Chronic liver disease after acute non-A, non-B viral hepatitis.

abstract：:Focal nodular hyperplasia (FNH) and hepatocellular adenoma (HCA) are benign hepatocellular tumors that develop most frequently in women without cirrhosis. Genomic approaches have identified signaling pathways related to these benign hepatocyte proliferations. FNH, a polyclonal lesion, is characterized by local vascula...

journal_title：Gastroenterology

authors： Nault JC,Bioulac-Sage P,Zucman-Rossi J

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND & AIMS:We have previously shown that patients with irritable bowel syndrome (IBS) have impaired transit of intestinal gas loads. Because abnormal gas retention can be experimentally reproduced in healthy subjects by pharmacological inhibition of gut motility, we hypothesized that impaired gas transit and ret...

journal_title：Gastroenterology

authors： Caldarella MP,Serra J,Azpiroz F,Malagelada JR

更新日期：2002-06-01 00:00:00

abstract：BACKGROUND & AIMS:Prostacyclin and nitric oxide have been involved in the hyperkinetic syndrome in portal hypertension. The aim of this study was to investigate the relative contribution and possible interaction between prostacyclin and NO in this circulatory abnormality. METHODS:Portal vein-ligated and sham-operated ...

journal_title：Gastroenterology

authors： Fernández M,García-Pagán JC,Casadevall M,Mourelle MI,Piqué JM,Bosch J,Rodés J

更新日期：1996-05-01 00:00:00

abstract：:Twenty-two patients with Zollinger-Ellison syndrome were managed by a combined medical and surgical approach. Patients were treated initially with cimetidine or ranitidine. A laparotomy was performed to remove easily resectable tumors and to carry out a proximal gastric vagotomy. Tumors were found in 9 patients (41%) ...

journal_title：Gastroenterology

authors： Richardson CT,Peters MN,Feldman M,McClelland RN,Walsh JH,Cooper KA,Willeford G,Dickerman RM,Fordtran JS

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND/AIMS:The pathways underlying rectal hypersensitivity to balloon distention in patients with irritable bowel syndrome (IBS) are not known. The aim of this study was to characterize the involvement of sacral and thoracolumbar afferents in the perception of rectal distention. METHODS:Rectal balloon distention ...

journal_title：Gastroenterology

authors： Lembo T,Munakata J,Mertz H,Niazi N,Kodner A,Nikas V,Mayer EA

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND & AIMS:Amidated gastrins are acid secretagogues and growth factors. Their precursor, progastrin, is a growth factor but not a secretagogue. Cleavage of progastrin at Arg94/95 determines the expression of these two alternative patterns of biological activity. We examined the hypothesis that cleavage at Arg94/...

journal_title：Gastroenterology

authors： Bishop L,Dimaline R,Blackmore C,Deavall D,Dockray GJ,Varro A

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND & AIMS:Early embryogenesis involves cell fate decisions that define the body axes and establish pools of progenitor cells. Development does not stop once lineages are specified; cells continue to undergo specific maturation events, and changes in gene expression patterns lead to their unique physiological fu...

journal_title：Gastroenterology

authors： Direnzo D,Hess DA,Damsz B,Hallett JE,Marshall B,Goswami C,Liu Y,Deering T,Macdonald RJ,Konieczny SF

更新日期：2012-08-01 00:00:00

abstract：:The role of capsaicin-sensitive afferent neurons in acid-induced HCO3- secretion was investigated in the duodenum of anesthetized rats. The proximal duodenum was perfused with saline (pH 4.5), the pH of perfusate and the transmucosal potential differences were continuously monitored, and HCO3- output was determined by...

journal_title：Gastroenterology

authors： Takeuchi K,Matsumoto J,Ueshima K,Okabe S

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:Liver injury in many patients with chronic hepatitis B is sporadic and is often characterized by acute exacerbations alternating with relatively normal liver function. The aim of this study was to perform detailed serological and biochemical analysis during periods of active liver disease to better understan...

journal_title：Gastroenterology

authors： Maruyama T,Iino S,Koike K,Yasuda K,Milich DR

更新日期：1993-10-01 00:00:00

abstract：:The results of balloon dilatation of upper digestive tract stricture in 111 patients were evaluated. Eighty-eight patients had esophageal strictures and 23 had gastric or pyloric strictures. Thirty-six patients had strictures associated with previous operations. Twenty-two percent of the patients with esophageal stric...

journal_title：Gastroenterology

authors： Lindor KD,Ott BJ,Hughes RW Jr

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND & AIMS:Epithelial cells of the small intestine migrate to the tip of the villus at which they are shed. It is not understood how the intestinal barrier is maintained during this high cell turnover. The aim of this study was to use high-resolution in vivo light microscopy to investigate the mechanism of epith...

journal_title：Gastroenterology

authors： Watson AJ,Chu S,Sieck L,Gerasimenko O,Bullen T,Campbell F,McKenna M,Rose T,Montrose MH

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND & AIMS:Exposure to biologic and immunosuppressant agents during breastfeeding is controversial, and there are limited data on safety. We investigated whether biologics are detectable in breast milk from women receiving treatment for inflammatory bowel diseases (IBDs) and whether breastfeeding while receiving...

journal_title：Gastroenterology

authors： Matro R,Martin CF,Wolf D,Shah SA,Mahadevan U

更新日期：2018-09-01 00:00:00

abstract：:This study was undertaken to try to solve the controversy about the influence of gastrointestinal contents on the genesis of bowel sounds, and to probe the respective importance of the various abdominal viscera. Eleven healthy volunteers were intubated by mouth with a multiple-lumen tube. Bowel sounds were recorded fo...

journal_title：Gastroenterology

authors： Politzer JP,Devroede G,Vasseur C,Gerard J,Thibault R

更新日期：1976-08-01 00:00:00

abstract：:The aims of our prospective study were to determine the development and natural history of esophageal varices and variceal bleeding in patients with primary biliary cirrhosis. As part of a controlled clinical study, 265 patients with primary biliary cirrhosis who did not have esophageal varices at entry were followed ...

journal_title：Gastroenterology

authors： Gores GJ,Wiesner RH,Dickson ER,Zinsmeister AR,Jorgensen RA,Langworthy A

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND & AIMS:Chronic stress is associated with visceral hyperalgesia in functional gastrointestinal disorders. We investigated whether corticosterone plays a role in chronic psychological stress-induced visceral hyperalgesia. METHODS:Male rats were subjected to 1-hour water avoidance (WA) stress or subcutaneous c...

journal_title：Gastroenterology

authors： Hong S,Zheng G,Wu X,Snider NT,Owyang C,Wiley JW

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND & AIMS:Cholecystokinin (CCK) is a satiation peptide released during meals in response to lipid intake; it regulates pancreatic digestive enzymes that are required for absorption of nutrients. We proposed that mice with a disruption in the CCK gene (CCK knockout [CCK-KO] mice) that were fed a diet of 20% butt...

journal_title：Gastroenterology

authors： Lo CM,King A,Samuelson LC,Kindel TL,Rider T,Jandacek RJ,Raybould HE,Woods SC,Tso P

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND & AIMS:Leptin production has been reported in the rat and in human stomach. It initiates intestinal nutrient absorption. In this study, we analyzed the effect of vagal stimulation on leptin release in the human stomach. METHODS:We studied the secretion of gastric acid and leptin on stimulation with insulin ...

journal_title：Gastroenterology

authors： Sobhani I,Buyse M,Goïot H,Weber N,Laigneau JP,Henin D,Soul JC,Bado A

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND AND AIMS:Earlier studies have suggested that patients with hemochromatosis have poor post-transplantation survival. We aimed to compare patients with hemochromatosis to those with other causes of liver disease with regard to post-transplantation survival. METHODS:We compared the post-transplant survival of ...

journal_title：Gastroenterology

authors： Yu L,Ioannou GN

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND & AIMS:In patients with achalasia esophagus, swallows induce simultaneous pressure waves known as esophageal pressurization. We studied the mechanism of esophageal pressurization and bolus flow patterns in patients with type 2 or type 3 achalasia. METHODS:We recorded high-resolution manometry with impedance...

journal_title：Gastroenterology

authors： Park S,Zifan A,Kumar D,Mittal RK

更新日期：2018-08-01 00:00:00

abstract：:A case of spontaneous rupture of a nonparasitic liver cyst, documented by serial computed tomography scans, is reported. The patient was closely followed clinically after the rupture of the cyst and was treated conservatively, without surgical intervention. No peritonitis developed. This unusual complication of nonpar...

journal_title：Gastroenterology

authors： Akriviadis EA,Steindel H,Ralls P,Redeker AG

更新日期：1989-07-01 00:00:00

abstract：:Antral ulcers were produced in unanesthetized rats in 3 hr by simultaneous intravenous administration of acetylsalicylic acid (ASA) and gastric perfusion with 0.15 M HCl. Intravenous infusion of ASA alone or gastric perfusion with HCl alone produced no antral ulcers. Plasma salicylate levels ranged from 250 to 350 mic...

journal_title：Gastroenterology

authors： Kauffman GL Jr,Grossman MI

更新日期：1978-12-01 00:00:00

abstract：:In neurogenic fecal incontinence there is denervation of the external anal sphincter and pelvic floor muscles but the role of the internal anal sphincter is incompletely understood. We have evaluated the internal anal sphincter in 6 patients with neurogenic incontinence undergoing postanal repair and in 7 control subj...

journal_title：Gastroenterology

authors： Lubowski DZ,Nicholls RJ,Burleigh DE,Swash M

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND & AIMS:Prophylactic administration of interleukin (IL)-10 decreases the severity of experimental pancreatitis. Prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis in humans is a unique model to study the potential role of IL-10 in this setting. METHODS:In a single-center, d...

journal_title：Gastroenterology

authors： Devière J,Le Moine O,Van Laethem JL,Eisendrath P,Ghilain A,Severs N,Cohard M

更新日期：2001-02-01 00:00:00

abstract：:The efficacy of various adsorbents for endotoxin was tested in vitro and in vivo using a murine experimental model of gut-derived endotoxemia. A quantitative limulus amebocyte lysate microtiter test and the limulus amebocyte lysate tube test were used to determine intestinal and circulating levels of endotoxin. Kaopec...

journal_title：Gastroenterology

authors： Ditter B,Urbaschek R,Urbaschek B

更新日期：1983-06-01 00:00:00

abstract：:The present study was undertaken to evaluate the ability of human hepatocytes to respond in culture to various mitotic agents including epidermal growth factor (EGF), transforming growth factor alpha (TGF-alpha), or serum from patients with fulminant hepatitis. Human hepatocytes were maintained in culture on collagen-...

journal_title：Gastroenterology

authors： Blanc P,Etienne H,Daujat M,Fabre I,Zindy F,Domergue J,Astre C,Saint Aubert B,Michel H,Maurel P

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND & AIMS:Biliary epithelial cells are the target of numerous immune-mediated liver diseases, yet their role in pathogenesis remains unclear because of difficulties in obtaining pure preparations. The aim of this study was to establish pure clones of immortalized murine intrahepatic biliary epithelial cells. M...

journal_title：Gastroenterology

authors： Paradis K,Le ON,Russo P,St-Cyr M,Fournier H,Bu D

更新日期：1995-10-01 00:00:00

abstract：:The bioavailability of parenteral cimetidine was tested in 12 volunteers in a balanced three-way crossover study. Blood levels and urinary excretion were compared after intramuscular and intravenous injection and oral administration of 300 mg of cinetidine. The results indicated that the intramuscular and intravenous ...

journal_title：Gastroenterology

authors： Walkenstein SS,Dubb JW,Randolph WC,Westlake WJ,Stote RM,Intoccia AP

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND & AIMS:Although restorative proctocolectomy with ileal pouch-anal anastomosis (IPAA) substantially reduces the risk of colorectal cancer in patients with inflammatory bowel disease (IBD), subsequent pouch neoplasia can develop. There are few data on the incidence of and risk factors for neoplasia, so there i...

journal_title：Gastroenterology

authors： Derikx LA,Kievit W,Drenth JP,de Jong DJ,Ponsioen CY,Oldenburg B,van der Meulen-de Jong AE,Dijkstra G,Grubben MJ,van Laarhoven CJ,Nagtegaal ID,Hoentjen F,Dutch Initiative on Crohn and Colitis.

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND & AIMS:There is controversy over the optimal management strategy for patients with acute pancreatitis (AP). Studies have shown a hospital volume benefit for in-hospital mortality after surgery, and we examined whether a similar mortality benefit exists for patients admitted with AP. METHODS:Using the Nation...

journal_title：Gastroenterology

authors： Singla A,Simons J,Li Y,Csikesz NG,Ng SC,Tseng JF,Shah SA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND & AIMS:Approximately 10% of children on the liver transplant wait-list in the United States die every year. We examined deceased donor liver offer acceptance patterns and their contribution to pediatric wait-list mortality. METHODS:We performed a retrospective cohort study of children on the US liver transp...

journal_title：Gastroenterology

authors： Hsu EK,Shaffer ML,Gao L,Sonnenday C,Volk ML,Bucuvalas J,Lai JC

更新日期：2017-10-01 00:00:00