterology

authors： Otte JM,Rosenberg IM,Podolsky DK

更新日期：2003-06-01 00:00:00

abstract：:The prevalence of gastroesophageal varices and gastrointestinal hemorrhage was determined in 124 patients with severe chronic active liver disease (CALD) receiving prednisone and followed regularly for up to 10 yr. Varices were demonstrated by contrast radiography in only 19 patients (15%). Ten had varices before ther...

journal_title：Gastroenterology

authors： Czaja AJ,Wolf AM,Summerskill WH

更新日期：1979-10-01 00:00:00

abstract：:Two types of benzodiazepine receptors have been identified in the central nervous system. The aim of these experiments was to determine if ligands for these receptors alter basal water absorption by rat ileum in vivo after central administration. Specifically, the effects on net water flux of the systemic and central ...

journal_title：Gastroenterology

authors： Fogel R,Michelson G,Senler T,Marshall D,Brown T,Gaginella T

更新日期：1987-08-01 00:00:00

abstract：:Hepatocellular carcinoma often affects blacks at an early age. The purpose of this study was to ascertain if the association between chronic hepatitis B virus infection and hepatocellular carcinoma is the same in young and older black patients. Serum markers of hepatitis B infection were measured by radioimmunoassay i...

journal_title：Gastroenterology

authors： Kew MC,Macerollo P

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND & AIMS:Cyclooxygenase 2 (COX-2)-specific inhibitors (coxibs) decrease gastrointestinal (GI) events in controlled trials, but results in clinical practice are unknown. We assessed GI-related resource use and costs in patients switching from chronic nonsteroidal anti-inflammatory drug (NSAID) therapy to chroni...

journal_title：Gastroenterology

authors： Laine L,Wogen J,Yu H

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND & AIMS:The risk for colorectal cancer (CRC) in patients with inflammatory bowel disease (IBD) could have changed over time, with changes in treatment options. We studied CRC risk in a nationwide cohort of 47,374 Danish patients with IBD over a 30-year period. METHODS:We determined relative risk (RR) values ...

journal_title：Gastroenterology

authors： Jess T,Simonsen J,Jørgensen KT,Pedersen BV,Nielsen NM,Frisch M

更新日期：2012-08-01 00:00:00

abstract：:Bacterial extracts were prepared from cultures originating in chronic self-filling intestinal blind loops in rats. Their ability to remove active maltase molecules from isolated brush border membranes was studied in vitro. Twelve strains in 51 tested, belonging to one of three species, Bacteroides fragilis, Clostridiu...

journal_title：Gastroenterology

authors： Jonas A,Krishnan C,Forstner G

更新日期：1978-11-01 00:00:00

abstract：BACKGROUND & AIMS:Previous studies have indicated that serotonin-3-receptor antagonists might have a sex-specific effect in patients with irritable bowel syndrome with diarrhea (IBS-D). Alosetron has been approved for the treatment of only women, and ramosetron has been approved for the treatment for only men. We perfo...

journal_title：Gastroenterology

authors： Fukudo S,Kinoshita Y,Okumura T,Ida M,Akiho H,Nakashima Y,Nishida A,Haruma K

更新日期：2016-02-01 00:00:00

abstract：:Cellular protooncogenes such as c-myc and c-Ha-ras may play important roles in the control of regeneration of the stomach. In this study, in situ hybridization histochemistry and immunohistochemistry were used to determine how these protooncogenes and the corresponding oncoproteins are expressed at the cellular level ...

journal_title：Gastroenterology

authors： Ito T,Hayashi N,Sasaki Y,Morita Y,Kawano S,Fusamoto H,Sato N,Tohyama M,Kamada T

更新日期：1990-06-01 00:00:00

abstract：:A randomized, double-blind comparison of lactose enemas plus placebo tablets vs. starch enemas plus neomycin tablets was performed on 18 patients with acute portal systemic encephalopathy. Ten patients received starch enemas (10%; 1000 ml t.i.d.) plus neomycin tablets and 8 patients received lactose enemas (20%; 1000 ...

journal_title：Gastroenterology

authors： Uribe M,Berthier JM,Lewis H,Mata JM,Sierra JG,García-Ramos G,Ramírez Acosta J,Dehesa M

更新日期：1981-07-01 00:00:00

abstract：:Plasma levels of gastrinlike, somatostatinlike, and cholecystokininlike immunoreactivity were determined by radioimmunoassay in peripheral blood from 11 beagles during pregnancy and in response to suckling during lactation. Cholecystokinin was determined in pooled and in individual plasma samples after separation of c...

journal_title：Gastroenterology

authors： Linden A,Eriksson M,Carlquist M,Uvnäs-Moberg K

更新日期：1987-03-01 00:00:00

abstract：:To define a potential role for the angiotensin system in Crohn's colitis, the colonic mucosal levels of angiotensin I and II were measured in endoscopic biopsy samples from patients with active Crohn's colitis (n = 20), ulcerative colitis (n = 13), other forms of colitis (n = 3), and normal controls (n = 17). Colonic ...

journal_title：Gastroenterology

authors： Jaszewski R,Tolia V,Ehrinpreis MN,Bodzin JH,Peleman RR,Korlipara R,Weinstock JV

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND & AIMS:The rate of 12alpha-hydroxylation of bile acid intermediates is believed to determine the ratio of cholic acid (CA) to chenodeoxycholic acid (CDCA) biosynthesis and the overall hydrophobicity of the bile acid pool. The aim of this study was to determine the effects of the level of expression of sterol...

journal_title：Gastroenterology

authors： Pandak WM,Bohdan P,Franklund C,Mallonee DH,Eggertsen G,Björkhem I,Gil G,Vlahcevic ZR,Hylemon PB

更新日期：2001-06-01 00:00:00

abstract：:The factors responsible for prevention of duodenal mucosal injury are not known. This series of experiments was performed to determine whether the human duodenum secretes bicarbonate that could prevent mucosal damage. To isolate a 4-cm segment of proximal (i.e., the duodenal bulb) or distal duodenum free of contaminat...

journal_title：Gastroenterology

authors： Isenberg JI,Hogan DL,Koss MA,Selling JA

更新日期：1986-08-01 00:00:00

abstract：:We have analyzed the frequency of chronicity and its distribution according to epidemiologic background following acute non-A, non-B hepatitis. Eighteen of 45 cases (40%) developed chronic liver disease. The incidence of chronicity was significantly higher following transfusion and among drug addicts (54% and 58%) tha...

journal_title：Gastroenterology

authors： Rakela J,Redeker AG

更新日期：1979-12-01 00:00:00

abstract：BACKGROUND & AIMS:Histamine-producing enterochromaffin-like (ECL) cells play an integrative role in the regulation of acid secretion. Decreased mucosal histamine concentrations and increased levels of interleukin (IL) 1 beta, IL-6, and IL-8 have been detected in the gastric mucosa inflamed with Helicobacter pylori. The...

journal_title：Gastroenterology

authors： Prinz C,Neumayer N,Mahr S,Classen M,Schepp W

更新日期：1997-02-01 00:00:00

abstract：:A patient with gastric outlet syndrome (Bouveret's syndrome) caused by a large gallstone impacted in the duodenal bulb was successfully treated by extracorporeal shock-wave lithotripsy. Thus, open abdominal surgery could be avoided. For disintegration of the stone, three consecutive lithotripsy procedures were necessa...

journal_title：Gastroenterology

authors： Holl J,Sackmann M,Hoffmann R,Schüssler P,Sauerbruch T,Jüngst D,Paumgartner G

更新日期：1989-08-01 00:00:00

abstract：BACKGROUND AND AIMS:The MDR1 gene encodes P-glycoprotein 170, an efflux transporter that is highly expressed in intestinal epithelial cells. The MDR1 exonic single nucleotide polymorphisms (SNPs) C3435T and G2677T have been shown to correlate with activity/expression of P-glycoprotein 170. METHODS:This was a case-cont...

journal_title：Gastroenterology

authors： Ho GT,Nimmo ER,Tenesa A,Fennell J,Drummond H,Mowat C,Arnott ID,Satsangi J

更新日期：2005-02-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma is a devastating disease, and patient outcomes have not improved in decades. Treatments that target tumor cells have largely failed. This could be because research has focused on cancer cells and the influence of the stroma on tumor progression has been largely ignored. The focus of pa...

journal_title：Gastroenterology

authors： Apte MV,Wilson JS,Lugea A,Pandol SJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND & AIMS:Dkk1 is a secreted antagonist of the Wnt/β-catenin signaling pathway. It is induced by inflammatory cytokines during colitis and exacerbates tissue damage by promoting apoptosis of epithelial cells. However, little is known about the physiologic role of Dkk1 in normal intestinal homeostasis and during...

journal_title：Gastroenterology

authors： Koch S,Nava P,Addis C,Kim W,Denning TL,Li L,Parkos CA,Nusrat A

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND & AIMS:Activated pancreatic stellate cells have recently been implicated in pancreatic fibrogenesis. This study examined the role of pancreatic stellate cells in alcoholic pancreatic fibrosis by determining whether these cells are activated by ethanol itself and, if so, whether such activation is caused by t...

journal_title：Gastroenterology

authors： Apte MV,Phillips PA,Fahmy RG,Darby SJ,Rodgers SC,McCaughan GW,Korsten MA,Pirola RC,Naidoo D,Wilson JS

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND & AIMS:The effects of leukotriene (LT) D(4) on intestinal epithelial cells govern events that are involved in cell survival and colon cancer, notably increased expression of cyclooxygenase (COX)-2 and enhanced production of prostaglandin E(2). We investigated possible correlations between distribution of the...

journal_title：Gastroenterology

authors： Ohd JF,Nielsen CK,Campbell J,Landberg G,Löfberg H,Sjölander A

更新日期：2003-01-01 00:00:00

abstract：:To look for possible HLA linkage in familial Crohn's disease, HLA haplotype segregation patterns were determined in 70 members of five kindreds, each having 2 or more patients with Crohn's disease (total number: 13 with Crohn's disease, 1 with ulcerative colitis). Concordant segregation of HLA haplotypes and disease w...

journal_title：Gastroenterology

authors： Eade OE,Moulton C,MacPherson BR,Andre-Ukena SS,Albertini RJ,Beeken WL

更新日期：1980-08-01 00:00:00

abstract：BACKGROUND & AIMS:In the absence of pathognomonic markers for Crohn's disease (CD) and ulcerative colitis (UC), the diagnosis of inflammatory bowel disease depends on a compendium of clinical, radiographic, endoscopic, and histologic criteria that bears imperfect specificity to the individual disorders. In 10% of cases...

journal_title：Gastroenterology

authors： Joossens S,Reinisch W,Vermeire S,Sendid B,Poulain D,Peeters M,Geboes K,Bossuyt X,Vandewalle P,Oberhuber G,Vogelsang H,Rutgeerts P,Colombel JF

更新日期：2002-05-01 00:00:00