Interleukin 10 reduces the incidence of pancreatitis after therapeutic endoscopic retrograde cholangiopancreatography.

abstract：:Helicobacter pylori has recently been implicated as an etiologic agent of gastroduodenal disorders. Comparing the antibody to H. pylori in the sera of patients with that of normal controls by Western blot analysis, a unique antibody was detected in the sera of patients, which reacted with the 25-kilodalton antigen of ...

journal_title：Gastroenterology

authors： Sugiyama T,Imai K,Yoshida H,Takayama Y,Yabana T,Yokota K,Oguma K,Yachi A

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND/AIMS:The frequency of colorectal adenomas, the precursor lesions for most cases of colorectal carcinoma, has been generally measured as prevalence rates of adenomas at autopsy or colonoscopy. The aim of this study was to estimate the incidence rate of adenomas and compare it with the adenoma recurrence rate....

journal_title：Gastroenterology

authors： Neugut AI,Jacobson JS,Ahsan H,Santos J,Garbowski GC,Forde KA,Treat MR,Waye J

更新日期：1995-02-01 00:00:00

abstract：:Medical and recreational cannabis use has increased dramatically over the last decade, resulting from mainstream cultural acceptance and legalization in several countries worldwide. Cannabis and its derivatives affect many gastrointestinal processes via the endocannabinoid system (ECS). The ECS influences gastrointest...

journal_title：Gastroenterology

authors： Gotfried J,Naftali T,Schey R

更新日期：2020-07-01 00:00:00

abstract：:The effects of IV injection of 5-hydroxytryptamine 3 receptor antagonists (BRL 43694 and GR38032F) on gastrointestinal contractile activity were studied in dogs with vagally denervated fundic pouch in the conscious state by means of chronically implanted force transducers in the gastrointestinal tract and the pouch. I...

journal_title：Gastroenterology

authors： Itoh Z,Mizumoto A,Iwanaga Y,Yoshida N,Torii K,Wakabayashi K

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND & AIMS:HCV nonstructural protein 5A (NS5A) has been implicated in regulating cell growth and interferon response. The NS5A protein contains proline-rich regions that are highly conserved among HCV genotypes and match Src homology 3 (SH3)-binding motifs (PxxP) found in various cellular signaling molecules. M...

journal_title：Gastroenterology

authors： Nanda SK,Herion D,Liang TJ

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND & AIMS:In 1988, we reported the first twin study in inflammatory bowel disease. The aim of the current study was to follow up these twins regarding new cases of inflammatory bowel disease and Crohn's disease characteristics using the Vienna classification. METHODS:The official Swedish population register an...

journal_title：Gastroenterology

authors： Halfvarson J,Bodin L,Tysk C,Lindberg E,Järnerot G

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND/AIMS:Hepatic osmoreceptors are sensitive to changes in portal blood osmolality and cause variations in plasma antidiuretic hormone and water diuresis, which prevent major systemic osmotic changes. Insensitivity of hepatic osmoreceptors might contribute to maintaining increased plasma levels of antidiuretic h...

journal_title：Gastroenterology

authors： Castellano G,Solis-Herruzo JA,Gonzalez A,Morillas JD,Moreno D,Muñoz T,Larrodera L

更新日期：1994-03-01 00:00:00

abstract：:In rats fasted 4 days, immunoreactive gastrin concentrations decreased to one-third of the fed levels in antral tissue and to one-eight of the fed levels in serum. The number of antral cells that reacted with fluorescent antigastrin antiserum was also correspondingly decreased. After refeeding, serum gastrin returned ...

journal_title：Gastroenterology

authors： Lichtenberger LM,Lechago J,Johnson LR

更新日期：1975-06-01 00:00:00

abstract：BACKGROUND & AIMS:There is controversy over the optimal management strategy for patients with acute pancreatitis (AP). Studies have shown a hospital volume benefit for in-hospital mortality after surgery, and we examined whether a similar mortality benefit exists for patients admitted with AP. METHODS:Using the Nation...

journal_title：Gastroenterology

authors： Singla A,Simons J,Li Y,Csikesz NG,Ng SC,Tseng JF,Shah SA

更新日期：2009-12-01 00:00:00

abstract：:Nonalcoholic fatty liver disease (NAFLD) is one of the main chronic noncommunicable diseases in Westernized societies; its worldwide prevalence has doubled during the last 20 years. NAFLD has serious health implications not only for adults, but also for children. However, pediatric NAFLD is not only an important globa...

journal_title：Gastroenterology

authors： Nobili V,Alisi A,Newton KP,Schwimmer JB

更新日期：2016-06-01 00:00:00

abstract：BACKGROUND & AIMS:In searching for effects of acetaminophen (APAP) on hepatocytes downstream of its metabolism that may participate in hepatotoxicity, we examined the role of stress kinases. METHODS:Mouse hepatocytes and C57BL/6 mice were administered a toxic dose of APAP with or without SP600125, a chemical c-jun N-t...

journal_title：Gastroenterology

authors： Gunawan BK,Liu ZX,Han D,Hanawa N,Gaarde WA,Kaplowitz N

更新日期：2006-07-01 00:00:00

abstract：:Peptic digestion of gluten results in the production of substances having opiatelike activity in bio- and receptor assays. These substances have been termed exorphins. In this study, we determined the effect of gluten, hydrolyzed gluten, and hydrolyzed gluten plus the opiate blocker naloxone on a variety of hormonal p...

journal_title：Gastroenterology

authors： Morley JE,Levine AS,Yamada T,Gebhard RL,Prigge WF,Shafer RB,Goetz FC,Silvis SE

更新日期：1983-06-01 00:00:00

abstract：:The conventional method of ascitic fluid culture detects bacteria in only 42%-65% of patients who have neutrocytic ascites and suspected spontaneous bacterial peritonitis. In this study ascitic fluid was cultured by the conventional method as well as by a new method consisting of bedside inoculation of blood culture b...

journal_title：Gastroenterology

authors： Runyon BA,Canawati HN,Akriviadis EA

更新日期：1988-11-01 00:00:00

abstract：:Several compounds, in particular bile acids, undergo enterohepatic circulation (EHC). Limited data are available on the pathophysiologic aspects of this circulation. In the present study we describe a surgical technique in rats that allows a long-term, reversible interruption of the EHC and monitoring of peripheral bl...

journal_title：Gastroenterology

authors： Kuipers F,Havinga R,Bosschieter H,Toorop GP,Hindriks FR,Vonk RJ

更新日期：1985-02-01 00:00:00

abstract：:In this review, we speculate about future therapeutic approaches for inflammatory bowel diseases (IBDs), focusing on the need for better preclinical and clinical models and approaches beyond small molecules and systemically administered biologics. We offer ideas to change clinical trial programs and to use immunologic...

journal_title：Gastroenterology

authors： Plevy SE,Targan SR

更新日期：2011-05-01 00:00:00

abstract：BACKGROUND & AIMS:The transcription factor nuclear factor-κB (NF-κB) (a heterodimer of NF-κB1p50 and RelA) is activated rapidly in acute pancreatitis (AP). However, it is not clear whether NF-κB promotes or protects against AP. We used the NF-κB inhibitor protein, inhibitor of κB (IκB)α, to study the roles of NF-κB in ...

journal_title：Gastroenterology

authors： Neuhöfer P,Liang S,Einwächter H,Schwerdtfeger C,Wartmann T,Treiber M,Zhang H,Schulz HU,Dlubatz K,Lesina M,Diakopoulos KN,Wörmann S,Halangk W,Witt H,Schmid RM,Algül H

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND & AIMS:Patients affected by familial adenomatous polyposis (FAP) are at increased risk of developing duodenal adenomas. In this study, cell proliferation of duodenal mucosa was analyzed to detect kinetic abnormalities related to cancer risk. METHODS:Duodenal biopsy specimens were collected in three groups o...

journal_title：Gastroenterology

authors： Santucci R,Volpe L,Zannoni U,Paganelli GM,Poggi B,Calabrese C,Biasco G

更新日期：1997-10-01 00:00:00

abstract：:A rapid, sensitive, precise radioimmunoassay for conjugates of chenodeoxycholic (chenic) acid has been developed and validated. Immunogen was prepared with chenylglycine couples to bovine serum albumin, emulsified in Freund's complete adjuvant, and injected intracutaneously in rabbits. Antibodies of moderate titer (us...

journal_title：Gastroenterology

authors： Schalm SW,van Berge-Henegouwen GP,Hofmann AF,Cowen AE,Turcotte J

更新日期：1977-08-01 00:00:00

abstract：:We performed 92 computed tomography-guided percutaneous needle aspirations of pancreatic inflammatory masses in 60 patients suspected of harboring pancreatic infection. Thirty-six patients (60%) were found by Gram stain and culture to have a total of 41 separate episodes of pancreatic infection. Among 42 aspirates jud...

journal_title：Gastroenterology

authors： Gerzof SG,Banks PA,Robbins AH,Johnson WC,Spechler SJ,Wetzner SM,Snider JM,Langevin RE,Jay ME

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND & AIMS:Altered gut microbiota is implicated in development of colorectal cancer (CRC). Some intestinal bacteria have been reported to potentiate intestinal carcinogenesis by producing genotoxins, altering the immune response and intestinal microenvironment, and activating oncogenic signaling pathways. We inv...

journal_title：Gastroenterology

authors： Wong SH,Zhao L,Zhang X,Nakatsu G,Han J,Xu W,Xiao X,Kwong TNY,Tsoi H,Wu WKK,Zeng B,Chan FKL,Sung JJY,Wei H,Yu J

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND & AIMS:Monocytes/macrophages infiltrate into injured livers. We tried to clarify their roles in inflammation and subsequent fibrogenesis by inhibiting their infiltration with a mutated form (7ND; 7 amino acids at the N-terminal were deleted) of monocyte chemoattractant protein 1, which may function as a domi...

journal_title：Gastroenterology

authors： Imamura M,Ogawa T,Sasaguri Y,Chayama K,Ueno H

更新日期：2005-01-01 00:00:00

abstract：:Colchicine treatment was used in this randomized placebo-controlled trial in patients with severe acute alcoholic hepatitis [serum bilirubin greater than or equal to 5 mg/dL (85.5 mumol/L) mean, 17.5 +/- 7.5 mg/dL (299.25 +/- 128.25 mumol/L)]. Hospitalization mortality and morbidity and the effect on biochemical test ...

journal_title：Gastroenterology

authors： Akriviadis EA,Steindel H,Pinto PC,Fong TL,Kanel G,Reynolds TB,Gupta S

更新日期：1990-09-01 00:00:00

abstract：:The role of lipoxygenase metabolites in ethanol-induced gastric mucosal injury and submucosal microvascular change in the rat was studied by in vivo microscopy. Intragastric ethanol-instillation caused marked submucosal venular constriction, dilatation of small arterioles, and corpus mucosal gross lesion formation. Th...

journal_title：Gastroenterology

authors： Yonei Y,Guth PH

更新日期：1989-08-01 00:00:00

abstract：:The occurrence of inflammatory bowel disease in all three members of one family is described. Studies of white blood cell chromosomes, histocompatibility antigens, and cellular and humoral immunity failed to explain this unusual phenomenon. However, the appearance of inflammatory bowel disease in an entire family reem...

journal_title：Gastroenterology

authors： Rosenberg JL,Kraft SC,Kirsner JB

更新日期：1976-05-01 00:00:00

abstract：BACKGROUND/AIMS:Recent in vivo studies using proton magnetic resonance (1H-MR) spectroscopy showed low levels of myo-inositol in the brain in hepatic encephalopathy; the pathogenetic relevance of this observation is unclear. METHODS:Myo-inositol and glutamine levels in the brain were studied in vivo by 1H-MR spectrosc...

journal_title：Gastroenterology

authors： Häussinger D,Laubenberger J,vom Dahl S,Ernst T,Bayer S,Langer M,Gerok W,Hennig J

更新日期：1994-11-01 00:00:00

abstract：:Serial studies of plasma lipids and lipoproteins were performed in 4 patients with acute alcoholic liver disease characterized by a massive fatty liver and laboratory evidence of intrahepatic cholestasis. There were striking alterations in the plasma lipoprotein electrophoretic patterns characterized by the absence of...

journal_title：Gastroenterology

authors： Sabesin SM,Hawkins HL,Kuiken L,Ragland JB

更新日期：1977-03-01 00:00:00

abstract：:The efficacy of various adsorbents for endotoxin was tested in vitro and in vivo using a murine experimental model of gut-derived endotoxemia. A quantitative limulus amebocyte lysate microtiter test and the limulus amebocyte lysate tube test were used to determine intestinal and circulating levels of endotoxin. Kaopec...

journal_title：Gastroenterology

authors： Ditter B,Urbaschek R,Urbaschek B

更新日期：1983-06-01 00:00:00

abstract：:A 76-yr-old male presented with Guillain-Barré syndrome after acute hepatitis B virus infection. Main immunologic features were: (a) high levels of circulating hepatitis B surface antigen-containing immune complexes in serum and cerebrospinal fluid during the acute neurologic syndrome, and (b) clearance of immune-comp...

journal_title：Gastroenterology

authors： Penner E,Maida E,Mamoli B,Gangl A

更新日期：1982-03-01 00:00:00

abstract：:Gastrinomas were localized by concurrent blood sampling in the hepatic vein and portal vein tributaries in 10 of 12 Zollinger-Ellison patients. In one patient, the portal vein could not be catheterized; in the other, a gastrin gradient could not be picked up in either of two examinations. Six of the patients were subs...

journal_title：Gastroenterology

authors： Burcharth F,Stage JG,Stadil F,Jensen LI,Fischermann K

更新日期：1979-09-01 00:00:00

abstract：:Pancreatitis is a common disorder with significant morbidity and mortality, yet little is known about its pathogenesis, and there is no specific or effective treatment. Its development involves dysregulated autophagy and unresolved inflammation, demonstrated by studies in genetic and experimental mouse models. Disease...

journal_title：Gastroenterology

authors： Gukovskaya AS,Gukovsky I,Algül H,Habtezion A

更新日期：2017-11-01 00:00:00