Control of ascites absorption in anesthetized cats: effects of intraperitoneal pressure, protein, and furosemide diuresis.

abstract：BACKGROUND & AIMS:Intercellular communication through gap junctions has been proposed to be an important mechanism for the maintenance of tissue homeostasis. However, few studies have considered the role of gap junctions in gastric mucosa. The purpose of this study was to evaluate the distribution of gap junction-speci...

journal_title：Gastroenterology

authors： Uchida Y,Matsuda K,Sasahara K,Kawabata H,Nishioka M

更新日期：1995-11-01 00:00:00

abstract：:Endoscopic screening in 123 patients with pernicious anemia (PA) yielded 4 patients with solitary and 1 patient with multiple gastric carcinoid tumors. Quantitative histologic studies of multiple standardized biopsy specimens showed a significantly increased number of fundic mucosal argyrophil endocrine cells in 40 pa...

journal_title：Gastroenterology

authors： Borch K,Renvall H,Liedberg G

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND & AIMS:This longitudinal study investigated the interactions and roles of hepatitis B virus (HBV) genotypes, pre-S deletions, and core promoter and precore mutations on the progression of liver disease in hepatitis B e antigen (HBeAg)-negative patients. METHODS:A total of 141 HBeAg-negative patients without...

journal_title：Gastroenterology

authors： Chen CH,Hung CH,Lee CM,Hu TH,Wang JH,Wang JC,Lu SN,Changchien CS

更新日期：2007-11-01 00:00:00

abstract：:We studied the response of lymphocytes from 43 patients with inflammatory bowel disease to allogeneic stimulation in one-way mixed-lymphocyte cultures. We found that 53% of patients with inflammatory bowel disease, in contrast to 4% of normal and disease controls, had significant depression of mixed-lymphocyte culture...

journal_title：Gastroenterology

authors： Fiske SC,Falchuk ZM

更新日期：1980-10-01 00:00:00

abstract：BACKGROUND:Actin is a key contractile protein associated with the normal differentiation and function of gastrointestinal smooth muscle cells. Distinct changes in gastrointestinal smooth muscle cell morphology and function have been reported for the aganglionic rectum and megacolon of the adult lethal spotted mouse. Th...

journal_title：Gastroenterology

authors： Liddell RA,Mooers SU,Siegman MJ,McHugh KM

更新日期：1993-08-01 00:00:00

abstract：:A novel water-soluble dopamine-2 antagonist, N-[4-[2-(dimethylamino) ethoxy]benzyl]-3,4-dimethoxybenzamide hydrochloride (HSR-803) was synthesized and assayed for its gastrointestinal smooth muscle stimulating activity in vivo and in vitro. In the in vivo study, gastrointestinal contractile activity was measured by me...

journal_title：Gastroenterology

authors： Iwanaga Y,Miyashita N,Morikawa K,Mizumoto A,Kondo Y,Itoh Z

更新日期：1990-08-01 00:00:00

abstract：:Colonic and intestinal alkaline phosphatase were studied histoenzymatically and biochemically in normal mucosae from eight hemicolectomy specimens. Histochemically, the most intense reaction was found in the small intestine, followed by vascular endothelium and colonic epithelium, respectively. The reaction was strong...

journal_title：Gastroenterology

authors： Lev R,Griffiths WC

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Fiber and water-holding agents are used for the treatment of constipation. In what may appear to be a paradox, they are sometimes also used for the treatment of diarrhea; it has been proposed that they sequester water from liquid stools and/or increase the ratio of fecal solids to fecal water and thereby imp...

journal_title：Gastroenterology

authors： Eherer AJ,Santa Ana CA,Porter J,Fordtran JS

更新日期：1993-04-01 00:00:00

abstract：:A new model of an acute bleeding gastric ulcer with a single bleeding artery in its base has been developed. A suction ulcer defect is created over a large, submucosal artery. Small bleeding marginal vessels are electrocoagulated with a fine-tipped bipolar forceps. The artery in the base of the ulcer is dissected free...

journal_title：Gastroenterology

authors： Dennis MB,Silverstein FE,Gilbert DA,Peoples JE

更新日期：1981-06-01 00:00:00

abstract：:Specimens of the sigmoid colon were obtained from male and female patients (n = 11) with carcinoma of the colon or rectum and studied immunohistochemically for vasoactive intestinal polypeptide-, somatostatin-, substance P-, neuropeptide Y-, calcitonin gene-related peptide-, met- and leu-enkephalin-, 5-hydroxytryptami...

journal_title：Gastroenterology

authors： Crowe R,Kamm MA,Burnstock G,Lennard-Jones JE

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND & AIMS:Entecavir (ETV) and tenofovir disoproxil fumarate (TDF) are potent antiviral agents that might have additive or synergistic antiviral activity in treatment of patients with chronic hepatitis B (CHB). We compared the efficacy and safety of ETV monotherapy with those of a combination of ETV and TDF. ME...

journal_title：Gastroenterology

authors： Lok AS,Trinh H,Carosi G,Akarca US,Gadano A,Habersetzer F,Sievert W,Wong D,Lovegren M,Cohen D,Llamoso C

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND & AIMS:Hereditary colorectal cancer is associated most commonly with the hereditary nonpolyposis colorectal cancer or familial adenomatous polyposis syndromes. We investigated the prevalence of early onset colorectal cancer and the frequency of p53 germline mutations in 64 families from a Li-Fraumeni syndrom...

journal_title：Gastroenterology

authors： Wong P,Verselis SJ,Garber JE,Schneider K,DiGianni L,Stockwell DH,Li FP,Syngal S

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND & AIMS:Alcohol abuse causes half of all deaths from cirrhosis in the West, but few tools are available for noninvasive diagnosis of alcoholic liver disease. We evaluated 2 elastography techniques for diagnosis of alcoholic fibrosis and cirrhosis; liver biopsy with Ishak score and collagen-proportionate area ...

journal_title：Gastroenterology

authors： Thiele M,Detlefsen S,Sevelsted Møller L,Madsen BS,Fuglsang Hansen J,Fialla AD,Trebicka J,Krag A

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND & AIMS:Fecal incontinence (FI) is characterized by uncontrolled passage of solid or liquid stool. We aimed to determine the prevalence and severity of FI in a large sample of US residents. METHODS:We recruited a representative sample of patients in October 2015 to complete the National Gastrointestinal (GI)...

journal_title：Gastroenterology

authors： Menees SB,Almario CV,Spiegel BMR,Chey WD

更新日期：2018-05-01 00:00:00

abstract：:The effects of calcium channel blockers on water transport in the rat ileum and distal colon were studied in vivo using the single-pass perfusion technique. Parenteral but not intraluminal verapamil, and parenteral nifedipine increased ileal water absorption, with effects lasting at least 60 min. In contrast, i.p. ver...

journal_title：Gastroenterology

authors： Donowitz M,Levin S,Powers G,Elta G,Cohen P,Cheng H

更新日期：1985-10-01 00:00:00

abstract：:In order to discover the effect of bile acid synthesis on cholesterol secretion into the bile, 7 rhesus monkeys were studied at various stable interruptions of the enterohepatic circulation of bile acids. In 4 animals, 2.5 and 7.5% interruptions were compared; 2.5 and 15% interruptions were compared in 5 animals. Ther...

journal_title：Gastroenterology

authors： Strasberg SM,Petrunka CN,Ilson RG

更新日期：1976-12-01 00:00:00

abstract：:Spontaneous remission of gastric acid hypersecretion in the Zollinger-Ellison syndrome occurs rarely. This study shows the development of gastric secretory mucosal atrophy resulting in achlorhydria and loss of pepsin secretion in a 63-year-old woman with the Zollinger-Ellison syndrome. Reduced secretion began soon aft...

journal_title：Gastroenterology

authors： Griffith JL,Cummings OW,Hirschowitz BI

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND & AIMS:The peroxisome proliferator-activated receptor delta (PPARD) regulates cell metabolism, proliferation, and inflammation and has been associated with gastric and other cancers. Villin-positive epithelial cells are a small population of quiescent gastric progenitor cells. We expressed PPARD from a villi...

journal_title：Gastroenterology

authors： Zuo X,Deguchi Y,Xu W,Liu Y,Li HS,Wei D,Tian R,Chen W,Xu M,Yang Y,Gao S,Jaoude JC,Liu F,Chrieki SP,Moussalli MJ,Gagea M,Sebastian MM,Zheng X,Tan D,Broaddus R,Wang J,Ajami NJ,Swennes AG,Watowich SS,Shureiqi

更新日期：2019-07-01 00:00:00

abstract：:We have analyzed the frequency of chronicity and its distribution according to epidemiologic background following acute non-A, non-B hepatitis. Eighteen of 45 cases (40%) developed chronic liver disease. The incidence of chronicity was significantly higher following transfusion and among drug addicts (54% and 58%) tha...

journal_title：Gastroenterology

authors： Rakela J,Redeker AG

更新日期：1979-12-01 00:00:00

abstract：:This study correlates duodenal bile acid delivery with motility of the sphincter of Oddi during the fasting state. Dogs were prepared with a functional cholecystectomy, a duodenal cannula for direct vision cannulation of the common bile duct, and 12 bipolar electrodes serosally implanted from stomach to terminal ileum...

journal_title：Gastroenterology

authors： Scott RB,Strasberg SM,El-Sharkawy TY,Diamant NE

更新日期：1984-10-01 00:00:00

abstract：:The human gastrointestinal tract contains distinct microbial communities that differ in composition and function based on their location, as well as age, sex, race/ethnicity, and diet of their host. We describe the bacterial taxa present in different locations of the GI tract, and their specific metabolic features. Th...

journal_title：Gastroenterology

authors： Hollister EB,Gao C,Versalovic J

更新日期：2014-05-01 00:00:00

abstract：:The presence of receptors for insulinlike growth factor I and II in human colonic epithelium is demonstrated. Scatchard analysis of binding data obtained with 125I-insulinlike growth factor I showed an insulinlike growth factor I receptor with a dissociation constant of 8.6 nM and a binding capacity of 0.8 pmol/mg mem...

journal_title：Gastroenterology

authors： Rouyer-Fessard C,Gammeltoft S,Laburthe M

更新日期：1990-03-01 00:00:00

abstract：:Increased type III collagen deposition in all layers of the intestinal tract, including the lamina propria, is a common feature of strictures in Crohn's disease. In the present study, it was found that in comparison with fibroblasts from normal or nonstrictured but inflamed intestinal lamina propria, the fibroblasts i...

journal_title：Gastroenterology

authors： Stallmach A,Schuppan D,Riese HH,Matthes H,Riecken EO

更新日期：1992-06-01 00:00:00

abstract：BACKGROUND & AIMS:The complications of diverticulosis cause considerable morbidity in the United States; health care expenditures for this disorder are estimated to be $2.5 billion per year. Many physicians and patients believe that a high-fiber diet and frequent bowel movements prevent the development of diverticulosi...

journal_title：Gastroenterology

authors： Peery AF,Barrett PR,Park D,Rogers AJ,Galanko JA,Martin CF,Sandler RS

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND & AIMS:One approach to the development of targeted cancer chemotherapy exploits increased uptake of the agent into neoplastic cells. In this scenario, higher concentrations of the agent in cancer cells are responsible for differential killing, whereas the low concentration in normal human cells decreases sid...

journal_title：Gastroenterology

authors： Abe T,Unno M,Onogawa T,Tokui T,Kondo TN,Nakagomi R,Adachi H,Fujiwara K,Okabe M,Suzuki T,Nunoki K,Sato E,Kakyo M,Nishio T,Sugita J,Asano N,Tanemoto M,Seki M,Date F,Ono K,Kondo Y,Shiiba K,Suzuki M,Ohtani H,S

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND/AIMS:Platelet-activating factor (PAF) is involved in the pathophysiology of motility changes induced by intestinal inflammation. The aim of this study was to evaluate a possible desensitization of PAF receptors in guinea pig intestinal smooth muscle cells after experimental inflammation induced by trinitrobe...

journal_title：Gastroenterology

authors： Jeanneton O,Delvaux M,Frexinos J,Bueno L

更新日期：1995-06-01 00:00:00

abstract：:This study examines the effects of endotoxin on intestinal water and electrolyte transport in adult male rats. Endotoxin (1.55 mg/kg, intravenously) reduced in vivo colonic saline absorption 61% in 1 hour. In vitro unidirectional and net 22Na and 36Cl fluxes showed that endotoxin significantly decreased net colonic 22...

journal_title：Gastroenterology

authors： Ciancio MJ,Vitiritti L,Dhar A,Chang EB

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND & AIMS:Impaired gallbladder emptying occurs in patients undergoing bile salt therapy for cholesterol gallstone dissolution and in patients with cirrhosis who have elevated serum bile salt concentrations. To determine if bile salts directly inhibit gallbladder contractility, isometric contraction of the guine...

journal_title：Gastroenterology

authors： Xu QW,Freedman SM,Shaffer EA

更新日期：1997-05-01 00:00:00

abstract：:Erythromycin has been shown to act as a motilin agonist by binding to motilin receptors on gastrointestinal smooth muscle and to improve the severely impaired gastric emptying in patients with diabetic gastroparesis. To elucidate the motor pattern that accounts for this accelerated emptying, the effect of 200 mg eryth...

journal_title：Gastroenterology

authors： Annese V,Janssens J,Vantrappen G,Tack J,Peeters TL,Willemse P,Van Cutsem E

更新日期：1992-03-01 00:00:00

abstract：BACKGROUND & AIMS:Activating transcription factor 4 (ATF4) regulates genes involved in the inflammatory response, amino acid metabolism, autophagy, and endoplasmic reticulum stress. We investigated whether its activity is altered in patients with inflammatory bowel diseases (IBDs) and mice with enterocolitis. METHODS:...

journal_title：Gastroenterology

authors： Hu X,Deng J,Yu T,Chen S,Ge Y,Zhou Z,Guo Y,Ying H,Zhai Q,Chen Y,Yuan F,Niu Y,Shu W,Chen H,Ma C,Liu Z,Guo F

更新日期：2019-03-01 00:00:00